Ciprofloxacin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Tract Infection Hospitalization 9/1/2005 47 Female 152 lb 1/24/2006 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 11/14/2005 20 Female 218 lb 1/26/2006 Pharmacist United Kingdom
Primary
Concomitant
Hepatitis Fulminant Other Serious Unknown 1/31/2006 Germany
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious Unknown 1/31/2006 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/26/2004 Male 121 lb 2/17/2006 Physician United Kingdom
Primary
Concomitant
Paraesthesia Hospitalization 12/4/2005 21 Male 159 lb 2/17/2006 United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/1/2006 Male 150 lb 5/5/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/5/2006 Physician Germany
Primary
Concomitant
Respiratory Failure Death 2/26/2006 Female 101 lb 5/8/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 5/8/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/8/2006 Physician Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/1/2006 Male 150 lb 5/8/2006 Physician Germany
Primary
Concomitant
Respiratory Failure Death 2/26/2006 Female 101 lb 5/23/2006 Physician Germany
Primary
Concomitant
Right Ventricular Failure Death 2/26/2006 Female 101 lb 6/7/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 6/7/2006 Physician Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/1/2006 Male 150 lb 6/7/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 6/7/2006 Physician Germany
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/7/2005 83 Male 165 lb 7/17/2006 Denmark
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Infection Other Serious 6/26/2004 Male 121 lb 9/18/2006 Physician United Kingdom
Primary
Concomitant
Intestinal Ischaemia Other Serious 9/11/2006 77 Male 11/2/2006 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 7/6/2006 77 Male 11/10/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 10/11/2006 Female 1/16/2007 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Hospitalization 11/28/2006 72 Female 2/9/2007 France
Primary
Secondary
Concomitant
Staphylococcal Infection Death 74 Female 2/7/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/24/2006 Male 126 lb 3/19/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/9/2006 Male 71 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Pseudomembranous Colitis Life Threatening 7/29/2005 89 Female 3/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pseudomembranous Colitis Life Threatening 7/29/2005 89 Female 4/11/2007 Physician Japan
Primary
Secondary
Concomitant
Bladder Cancer Hospitalization Male 163 lb 4/12/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Other Serious Male 4/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 12 Female 4/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/27/2006 30 Female 90 lb 7/3/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/27/2006 30 Female 90 lb 7/3/2007 Japan
Primary
Secondary
Concomitant
Malaise Other Serious 9/1/2004 Female 238 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/27/2006 30 Female 90 lb 7/12/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5 Female 8/18/2007 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 12/1/2006 Female 156 lb 9/7/2007 Physician United States
Primary
Concomitant
Melaena Other Serious 3/2/2007 43 Male 132 lb 9/17/2007 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Death 54 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 61 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 79 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/12/2007 70 Male 196 lb 10/1/2007 Physician United States
Primary
Secondary
Concomitant
Tendonitis 10/5/2007 Female 190 lb 12/14/2007 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 12/18/2007 Female 249 lb 1/11/2008 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 9/24/2007 46 Female 146 lb 1/24/2008 United Kingdom
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Productive Cough Other Serious 1/31/2008 71 Male 176 lb 2/29/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/20/2007 Male 117 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/31/2008 71 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 1/31/2008 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Back Pain Female 112 lb 3/15/2008 United States
Primary
Concomitant
Injection Site Pain 2/21/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Wound Secretion Other Serious 70 Male 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious Male 176 lb 4/21/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 10/19/2004 Male 161 lb 6/30/2008 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Mass Other Serious 7/8/2008 Male 7/18/2008 China
Primary
Concomitant
Pulmonary Mass Other Serious 7/8/2008 Male 8/1/2008 China
Primary
Concomitant
Staphylococcal Infection Other Serious 70 Male 8/4/2008 United States
Primary
Concomitant
Venoocclusive Disease Other Serious 8/12/2008 Canada
Primary
Secondary
Concomitant
Mycobacterium Chelonei Infection Other Serious 70 Male 8/12/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Stomatitis Death 44 Male 8/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/21/2008 Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 1/1/2007 53 Male 8/29/2008 Physician Poland
Primary
Concomitant
Septic Shock Life Threatening 1/1/2007 53 Male 9/5/2008 Physician Poland
Primary
