Fentanyl combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overdose Required Intervention 10/19/2005 77 Female 127 lb 1/2/2006 Consumer United States
Primary
Concomitant
Penis Carcinoma Other Serious 11/3/2005 Male 229 lb 1/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 11/10/2005 79 Female 1/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/20/2005 Male 152 lb 1/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 11/10/2005 79 Female 1/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Hospitalization 1/8/2005 34 Female 1/20/2006 Other Health Professional Norway
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 1/8/2006 Female 135 lb 1/26/2006 Canada
Primary
Concomitant
Hepatic Failure Hospitalization 10/26/2005 44 Female 1/24/2006 Physician Germany
Primary
Concomitant
Vomiting Other Serious 2/6/2006 85 Male 137 lb 2/6/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/30/2006 Male 119 lb 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 5/2/2006 Male 240 lb 7/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Hospitalization 6/1/2006 Female 126 lb 10/11/2006 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/9/2006 Female 190 lb 11/2/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Life Threatening 7/1/2006 Female 143 lb 11/17/2006 Physician Germany
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Pyrexia Hospitalization 8/25/2006 Female 213 lb 12/13/2006 Physician United States
Primary
Concomitant
Angioneurotic Oedema Required Intervention 63 Female 3/6/2006 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 7/6/2006 42 Female 1/26/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Vaginal Haemorrhage Life Threatening 3/21/2007 32 Female 134 lb 3/27/2007 United States
Primary
Secondary
Concomitant
Neoplasm Other Serious 3/30/2007 56 Female 138 lb 4/5/2007 Consumer Canada
Primary
Concomitant
Neoplasm Other Serious 3/30/2007 56 Female 138 lb 4/20/2007 Consumer Canada
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/4/2006 79 Female 150 lb 5/23/2007 Other Health Professional United States
Primary
Concomitant
Sarcoma Other Serious 5/21/2007 56 Female 6/22/2007 Physician Canada
Primary
Concomitant
Swelling Face Other Serious 6/2/2007 Male 174 lb 7/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 7/19/2007 Male 148 lb 8/3/2007 Canada
Primary
Concomitant
Hospitalisation Hospitalization 7/23/2007 62 Female 9/4/2007 Consumer Canada
Primary
Concomitant
Osteitis Deformans 5/21/2007 56 Female 9/4/2007 Physician Canada
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 7/19/2007 Male 148 lb 9/5/2007 Canada
Primary
Concomitant
Swelling Face Other Serious 6/2/2007 Male 174 lb 9/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 1/1/2007 62 Female 9/11/2007 Consumer Canada
Primary
Concomitant
Swelling Face Other Serious 6/2/2007 Male 174 lb 10/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Other Serious 10/18/2007 Male 148 lb 11/9/2007 Canada
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 9/5/2007 Female 244 lb 11/14/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious Female 174 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gastric Polyps 5/24/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 6/1/1998 53 Female 143 lb 12/20/2007 Physician United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 6/1/2006 Female 1/17/2008 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 6/1/1998 53 Female 143 lb 2/4/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 Female 99 lb 2/7/2008 Consumer United States
Primary
Concomitant
Hyperlipidaemia Other Serious 5 Male 44 lb 2/27/2008
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 10/14/2005 Female 137 lb 3/13/2008 Physician Italy
Primary
Concomitant
Maximal Voluntary Ventilation Decreased Hospitalization 3/1/2006 Female 137 lb 3/14/2008 Physician Italy
Primary
Concomitant
Nephropathy Toxic Other Serious 13 Male 3/21/2008 Pharmacist United States
Primary
Concomitant
Rash Other Serious 1/1/2006 Female 175 lb 3/31/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2007 Female 99 lb 4/11/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2007 Female 71 lb 5/21/2008 Consumer United States
Primary
Concomitant
Rash Pustular 3/1/2008 Female 6/13/2008 United States
Primary
Concomitant
Respiratory Disorder Other Serious 10/1/2007 Female 140 lb 6/13/2008 United States
