Effexor combined with Methotrexate

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dystonia Other Serious 8/14/2005 36 Female 184 lb 1/18/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/4/2005 48 Female 1/17/2005 Australia
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 6/1/2005 Female 1/27/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/2/2006 Female 168 lb 2/10/2006 Consumer United States
Primary
Concomitant
Vascular Dementia Hospitalization 1/1/2000 74 Male 99 lb 2/23/2006 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Death Female 3/1/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2002 47 Female 240 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Respiratory Failure Death 1/1/2003 Female 3/31/2006 Other Health Professional Canada
Primary
Concomitant
Knee Arthroplasty Other Serious Male 225 lb 3/23/2006 United States
Primary
Concomitant
Meningitis Viral Other Serious 3/24/2006 Female 215 lb 4/5/2006 Consumer United States
Primary
Concomitant
Urticaria Hospitalization 8/30/2001 47 Male 187 lb 4/6/2006 Physician United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2002 Female 104 lb 4/12/2006 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/13/2003 56 Female 181 lb 4/14/2006 Lawyer United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 11/1/2005 Male 4/14/2006 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death 8/20/2001 63 Female 198 lb 4/26/2006 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2002 49 Female 236 lb 5/9/2006 Physician United States
Primary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/10/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/16/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/17/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/19/2006 Physician Australia
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Male 6/9/2006 Physician United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2002 Female 104 lb 6/13/2006 Physician United States
Primary
Secondary
Concomitant
Vitamin B12 Decreased Hospitalization 4/1/2006 56 Female 193 lb 6/20/2006 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 6/30/2006 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 4/1/2006 56 Female 193 lb 7/20/2006 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 7/31/2006 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2002 Female 104 lb 8/2/2006 Physician United States
Primary
Secondary
Concomitant
Vitamin B12 Decreased Hospitalization 4/1/2006 56 Female 193 lb 8/8/2006 Physician United States
Primary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Synovial Rupture Hospitalization 4/20/2006 71 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Synovial Rupture Hospitalization 4/20/2006 71 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 9/15/2006 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis Other Serious 3/1/2006 Female 9/19/2006 Consumer United States
Primary
Concomitant
Death Other Serious Female 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 4/1/2006 Female 10/13/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 9/11/2006 Female 10/13/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 19 Female 10/24/2006 Physician United States
Primary
Concomitant
Laryngeal Cancer Other Serious 9/1/2006 Male 145 lb 11/2/2006 Other Health Professional Canada
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 4/1/2006 Female 11/3/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 9/11/2006 Female 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 11/6/2006 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 11/21/2005 32 Female 11/17/2006 Other Health Professional Sweden
Primary
Concomitant
Skin Cancer Other Serious 4/1/2006 Female 123 lb 12/7/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 1/1/2004 16 Female 11/29/2006 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 12/6/2005 Male 208 lb 12/13/2006 Physician United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 1/1/2006 Female 144 lb 12/13/2006 Physician United States
Primary
Concomitant
Arthralgia 4/21/2006 Female 12/13/2006 Consumer United States
Primary
Concomitant
Injection Site Pain 10/25/2006 Female 12/14/2006 Consumer United States
Primary
Concomitant
Muscular Weakness 8/21/2006 36 Female 198 lb 12/22/2006 Consumer United States
Primary
Concomitant