Concomitant
Pulmonary Mass Other Serious 7/8/2008 Male 9/8/2008 China
Primary
Concomitant
Salmonellosis Hospitalization 8/17/2004 Female 101 lb 9/12/2008 France
Primary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
Vomiting Hospitalization 13 Male 9/17/2008
Primary
Concomitant
Superinfection Hospitalization 69 Male 9/17/2008
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2006 Female 134 lb 9/19/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease 9/15/2008 Female 10 lb 9/19/2008 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/29/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 9/15/2008 Female 10 lb 9/30/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 10/16/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 166 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 151 lb 11/17/2008 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 53 Male 11/21/2008
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 4 Female 11/21/2008
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 11/24/2008 Consumer France
Primary
Secondary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 11/26/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/20/2008 Female 141 lb 12/5/2008 Mexico
Primary
Concomitant
Vomiting Other Serious 64 Male 1/12/2009
Primary
Secondary
Concomitant
Osteosclerosis Required Intervention 10/3/2007 Female 12/31/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2008 Female 80 lb 1/23/2009 United States
Primary
Concomitant
Pneumonia Other Serious 8/1/2008 Female 139 lb 2/3/2009 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/25/2008 62 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Staphylococcal Sepsis Other Serious 51 Male 5/12/2009
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 10/28/2008 Female 11/4/2008 United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 43 5/25/2009 Other Health Professional Canada
Primary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 5/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Oedema Peripheral 8/1/2008 Female 140 lb 6/11/2009 United States
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 3/26/2008 Male 6/11/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 6/17/2009 Female 167 lb 7/10/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/17/2009 Female 167 lb 7/20/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Required Intervention 16 Female 7/16/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Apnoea Other Serious 9/10/2008 48 Female 7/22/2009 Consumer United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 6/26/2009 65 Female 198 lb 10/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Death 3/2/2008 78 Female 10/17/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/24/2009 69 Female 10/21/2009 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Hemiplegia Other Serious 8/11/2009 16 Male 11/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 12/1/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/8/2009 58 Female 106 lb 12/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Psychomotor Seizures Other Serious 9/17/2009 27 Male 1/6/2010 Other Health Professional Germany
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 11/12/2009 Female 15 lb 12/30/2009 United States
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 12/6/2009 Female 117 lb 1/25/2010 Physician Mexico
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 12/6/2009 Female 117 lb 1/29/2010 Physician Mexico
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 12/6/2009 Female 118 lb 3/11/2010 Physician Mexico
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/29/2009 Male 185 lb 3/15/2010 Physician Poland
Primary
Secondary
Concomitant
Proctitis Hospitalization 8/1/2009 Male 150 lb 3/24/2010 Brazil
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/8/2009 58 Female 106 lb 3/25/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Venous Injury Life Threatening 12/6/2009 Female 118 lb 3/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 8/5/2009 Male 185 lb 3/31/2010 Physician Poland
Primary
Secondary
Concomitant
Renal Failure Life Threatening 11/1/2009 38 Female 4/9/2010 Other Health Professional Switzerland
Primary
Secondary
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 4/14/2010 United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 11/1/2009 38 Female 4/20/2010 Other Health Professional Switzerland
Primary
Secondary
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization Male 126 lb 4/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/21/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 53 Female 165 lb 6/4/2010 Consumer Brazil
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 6/9/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 144 lb 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 144 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 3/24/2010 56 Female 205 lb 7/8/2010 Physician Lithuania
Primary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 5/30/2010 57 Male 204 lb 7/14/2010 Other Health Professional Russian Federation
Primary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 62 Male 132 lb 8/20/2010
Primary
Secondary
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/20/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/24/2010 United States
Primary
Secondary
Concomitant

Drug Data