Methotrexate combined with Takepron

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Tuberculosis Hospitalization 6/12/2005 Female 112 lb 1/6/2006 Physician Japan
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 8/23/2005 Female 2/6/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 10/7/2004 Female 112 lb 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 6/22/2005 Female 4/3/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/24/2006 65 Male 134 lb 4/11/2006 Physician Japan
Primary
Concomitant
Urticaria Other Serious 11/27/2003 Female 95 lb 4/20/2006 Physician Japan
Primary
Concomitant
Anaphylactic Reaction Hospitalization 4/4/2006 Male 134 lb 5/25/2006 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/12/2005 Female 112 lb 6/12/2006 Physician Japan
Primary
Concomitant
Stenotrophomonas Infection Hospitalization 9/30/2006 Female 154 lb 12/21/2006 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/12/2005 Female 112 lb 2/7/2007 Physician Japan
Primary
Concomitant
Arthritis Bacterial Hospitalization 2/16/2007 Female 104 lb 4/17/2007 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 10/22/2003 Male 110 lb 5/25/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 10/17/2003 Female 97 lb 6/15/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/27/2006 30 Female 90 lb 7/3/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/27/2006 30 Female 90 lb 7/3/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/27/2006 30 Female 90 lb 7/12/2007 Japan
Primary
Secondary
Concomitant
Rash Other Serious 9/24/2007 Female 112 lb 11/9/2007 Physician Japan
Primary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 11/12/2007 Physician Japan
Primary
Concomitant
Oesophageal Carcinoma Other Serious 4/3/2007 Male 148 lb 11/13/2007 Physician Japan
Primary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 11/29/2007 Physician Japan
Primary
Concomitant
Aortic Dissection Death 5/11/2006 Female 110 lb 12/26/2007 Physician Japan
Primary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 1/31/2008 Physician Japan
Primary
Concomitant
Nausea Other Serious 9/26/2007 59 Male 121 lb 2/6/2008 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 1/4/2008 Female 4/1/2008 Physician Japan
Primary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 3/18/2008 Female 79 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 8/1/2006 Female 110 lb 5/30/2008 Physician Japan
Primary
Concomitant
Central Nervous System Lymphoma Other Serious 2/1/2006 Female 117 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 3/18/2008 Female 79 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 4/12/2008 Female 101 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Aortic Dissection Death 5/11/2006 Female 110 lb 7/1/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hodgkin's Disease Hospitalization 8/12/2004 Male 123 lb 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/16/2006 Female 121 lb 7/8/2008 Japan
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 8/1/2006 Female 110 lb 7/9/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 2/1/2006 Female 117 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/22/2008 23 Female 137 lb 12/1/2008 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Other Serious 65 Male 12/10/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/4/2008 1/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 1/9/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/2/2008 Male 2/9/2009 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/15/2008 Male 3/6/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 3/20/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/4/2008 3/20/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/4/2008 4/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/21/2008 56 Male 132 lb 4/15/2009 Physician Japan
Primary
Concomitant
Hodgkin's Disease Other Serious 9/4/2006 Female 126 lb 4/16/2009 Physician Japan
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/9/2009 Female 88 lb 4/17/2009 Physician Japan
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/9/2009 Female 88 lb 5/1/2009 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 10/20/2008 Male 154 lb 5/14/2009 Physician Japan
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/9/2009 Female 88 lb 5/27/2009 Physician Japan
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/9/2009 Female 88 lb 5/29/2009 Physician Japan
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/9/2009 Female 88 lb 6/23/2009 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 10/20/2008 Male 154 lb 6/29/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Death 3/12/2008 Male 126 lb 7/31/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 6/9/2008 62 Male 154 lb 9/1/2009 Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/11/2008 56 Male 132 lb 9/24/2009 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 6/4/2008 62 Male 154 lb 10/7/2009 Physician Japan
Primary
Secondary
Concomitant
Thyroid Cancer Hospitalization 1/1/2007 Female 10/14/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 6/4/2008 62 Male 154 lb 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 11/16/2009 Female 1/21/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/21/2009 Female 2/1/2010 Physician Japan
Primary
Concomitant
Lymphoma Hospitalization 9/22/2009 Female 99 lb 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/21/2009 Male 139 lb 2/22/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 3/1/2009 Female 143 lb 2/23/2010 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 10/16/2009 Female 2/25/2010 Other Health Professional Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 10/2/2008 28 Female 112 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Death 3/12/2008 Male 126 lb 3/9/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 5/14/2009 Female 95 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 9/8/2009 Female 99 lb 3/14/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/17/2009 57 Male 108 lb 4/12/2010 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 2/12/2010 79 Female 4/16/2010 Japan
Primary
Concomitant
Bladder Cancer Hospitalization 7/30/2009 83 Male 110 lb 5/17/2010 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 2/12/2010 79 Female 5/20/2010 Japan
Primary
Concomitant
Hypercholesterolaemia Other Serious 11/10/2009 56 Female 5/27/2010 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 8/11/2009 62 Female 110 lb 6/8/2010 Physician Japan
Primary
Concomitant
