Methotrexate combined with Methylprednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sudden Death Death 6/3/2005 1/2/2006 Physician United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Other Serious 12/12/2005 54 Female 125 lb 1/6/2006 Physician United States
Primary
Secondary
Concomitant
Hepatomegaly Hospitalization 3/23/2005 46 Female 1/12/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/22/2005 Female 117 lb 1/12/2006 Czech Republic
Primary
Concomitant
Pyrexia Other Serious 10/1/2005 Male 1/16/2006 Czech Republic
Primary
Secondary
Concomitant
Pyelonephritis Acute Hospitalization 1/9/2006 59 Female 143 lb 1/24/2006 Romania
Primary
Concomitant
Respiratory Distress Hospitalization 12/9/2005 72 Male 163 lb 1/20/2006 Physician France
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2005 Female 149 lb 1/26/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/27/2005 Female 115 lb 2/2/2006 Italy
Primary
Concomitant
Skin Ulcer Hospitalization 1/4/2005 57 Female 143 lb 2/8/2006 Germany
Primary
Concomitant
Depression Other Serious 10/19/2005 24 Female 110 lb 2/10/2006 Physician Germany
Primary
Secondary
Concomitant
Tuberculin Test Positive Other Serious 11/22/2005 Female 117 lb 2/10/2006 Czech Republic
Primary
Concomitant
Post Procedural Complication Death 34 Male 2/7/2006 Physician Japan
Primary
Concomitant
Hemiplegia Death 34 Male 2/16/2006 Physician Japan
Primary
Concomitant
Vertigo Other Serious 10/1/2005 Male 234 lb 2/27/2006 Physician Portugal
Primary
Concomitant
Oedema Peripheral Other Serious 5/11/2005 Female 110 lb 2/28/2006 Physician Hungary
Primary
Concomitant
Wound Dehiscence Hospitalization 63 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Wound Dehiscence Hospitalization 63 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Tuberculosis Gastrointestinal Hospitalization 56 Male 176 lb 3/2/2006 Physician Greece
Primary
Concomitant
Rectal Lesion Hospitalization 4/12/2005 Male 137 lb 3/3/2006 Italy
Primary
Concomitant
Pseudomonal Sepsis Other Serious 46 Male 2/22/2006 Physician Japan
Primary
Concomitant
Transaminases Increased Other Serious 19 Female 3/4/2006 Physician Korea, Republic Of
Primary
Concomitant
Paraesthesia Other Serious 12/30/2005 55 Female 166 lb 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 5/27/2005 Female 115 lb 3/8/2006 Italy
Primary
Concomitant
Rectal Lesion Hospitalization 4/12/2005 Male 137 lb 3/15/2006 Italy
Primary
Concomitant
Shock Other Serious 1/1/2002 Female 3/17/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Spinal Myelogram Abnormal Other Serious 34 Female 3/21/2006 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 2/1/2006 Female 66 lb 3/22/2006 Physician Korea, Republic Of
Primary
Concomitant
Lacunar Infarction Other Serious 12/30/2005 55 Female 166 lb 3/16/2006 Physician United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 6/21/2005 53 Female 3/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 57 Male 3/15/2006 Physician Japan
Primary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2004 Female 3/30/2006 Other Health Professional Finland
Primary
Concomitant
Wound Dehiscence Life Threatening 63 Male 3/24/2006 Consumer United Kingdom
Primary
Secondary
Tumour Invasion Other Serious 12/12/2005 54 Female 125 lb 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Lacunar Infarction Other Serious 12/30/2005 55 Female 166 lb 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Tuberculin Test Positive Other Serious 11/22/2005 Female 117 lb 4/3/2006 Physician Czech Republic
Primary
Concomitant
Mucormycosis Death 12/1/2004 51 Male 3/24/2006 Physician Japan
Primary
Concomitant
Pseudomonal Sepsis Other Serious 4/17/2002 46 Male 143 lb 3/29/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 12/26/2005 Female 4/11/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Urticaria Hospitalization 4/4/2006 Female 165 lb 4/13/2006 Physician Hungary
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/13/2003 56 Female 181 lb 4/14/2006 Lawyer United States
Primary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization 3/27/2006 70 Male 146 lb 4/11/2006 Physician France
Primary
Secondary
Concomitant
Sepsis Death 3/25/2006 47 Female 4/13/2006 Physician Indonesia
Primary
Concomitant
Urticaria Hospitalization 4/4/2006 Female 165 lb 4/26/2006 Physician Hungary
Primary
Concomitant
Sigmoiditis Hospitalization 3/27/2006 70 Male 146 lb 4/20/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 58 Male 4/20/2006
Primary
Concomitant