Primary
Secondary
Concomitant
Shoulder Operation Other Serious 6/19/2008 Female 138 lb 6/27/2008 Consumer United States
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 6/8/2008 Male 141 lb 7/1/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 81 Female 7/3/2008 Consumer Canada
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 6/19/2008 Female 138 lb 7/11/2008 Consumer United States
Primary
Concomitant
Death Hospitalization 6/8/2008 Male 141 lb 7/18/2008 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Death 3/21/2008 71 Male 9/8/2008 Physician Japan
Primary
Concomitant
Psoriasis 12/1/2006 Female 190 lb 9/12/2008 Consumer United States
Primary
Concomitant
Respiratory Disorder Other Serious 9/26/2007 Female 130 lb 9/12/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Female 105 lb 9/12/2008 Consumer United States
Primary
Concomitant
Musculoskeletal Pain 7/1/2008 Female 123 lb 9/13/2008 Physician
Primary
Concomitant
Swelling Face Other Serious Male 9/24/2008 Consumer United Kingdom
Primary
Concomitant
Shock Other Serious 11/30/2007 Male 35 lb 11/3/2008 Other Health Professional Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Latent Tuberculosis Death Female 11/17/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 5/1/2007 Female 198 lb 11/19/2008 Germany
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 11/1/2007 Male 225 lb 11/19/2008 United Kingdom
Primary
Concomitant
Medical Device Complication Other Serious 7/1/2008 Female 172 lb 11/21/2008 Consumer United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 1/1/2007 Female 180 lb 3/10/2009 Consumer United States
Primary
Concomitant
Splenic Abscess Other Serious 11/16/2008 39 Female 126 lb 4/15/2009 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia 11/10/2008 Female 6/11/2009 United States
Primary
Concomitant
Headache 12/1/2008 Female 120 lb 6/11/2009 Consumer United States
Primary
Concomitant
Pain 1/1/2009 Female 115 lb 6/12/2009 Physician United States
Primary
Concomitant
Ill-defined Disorder 5/1/2009 Female 170 lb 6/12/2009 Consumer United States
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 3/26/2008 Male 6/11/2009 Physician United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 5/7/2009 Female 6/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/1/2008 79 Female 6/30/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 5/7/2009 Female 7/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Optic Neuropathy Other Serious 4/22/2009 Female 241 lb 7/14/2009 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 6/1/2009 Female 134 lb 9/3/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 67 Male 157 lb 9/1/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/4/2009 Male 9/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/1/2008 79 Female 9/15/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 6/16/2009 Male 265 lb 9/19/2009 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 160 lb 9/15/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/4/2009 Male 9/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 57 Female 175 lb 10/22/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/15/2009 Female 123 lb 1/18/2010 United Kingdom
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Pain In Extremity 10/1/2008 Male 1/29/2010 Other Health Professional United States
Primary
Concomitant
Sinusitis 1/1/2008 Female 180 lb 1/29/2010 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2007 Female 2/5/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 11/1/2009 Female 3/8/2010 Physician Canada
Primary
Concomitant
Pain In Extremity Other Serious 6/9/2009 Female 205 lb 3/12/2010 Other Health Professional Canada
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 Female 3/12/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 Female 3/25/2010 Other Health Professional United States
Primary
Concomitant
Radiation Injury Other Serious 8/9/2007 Female 196 lb 3/25/2010 Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/24/2009 Female 181 lb 3/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/1/2010 66 Female 4/30/2010 Consumer United States
Primary
Concomitant
Palpitations 3/6/2009 76 Female 144 lb 5/3/2010 Consumer United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 5/1/2000 48 Female 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 48 Female 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 5/28/2010 United States
