Methotrexate combined with Xanax

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 1/13/2006 Physician United States
Primary
Concomitant
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 2/3/2006 Physician United States
Primary
Concomitant
Sinusitis Other Serious 12/1/2005 Female 150 lb 2/13/2006 Consumer United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 9/1/2005 Female 3/1/2006 Physician United States
Primary
Concomitant
Neuropathy Hospitalization 12/2/2005 Female 146 lb 3/3/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/28/2004 75 Male 3/6/2006 Physician France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/4/2005 Male 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Photophobia Other Serious 3/16/2006 Male 240 lb 4/10/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/23/2006 Female 4/21/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2000 47 Female 161 lb 5/1/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2000 47 Female 161 lb 5/8/2006 Physician United States
Primary
Concomitant
Yellow Skin Other Serious 4/1/1997 Female 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2006 Female 5/11/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/23/2006 Female 5/19/2006 Physician United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Death 12/5/2005 80 Male 154 lb 5/23/2006
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 8/1/2005 Male 5/26/2006 Physician United States
Primary
Concomitant
Yellow Skin Other Serious 4/1/1997 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 1/1/2005 Female 160 lb 6/1/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/5/2005 80 Male 154 lb 6/7/2006
Primary
Concomitant
Vision Blurred Other Serious 1/1/2006 Female 154 lb 6/16/2006 Physician United States
Primary
Concomitant
Sarcoidosis Other Serious 6/1/2001 62 Female 6/14/2006 Consumer United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 8/1/2005 52 Female 6/7/2006 Consumer France
Primary
Concomitant
Pyrexia 5/27/2006 62 Female 93 lb 6/30/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 66 Female 6/5/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2006 Female 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/1/2002 Male 180 lb 8/7/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 12/30/2004 75 Male 8/2/2006 Physician France
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 6/30/2006 59 Male 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 4/1/2006 Female 123 lb 8/16/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/8/2006 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 7/11/2006 Female 103 lb 8/31/2006 Consumer United States
Primary
Concomitant
Death Other Serious Female 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/1/2002 Male 180 lb 9/27/2006 Physician United States
Primary
Concomitant
Pyrexia 5/27/2006 62 Female 93 lb 10/2/2006 Consumer United States
Primary
Concomitant
Skin Reaction Other Serious 10/1/2006 Female 200 lb 10/4/2006 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Unclassifiable Death Female 12/8/2006 Physician United States
Primary
Concomitant
Superior Sagittal Sinus Thrombosis Hospitalization 8/31/2006 Female 121 lb 12/18/2006 Pharmacist United States
Primary
Concomitant
Death Death 11/22/2006 77 Female 12/8/2006 Physician United States
Primary
Concomitant
Malaise 2/9/2006 Female 12/21/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Reaction Other Serious 5/3/2006 59 Female 130 lb 6/30/2006 Consumer United States
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 3/20/2007 Female 4/3/2007 Physician United States
Primary
Concomitant
Respiratory Arrest Death 11/22/2006 77 Female 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/5/2006 Female 4/5/2007 Physician United States
Primary
Concomitant
Visual Field Defect Other Serious 2/1/2007 Female 130 lb 3/19/2007 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2000 21 Female 5/24/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2007 Female 240 lb 7/3/2007 Physician United States
Primary
Concomitant
Neuralgia Other Serious 7/1/2006 Female 148 lb 7/17/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/10/2007 Male 238 lb 7/17/2007 Physician United States
Primary
Concomitant
Insomnia 3/27/2007 53 Female 115 lb 7/10/2007 Consumer United States
Primary
Concomitant
Dysgeusia 5/12/2007 74 Male 7/10/2007 Physician United States
Primary
Concomitant
Vision Blurred 5/12/2007 65 Male 7/11/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/6/2007 53 Female 107 lb 9/12/2007 United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 7/16/2007 56 Female 9/13/2007 Consumer United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 7/16/2007 56 Female 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Papular 7/17/2007 58 Male 205 lb 9/26/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 10/1/2006 53 Female 107 lb 10/1/2007 United States
Primary
Secondary
Concomitant
Rheumatoid Lung Hospitalization 8/1/2007 82 Female 154 lb 10/4/2007 Consumer United States
Primary
Concomitant
Chorioretinal Disorder Other Serious 10/16/2007 58 Male 11/9/2007 Consumer United States
Primary
Concomitant
Rash Macular Hospitalization 11/5/2007 Female 190 lb 11/6/2007 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/1/2007 Female 170 lb 12/5/2007 Physician United States
Primary
Concomitant
Reiter's Syndrome Other Serious 7/1/2006 Female 12/6/2007 Physician United States
Primary
Concomitant
Vulval Cancer Other Serious 1/1/2003 Female 185 lb 12/6/2007 Physician United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Hospitalization 10/1/2005 Female 206 lb 12/6/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/6/2006 Male 12/6/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2006 Female 148 lb 12/7/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 6/11/2007 Female 12/12/2007 Physician United States
Primary
Concomitant
Injection Site Warmth 8/1/2007 Female 12/13/2007 Other Health Professional
Primary
Concomitant
Urinary Tract Infection 8/27/2007 Female 12/15/2007 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 12/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 Female 190 lb 12/18/2007 Consumer United States
Primary
Secondary
Concomitant
Rhinorrhoea 8/1/2007 72 Female 181 lb 12/21/2007 Consumer United States
Primary
Concomitant
Respiratory Distress Other Serious 11/20/2007 35 Female 12/26/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/20/2007 35 Female 1/24/2008 Consumer United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 Female 143 lb 3/25/2008 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 6/27/2007 Female 326 lb 3/31/2008 Other Health Professional United States
