Methotrexate combined with Naproxen

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Hospitalization 12/24/2005 42 Female 1/6/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Hepatomegaly Hospitalization 3/23/2005 46 Female 1/12/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Death Death 12/25/2005 57 Male 235 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Varicella Hospitalization 12/7/2005 11 Male 1/13/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/24/2005 42 Female 1/18/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 1/25/2006 Physician Belgium
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/10/2005 Female 1/26/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/10/2005 Female 1/27/2006 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/25/2003 78 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/24/2005 42 Female 2/2/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 2/3/2006 Physician Belgium
Primary
Secondary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 Male 203 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 2/2/2005 Female 159 lb 2/10/2006 United Kingdom
Primary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 Male 2/17/2006 Consumer Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2000 53 Female 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Renal Failure Death 12/25/2005 57 Male 235 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 12/15/2005 66 Male 2/14/2006 Sweden
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 1/28/2006 Male 249 lb 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Varicella Hospitalization 12/7/2005 11 Male 2/28/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 9 Female 3/7/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 3/7/2006 Consumer Canada
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 3/13/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 66 Male 201 lb 3/14/2006 Lawyer United States
Primary
Concomitant
Varicella Hospitalization 12/7/2005 11 Male 3/16/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Injection Site Cellulitis Other Serious 2/25/2006 Male 311 lb 3/16/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 2/10/2006 50 Male 143 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Tuberculosis Hospitalization 1/1/2005 Male 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 3/27/2006 Physician Canada
Primary
Concomitant
Uveitis Hospitalization 11/16/2000 Female 4/4/2006 Other Health Professional Germany
Primary
Concomitant
Oesophagitis Hospitalization 1/1/2002 Male 4/4/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 1/28/2006 Male 249 lb 4/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 66 Male 201 lb 4/6/2006 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/13/2003 56 Female 181 lb 4/14/2006 Lawyer United States
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Dysphagia Hospitalization 11/1/2005 Female 142 lb 4/20/2006 Consumer United States
Primary
Concomitant
Sigmoiditis Hospitalization 3/27/2006 70 Male 146 lb 4/20/2006 Physician France
Primary
Secondary
Concomitant
Abscess Hospitalization 11 Female 5/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 5/1/2006 Physician Brazil
Primary
Concomitant
Polyneuropathy Hospitalization 4/12/2006 46 Female 5/4/2006 Other Health Professional Mexico
Primary
Secondary
Concomitant
Tonsillitis Other Serious 11/2/2005 Female 119 lb 5/5/2006 Netherlands
Primary
Concomitant
Tonsillitis Other Serious 11/2/2005 Female 119 lb 5/12/2006 Netherlands
Primary
Concomitant
Breast Cancer Hospitalization 8/1/2005 71 Female 201 lb 1/5/2006 Physician United States
Primary
Concomitant
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 5/23/2006 Other Health Professional France
Primary
Secondary
Tenderness Hospitalization 11 Female 5/15/2006 United States
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 5/26/2006 Physician France
Primary
Secondary
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 5/26/2006 Consumer France
Primary
Secondary
Tonsillitis Other Serious 11/2/2005 Female 119 lb 6/2/2006 Netherlands
Primary
Concomitant
Soft Tissue Necrosis Hospitalization 1/1/2005 Male 132 lb 6/9/2006 Physician United States
Primary
Concomitant
Duodenitis Other Serious 5/3/2006 35 Female 6/21/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 4/12/2006 46 Female 6/23/2006 Other Health Professional Mexico
Primary
Secondary
Concomitant