Primary
Concomitant
Hepatotoxicity Other Serious 3 Male 24 lb 5/31/2010 Physician Turkey
Primary
Concomitant
Hernia Other Serious 5/1/2010 41 Male 190 lb 6/11/2010 Consumer United States
Primary
Concomitant
Vaginal Lesion Hospitalization 4/14/2010 3 Female 43 lb 6/17/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/4/2010 3 Female 43 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Vomiting 6/22/2010 66 Female 130 lb 7/6/2010 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 7/7/2009 46 Female 143 lb 6/28/2010 Physician Lithuania
Primary
Concomitant
Swelling Face Other Serious 1/1/2010 46 Male 7/7/2010 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/1999 48 Female 7/16/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting 11/1/2007 44 Female 115 lb 7/17/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 2/1/2010 66 Female 7/16/2010 Consumer United States
Primary
Concomitant
Surgery Other Serious Female 7/15/2010 Consumer United States
Primary
Concomitant
Incontinence Other Serious 8/9/2007 51 Female 196 lb 8/5/2010 Physician Germany
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious Female 8/16/2010 Physician United States
Primary
Concomitant
Withdrawal Syndrome Required Intervention 6/2/2010 49 Female 120 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2009 49 Female 9/16/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 6/1/2010 13 Male 120 lb 10/22/2010 Physician Netherlands
Primary
Concomitant
Varicella Virus Test Positive Other Serious 10/1/2007 21 Female 154 lb 11/12/2010 Other Health Professional Japan
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 11/30/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/1/2010 31 Female 170 lb 11/30/2010 Consumer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 8/29/2007 59 Female 12/2/2010 Physician United States
Primary
Secondary
Concomitant
Mouth Haemorrhage Death 4/25/2009 4 Female 32 lb 12/8/2010 Physician Japan
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 9/1/2007 12/14/2010 Other Health Professional United States
Primary
Concomitant
Tremor 12/14/2010 Consumer United States
Primary
Concomitant
Migraine 12/15/2010 Consumer United States
Primary
Concomitant
Abdominal Pain 6/1/2010 59 Female 182 lb 11/6/2010 Consumer United States
Primary
Concomitant
Myoclonus Hospitalization 10/8/2010 41 Female 12/23/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 9/8/2010 49 Female 161 lb 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Joint Stiffness Death 12/17/2010 58 Female 1/7/2011 Consumer United States
Primary
Secondary
Concomitant
Hydronephrosis Other Serious 5/30/1996 48 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Reconstruction Hospitalization 8/9/2007 51 Female 174 lb 1/17/2011 Physician Germany
Primary
Secondary
Concomitant
Blister Hospitalization 12/18/2010 75 Female 255 lb 1/5/2011 Other Health Professional United States
Primary
Concomitant
Infection Death 4/25/2009 4 Female 32 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Grip Strength Decreased 1/1/2010 56 Female 1/29/2011 Consumer United States
Primary
Concomitant
Scratch 11/1/2010 54 Female 1/30/2011 Consumer United States
Primary
Concomitant
Diverticulum 7/18/2009 54 Female 1/30/2011 Other Health Professional United States
Primary
Concomitant
Fall Hospitalization 7/24/2010 69 Female 110 lb 1/30/2011 Physician United States
Primary
Concomitant
Injection Site Haematoma 9/14/2010 54 Female 1/30/2011 Consumer United States
Primary
Concomitant
Hepatitis Other Serious 1/1/2009 38 Female 83 lb 2/3/2011 Consumer United States
Primary
Concomitant
Bursitis Death 6/1/2010 58 Female 2/7/2011 Physician United States
Primary
Concomitant
Dysphagia Hospitalization 12/25/2010 82 Female 95 lb 2/7/2011 Other Health Professional Canada
Primary
Concomitant
Influenza Like Illness Life Threatening 3/6/2009 76 Female 144 lb 2/8/2011 Consumer United States
Primary
Secondary
Concomitant
Local Swelling Hospitalization 12/25/2010 82 Female 95 lb 2/8/2011 Other Health Professional Canada
Primary
Concomitant
Renal Atrophy Other Serious 5/30/1996 48 Female 2/10/2011 United States
Primary
Secondary
Concomitant
Anxiety Other Serious 5/30/1996 48 Female 2/14/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data