Paraesthesia Other Serious 12/30/2005 55 Female 166 lb 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 12/19/2005 56 Female 220 lb 2/28/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 55 Female 5/25/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization 3/27/2006 70 Male 146 lb 5/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vertigo Hospitalization 5/17/2006 Female 134 lb 5/25/2006 Physician Italy
Primary
Concomitant
Unevaluable Event Death 3/25/2006 47 Female 5/24/2006 Physician Indonesia
Primary
Concomitant
Renal Colic Hospitalization 10/28/2005 Male 209 lb 6/2/2006 Italy
Primary
Concomitant
Pulmonary Hypertension Other Serious 55 Female 5/23/2006
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 57 Female 5/23/2006 Italy
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Death 34 Male 5/23/2006 Physician Japan
Primary
Concomitant
Malaise Hospitalization 2/16/2006 Male 6/12/2006 Physician Belgium
Primary
Concomitant
Drug Interaction Required Intervention 10/5/2004 55 Female 115 lb 6/7/2006 Physician Italy
Primary
Concomitant
Drug Interaction Required Intervention 12/28/2004 57 Female 121 lb 6/7/2006 Physician Italy
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 6/27/2006 Physician Japan
Primary
Concomitant
Malaise Hospitalization 1/1/2005 12 Female 6/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vascular Skin Disorder Other Serious 35 Male 7/6/2006 Other Health Professional Poland
Primary
Secondary
Vomiting Hospitalization 6/21/2006 82 Male 174 lb 7/6/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/2/2006 Male 9 lb 7/5/2006 United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 6/9/2006 Female 141 lb 7/12/2006 Italy
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious Female 7/13/2006 Other Health Professional Lithuania
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious Female 7/13/2006 Physician Lithuania
Primary
Concomitant
Vascular Skin Disorder Other Serious 35 Male 7/6/2006 Physician Poland
Primary
Secondary
Wound Secretion Hospitalization 3/27/2006 70 Male 146 lb 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Wheezing Hospitalization 6/21/2006 82 Male 174 lb 7/20/2006 Physician United States
Primary
Concomitant
Visual Field Defect Other Serious Female 7/13/2006
Primary
Secondary
Concomitant
Haemangioma Other Serious 35 Male 7/27/2006 Other Health Professional Poland
Primary
Secondary
Wheezing Hospitalization 6/21/2006 82 Male 174 lb 7/28/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/4/2005 Female 7/28/2006 Physician Belgium
Primary
Concomitant
Respiratory Failure Other Serious 12/26/2005 Female 8/3/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Cerebral Atrophy Hospitalization 11/9/2004 68 Female 106 lb 8/7/2006 Physician France
Primary
Secondary
Vomiting Other Serious 17 Female 8/15/2006 Other Health Professional India
Primary
Secondary
Vomiting Other Serious 17 Female 8/15/2006 Other Health Professional India
Primary
Secondary
Rectal Lesion Hospitalization 4/12/2005 Male 137 lb 8/16/2006 Italy
Primary
Concomitant
Rectal Lesion Hospitalization 4/12/2005 Male 137 lb 8/16/2006 Italy
Primary
Concomitant
Bronchitis Hospitalization 9/12/2005 Female 8/18/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Other Serious 17 Female 8/15/2006 Physician India
Primary
Secondary
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/13/2006 Female 158 lb 8/25/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Other Serious 35 Male 8/24/2006
Primary
Secondary
White Blood Cell Count Increased Other Serious 12/29/2003 60 Female 9/5/2006 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 12/30/2005 55 Female 166 lb 9/11/2006 Physician United States
Primary
Secondary
Concomitant
Synovitis Hospitalization 8/28/2006 Female 9/25/2006 Physician Czech Republic
Primary
Concomitant
Drug Interaction Required Intervention 10/5/2004 55 Female 115 lb 9/25/2006 Italy
Primary
Concomitant
Drug Interaction Required Intervention 12/28/2004 57 Female 121 lb 9/25/2006 Italy
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/4/2005 Female 10/4/2006 Physician Belgium
Primary
Concomitant
Bladder Cancer Other Serious 6/9/2006 Female 141 lb 10/4/2006 Italy
Primary
Concomitant
Trichosporon Infection Death 42 Male 10/9/2006 Japan
Primary
Secondary
Concomitant
Melaena Other Serious 1/1/2004 41 Female 10/17/2006 Japan
Primary
Secondary
Concomitant
Trichosporon Infection Death 42 Male 10/17/2006 Japan
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization 3/27/2006 70 Male 146 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 42 Female 10/27/2006 Physician Turkey
Primary
Secondary
Tricuspid Valve Incompetence Hospitalization 12/23/2003 55 Female 126 lb 10/27/2006 United States
Primary
Concomitant
Respiratory Failure Hospitalization 3/31/2006 67 Male 10/31/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization Male 11/9/2006 Physician Belgium
