Methotrexate combined with Tylenol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Cancer Other Serious 1/1/2005 Female 154 lb 1/3/2006 Physician United States
Primary
Concomitant
Myalgia Hospitalization 1/1/2005 Female 1/6/2006 Physician United States
Primary
Concomitant
Ischaemic Stroke Other Serious 5/1/2002 48 Male 190 lb 1/10/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/15/2000 45 Male 194 lb 1/10/2006 Physician United States
Primary
Concomitant
Suicide Attempt Hospitalization 11/16/2002 17 Female 125 lb 2/7/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Cavitation Other Serious 6/5/2003 Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Peritonitis Other Serious 12/1/1998 Female 110 lb 2/17/2006 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 2/1/2003 73 Female 110 lb 2/22/2006 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/11/2006 Male 3/28/2006 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 9/1/2005 Female 3/28/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2003 72 Male 143 lb 5/10/2006 Lawyer United States
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 6/30/2006 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 7/31/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/24/2002 Female 8/1/2006 Physician United States
Primary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 6/1/2006 Female 154 lb 8/28/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2004 Female 9/6/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious Male 9/8/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 1/1/2004 Female 9/8/2006 Physician United States
Primary
Concomitant
Postoperative Infection Other Serious 1/1/2003 Male 310 lb 9/14/2006 Physician United States
Primary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 9/15/2006 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 5/29/2006 Female 142 lb 9/20/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/21/2006 Female 139 lb 9/22/2006 Physician Canada
Primary
Concomitant
Respiratory Tract Carcinoma In Situ Death Male 212 lb 9/26/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 7/7/2004 Female 146 lb 9/26/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 5/18/2004 Female 155 lb 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/17/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Uterine Cancer Other Serious 4/1/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Death Other Serious Female 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Other Serious 9/7/2004 Female 159 lb 10/4/2006 Consumer United States
Primary
Concomitant
B-cell Lymphoma Other Serious 5/18/2004 Female 143 lb 10/16/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Female 134 lb 10/16/2006 Physician United States
Primary
Concomitant
T-cell Lymphoma Other Serious 8/23/2003 Female 157 lb 10/16/2006 Physician United States
Primary
Concomitant
Mesenteric Vascular Insufficiency Other Serious 5/14/2002 Female 215 lb 10/16/2006 Physician United States
Primary
Concomitant
Toe Deformity Other Serious 1/1/2003 Female 11/10/2006 Physician Canada
Primary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/21/2006 Female 139 lb 11/30/2006 Physician Canada
Primary
Concomitant
Cholecystectomy Hospitalization 5/1/2006 Male 12/8/2006 Physician United States
Primary
Concomitant
Gastroenteritis Hospitalization 6/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Carotid Endarterectomy Hospitalization 1/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 12/11/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Nerve Injury 7/15/2006 Female 180 lb 12/18/2006 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 9/30/2006 Female 166 lb 12/22/2006 Physician United States
Primary
Concomitant
Pseudomyxoma Peritonei Other Serious 5/30/2006 Male 12/22/2006 Physician United States
Primary
Concomitant
Muscle Spasms 9/1/2006 78 Female 159 lb 12/22/2006 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 6/1/2006 Male 12/29/2006 Physician United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 8/1/2006 69 Male 226 lb 1/11/2007 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious 7/1/2006 Female 207 lb 2/20/2007 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 8/31/2006 Female 105 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 2/1/2006 Female 170 lb 2/28/2007 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious 7/1/2006 Male 3/1/2007 Physician United States
Primary
Concomitant
Breast Cancer Hospitalization Female 3/1/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 3/20/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Spinal Column Stenosis Hospitalization 8/1/2006 69 Male 226 lb 3/13/2007 Physician United States
Primary
Concomitant
Perforated Ulcer Hospitalization 9/1/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 10/1/2006 Male 3/27/2007 Physician United States
Primary
Concomitant
Anosmia 12/1/2006 84 Male 3/27/2007 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Life Threatening 12/13/2006 68 Female 3/27/2007 Consumer United States
Primary
Concomitant
Temporal Lobe Epilepsy Hospitalization 8/30/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 53 Female 4/5/2007 Lawyer United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 10/2/2006 Male 4/13/2007 Physician United States
Primary
Concomitant
Nervous System Disorder Other Serious 1/1/2007 Female 150 lb 4/13/2007 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/1998 Female 4/17/2007 Physician United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 2/22/2007 62 Male 4/18/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 11/1/2006 Female 4/25/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/20/2007 Female 4/30/2007 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2006 Female 116 lb 5/2/2007 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 11/23/2006 Female 190 lb 5/7/2007 Consumer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/8/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/10/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2007 Female 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Optic Ischaemic Neuropathy Other Serious 11/1/2004 Male 175 lb 5/16/2007 Lawyer United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/12/2005 50 Female 141 lb 5/23/2007 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2000 21 Female 5/24/2007 Consumer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/25/2007 Physician United States