Completed Suicide Death 3/27/2006 Male 165 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/9/2006 Male 176 lb 6/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 5/3/2006 35 Female 6/30/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/30/2006 Male 7/10/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 3/19/2006 42 Male 7/13/2006 Other Health Professional Sweden
Primary
Concomitant
Lacrimation Increased Other Serious 7/5/2006 Female 120 lb 7/17/2006 Consumer Canada
Primary
Concomitant
Wound Secretion Hospitalization 3/27/2006 70 Male 146 lb 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Convulsion Hospitalization 6/14/2006 Male 150 lb 7/19/2006 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/26/2006 Female 7/20/2006 Physician Belgium
Primary
Concomitant
Vertigo Hospitalization 3/9/2006 57 Female 7/31/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Rash 1/1/2006 Female 7/31/2006 Consumer United States
Primary
Concomitant
Urticaria 3/29/2004 Female 7/31/2006 Other Health Professional United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/14/2005 Male 168 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gastritis Hospitalization 6/1/2006 Female 174 lb 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 8/16/2006 Physician Brazil
Primary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 8/21/2006 Physician Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/1/2004 48 Female 8/24/2006 Physician Spain
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 1/20/2005 Female 8/31/2006 Physician Argentina
Primary
Secondary
Concomitant
Fracture Other Serious 7/25/2006 Female 114 lb 9/11/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 7/22/2006 Female 130 lb 9/13/2006 Consumer Canada
Primary
Concomitant
Tachycardia Hospitalization 8/9/2006 75 Female 9/15/2006 Physician Portugal
Primary
Concomitant
Tachycardia Hospitalization 8/9/2006 75 Female 9/21/2006 Physician Portugal
Primary
Concomitant
Facial Palsy Other Serious 7/5/2006 Female 120 lb 9/22/2006 Physician Canada
Primary
Concomitant
Pulmonary Hypertension Death 9/12/2006 18 Female 9/15/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Male 9/26/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Male 10/11/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/7/2006 Female 10/13/2006 Consumer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Required Intervention 9/1/2006 18 Female 10/4/2006 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 4/12/2005 68 Female 134 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 1/20/2005 Female 10/19/2006 Physician Argentina
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Acute Other Serious 10/23/2006 46 Female 11/1/2006 Other Health Professional Thailand
Primary
Concomitant
Appendicitis Hospitalization 10/17/2006 50 Female 140 lb 10/31/2006 Physician Mexico
Primary
Concomitant
Vision Blurred Other Serious 1/1/2006 60 Female 11/7/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/1/2006 61 Female 11/8/2006 Physician Sweden
Primary
Concomitant
Hodgkin's Disease Other Serious 9 Female 11/3/2006 Physician Japan
Primary
Concomitant
Respiratory Rate Increased Other Serious 10/23/2006 46 Female 11/13/2006 Other Health Professional Thailand
Primary
Concomitant
Uveitis Other Serious 1/1/2005 Female 11/14/2006 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Hospitalization 10/8/2006 Male 236 lb 11/17/2006 Consumer United States
Primary
Concomitant
Impaired Healing Hospitalization 10/17/2006 50 Female 140 lb 11/10/2006 Physician Mexico
Primary
Concomitant
Compression Fracture Other Serious 7/25/2006 Female 114 lb 11/18/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 9/13/2006 35 Female 205 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 5/15/2006 55 Male 216 lb 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Death 2/1/2000 63 Male 11/21/2006 United States
Primary
Concomitant
Urticaria Other Serious 7/31/2006 60 Male 178 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 9 Female 12/8/2006 Other Health Professional Japan
Primary
Concomitant
Skin Cancer 8/28/2006 Female 12/13/2006 Physician United States
Primary
Concomitant
Arthropathy Other Serious 2/4/2005 Female 101 lb 12/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Death 9/21/2006 41 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 11/2/2005 Female 119 lb 12/15/2006 Netherlands
Primary
Concomitant