Primary
Concomitant
Wheezing Death 1/19/2008 49 Male 154 lb 3/29/2008 Physician France
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 Female 143 lb 4/8/2008 Physician United States
Primary
Concomitant
Emotional Distress Other Serious 3/1/2008 Female 170 lb 4/10/2008 United States
Primary
Concomitant
Ventricular Fibrillation Death 1/1/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious 8/1/2007 81 Female 181 lb 4/11/2008 Physician United States
Primary
Concomitant
Fatigue 41 Female 161 lb 4/11/2008 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious Female 151 lb 5/12/2008 Physician United States
Primary
Secondary
Concomitant
Medication Residue 3/1/2007 5/13/2008 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious Female 151 lb 5/30/2008 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 151 lb 6/4/2008 Physician United States
Primary
Secondary
Concomitant
Viral Infection Life Threatening 6/1/2008 Female 145 lb 6/18/2008 Pharmacist United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 4/3/2003 Female 6/26/2008 Physician United States
Primary
Concomitant
Nausea 1/1/2007 38 Female 170 lb 6/30/2008 Consumer United States
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 6/8/2008 Male 141 lb 7/1/2008 Physician United States
Primary
Concomitant
Death Hospitalization 6/8/2008 Male 141 lb 7/18/2008 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious Female 151 lb 8/1/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/19/2008 71 Female 151 lb 7/9/2008 Physician United States
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 4/9/2008 Male 174 lb 8/7/2008 Physician United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Hospitalization 4/20/2006 Female 8/19/2008 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 1/14/2008 71 Female 151 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2007 63 Male 8/25/2008 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious Female 150 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/17/2006 72 Female 147 lb 9/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased Life Threatening 1/1/2007 63 Male 241 lb 9/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2006 Female 134 lb 9/19/2008 Physician United States
Primary
Concomitant
Fungal Infection 3/10/2008 56 Female 9/25/2008 Consumer United States
Primary
Concomitant
Malignant Melanoma Life Threatening 1/1/2007 59 Female 119 lb 9/25/2008 Consumer United States
Primary
Secondary
Concomitant
Xanthochromia Hospitalization 6/5/2008 Male 162 lb 10/13/2008 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2008 67 Female 10/7/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 6/5/2008 27 Male 163 lb 11/3/2008 Physician United States
Primary
Secondary
Pyrexia Hospitalization 6/5/2008 27 Male 163 lb 11/6/2008 Physician United States
Primary
Secondary
Application Site Irritation 8/12/2008 59 Female 11/10/2008 Consumer United States
Primary
Concomitant
Rash Macular Hospitalization 11/5/2007 Female 190 lb 11/10/2008 United States
Primary
Secondary
Concomitant
Injection Site Erythema 12/10/2007 Female 11/17/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 6/5/2008 27 Male 163 lb 11/25/2008 Physician United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 1/1/2008 Female 11/21/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 6/5/2008 27 Male 162 lb 11/26/2008 Physician United States
Primary
Secondary
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 11/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 11/26/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/15/2008 Female 11/26/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 5/1/2008 33 Female 11/26/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Optic Neuropathy Other Serious Female 170 lb 12/1/2008 Physician United States
Primary
Concomitant
Myalgia 1/18/2008 Female 12/1/2008 Physician United States
Primary
Concomitant
Odynophagia Hospitalization 8/28/2008 43 Female 12/4/2008 Other Health Professional France
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 6/25/2008 27 Male 162 lb 12/1/2008 Physician United States
Primary
Secondary
Concomitant
Injection Site Pruritus 12/19/2007 Female 12/10/2008 Other Health Professional
Primary
Concomitant
Pain 4/14/2008 Female 12/11/2008 Physician United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 6/25/2008 27 Male 162 lb 12/10/2008 United States
Primary
Secondary
Injection Site Warmth 12/10/2007 Female 12/17/2008 Physician United States
Primary
Concomitant
Malignant Melanoma Life Threatening 1/1/2007 59 Female 119 lb 12/31/2008 Consumer United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 12/10/2008 Female 147 lb 1/14/2009 Physician United States
Primary
Concomitant
Weight Increased 1/1/2008 67 Female 137 lb 1/13/2009 Consumer United States
Primary
Concomitant
Productive Cough Hospitalization 11/1/2008 Female 2/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/20/2009 Male 112 lb 2/18/2009 Physician France
Primary
Concomitant
Vision Blurred 3/25/2008 40 Female 2/27/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/21/2009 Male 190 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Skin Discolouration Female 158 lb 3/13/2009 Consumer Puerto Rico
Primary
Concomitant
Injection Site Irritation 11/18/2008 Male 178 lb 3/14/2009 Other Health Professional United States
Primary
Concomitant
Viral Infection 11/12/2008 Female 112 lb 3/14/2009 Other Health Professional United States
Primary
Concomitant
Wound Secretion 12/2/2008 Female 3/14/2009 Physician United States
Primary
Concomitant
Vitamin D Decreased 1/1/2009 Female 160 lb 3/14/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/20/2009 Male 112 lb 3/19/2009 Physician France
Primary
Concomitant
Plantar Fasciitis Other Serious 1/1/2009 Female 183 lb 4/10/2009 Physician United States
Primary
Concomitant
Thrombocythaemia Other Serious 11/1/2008 Female 157 lb 4/10/2009 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 2/9/2000 50 Female 213 lb 4/14/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 Male 146 lb 4/23/2009 Other Health Professional France
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2006 Female 147 lb 4/28/2009 Physician United States
Primary
Concomitant
Insulin-requiring Type 2 Diabetes Mellitus Other Serious 4/29/2002 50 Female 388 lb 6/1/2009 United States
Primary
Concomitant