Doxorubicin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tongue Disorder Other Serious 12/5/2005 Male 216 lb 12/27/2005 United States
Primary
Secondary
Respiratory Distress Hospitalization 12/12/2005 72 Male 1/12/2006 France
Primary
Secondary
Concomitant
Paraesthesia Required Intervention 3/18/2006 Female 90 lb 3/27/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 6 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 10 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/4/2006 40 Female 209 lb 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 58 Female 9/1/2006 United States
Primary
Secondary
Leukoencephalopathy Other Serious 56 Male 9/21/2006 Physician United States
Primary
Secondary
Leukoencephalopathy Other Serious 56 Male 10/3/2006 Other Health Professional United States
Primary
Secondary
Lung Infection Pseudomonal Other Serious 50 Female 9/29/2006 Canada
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/1/1998 43 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 39 Male 10/17/2006 Physician United States
Primary
Concomitant
Necrotising Colitis Hospitalization 7 Female 10/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 12/7/2006 Physician Australia
Primary
Secondary
Pain In Extremity Other Serious 11/1/1998 43 Male 12/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 11/1/1998 43 Male 12/8/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 12/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/16/2005 17 Male 4/18/2007 Other Health Professional Malaysia
Primary
Secondary
Restrictive Pulmonary Disease Hospitalization 2/11/2007 65 Male 157 lb 5/14/2007 Physician France
Primary
Secondary
Concomitant
Metastasis Hospitalization 1/1/2002 67 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraparesis Life Threatening 1/1/2002 67 Female 7/20/2007 United Kingdom
Primary
Secondary
Metastasis Hospitalization 1/1/2002 40 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Movement Disorder Other Serious 6/19/2006 12 Female 97 lb 8/2/2007 Physician Germany
Primary
Concomitant
Pleocytosis Life Threatening 1/1/2002 40 Female 8/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Other Serious 14 Female 8/9/2007 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 9 Male 8/11/2007 Physician United States
Primary
Secondary
Spinal Anaesthesia Life Threatening 1/1/2002 40 Male 8/10/2007 United Kingdom
Primary
Secondary
Thymus Enlargement Other Serious 4 Male 8/15/2007 Physician Korea, Democratic People's Republic Of
Primary
Secondary
Tachycardia Other Serious 7/20/2007 35 Male 143 lb 9/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 1/1/2002 71 Male 9/4/2007
Primary
Concomitant
Metastasis Hospitalization 1/1/2002 40 Female 9/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Polyneuropathy Death 1/5/2007 Female 130 lb 9/10/2007 Consumer France
Primary
Secondary
Mass Hospitalization 2/4/2008 Physician Hong Kong
Primary
Secondary
Loss Of Consciousness Other Serious 6 Male 2/7/2008 Turkey
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Hospitalization Male 150 lb 2/8/2008 Consumer United Kingdom
Primary
Concomitant
Somnolence Death 12/19/2007 Male 176 lb 2/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Disorder Hospitalization 6/16/2008 7/28/2008 Physician Italy
Primary
Secondary
Tinnitus Hospitalization 46 Male 9/19/2008 Italy
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Splenic Rupture Other Serious 20 Male 1/29/2009 Other Health Professional Pakistan
Primary
Secondary
Death Death 4/14/2009 Physician United Kingdom
Primary
Secondary
Sudden Death Hospitalization 3/21/2009 Male 4/16/2009 Consumer United Kingdom
Primary
Secondary
Lung Disorder Hospitalization 1/10/2009 Female 4/16/2009 Consumer United Kingdom
Primary
Secondary
Vasodilatation Other Serious 1/25/2008 66 Male 4/17/2009 Physician Japan
Primary
Concomitant
Hepatic Necrosis Death 8/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 9/15/2009 Male 120 lb 11/11/2009 Physician Netherlands
Primary
Concomitant
Insulin-like Growth Factor Decreased Other Serious 12 Female 11/17/2009 Other Health Professional United States
Primary
Secondary
Epiphysiolysis Other Serious 15 Male 11/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 12/1/2009 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 59 Male 12/10/2009
