Epirubicin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 5/29/2005 68 Female 110 lb 1/5/2006 Physician Japan
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 12/13/2005 58 Female 1/20/2006 France
Primary
Secondary
Vomiting Hospitalization 5/29/2005 68 Female 110 lb 1/25/2006 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 8/12/2005 67 Female 181 lb 2/6/2006 Physician Germany
Primary
Secondary
Vomiting Hospitalization 5/29/2005 68 Female 50 lb 2/6/2006 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 1/1/2005 51 Female 2/8/2006 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Vomiting Hospitalization 5/4/2005 49 Female 3/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/8/2006 68 Female 126 lb 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
Productive Cough Hospitalization 2/8/2006 68 Female 126 lb 4/7/2006 United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 10/3/2005 39 Female 128 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Swelling Other Serious 12/1/2004 64 Female 143 lb 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/1/2006 Female 181 lb 5/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/24/2006 Physician United Kingdom
Primary
Concomitant
Swelling Other Serious 4/13/2006 51 Female 5/24/2006 Physician Portugal
Primary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Dysgeusia Other Serious Female 8/14/2006 Consumer United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/1/2006 53 Male 9/15/2006 Physician Japan
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 1/1/2006 53 Male 9/27/2006 Pharmacist Japan
Primary
Secondary
Osteonecrosis Hospitalization 12/21/2004 58 Female 173 lb 10/13/2006 Physician United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 12/12/2006 Physician United Kingdom
Primary
Concomitant
T-cell Type Acute Leukaemia Death 1/1/2003 38 Female 1/10/2007 Physician Greece
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Hospitalization 66 Female 2/26/2007
Primary
Secondary
Concomitant
Ureteric Obstruction Hospitalization 66 Female 2/22/2007 Physician Italy
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 66 2/19/2007 Italy
Primary
Secondary
Cardiomyopathy Other Serious 1/1/2004 57 Female 3/1/2007 Other Health Professional Germany
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 66 Female 3/2/2007 Other Health Professional Italy
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 66 Female 3/5/2007 Consumer Japan
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 66 Female 3/13/2007 Consumer United States
Primary
Secondary
Sepsis Hospitalization 1/27/2007 Female 134 lb 3/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/16/2006 Female 169 lb 3/19/2007 Physician United Kingdom
Primary
Secondary
Stomatitis Life Threatening 1/29/2007 68 Male 3/22/2007 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Morphology Abnormal Other Serious 51 Female 3/29/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Hospitalization 1/1/2006 66 Female 4/11/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious Unknown 4/16/2007 Germany
Primary
Secondary
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/12/2007 Physician United Kingdom
Primary
Concomitant
Stem Cell Transplant Other Serious 51 Female 5/8/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Dyspnoea Other Serious 2/12/2007 55 Female 170 lb 5/21/2007 Consumer United States
Primary
Secondary
Pulmonary Embolism Death Female 6/2/2007 Physician Germany
Primary
Secondary
Pyrexia Life Threatening 12/16/2006 59 Female 6/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 74 Male 8/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 59 Female 8/17/2007 Japan
Primary
Secondary
Rash Pruritic Other Serious 74 Male 10/11/2007 United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 3/1/2003 Male 10/17/2007
Primary
Secondary
Rash Pruritic Other Serious 74 Male 10/19/2007 Other Health Professional United States
Primary
Secondary
Rash Pruritic Other Serious 74 Male 10/17/2007 United States
Primary
Secondary
Neutropenic Sepsis Hospitalization 69 Female 11/27/2007 Pharmacist United Kingdom
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2007 74 Male 12/5/2007 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/12/2000 42 Female 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 59 Female 4/24/2008 Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/16/2006 59 Female 8/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/3/2008 Female 10/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Deafness Disability 8/18/2008 Female 193 lb 10/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/3/2008 52 Female 11/3/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/3/2008 Female 11/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/3/2008 52 Female 11/19/2008 Physician United States
Primary
Secondary
Deafness Disability 8/18/2008 46 Female 11/17/2008 United Kingdom
Primary
Secondary
Concomitant
Deafness Disability 8/18/2008 46 Female 192 lb 11/26/2008 United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Disability 8/18/2008 Female 193 lb 12/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/1/2004 69 Female 12/16/2008 Consumer United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 70 Female 1/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 70 Female 12/30/2008 Canada
Primary
Secondary
