Ativan combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Noncompliance Other Serious 1/1/2005 44 Female 1/4/2006 Other Health Professional United States
Primary
Concomitant
Herpes Zoster Other Serious 1/1/2005 Female 120 lb 1/9/2006 Physician United States
Primary
Concomitant
Tongue Disorder Hospitalization 9/28/2005 75 Female 115 lb 11/19/2005 Pharmacist United States
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 10/14/2005 55 Male 11/15/2005 Other Health Professional United States
Primary
Concomitant
Blood Creatinine Increased Required Intervention 10/10/2005 32 Male 11/15/2005 Other Health Professional United States
Primary
Concomitant
Renal Failure Required Intervention 8/25/2005 61 Male 11/15/2005 Other Health Professional United States
Primary
Concomitant
Renal Failure Required Intervention 11/9/2005 46 Male 11/15/2005 United States
Primary
Concomitant
Renal Failure Acute Required Intervention 10/29/2005 40 Female 11/15/2005 Other Health Professional United States
Primary
Concomitant
Renal Impairment Required Intervention 11/5/2005 54 Female 11/15/2005 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Hospitalization 11/16/2002 17 Female 125 lb 2/7/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 1/31/2006 Male 194 lb 2/8/2006 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 10/14/2005 55 Male 2/8/2006 Other Health Professional United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 10/10/2005 32 Male 2/8/2006 Other Health Professional United States
Primary
Concomitant
Renal Impairment Hospitalization 11/5/2005 54 Female 2/8/2006 Other Health Professional United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 1/31/2006 Male 194 lb 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 1/31/2006 Male 194 lb 2/23/2006 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 10/14/2005 55 Male 2/21/2006 Other Health Professional United States
Primary
Concomitant
Renal Impairment Hospitalization 11/5/2005 54 Female 2/21/2006 Other Health Professional United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 1/31/2006 Male 194 lb 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/1/2006 Female 170 lb 3/14/2006 Other Health Professional Canada
Primary
Concomitant
Pyrexia Other Serious 12/12/2005 Male 194 lb 3/17/2006 Other Health Professional Canada
Primary
Concomitant
Pleural Effusion Hospitalization 6/4/2005 Male 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 3/24/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 9/14/2001 Female 253 lb 4/26/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/2/2006 Male 9 lb 7/5/2006 United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 4/1/2006 Female 6/30/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Clearance Decreased Required Intervention 2/24/2004 17 Male 152 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 7/20/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Other Serious 1/28/2002 Female 145 lb 8/2/2006 Physician United States
Primary
Concomitant
Exposure To Toxic Agent Hospitalization 6/22/2006 Male 143 lb 8/3/2006 Physician United States
Primary
Concomitant
Abdominal Pain Hospitalization 5/4/2006 Male 143 lb 8/3/2006 Physician United States
Primary
Concomitant
Hypertension Hospitalization 7/25/2006 32 Female 8/8/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 4/1/2006 Female 123 lb 8/16/2006 Physician United States
Primary
Concomitant
Breast Cancer Life Threatening 4/14/2006 Female 242 lb 9/18/2006 Physician United States
Primary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 9/21/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Other Serious 1/28/2002 Female 145 lb 10/6/2006 Physician United States
Primary
Concomitant
Myelopathy Other Serious 8/1/2006 Female 10/9/2006 Pharmacist United States
Primary
Concomitant
Heart Rate Increased 5/15/2006 55 Female 7/31/2006 Consumer United States
Primary
Concomitant
Pregnancy Other Serious 4/17/2006 Female 178 lb 10/13/2006 Physician United States
Primary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Histoplasmosis Disseminated Other Serious 7/7/2006 Female 206 lb 12/11/2006 Physician Canada
Primary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 12/19/2006 Consumer United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 12/19/2006 Consumer United States
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 1/1/2004 79 Female 12/26/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 50 Female 1/4/2007 Pharmacist Canada
Primary
Concomitant
Renal Failure Hospitalization 11/9/2005 46 Male 10/7/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/29/2005 40 Female 10/7/2006 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Death 6/24/2004 62 Male 3/27/2007 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 4/17/2006 Female 178 lb 5/4/2007 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Toothache Hospitalization 1/25/2005 41 Female 244 lb 6/12/2007 United States
Primary
Concomitant
Histoplasmosis Disseminated Other Serious 7/7/2006 Female 206 lb 6/22/2007 Physician Canada
Primary
Concomitant
Neutrophil Count Decreased 6/18/2007 Male 198 lb 7/3/2007 United States
Primary
Secondary
Concomitant
Toothache Other Serious 1/25/2005 41 Female 244 lb 7/16/2007 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 7/1/2007 Female 155 lb 8/14/2007 Consumer United States
Primary
Concomitant
Myalgia Hospitalization 6/8/2007 Female 115 lb 8/23/2007 Physician Canada
Primary
Secondary
Concomitant
Wound Treatment Hospitalization 1/25/2005 41 Female 220 lb 11/14/2007 United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 6/8/2007 Female 115 lb 12/3/2007 Physician Canada
Primary
Secondary
Concomitant
Staring Hospitalization 11/13/2007 Female 104 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 1/1/2005 Male 12/6/2007 Physician United States
Primary
Concomitant
Rash Other Serious 11/10/2006 Female 221 lb 12/6/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/20/2007 Female 168 lb 2/15/2008 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 2/15/2008 Physician United States
Primary
Concomitant