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 59 Male 12/14/2009
Primary
Secondary
Concomitant
Osteoporotic Fracture Hospitalization 14 Female 2/12/2010 Italy
Primary
Secondary
Malignant Neoplasm Progression Other Serious 34 Female 2/15/2010 Other Health Professional Italy
Primary
Secondary
Post Lumbar Puncture Syndrome Hospitalization 10/13/2009 Female 209 lb 2/17/2010 Physician United Kingdom
Primary
Secondary
Epilepsy Hospitalization 2/13/2009 Female 2/19/2010 Consumer United Kingdom
Primary
Secondary
Zygomycosis Other Serious 1/1/2006 Male 2/12/2010 Physician Italy
Primary
Concomitant
Anal Abscess Hospitalization 12/8/2008 Male 157 lb 2/24/2010 Physician United Kingdom
Primary
Secondary
Loss Of Consciousness Death 1/10/2010 56 Male 3/1/2010 Spain
Primary
Concomitant
Vomiting Other Serious 2/10/2010 Male 130 lb 3/9/2010 Physician France
Primary
Concomitant
Renal Impairment Other Serious 17 Male 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 10/1/2003 34 Female 3/12/2010 Other Health Professional Japan
Primary
Secondary
Renal Impairment Other Serious 17 Male 3/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/17/2010 Physician Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/1/2005 Female 3/18/2010 Physician United States
Primary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/19/2010 Physician Italy
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 3/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Blood Thyroid Stimulating Hormone Increased Female 98 lb 6/28/2010 Pharmacist United States
Primary
Concomitant
Vena Cava Filter Insertion Other Serious 4/26/2009 23 Male 225 lb 6/30/2010 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 50 Male 7/1/2010 Other Health Professional France
Primary
Secondary
Renal Tubular Necrosis Hospitalization 1/27/2010 47 Male 9/14/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 1/27/2010 47 Male 10/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2005 65 Male 9/29/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Death 9/13/2010 76 Female 148 lb 10/28/2010 Physician United States
Primary
Secondary
Concomitant
Pneumatosis Other Serious 56 Male 11/8/2010 Physician Taiwan, Province Of China
Primary
Secondary
Vomiting Other Serious 56 Male 11/8/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Pneumatosis Hospitalization 56 Male 11/8/2010 Physician Taiwan, Province Of China
Primary
Secondary
Hepatitis B Other Serious 56 Male 12/1/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 8 Male 12/10/2010
Primary
Secondary
Subclavian Vein Thrombosis Life Threatening 7 Female 12/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Life Threatening 7 Female 12/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Peripheral T-cell Lymphoma Unspecified Stage Iv Life Threatening 1/1/2010 68 Female 12/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious Male 12/30/2010 Physician Japan
Primary
Secondary
Polyomavirus-associated Nephropathy Other Serious 55 Male 1/5/2011 Other Health Professional Japan
Primary
Secondary
Renal Failure Acute Other Serious Male 1/6/2011 Physician Japan
Primary
Secondary
Bk Virus Infection Death 55 Male 12/27/2010 Japan
Primary
Concomitant
Nerve Injury Hospitalization 50 Male 243 lb 12/23/2010 Pharmacist United States
Primary
Concomitant
Premature Baby Hospitalization 12/25/2003 Female 4 lb 1/18/2011 Physician France
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 14 Male 1/21/2011 Physician Israel
Primary
Secondary
Nephropathy Toxic Other Serious 18 Male 1/27/2011
Primary
Secondary
Renal Failure Acute Other Serious 1/1/2010 55 Male 1/28/2011 Other Health Professional Japan
Primary
Secondary
Neutropenia Other Serious 1/26/2011 72 Male 280 lb 2/2/2011 Physician United States
Primary
Concomitant
Drug Clearance Decreased Other Serious 12 Male 2/2/2011 Physician Germany
Primary
Secondary
Renal Failure Other Serious 12 Male 2/2/2011 Physician Germany
Primary
Secondary
Drug Clearance Decreased Other Serious 12 Male 2/2/2011 Physician Germany
Primary
Secondary
Infection Other Serious 2/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12 Male 2/9/2011 Other Health Professional Germany