Actinomycosis Hospitalization 6/1/2009 60 Female 146 lb 6/11/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 4/1/2010 85 Male 131 lb 6/25/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/17/2009 57 Male 108 lb 6/30/2010 Physician Japan
Primary
Concomitant
Pemphigoid Other Serious 6/13/2010 63 Female 7/14/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Life Threatening 1/1/2010 65 Female 106 lb 7/20/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 8/2/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 6/26/2006 54 Female 115 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Device Related Infection Hospitalization 2/21/2009 82 Male 143 lb 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 11/24/2006 51 Male 115 lb 8/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Life Threatening 4/8/2010 67 Male 121 lb 8/17/2010 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 9/2/2008 47 Male 8/17/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 11/24/2006 51 Male 115 lb 8/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/18/2008 31 Female 8/27/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 9/2/2008 47 Male 8/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Life Threatening 4/8/2010 67 Male 121 lb 9/7/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 3/1/2009 47 Female 143 lb 9/13/2010 Physician Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Iv Other Serious 8/31/2009 73 Female 157 lb 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 9/23/2010 Physician Japan
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 9/18/2008 31 Female 9/27/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/11/2009 62 Female 110 lb 10/4/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 9/18/2008 31 Female 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 6/26/2006 54 Female 115 lb 10/12/2010 Physician Japan
Primary
Secondary
Concomitant
Pemphigoid Other Serious 6/16/2010 63 Female 10/19/2010 Physician Japan
Primary
Concomitant
Pemphigoid Other Serious 6/16/2010 63 Female 11/1/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 11/2/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 9/18/2008 31 Female 11/9/2010 Physician Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Iv Other Serious 8/31/2009 73 Female 157 lb 11/9/2010 Physician Japan
Primary
Secondary
Concomitant
Erysipelas Hospitalization 9/30/2010 39 Female 103 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2010 11/11/2010 Physician Japan
Primary
Concomitant
Encephalitis Fungal Death Male 139 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 9/8/2009 39 Female 99 lb 11/16/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/1/2008 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Memory Impairment Hospitalization 8/25/2010 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Palpitations Other Serious 5/1/2010 42 Female 154 lb 12/17/2010 Other Health Professional Japan
Primary
Concomitant
Viral Infection Hospitalization 12/5/2010 60 Female 134 lb 12/17/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 12/5/2010 60 Female 134 lb 1/21/2011 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 3/31/2009 83 Female 110 lb 2/3/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/12/2010 36 Male 212 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 7/25/2010 60 Female 93 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 9/22/2009 62 Female 99 lb 2/23/2011 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 2/12/2010 79 Female 3/3/2011 Physician Japan
Primary
Concomitant
Abscess Jaw Hospitalization 12/7/2010 55 Female 97 lb 3/4/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Life Threatening 1/24/2005 50 Male 121 lb 3/11/2011 Physician Japan
Primary
Secondary
Concomitant
Atrophic Glossitis Other Serious 2/23/2011 31 Female 104 lb 3/14/2011 Physician Japan
Primary
Concomitant
Abscess Jaw Hospitalization 12/7/2010 55 Female 97 lb 3/18/2011 Physician Japan
Primary
Concomitant
Herpes Zoster Other Serious 9/9/2009 36 Female 125 lb 3/31/2011 Physician Japan
Primary
Concomitant
Blood Urea Increased Hospitalization 1/24/2005 50 Male 121 lb 4/7/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Hospitalization 9/9/2009 36 Female 125 lb 4/7/2011 Physician Japan
Primary
Concomitant
Pseudomonas Infection Hospitalization 8/4/2006 48 Male 165 lb 4/12/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Death 2/14/2011 62 Female 110 lb 4/8/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 1/3/2011 79 Female 143 lb 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Disseminated Tuberculosis Hospitalization 2/2/2011 86 Female 93 lb 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Melaena Other Serious 10/18/2009 48 Female 97 lb 4/15/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 7/25/2010 60 Female 93 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Glucose Tolerance Impaired Disability 6/5/2009 59 Male 146 lb 4/22/2011 Physician Japan
Primary
Secondary
Concomitant
Influenza Life Threatening 2/14/2011 62 Female 110 lb 4/22/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/10/2007 40 Male 126 lb 4/29/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/20/2008 58 Male 119 lb 4/29/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/2/2007 56 Female 95 lb 5/2/2011 Physician Japan
Primary
Secondary
Concomitant
Systemic Candida Death 4/24/2009 38 Male 157 lb 5/5/2011 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Death 12/2008 Male 169 lb 11/14/2012 Physician Jp
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/11/2011 Male 9/4/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 12/5/2011 72 Female 123 lb 12/10/2012 Physician Jp
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/1/2012 79 Female 88 lb 9/18/2012 Physician Jp
Primary
Concomitant
Septic Shock Hospitalization 7/15/2012 50 Female 105 lb 9/4/2012 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/18/2012 82 Female 117 lb 9/27/2012 Physician Jp
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/6/2012 57 Female 11/14/2012 Physician Jp
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 9/27/2011 58 Female 10/12/2012 Physician Jp
Primary
Secondary
Concomitant
Swelling Face Hospitalization 2012 Female 132 lb 9/28/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Shock Death 8/2012 29 Female 119 lb 11/26/2012 Pharmacist Jp
Primary
Secondary
Concomitant
Colitis Ulcerative Other Serious 9/4/2012 21 Female 108 lb 11/19/2012 Consumer Jp
Primary
Secondary
Concomitant
Liver Disorder Other Serious 6/26/2012 65 Female 101 lb 12/5/2012 Physician Jp
Primary
Concomitant

Drug Data