Diastolic Dysfunction Other Serious 12/1/2007 Female 2/20/2008 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 3/28/2008 Physician United States
Primary
Concomitant
Skin Injury Hospitalization 3/6/2008 49 Male 277 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 4/22/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/20/2007 Female 168 lb 5/2/2008 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Disease Other Serious 3/20/2008 60 Male 197 lb 5/15/2008 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 6/2/2008 Physician United States
Primary
Concomitant
Insomnia Disability 4/20/2007 61 Male 5/23/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/23/2002 Female 6/24/2008 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/3/2008 27 Male 88 lb 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 1/1/2007 84 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/1/2008 Female 7/2/2008 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/7/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 9/5/2008 Physician United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 11/7/2007 Female 234 lb 9/12/2008 Physician United States
Primary
Concomitant
Weight Decreased Life Threatening 1/1/2007 63 Male 241 lb 9/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 8/18/2008 Female 162 lb 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2005 72 Female 177 lb 10/29/2008 Consumer United States
Primary
Concomitant
Road Traffic Accident Other Serious 10/15/2008 41 Male 10/31/2008 Physician United States
Primary
Secondary
Concomitant
Astrocytoma Hospitalization 10/13/2008 Female 11/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 12/1/2007 Female 231 lb 12/1/2008 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 10/15/2008 41 Male 11/26/2008 Physician United States
Primary
Secondary
Concomitant
Menorrhagia 3/29/2008 Female 129 lb 12/9/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 72 Female 177 lb 12/11/2008 Consumer United States
Primary
Concomitant
Pain 10/19/2007 Female 12/15/2008 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 Female 1/5/2009 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 Female 2/13/2009 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/7/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Lymphoma Other Serious 10/1/2008 Female 325 lb 3/14/2009 United States
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 3/4/2009 23 Male 116 lb 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/9/2000 50 Female 213 lb 4/14/2009 United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 3/16/2009 Male 223 lb 4/17/2009 Canada
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 43 5/25/2009 Other Health Professional Canada
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 6/11/2009 Consumer United States
Primary
Concomitant
Nasopharyngitis 10/2/2008 Female 128 lb 6/11/2009 United States
Primary
Concomitant
Incorrect Dose Administered 2/28/2009 Female 140 lb 6/11/2009 Consumer Puerto Rico
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Salivary Gland Mass Other Serious 1/1/2008 38 Female 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vanillyl Mandelic Acid Urine Increased Death 6/12/2009 4 Male 40 lb 6/15/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/23/2003 56 Male 392 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Hepatotoxicity Other Serious 5/1/2009 24 Female 203 lb 8/6/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2009 Female 162 lb 9/4/2009 Canada
Primary
Concomitant
Injection Site Extravasation 8/23/2008 Female 130 lb 9/12/2009 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 9/21/2009 Canada
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 10/22/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2009 Female 162 lb 10/27/2009 Canada
Primary
Concomitant
Thrombocytopenia Hospitalization Male 11/4/2009 United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/3/2009 Female 210 lb 11/16/2009 Physician Canada
Primary
Concomitant
Weight Increased Other Serious 3/27/2006 Female 170 lb 11/19/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/29/2009 Female 99 lb 11/13/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/9/2000 50 Female 213 lb 11/26/2009 United States
Primary
Concomitant
Vascular Dementia Hospitalization 68 Male 11/17/2009 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/1/2009 Male 12/11/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/12/2009 Female 15 lb 12/30/2009 United States
Primary
Secondary
Concomitant
Mantle Cell Lymphoma Stage Iv Death 11/10/2009 Female 1/20/2010 Physician Canada
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 14 Male 79 lb 1/20/2010 Physician Canada
Primary
Concomitant
Sensation Of Pressure 9/1/2009 195 lb 1/29/2010 United States
Primary
Concomitant
Pulmonary Thrombosis Other Serious 1/27/2010 Male 226 lb 2/8/2010 Canada
Primary
Concomitant
Vascular Dementia Hospitalization 68 Male 2/5/2010 United States
Primary
Concomitant
Vascular Dementia Hospitalization 68 Male 2/5/2010 United States
Primary
Concomitant
Vaginal Lesion Disability 11/23/2008 61 Female 2/25/2010 Physician United States
Primary
Concomitant
Urticaria Life Threatening 1/1/2010 Male 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 4/15/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 4/19/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 4/22/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 4/29/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/6/2010 United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 4/14/2010 7 Female 57 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 5/10/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 5/7/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious Female 85 lb 5/13/2010 Canada
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 5/17/2010 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/17/2010 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 5/19/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/21/2002 59 Female 5/27/2010 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 6/8/2010 United States
Primary
Secondary
Concomitant

Drug Data