Primary
Secondary
Breast Cancer Other Serious 1/1/2004 26 Female 2/15/2011 Other Health Professional Turkey
Primary
Secondary
Breast Cancer Other Serious 1/1/2004 26 Female 2/15/2011 Other Health Professional Turkey
Primary
Secondary
Coagulopathy Other Serious 1/1/2010 12 Male 2/15/2011 Other Health Professional Germany
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Breast Cancer Other Serious 26 Female 2/18/2011 Physician Turkey
Primary
Secondary
Eyelid Ptosis Hospitalization 69 Male 2/18/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/21/2011 Consumer United Kingdom
Primary
Secondary
Fatigue Hospitalization 78 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 54 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 55 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 70 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 65 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 37 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Breast Cancer Other Serious 26 Female 3/1/2011 Physician Turkey
Primary
Secondary
Cytomegalovirus Infection Hospitalization 4/30/2009 55 Male 3/1/2011 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 3/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 9/20/2010 32 Female 188 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Skin Infection Other Serious 10/3/2003 46 Female 128 lb 3/9/2011 Other Health Professional United States
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 17 Male 3/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Anxiety Death 3/8/2011 15 Female 144 lb 3/23/2011 Physician United States
Primary
Secondary
Platelet Count Decreased Death 3/3/2011 14 Female 90 lb 3/16/2011 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Tumour Lysis Syndrome Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Tumour Lysis Syndrome Death 3/30/2011 Physician Italy
Primary
Secondary
Convulsion Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Peripheral Nerve Palsy Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Cytomegalovirus Infection Death 3/30/2011 Physician Italy
Primary
Secondary
Convulsion Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Tumour Lysis Syndrome Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Tumour Lysis Syndrome Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Tumour Lysis Syndrome Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Sepsis Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Sepsis Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Sepsis Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Sepsis Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Sepsis Other Serious 3/30/2011 Physician Italy
Primary
Secondary
Tumour Lysis Syndrome Other Serious 3/31/2011 Physician Italy
Primary
Secondary
Hypercalcaemia Hospitalization 10/3/2003 46 Female 128 lb 4/5/2011 United States
Primary
Concomitant
Neurotoxicity Other Serious 56 Male 4/7/2011 Other Health Professional Australia
Primary
Secondary
Areflexia Other Serious 81 Male 4/7/2011 Other Health Professional Australia
Primary
Secondary
Areflexia Other Serious 30 Female 4/7/2011 Other Health Professional Australia
Primary
Secondary
Neurotoxicity Other Serious 30 Male 4/7/2011 Other Health Professional Australia
Primary
Secondary
Neurotoxicity Other Serious 31 Male 4/7/2011 Other Health Professional Australia
Primary
Secondary
Neurotoxicity Other Serious 68 Male 4/7/2011 Other Health Professional Australia
Primary
Secondary
Neurotoxicity Other Serious 57 Female 4/7/2011 Other Health Professional Australia
Primary
Secondary
Neurotoxicity Other Serious 49 Female 4/7/2011 Other Health Professional Australia
Primary
Secondary
Leukopenia Life Threatening 3/16/2011 50 Male 4/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Agranulocytosis Hospitalization 2/4/2011 64 Male 4/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Death 4/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Agranulocytosis Life Threatening 3/16/2011 50 Male 4/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haemangioma Other Serious Male 4/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Premature Labour Other Serious 4/13/2011 Other Health Professional United Kingdom
Primary
Secondary

Drug Data