Primary
Concomitant
General Physical Health Deterioration Other Serious 10/1/2005 Male 11/13/2006 Physician Belgium
Primary
Secondary
Concomitant
Bronchitis Hospitalization 9/12/2005 Female 11/14/2006 Physician United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 6/1/1994 38 Male 11/15/2006 Other Health Professional Turkey
Primary
Secondary
Concomitant
Pulmonary Mass Other Serious 8/2/2006 Male 11/16/2006 Physician Belgium
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/15/2006 Female 119 lb 11/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prurigo Hospitalization 9/1/2006 Female 121 lb 11/17/2006 Italy
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/15/2006 Female 119 lb 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombophlebitis Other Serious 1/1/2003 34 Female 11/21/2006 Japan
Primary
Concomitant
Pancreatic Enzymes Abnormal Other Serious 1/18/2006 Female 11/21/2006 Physician Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 16 Female 11/27/2006
Primary
Secondary
Concomitant
Infection Hospitalization 9/1/2006 Female 121 lb 11/28/2006 Italy
Primary
Concomitant
Pancreatic Enzymes Abnormal 1/18/2006 Female 12/1/2006 Physician Belgium
Primary
Concomitant
Prostate Cancer Hospitalization 7/19/2006 Male 12/7/2006 Physician Belgium
Primary
Concomitant
Tendon Rupture Hospitalization 11/1/2005 Female 12/11/2006 Physician Belgium
Primary
Concomitant
White Blood Cell Count Increased Death 9/21/2006 41 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Psoriasis Other Serious 11/4/2006 Female 12/14/2006 Physician Hungary
Primary
Concomitant
Viral Infection Hospitalization 12/23/2003 55 Female 126 lb 12/6/2006 Other Health Professional United States
Primary
Concomitant
Increased Tendency To Bruise 51 Female 154 lb 12/22/2006 Consumer United States
Primary
Concomitant
Synovial Fluid Analysis Hospitalization 8/26/2006 Male 12/22/2006 Other Health Professional Belgium
Primary
Concomitant
Viral Myocarditis Death 9/21/2006 41 Female 12/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 144 lb 12/29/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 3/12/2004 57 Female 137 lb 12/29/2006 Physician France
Primary
Secondary
Concomitant
Vasculitis Hospitalization 6/1/2004 Male 236 lb 1/10/2007 Physician Luxembourg
Primary
Concomitant
Oligodendroglioma Hospitalization 3/18/2005 66 Female 181 lb 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Progesterone Receptor Assay Positive Other Serious 12/12/2005 54 Female 125 lb 3/6/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/21/2006 41 Female 123 lb 3/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Cord Disorder Other Serious 3/29/2007 Consumer France
Primary
Secondary
Subcutaneous Emphysema Other Serious 3/1/2003 53 Female 3/31/2007 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 2/16/2007 66 Female 5/11/2007 Physician Spain
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious Male 5/29/2007 Physician Japan
Primary
Concomitant
Hypertrophic Cardiomyopathy Hospitalization 4/17/2007 8 Male 5/31/2007 France
Primary
Secondary
Concomitant
Gastrointestinal Disorder Hospitalization 4/21/2006 Male 6/20/2007 Consumer Belgium
Primary
Secondary
Concomitant
Surgery Hospitalization 13 Female 6/22/2007 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 16 Female 6/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/16/2007 66 Female 6/25/2007 Physician Spain
Primary
Secondary
Concomitant
Breast Cancer Other Serious 6/21/2005 Female 6/26/2007 Physician United States
Primary
Secondary
Concomitant
Rectosigmoid Cancer Other Serious 8/22/2006 Male 234 lb 6/29/2007 Physician Czech Republic
Primary
Concomitant
Parvovirus Infection Other Serious 7 Female 7/12/2007 Consumer United States
Primary
Secondary
Concomitant
Colon Cancer Other Serious 8/22/2006 Male 234 lb 7/12/2007 Physician Czech Republic
Primary
Concomitant
Vomiting Hospitalization 4/4/2007 Male 26 lb 7/13/2007 Physician Slovenia
Primary
Concomitant
Encephalopathy Other Serious 12 Female 7/13/2007 Japan
Primary
Secondary
Parvovirus Infection Death 7 Female 7/14/2007 Physician Greece
Primary
Secondary
Bradycardia Hospitalization 7/5/2007 Female 176 lb 7/18/2007 Other Health Professional United States
Primary
Concomitant
Parvovirus Infection Death 7 Female 55 lb 7/23/2007 Physician Greece
Primary
Secondary
Inflammation Hospitalization 4/12/2005 Male 137 lb 7/25/2007 Italy
Primary
Concomitant
Pancreatic Carcinoma Hospitalization 5/1/2007 Female 126 lb 7/26/2007 Italy
Primary
Concomitant
Breast Cancer Required Intervention 10/21/2003 58 Female 118 lb 7/5/2007 United States
Primary
Secondary
Concomitant

Drug Data