Diclofenac combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Other Serious 10/20/2005 Male 152 lb 1/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Amyotrophic Lateral Sclerosis Hospitalization 3/1/2005 46 Male 1/16/2006 Physician Spain
Primary
Secondary
Concomitant
Recurrent Cancer Hospitalization 8/22/2005 Male 1/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 9/15/2005 Male 245 lb 1/19/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 3/1/2005 46 Male 1/26/2006 Physician Spain
Primary
Secondary
Concomitant
Lumbar Spinal Stenosis Other Serious 5/19/2005 Female 119 lb 2/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Knee Arthroplasty Hospitalization 7/26/2004 Male 298 lb 2/6/2006 Germany
Primary
Concomitant
Muscle Spasms Hospitalization 1/4/2006 Male 2/7/2006 United Kingdom
Primary
Concomitant
Folliculitis Other Serious 11/2/2005 Female 293 lb 2/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Depression Other Serious 10/19/2005 24 Female 110 lb 2/10/2006 Physician Germany
Primary
Secondary
Concomitant
Peritoneal Tuberculosis Hospitalization Female 2/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Pustular Other Serious Female 142 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 151 lb 2/17/2006 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 4/13/2005 44 Male 2/21/2006 Other Health Professional Spain
Primary
Concomitant
Peritoneal Tuberculosis Hospitalization 10/17/2005 Female 185 lb 2/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious 11/1/2005 Male 192 lb 2/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Generalised Hospitalization 12/20/2005 9 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Folliculitis Other Serious 9/14/2005 Female 293 lb 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 10/3/2005 Female 110 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Tuberculosis Hospitalization 71 Female 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Function Test Decreased Hospitalization 1/1/2004 75 Male 3/11/2006 United Kingdom
Primary
Concomitant
Carcinoid Tumour Of The Caecum Other Serious 10/11/2005 Female 161 lb 3/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 2/8/2006 Male 3/24/2006 Physician Estonia
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 151 lb 3/27/2006 Physician Germany
Primary
Concomitant
False Positive Tuberculosis Test Other Serious 47 Male 205 lb 3/30/2006 Other Health Professional Germany
Primary
Concomitant
Peritoneal Tuberculosis Other Serious 10/17/2005 Female 185 lb 4/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritoneal Tuberculosis Hospitalization 10/17/2005 Female 185 lb 4/4/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Life Threatening 8/20/2004 Female 254 lb 4/6/2006 Physician Germany
Primary
Secondary
Concomitant
Gastric Ulcer Perforation Other Serious Female 185 lb 4/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/15/2005 Male 245 lb 4/11/2006 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 1/1/2001 64 Female 306 lb 4/21/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 8/1/2004 Female 5/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 3/21/2006 Female 6/26/2006 Physician Canada
Primary
Secondary
Concomitant
B-cell Lymphoma Stage Ii Other Serious 4/1/2006 68 Male 132 lb 6/28/2006 Other Health Professional Germany
Primary
Concomitant
Herpes Zoster Hospitalization 8/2/2005 58 Female 6/29/2006 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Blindness Unilateral Disability 5/2/2006 59 Female 6/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization 1/1/2005 12 Female 6/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Hospitalization 50 Female 7/14/2006 Physician Brazil
Primary
Concomitant
Lymphopenia Hospitalization 1/1/2006 33 Female 7/12/2006 Other Health Professional Austria
Primary
Concomitant
Pruritus Other Serious 50 Female 7/19/2006 Physician Brazil
Primary
Concomitant
Genital Haemorrhage Other Serious 2/18/2006 Female 130 lb 7/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Infection Other Serious Male 7/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
B-cell Lymphoma Stage Ii Other Serious 4/13/2006 68 Male 132 lb 7/31/2006 Other Health Professional Germany
Primary
Concomitant
Dysgeusia 4/1/2006 62 Female 7/12/2006 Consumer United States
Primary
Concomitant
Herpes Zoster Hospitalization 8/2/2005 58 Female 7/31/2006 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Injection Site Warmth 12/1/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Oesophageal Adenocarcinoma Hospitalization 7/9/2005 Female 196 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious 1/4/2006 Male 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 2/8/2006 Male 8/3/2006 Physician Estonia
