Methotrexate combined with Sulphasalazine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Other Serious 6/25/2008 Female 1/6/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 11/15/2007 Female 117 lb 1/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cholecystectomy Hospitalization 10/15/2009 Female 1/26/2010 United Kingdom
Primary
Concomitant
Subdural Haematoma Death 4/25/2009 87 Female 123 lb 1/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 4/7/2009 Female 2/3/2010 United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 5/15/2009 76 Female 2/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ovarian Cyst Hospitalization 7/15/2009 Female 2/12/2010 United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/26/2009 Male 185 lb 2/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 2/23/2010 Australia
Primary
Concomitant
Death Death Female 2/24/2010 Physician United Kingdom
Primary
Concomitant
Breast Cancer In Situ Other Serious 4/1/2009 65 Female 174 lb 3/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 2/23/2010 Female 214 lb 3/15/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/17/2010 45 Female 110 lb 3/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 3/25/2009 Female 3/22/2010 United Kingdom
Primary
Concomitant
Recurrent Cancer Other Serious 6/17/2009 Male 220 lb 3/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cholecystitis Acute Other Serious 10/15/2009 66 Female 4/2/2010 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 4/14/2009 51 Female 4/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 10/19/2009 62 Female 178 lb 4/5/2010 Physician Singapore
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 2/5/2010 46 Female 225 lb 4/6/2010 Physician Brazil
Primary
Secondary
Concomitant
Death Death Female 4/6/2010 Physician United Kingdom
Primary
Concomitant
Wound Necrosis Other Serious 7/15/2009 61 Female 4/7/2010 United Kingdom
Primary
Concomitant
Cholecystitis Acute Other Serious 10/15/2009 66 Female 4/15/2010 United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 2/5/2010 46 Female 225 lb 4/22/2010 Physician Brazil
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 10/19/2009 62 Female 178 lb 4/30/2010 Physician Singapore
Primary
Secondary
Concomitant
Metastatic Renal Cell Carcinoma Other Serious 5/15/2009 62 Male 5/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Chorioretinopathy Disability 10/18/2009 43 Female 5/20/2010 Physician United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Death Male 5/24/2010 United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Hospitalization Male 6/3/2010 Physician United Kingdom
Primary
Concomitant
Uveitis Other Serious 11/1/2008 59 Female 139 lb 6/17/2010 Physician United Kingdom
Primary
Concomitant
Fracture Hospitalization 1/21/2010 43 Female 6/18/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 6/23/2010 51 Female 269 lb 6/29/2010 Physician Egypt
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 63 Male 7/16/2010 Physician Australia
Primary
Concomitant
Skin Ulcer Hospitalization 2/5/2010 46 Female 225 lb 7/27/2010 Physician Brazil
Primary
Secondary
Concomitant
Rectocele Other Serious 10/15/2009 61 Female 165 lb 7/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Death 11/19/2009 69 Male 179 lb 8/6/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 63 Male 8/18/2010 Physician Australia
Primary
Concomitant
Nerve Compression Other Serious 7/8/2009 66 Female 203 lb 8/20/2010 Consumer United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/18/2010 55 Female 176 lb 8/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Death 8/25/2009 68 Male 8/31/2010 Consumer United Kingdom
Primary
Concomitant
Cerebrovascular Accident Death 9/9/2009 70 Male 183 lb 9/20/2010 Consumer United Kingdom
Primary
Concomitant
Cerebrovascular Accident Death 9/9/2009 70 Male 183 lb 9/22/2010 Consumer United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious Female 10/4/2010 Physician Ireland
Primary
Concomitant
Drug Ineffective Other Serious Female 10/5/2010 Physician Ireland
Primary
Concomitant
Rash Hospitalization 1/1/2008 65 Female 10/27/2010 Physician Japan