Tendon Rupture Hospitalization 6/9/2006 Female 179 lb 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 6/28/2005 59 Female 190 lb 1/9/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/25/2005 54 Male 11/6/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 6/28/2005 59 Female 190 lb 2/1/2007 Consumer United States
Primary
Concomitant
Medical Device Complication Hospitalization 3/19/2007 27 Female 4/23/2007 Consumer United States
Primary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 5/3/2007 Physician United States
Primary
Concomitant
Optic Ischaemic Neuropathy Other Serious 11/1/2004 Male 175 lb 5/16/2007 Lawyer United States
Primary
Concomitant
Respiratory Disorder Other Serious 9/12/2006 Male 145 lb 6/8/2007 Other Health Professional Canada
Primary
Concomitant
Small Cell Lung Cancer Metastatic Other Serious 1/1/2004 Female 205 lb 8/13/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 7/6/2007 Female 8/14/2007 Other Health Professional United States
Primary
Concomitant
Lung Cancer Metastatic Life Threatening 7/1/2007 Female 231 lb 8/16/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2005 Male 154 lb 9/17/2007 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2006 55 Female 175 lb 9/14/2007 Physician United States
Primary
Concomitant
Pelvic Pain 7/27/2007 63 Female 159 lb 9/26/2007 Consumer United States
Primary
Concomitant
Insomnia 9/9/2007 51 Male 177 lb 10/5/2007 Consumer United States
Primary
Secondary
Concomitant
Injection Site Reaction Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 5/15/2006 Female 200 lb 12/6/2007 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2006 Female 12/6/2007 Physician United States
Primary
Concomitant
Urticaria 12/13/2006 Female 12/8/2007 Other Health Professional United States
Primary
Concomitant
Injection Site Reaction 7/1/2007 Female 12/13/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 8/22/2007 68 Female 201 lb 12/21/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 Female 224 lb 2/13/2008 Consumer United States
Primary
Concomitant
Diastolic Dysfunction Other Serious 12/1/2007 Female 2/20/2008 Physician United States
Primary
Concomitant
Soft Tissue Disorder Required Intervention 3/1/2003 63 Female 1/17/2008 United States
Primary
Concomitant
Influenza Hospitalization 2/18/2008 Female 194 lb 2/28/2008 Consumer United States
Primary
Concomitant
Tooth Abscess Other Serious 8/24/2007 56 Female 3/17/2008 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/18/2008 74 Female 112 lb 3/18/2008 Physician
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/18/2008 74 Female 3/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Death 1/19/2008 49 Male 154 lb 3/29/2008 Physician France
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 3/8/2008 48 Male 248 lb 3/28/2008 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 1/1/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Raynaud's Phenomenon 2/1/2006 54 Female 4/3/2007 Physician United States
Primary
Concomitant
Progesterone Receptor Assay Positive Other Serious 10/8/2007 58 Female 4/25/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/1/2008 28 Male 123 lb 5/6/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/3/2008 63 Male 5/6/2008 Consumer Canada
Primary
Concomitant
Rash Hospitalization 11/15/2007 Male 220 lb 5/22/2008 Physician United Kingdom
Primary
Concomitant
Breast Cancer Female Other Serious 10/8/2007 58 Female 5/19/2008 Consumer United States
Primary
Concomitant
Rash Hospitalization 5/6/2007 Male 220 lb 5/30/2008 Physician Germany
Primary
Secondary
Concomitant
Mental Disorder Hospitalization Female 6/2/2008 Consumer United States
Primary
Concomitant
Influenza Like Illness Other Serious 9/1/2006 62 Female 220 lb 6/27/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/1/2008 28 Male 123 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 10/19/2006 Male 196 lb 7/18/2008 Canada
Primary
Concomitant
Influenza Like Illness Other Serious 9/1/2006 62 Female 220 lb 7/15/2008 United States
Primary
Concomitant
Vertigo Other Serious 7/17/2002 54 Male 7/30/2008 Physician United Kingdom
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2006 62 Female 220 lb 7/24/2008 United States
Primary
Concomitant
Abdominal Discomfort Other Serious 7/19/2008 Female 253 lb 8/25/2008 Physician United States
Primary
Concomitant
Fungal Infection 3/10/2008 56 Female 9/25/2008 Consumer United States
Primary
Concomitant
Pancreatic Cyst Other Serious 65 Female 125 lb 10/13/2008 Physician United States
Primary
Concomitant