Primary
Concomitant
Tremor 11/30/2006 54 Female 3/13/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/1/2007 Female 140 lb 6/11/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2006 74 Female 6/13/2007 Physician United States
Primary
Concomitant
Toe Deformity Other Serious 1/1/2003 Female 6/22/2007 Physician Canada
Primary
Concomitant
Necrotising Fasciitis Hospitalization 4/28/2007 Female 117 lb 6/27/2007 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 6/29/2007 Physician United States
Primary
Concomitant
Temperature Intolerance Other Serious 10/1/2006 Female 159 lb 8/20/2007 Other Health Professional Canada
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 10/11/2007 54 Female 11/14/2007
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 7/24/2007 79 Male 11/16/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 5/1/2007 Female 256 lb 11/21/2007 Physician United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 7/1/2005 Female 181 lb 12/3/2007 Physician United States
Primary
Concomitant
Osteopenia Other Serious 1/1/2002 Female 116 lb 12/6/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 9/25/2006 Female 12/10/2007 Physician United States
Primary
Concomitant
Nausea 1/1/2006 Female 12/10/2007 Physician United States
Primary
Concomitant
Joint Stiffness 2/1/2007 Female 12/13/2007 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 11/25/2007 1 Male 23 lb 12/10/2007 Pharmacist United States
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 8/1/2007 1 Male 22 lb 12/11/2007 Physician United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 7/1/2005 Female 181 lb 12/18/2007 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 12/18/2007 Physician United States
Primary
Concomitant
Weaning Failure Hospitalization 3/19/2007 1 Male 12 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
Throat Irritation 69 Female 150 lb 12/21/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 9/1/2007 58 Female 12/21/2007 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2006 75 Female 128 lb 1/7/2008 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2007 Female 1/7/2008 United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2007 Female 1/8/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/25/2008 Physician United States
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Other Serious 2/28/2008 Male 210 lb 4/28/2008 Physician United States
Primary
Concomitant
Raynaud's Phenomenon Other Serious 1/1/1999 66 Female 126 lb 4/29/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/13/2007 3 Female 37 lb 5/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Other Serious 2/28/2008 Male 210 lb 5/12/2008 Physician United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2007 Female 306 lb 5/22/2008 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 5/12/2008 82 Female 5/23/2008 Consumer United States
Primary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 6/5/2008 Physician United States
Primary
Concomitant
Pharyngeal Mass 6/5/2008 Female 127 lb 6/11/2008 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 2/24/2008 79 Female 168 lb 5/21/2008 Pharmacist United States
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Gingival Bleeding 10/1/2007 Female 132 lb 6/23/2008 Physician United States
Primary
Concomitant
Viral Infection Life Threatening 6/1/2008 Female 145 lb 6/18/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 6/25/2008 Physician United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 11/9/2007 69 Female 6/30/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Swelling 2/20/2008 Female 7/8/2008 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 7/16/2008 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 7/3/2002 Female 7/17/2008 Other Health Professional United States
Primary
Concomitant
Wisdom Teeth Removal Other Serious 7/1/2005 Female 7/17/2008 Physician United States
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 6/14/2008 68 Female 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 5/12/2008 82 Female 7/28/2008 Consumer United States
Primary
Concomitant
Smear Cervix Abnormal Other Serious 10/1/2007 Female 145 lb 8/1/2008 Physician Canada
Primary
Concomitant
Wisdom Teeth Removal Other Serious 7/1/2005 Female 8/4/2008 Physician United States
Primary
Secondary
Concomitant
Optic Neuritis Other Serious 1/1/2007 64 Female 8/13/2008 Physician United States
Primary
Concomitant
Deafness Neurosensory Disability 6/14/2008 68 Female 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 7/31/2008 37 Female 8/15/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/8/2008 71 Male 8/15/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Tremor Other Serious 1/1/2008 Female 10/24/2008 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Visual Impairment Other Serious 4/21/2008 Male 36 lb 11/4/2008 Pharmacist Brazil
Primary
Concomitant
Euphoric Mood Other Serious 10/1/2008 Male 90 lb 11/6/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 166 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Pneumonia Legionella Hospitalization 10/1/2008 Female 11/7/2008 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 2/27/2007 Female 71 lb 11/12/2008 Physician United States
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 10/7/2008 Female 133 lb 11/14/2008 Other Health Professional Canada
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2007 Female 1/29/2009 Physician United States
Primary
Concomitant
Raynaud's Phenomenon Other Serious 1/1/1999 66 Female 126 lb 2/5/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Euphoric Mood Other Serious 10/1/2008 Male 90 lb 2/9/2009 Physician United States
Primary
Concomitant

Drug Data