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 3/15/2009 10/29/2010 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization Female 11/3/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 6/5/2010 68 Female 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ischaemic Stroke Hospitalization 2/18/2010 55 Female 176 lb 11/11/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 11/4/2009 84 Female 123 lb 11/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Skin Cancer Other Serious 9/28/2008 68 Female 168 lb 11/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 5/22/2009 80 Male 119 lb 11/22/2010 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/29/2007 48 Female 150 lb 11/22/2010 Consumer United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 3/19/2010 53 Female 128 lb 11/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 8/11/2010 59 Female 150 lb 11/23/2010 Consumer United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 11/4/2009 84 Female 123 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Gallbladder Operation Other Serious 9/1/2010 44 Female 139 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Gallbladder Operation Other Serious 9/1/2010 44 Female 139 lb 12/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 3/19/2010 53 Female 128 lb 12/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hydronephrosis Hospitalization 10/16/2009 62 Female 117 lb 12/10/2010 Consumer United Kingdom
Primary
Concomitant
Cellulitis Hospitalization 7/23/2010 74 Male 12/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cancer Metastatic Other Serious 2/15/2008 68 Male 192 lb 11/25/2010 United Kingdom
Primary
Concomitant
Sarcoma Metastatic Death 10/17/2010 86 Female 139 lb 12/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Death 6/19/2009 69 Male 183 lb 12/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Skin Lesion Other Serious 12/3/2008 72 Female 12/20/2010 Physician United Kingdom
Primary
Concomitant
Bursitis Hospitalization 7/23/2010 74 Male 1/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 1/11/2011 75 Male 214 lb 2/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 10/22/2010 55 Female 2/10/2011 Physician Japan
Primary
Concomitant
Circulatory Collapse Hospitalization 1/1/2009 66 Female 119 lb 2/14/2011 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 10/22/2010 55 Female 2/14/2011 Physician Japan
Primary
Concomitant
Urinary Tract Infection Death 10/26/2010 75 Male 141 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Disorder Death 10/26/2010 75 Male 141 lb 2/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Colon Cancer Death Male 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypercoagulation Death 6/19/2009 69 Male 183 lb 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 10/22/2010 55 Female 2/21/2011 Physician Japan
Primary
Concomitant
Developmental Delay Other Serious 9/10/2006 4 Male 3/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Organising Pneumonia Other Serious 9/1/2010 63 Female 165 lb 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Cancer Hospitalization 11/1/2010 64 Male 3/7/2011 Physician United Kingdom
Primary
Concomitant
Bladder Neoplasm Other Serious 11/12/2008 67 Male 3/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 6/4/2010 61 Female 218 lb 3/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acidosis Death 9/1/2010 63 Female 165 lb 3/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 11/19/2009 69 Male 179 lb 3/16/2011 Consumer United Kingdom
Primary
Concomitant
Pneumonia Other Serious 7/1/2010 63 Female 165 lb 3/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 12/1/2007 Male 3/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Squamous Cell Carcinoma Other Serious 3/12/2010 74 Female 143 lb 3/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonitis Death 4/1/2010 63 Female 154 lb 3/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Alopecia Hospitalization 1/26/2010 60 Female 4/7/2011 Physician Germany
Primary
Concomitant
Swelling Face Other Serious 10/5/2010 30 Female 3/30/2011 Physician United Kingdom
Primary
Concomitant
Viral Infection Hospitalization 2/21/2011 52 Female 141 lb 4/13/2011 Physician United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Death Female 218 lb 4/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 3/19/2011 59 Female 4/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 5/15/2010 43 Female 4/27/2011 Physician United Kingdom
Primary
Concomitant
Joint Dislocation Hospitalization 12/20/2010 66 Female 205 lb 4/28/2011 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 3/17/2011 55 Female 185 lb 5/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Colon Cancer Other Serious 5/27/2010 58 Female 163 lb 5/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 10/22/2010 55 Female 101 lb 5/13/2011 Physician Japan
Primary
Concomitant
Vomiting Death 1/10/2006 70 Female 126 lb 11/6/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 5/22/2009 81 Male 119 lb 6/5/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Joint Dislocation Hospitalization 12/20/2010 66 Female 205 lb 2/26/2013 Consumer Country Not Specified
Primary
Concomitant
Rectal Haemorrhage Other Serious 4/5/2011 48 Male 397 lb 7/17/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Suprapubic Pain Hospitalization 12/12/2010 74 Female 3/12/2013 Physician Country Not Specified
Primary
Concomitant
Spinal Decompression Hospitalization 6/2011 81 Female 9/24/2013 Other Health Professional Gb