Pancreatic Cyst Other Serious 65 Female 125 lb 10/13/2008 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 1/1/2008 49 Female 10/30/2008 Other Health Professional Switzerland
Primary
Concomitant
Gastrointestinal Obstruction Other Serious 7/19/2008 Female 253 lb 10/30/2008 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 61 Female 10/30/2008 Physician United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 11/27/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/1/2007 Female 12/8/2008 Other Health Professional United States
Primary
Concomitant
Rash 12/28/2007 Female 132 lb 12/10/2008 Physician United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/21/2005 61 Female 12/8/2008 Physician United States
Primary
Concomitant
Cellulitis 9/8/2008 Male 350 lb 12/17/2008 Physician United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 12/19/2008 Physician United States
Primary
Concomitant
Ear Operation Other Serious 12/1/2008 Female 238 lb 12/23/2008 Other Health Professional Canada
Primary
Concomitant
Venous Thrombosis Limb Other Serious 9/28/2004 61 Female 12/18/2008 Physician United States
Primary
Concomitant
Joint Arthroplasty Other Serious 12/8/2008 Female 214 lb 1/2/2009 Canada
Primary
Concomitant
Nerve Compression Other Serious 12/15/2008 78 Female 1/21/2009 Consumer Australia
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/20/2009 Physician United States
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 2/3/2009 Female 170 lb 2/20/2009 Other Health Professional Canada
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 2/23/2009 Physician United States
Primary
Concomitant
Ileostomy Hospitalization Male 2/26/2009 Physician United Kingdom
Primary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 170 lb 3/2/2009 Other Health Professional Canada
Primary
Concomitant
Crohn's Disease Hospitalization 11/8/2008 Female 106 lb 3/14/2009 United States
Primary
Concomitant
Hypophagia 11/11/2008 Male 190 lb 3/14/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting 11/1/2008 Female 155 lb 3/14/2009 Consumer United States
Primary
Concomitant
Lower Limb Fracture Other Serious 11/25/2008 Female 116 lb 3/16/2009 Canada
Primary
Concomitant
Crohn's Disease Hospitalization 1/13/2009 Male 155 lb 3/19/2009 Canada
Primary
Concomitant
Breast Cancer Female Other Serious 9/20/2008 65 Female 4/3/2009 Consumer Australia
Primary
Concomitant
Deafness Other Serious 11/1/2008 4/6/2009 Other Health Professional France
Primary
Concomitant
Nausea 1/28/2009 41 Female 4/2/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2008 27 Male 123 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2008 27 Male 123 lb 4/21/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/1/2008 Female 160 lb 4/22/2009 Canada
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2009 Female 191 lb 4/27/2009 Other Health Professional United States
Primary
Concomitant
Night Sweats Hospitalization 1/1/2009 Female 4/29/2009 Other Health Professional France
Primary
Concomitant
Arrhythmia Death 3/28/2009 Male 248 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting 1/2/2009 51 Female 148 lb 5/18/2009 Consumer United States
Primary
Concomitant
Pyrexia 11/10/2008 Female 6/11/2009 United States
Primary
Concomitant
Muscle Strain 1/1/2009 Male 180 lb 6/12/2009 Physician United States
Primary
Concomitant
Drug Dose Omission 5/4/2009 Female 300 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/16/2006 59 Female 140 lb 6/16/2009 United States
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Rash Hospitalization 1/11/2009 Male 128 lb 7/20/2009 Canada
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2008 Female 170 lb 7/21/2009 Consumer United States
Primary
Concomitant
Ear Operation Other Serious 12/1/2008 Female 238 lb 7/23/2009 Other Health Professional Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/23/2003 56 Male 392 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2008 Female 170 lb 8/10/2009 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 7/5/2009 Female 251 lb 8/21/2009 Other Health Professional Canada
Primary
Concomitant
Tinnitus Other Serious 1/1/2007 47 Female 9/2/2009 Other Health Professional Finland
Primary
Concomitant
Colon Cancer Other Serious 10/10/2008 Female 130 lb 9/4/2009 Physician United States
Primary
Concomitant
Pain Other Serious 7/1/2009 Female 150 lb 9/10/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 7/16/2009 Male 185 lb 9/19/2009 Consumer United States
Primary
Concomitant