Pyrexia Hospitalization 7/16/2007 54 Female 4/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Temporal Arteritis Hospitalization 3/1/2009 Female 5/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Colitis Other Serious 61 Female 5/15/2009
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 60 Female 5/20/2009 Other Health Professional South Africa
Primary
Secondary
Stomatitis Other Serious 5/29/2009 Physician Greece
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 60 Female 6/4/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Pancytopenia Other Serious 1/1/2007 Female 6/5/2009 Physician United Kingdom
Primary
Concomitant
Stomatitis Other Serious 6/12/2009 Physician Greece
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2004 Female 173 lb 8/6/2009 Physician United Kingdom
Primary
Concomitant
Tinnitus Other Serious 8/14/2009 Physician Greece
Primary
Concomitant
Myocardial Infarction Death 8/14/2009 Physician Greece
Primary
Concomitant
Febrile Neutropenia Other Serious 8/14/2009 Physician Greece
Primary
Concomitant
Neutropenia Other Serious 8/14/2009 Physician Greece
Primary
Concomitant
Neutropenia Other Serious 8/14/2009 Physician Greece
Primary
Concomitant
Pyrexia Hospitalization 7/20/2009 Female 137 lb 9/9/2009 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/23/2009 9/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Procedural Complication Required Intervention 55 Female 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 1/23/2009 10/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2007 Female 12/1/2009 Physician United Kingdom
Primary
Concomitant
Sepsis Other Serious 55 Female 12/17/2009 Consumer United Kingdom
Primary
Secondary
Neutropenia Other Serious 12/29/2009 United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/25/2010 Other Health Professional Japan
Primary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/31/2010 Other Health Professional Japan
Primary
Concomitant
Uterine Cancer Other Serious 2/11/2009 71 Female 3/30/2010 Switzerland
Primary
Secondary
Pleural Effusion Other Serious 9/2/2009 49 Female 5/28/2010 Consumer United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 9/2/2009 49 Female 165 lb 8/23/2010 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 9/10/2010 Other Health Professional Greece
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 8/1/2009 50 Female 172 lb 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Deafness Neurosensory Disability 8/1/2009 50 Female 172 lb 11/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Deafness Neurosensory Disability 8/1/2009 50 Female 10/26/2010 United Kingdom
Primary
Secondary
Concomitant
Rectal Ulcer Other Serious 59 Male 12/23/2010 Physician Japan
Primary
Secondary
Rectal Ulcer Other Serious 59 Male 1/27/2011 Physician Japan
Primary
Secondary
Rectal Ulcer Other Serious 59 Male 2/22/2011 Physician Japan
Primary
Secondary
Syndactyly Congenital Anomaly 39 Male 1 lb 4/11/2011 Physician Belgium
Primary
Secondary
Concomitant
Clinodactyly Congenital Anomaly 39 Male 4/12/2011 Other Health Professional Belgium
Primary
Secondary
Congenital Musculoskeletal Anomaly Congenital Anomaly 39 Male 4/12/2011 Other Health Professional Belgium
Primary
Secondary
Clinodactyly Congenital Anomaly 39 Male 4/12/2011 Other Health Professional Belgium
Primary
Secondary
Micrognathia Congenital Anomaly 39 Male 4/12/2011 Other Health Professional Belgium
Primary
Secondary
Haemangioma Other Serious Male 4/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Premature Labour Other Serious 4/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 4/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 4/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Abortion Induced Hospitalization 39 Female 4/20/2011 Other Health Professional Belgium
Primary
Secondary
Clinodactyly Congenital Anomaly Male 4/20/2011 Other Health Professional Belgium
Primary
Secondary
Micrognathia Death 0 Male 1 lb 4/27/2011 Physician Belgium
Primary
Secondary
Hemiparesis Hospitalization 4 Male 4/29/2011 Taiwan, Province Of China
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Male 4/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Haemangioma Other Serious Male 4/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Male 4/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Male 4/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Progression Death Female 4/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Maternal Drugs Affecting Foetus Other Serious Male 4/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Red Blood Cells Csf Positive Other Serious 4 Male 5/9/2011 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 4 Male 5/5/2011 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 5/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Superior Sagittal Sinus Thrombosis Other Serious 4 Male 5/17/2011 Physician Taiwan, Province Of China
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/18/2011 Physician United Kingdom
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Ischaemic Stroke Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Other Serious Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Oedema Peripheral Hospitalization 10 Female 5/18/2011 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious Female 6/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Ischaemic Stroke Other Serious Female 5/25/2011 United Kingdom
Primary
Secondary

Drug Data