Primary
Concomitant
Breast Cancer In Situ Hospitalization Female 10/10/2012 Physician Gb
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 12/29/2011 65 Male 11/30/2012 Consumer Gb
Primary
Concomitant
Multiple Sclerosis Other Serious 3/2012 55 Female 10/8/2012 Physician Gr
Primary
Concomitant
Bronchial Carcinoma Hospitalization 5/9/2012 58 Female 10/30/2012 Physician Gb
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/5/2012 50 Female 9/5/2012 Other Health Professional Au
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 74 Male 11/19/2012 Other Health Professional Gb
Primary
Concomitant
Vomiting Hospitalization Female 161 lb 10/1/2012 Physician Gb
Primary
Concomitant
Atrial Fibrillation Hospitalization Female 287 lb 11/6/2012 Physician Gb
Primary
Concomitant
Pituitary Tumour Other Serious 6/15/2012 63 Male 256 lb 9/24/2012 Other Health Professional Gb
Primary
Concomitant
Vein Disorder Hospitalization 6/21/2012 69 Female 165 lb 10/1/2012 Consumer Gb
Primary
Concomitant
Non-hodgkin's Lymphoma Death 63 Male 11/20/2012 Physician Gb
Primary
Concomitant
Breast Cancer Life Threatening 6/6/2011 49 Female 139 lb 5/8/2013 Other Health Professional Gb
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/25/2012 64 Male 11/30/2012 Other Health Professional Gb
Primary
Concomitant
Myocardial Infarction Hospitalization 11/2012 Female 3/28/2013 Other Health Professional Gb
Primary
Concomitant
Endometrial Adenocarcinoma Life Threatening 10/31/2012 55 Female 12/6/2012 Other Health Professional Gb
Primary
Concomitant
Vasculitic Rash Other Serious 9/17/2012 51 Female 161 lb 7/22/2013 Physician Tr
Primary
Secondary
Concomitant
Anaemia Hospitalization Female 12/24/2012 Physician Gb
Primary
Concomitant
Respiratory Distress Other Serious 2011 37 Female 99 lb 7/11/2013 Other Health Professional Pe
Primary
Concomitant
Joint Injury Other Serious Female 214 lb 1/9/2013 Physician Gb
Primary
Concomitant
Pulmonary Fibrosis Other Serious 3/15/2012 Male 163 lb 1/18/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 8/16/2012 64 Male 1/22/2013 Physician Gb
Primary
Concomitant
Maternal Exposure Before Pregnancy Other Serious 3/15/2012 38 Female 137 lb 3/7/2013 Other Health Professional Gb
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iv Life Threatening 11/2012 68 Male 174 lb 1/25/2013 Consumer Gb
Primary
Concomitant
Drug Ineffective NotSpecified 1/28/2013 Consumer Us
Primary
Concomitant
Dyspnoea Other Serious Male 2/6/2013 Other Health Professional Gb
Primary
Concomitant
Non-hodgkin's Lymphoma Death 65 Male 207 lb 2/15/2013 Physician Gb
Primary
Concomitant
Endometrial Cancer Other Serious 6/18/2010 54 Female 3/22/2013 Physician Gb
Primary
Concomitant
Myeloproliferative Disorder Other Serious 5/22/2012 55 Female 3/1/2013 Other Health Professional Gb
Primary
Concomitant
Psoriasis Hospitalization 12/30/2012 78 Female 3/5/2013 Other Health Professional Gb
Primary
Concomitant
Respiratory Failure Death 11/3/2012 76 Female 106 lb 3/6/2013 Physician Gb
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious Male 3/18/2013 Physician Country Not Specified
Primary
Concomitant
Pneumonia Hospitalization 11/1/2012 65 Female 5/21/2013 Physician Gb
Primary
Concomitant
Implant Site Reaction Hospitalization 1/3/2013 59 Male 203 lb 5/8/2013 Physician Gb
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 6/15/2012 45 Female 4/15/2013 Other Health Professional Gb
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 10/27/2011 64 Male 4/14/2013 Physician Gb
Primary
Concomitant
Malignant Melanoma Death 2/15/2011 63 Female 154 lb 4/23/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 3/5/2013 49 Female 112 lb 7/17/2013 Consumer Country Not Specified
Primary
Concomitant
Pneumonia Hospitalization 3/13/2013 58 Female 168 lb 5/3/2013 Consumer Gb
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/17/2013 55 Male 6/16/2013 Other Health Professional Nz
Primary
Concomitant
Mouth Haemorrhage Hospitalization 5/1/2013 47 Male 165 lb 7/24/2013 Physician Tr
Primary
Concomitant
Death Death 5/18/2013 77 Male 6/19/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Sepsis Other Serious 75 Female 139 lb 6/20/2013 Physician Gb
Primary
Concomitant
Pallor 5/2013 47 Male 9/4/2013 Physician Us
Primary
Concomitant
Pulmonary Fibrosis Death Female 7/24/2013 Physician Gb
Primary
Concomitant
Cholecystitis Other Serious 51 Female 7/25/2013 Other Health Professional Gb
Primary
Concomitant
Respiratory Tract Infection Viral Other Serious 68 Female 7/25/2013 Other Health Professional Gb
Primary
Concomitant
Carcinoma In Situ Of Skin Other Serious Female 181 lb 7/29/2013 Physician Gb
Primary
Concomitant
Hypersensitivity Other Serious Male 8/4/2013 Physician Gb
Primary
Concomitant
Rectal Haemorrhage Hospitalization Female 8/6/2013 Physician Gb
Primary
Concomitant

Drug Data