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 2/8/2006 Male 8/3/2006 Physician Estonia
Primary
Concomitant
Bronchiectasis Hospitalization 12/16/2005 Male 150 lb 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 12/16/2005 Male 150 lb 8/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/25/2006 Female 226 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 3/15/2006 Female 143 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 3/16/2006 Female 8/15/2006 Physician United States
Primary
Concomitant
B-cell Lymphoma Other Serious 4/21/2006 Female 137 lb 8/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Bronchitis Hospitalization 9/12/2005 Female 8/18/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Other Serious 65 Female 8/14/2006 Other Health Professional Denmark
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/10/2006 Female 8/22/2006 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 7/17/2006 41 Male 8/23/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 65 Female 8/22/2006 United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 2/16/2006 Male 143 lb 8/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteoarthritis Disability 6/15/2005 Female 8/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Tuberculosis Other Serious 10/17/2005 Female 185 lb 8/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Other Serious 50 Female 9/1/2006 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/1/2006 Female 331 lb 9/7/2006 Physician United States
Primary
Concomitant
Oesophageal Adenocarcinoma Metastatic Hospitalization 7/9/2005 Female 196 lb 9/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 1/1/2004 75 Male 9/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 46 Female 9/19/2006 Physician United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 1/1/2004 75 Male 9/12/2006 United Kingdom
Primary
Concomitant
Oesophageal Carcinoma Death 8/17/2006 Male 174 lb 9/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Perforation Required Intervention 65 Female 9/14/2006 United Kingdom
Primary
Concomitant
Obstruction Other Serious 6/28/2006 Female 205 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tenosynovitis Other Serious 7/1/2005 Female 130 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 6/1/2005 66 Female 9/25/2006 United States
Primary
Secondary
Road Traffic Accident Other Serious 12/15/2005 Female 225 lb 10/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Bronchospasm Hospitalization 11/25/2005 36 Male 10/6/2006 Physician Germany
Primary
Concomitant
Emphysema Other Serious 5/15/2006 55 10/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Infection Hospitalization 9/6/2006 Female 10/13/2006 Consumer United Kingdom
Primary
Concomitant
B-cell Lymphoma Other Serious 4/21/2006 Female 137 lb 10/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/15/2006 Female 119 lb 11/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death 7/10/2006 Male 174 lb 11/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 1/1/2005 Female 107 lb 11/8/2006 Consumer Brazil
Primary
Concomitant
Neoplasm Malignant Other Serious Female 205 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Uveitis Disability 1/15/2006 Male 141 lb 11/10/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/6/2006 77 Male 11/10/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Bronchitis Hospitalization 9/12/2005 Female 11/14/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 3/27/2006 Female 194 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subcutaneous Abscess Other Serious 3/1/2006 37 Female 207 lb 3/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Generalised Other Serious 2/5/2007 52 Female 139 lb 4/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nephrolithiasis Hospitalization 2/22/2006 Female 238 lb 4/12/2007 Consumer United Kingdom
Primary
Concomitant
Pain Hospitalization 9/29/2005 Female 115 lb 4/12/2007 Consumer United Kingdom
Primary
Concomitant
Subcutaneous Abscess Other Serious 3/1/2006 37 Female 207 lb 4/7/2007 United Kingdom
Primary
Secondary
Concomitant
Juvenile Arthritis Hospitalization 8/9/2005 Female 4/19/2007 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 3/14/2007 Female 150 lb 4/25/2007 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 4/12/2006 Male 161 lb 4/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Abscess Other Serious 1/1/2006 Female 207 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 9/1/2006 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Yellow Skin Other Serious 10/1/2006 Male 154 lb 5/3/2007 Consumer Brazil