Spinal Fracture Hospitalization 1/13/2005 Female 159 lb 12/15/2006 Consumer United Kingdom
Primary
Concomitant
Arthropathy Other Serious 2/4/2005 Female 101 lb 12/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash 11/1/2006 41 Female 236 lb 12/22/2006 Physician United States
Primary
Concomitant
Muscle Spasms Other Serious 7/17/2005 Female 150 lb 12/27/2006 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 5/1/2006 Male 12/27/2006 Physician Netherlands
Primary
Concomitant
Viral Myocarditis Death 9/21/2006 41 Female 12/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 12/2/2006 Female 145 lb 12/29/2006 Consumer Canada
Primary
Concomitant
Cerebral Haemorrhage Other Serious 11/26/2006 Female 183 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Femur Fracture Other Serious 8/17/2004 Female 159 lb 1/9/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 7 Female 1/15/2007
Primary
Secondary
Pulmonary Tuberculosis Other Serious 1/2/2007 68 Male 1/16/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Ovarian Cyst Ruptured Other Serious 5/17/2006 14 Female 117 lb 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 7/24/2006 Male 225 lb 1/18/2007 Portugal
Primary
Concomitant
Malaise Other Serious 10/1/2005 27 Female 1/19/2007 Physician Spain
Primary
Concomitant
Arthropathy Other Serious Female 150 lb 1/24/2007 Consumer Canada
Primary
Concomitant
Pyrexia Hospitalization 3/19/2006 42 Male 1/25/2007 Other Health Professional Sweden
Primary
Concomitant
Subcutaneous Emphysema Hospitalization 10/1/2003 66 Male 1/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer Other Serious 7/5/2006 Female 119 lb 1/27/2007 Consumer Brazil
Primary
Concomitant
Coeliac Disease Other Serious 1/18/2007 Female 94 lb 2/1/2007 Consumer Canada
Primary
Concomitant
Prostate Cancer Other Serious 7/24/2006 Male 225 lb 2/1/2007 Portugal
Primary
Concomitant
Rash Pruritic Disability 11/7/2006 Female 134 lb 2/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Epstein-barr Virus Infection Other Serious 11/1/2004 Female 2/5/2007 Netherlands
Primary
Concomitant
Haemorrhoidal Haemorrhage Other Serious 9/26/2003 Male 123 lb 2/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Histoplasmosis Disseminated Other Serious 8/11/2006 Female 124 lb 2/8/2007 Physician United States
Primary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 66 Male 2/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 11/1/2006 Female 154 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 6/8/2006 Male 123 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Head Injury Other Serious 7/30/2004 Male 123 lb 2/12/2007 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 12/3/2005 Female 119 lb 2/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Diverticulum Other Serious 9/16/2006 Male 130 lb 2/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Coeliac Disease Other Serious 1/18/2007 Female 94 lb 2/15/2007 Physician Canada
Primary
Concomitant
Skin Ulcer Hospitalization 10/10/2006 Male 168 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 5/1/2006 Male 2/21/2007 Physician Netherlands
Primary
Concomitant
Osteoporosis Hospitalization 7/4/2005 Female 159 lb 2/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gynaecomastia Other Serious 1/29/2007 Male 212 lb 2/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 5/1/2006 Male 3/2/2007 Physician Netherlands
Primary
Concomitant
Joint Abscess Hospitalization 2/1/2007 Male 132 lb 3/9/2007 Physician Colombia
Primary
Concomitant
White Blood Cell Count Increased Death 9/21/2006 41 Female 123 lb 3/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/25/2007 Female 149 lb 3/21/2007 Other Health Professional Canada
Primary
Concomitant
Respiratory Failure Other Serious 2/25/2007 Female 149 lb 3/29/2007 Other Health Professional Canada
Primary
Concomitant
Pelvic Fracture Other Serious 9/1/2006 Female 150 lb 4/2/2007 Other Health Professional Canada
Primary
Concomitant
Epstein-barr Virus Infection 11/1/2004 Female 4/5/2007 Netherlands
Primary
Concomitant
Transaminases Increased Hospitalization 9/1/2006 Female 187 lb 4/5/2007 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 12/17/2006 42 Female 128 lb 4/25/2007 Physician Spain
Primary
Secondary
Temporal Lobe Epilepsy Other Serious 4/22/2007 14 Male 5/2/2007 Other Health Professional Brazil
Primary
Concomitant
Subcutaneous Nodule Other Serious 2/1/2007 Female 5/7/2007 Consumer United States
Primary
Secondary
Concomitant

Drug Data