Primary
Concomitant
Vomiting Other Serious 8/25/2006 Female 139 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death Male 174 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Enterocolitis Hospitalization 10/12/2006 60 Female 5/10/2007 Physician Germany
Primary
Concomitant
Abdominal Wall Abscess Hospitalization 2/6/2007 56 Female 5/10/2007 Consumer Argentina
Primary
Secondary
Concomitant
Vasculitis Hospitalization Female 173 lb 5/18/2007 Physician United Kingdom
Primary
Concomitant
Vitritis Hospitalization 3/15/2007 Female 123 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Abscess Limb Hospitalization 5/9/2007 65 Female 150 lb 5/25/2007 Physician Saudi Arabia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 81 Female 5/26/2007 Other Health Professional
Primary
Secondary
Cholecystitis Hospitalization 2/5/2007 54 Female 5/30/2007 Consumer Poland
Primary
Concomitant
Abortion Spontaneous Other Serious 12/16/2006 Female 119 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Carcinoma In Situ Other Serious 11/15/2005 Female 128 lb 5/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 65 Female 6/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vitritis Other Serious 3/13/2007 Female 101 lb 6/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Hospitalization Female 173 lb 6/12/2007 Physician United Kingdom
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 1/1/2007 Female 6/13/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 81 Female 6/13/2007 Other Health Professional
Primary
Secondary
Gout Hospitalization 12/16/2006 Male 209 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2005 Female 269 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2007 Male 262 lb 6/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hyperventilation Female 6/22/2007 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/19/2006 25 Female 132 lb 7/2/2007 Pharmacist United Kingdom
Primary
Concomitant
Hypoglycaemia Life Threatening 4/1/2007 60 Female 220 lb 7/6/2007 Physician Netherlands
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 12/9/2004 Female 143 lb 7/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 10/1/2006 Female 7/13/2007 Physician Canada
Primary
Secondary
Concomitant
Hernial Eventration Hospitalization 7/12/2007 56 Female 7/19/2007 Other Health Professional Argentina
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 12/7/2006 Male 165 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Colic Other Serious 11/5/2006 Male 176 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bursitis Hospitalization 7/20/2006 Female 198 lb 8/10/2007 United Kingdom
Primary
Concomitant
Lacunar Infarction Other Serious 12/30/2005 Female 166 lb 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 7/27/2007 55 Female 8/13/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 14 Male 8/13/2007 United Kingdom
Primary
Secondary
Swelling Face Other Serious 10/16/2006 Female 141 lb 8/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Viral Infection Hospitalization 7/16/2007 45 Male 163 lb 8/17/2007 Physician Argentina
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 4/10/2007 Male 198 lb 8/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
B-cell Lymphoma Other Serious 4/21/2006 Female 137 lb 8/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 11/21/2006 Male 8/21/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 7/20/2007 57 Female 8/21/2007 Consumer Thailand
Primary
Concomitant
Appendiceal Abscess Hospitalization 8/1/2007 50 Female 8/30/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 7/27/2007 55 Female 9/4/2007 Physician Japan
Primary
Concomitant
Gastric Ulcer Death 8/1/2007 Male 205 lb 9/4/2007 Physician Poland
Primary
Concomitant
Spinal Fusion Surgery Other Serious 4/1/2007 Female 132 lb 9/7/2007 Canada
Primary
Concomitant
Joint Swelling Disability 7/23/2007 70 Female 77 lb 9/11/2007 Physician United Kingdom
Primary
Concomitant
Appendiceal Abscess Hospitalization 8/1/2007 50 Female 9/13/2007 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization Female 191 lb 9/14/2007 Canada
Primary
Concomitant
Rash Generalised Hospitalization 9/7/2007 Female 9/18/2007 Physician Singapore
Primary
Concomitant
Typhoid Fever Hospitalization 5/1/2007 Male 9/20/2007 Germany
Primary
Concomitant
Atrial Flutter Hospitalization 8/22/2007 65 Male 9/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Death 81 Female 9/24/2007
Primary
Secondary
Anaemia Hospitalization 8/29/2007 47 Female 119 lb 9/20/2007 Physician United States
Primary
Concomitant
Anaemia Hospitalization 8/29/2007 47 Female 119 lb 9/28/2007 Physician United States
Primary
Concomitant

Drug Data