Methotrexate combined with Paroxetine Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Breast Cancer Life Threatening Female 176 lb 3/21/2006 Physician Netherlands
Primary
Concomitant
Optic Neuritis Retrobulbar Hospitalization 55 Male 4/7/2006 United States
Primary
Concomitant
Nausea Hospitalization 3/17/2006 Female 137 lb 4/11/2006 Other Health Professional Belgium
Primary
Concomitant
Drug Ineffective 4/1/2005 61 Female 8/10/2006 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/24/2004 60 Female 8/11/2006 Other Health Professional France
Primary
Concomitant
Synovitis Required Intervention 12/28/2005 36 Female 8/18/2006 Physician Argentina
Primary
Concomitant
Infection Hospitalization 9/6/2006 Female 10/13/2006 Consumer United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 6/13/2006 74 Male 198 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Postoperative Infection Other Serious 12/10/2004 Female 267 lb 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Lower Limb Fracture Other Serious 6/6/2005 Female 267 lb 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Sepsis Other Serious 9/24/2004 45 Female 168 lb 11/21/2006 France
Primary
Secondary
Concomitant
Lower Limb Fracture Other Serious 6/6/2005 Female 267 lb 12/13/2006 Consumer United Kingdom
Primary
Concomitant
Synovitis Required Intervention 12/28/2004 35 Female 132 lb 12/22/2006 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 11/1/2006 58 Female 150 lb 1/6/2007 France
Primary
Secondary
Concomitant
Angioneurotic Oedema Required Intervention 63 Female 3/6/2006 Physician United States
Primary
Concomitant
Myoclonus Disability 1/19/2007 58 Female 174 lb 2/7/2007 Physician France
Primary
Secondary
Concomitant
Infection Hospitalization 9/6/2006 Female 2/8/2007 Consumer United Kingdom
Primary
Concomitant
Laryngeal Cancer Disability 79 Male 121 lb 3/9/2007 Other Health Professional France
Primary
Concomitant
Myoclonus Disability 1/19/2007 58 Female 174 lb 3/16/2007 Physician France
Primary
Secondary
Concomitant
Death Death 9/1/2006 73 Female 6/15/2007 Physician France
Primary
Concomitant
Malaise Other Serious 1/1/2007 70 Female 220 lb 6/27/2007 Consumer United States
Primary
Concomitant
Nodal Marginal Zone B-cell Lymphoma Other Serious 10/15/2007 Female 152 lb 11/7/2007 United States
Primary
Concomitant
Syncope Other Serious 1/1/2004 Female 103 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Urticaria 9/11/2007 Female 200 lb 12/14/2007 United States
Primary
Concomitant
Adverse Event 1/1/2007 Male 220 lb 12/14/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/1/2007 Female 227 lb 12/14/2007 Consumer United States
Primary
Concomitant
Tendon Rupture Hospitalization 1/21/2007 Female 145 lb 12/28/2007 Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 10/1/2007 Female 196 lb 1/3/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 2/11/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/13/2006 74 Male 198 lb 3/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 11/16/2007 Female 3/14/2008 United States
Primary
Concomitant
Swelling Face 12/14/2007 Female 321 lb 3/14/2008 United States
Primary
Concomitant
Injection Site Irritation 12/17/2007 Female 175 lb 3/14/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 1/28/2008 Female 235 lb 3/15/2008 Consumer United States
Primary
Secondary
Concomitant
Skin Lesion 2/6/2008 Female 155 lb 3/15/2008 United States
Primary
Concomitant
Mental Impairment 2/16/2008 3/15/2008 United States
Primary
Concomitant
Procedural Complication 2/25/2008 Female 190 lb 3/15/2008 Consumer United States
Primary
Concomitant
Photosensitivity Reaction Other Serious 11/7/2007 66 Female 3/11/2008 Other Health Professional Denmark
Primary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 4/3/2008 Consumer United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 4/1/2006 Female 134 lb 4/10/2008 Physician Italy
Primary
Concomitant
Renal Failure Hospitalization 7/21/2007 Male 4/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/8/2007 Female 185 lb 4/14/2008 Consumer Canada
Primary
Secondary
Concomitant
Nodal Marginal Zone B-cell Lymphoma Other Serious 10/15/2007 Female 152 lb 5/2/2008 United States
Primary
Concomitant
Eyelid Ptosis Hospitalization 3/15/2008 70 Female 5/23/2008 Physician France
Primary
Secondary
Concomitant
Strabismus Hospitalization 3/15/2008 70 Female 5/28/2008 Consumer France
Primary
Secondary
Concomitant
Eyelid Ptosis Hospitalization 3/15/2008 70 Female 5/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
Mental Impairment 2/16/2008 6/12/2008 United States
Primary
Concomitant
Injection Site Pain 12/1/2007 Female 240 lb 6/12/2008 United States
Primary
Concomitant
Nausea 3/26/2008 Female 210 lb 6/12/2008 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/19/2008 Female 190 lb 6/12/2008 United States
Primary
Concomitant
Overdose 3/17/2008 Female 232 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Urticaria 4/15/2008 Female 165 lb 6/12/2008 Consumer United States
Primary
Concomitant
Paraesthesia 5/1/2008 Female 225 lb 6/13/2008 United States
Primary
Concomitant
Injection Site Bruising 5/23/2008 Female 198 lb 6/13/2008 Consumer United States
Primary
Concomitant
Eyelid Ptosis Hospitalization 3/15/2008 70 Female 6/17/2008 Physician France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/29/2008 Female 6/20/2008 Physician France
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 10/1/2000 Female 7/17/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Life Threatening 4/11/2008 Male 7/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tremor 5/1/2008 Female 210 lb 9/12/2008 Consumer United States
Primary
Concomitant
Streptococcal Infection 7/7/2008 Female 200 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Pain 6/1/2008 Female 164 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Overdose 3/17/2008 Female 232 lb 9/13/2008 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization 8/30/2008 Male 183 lb 9/19/2008 Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 10/10/2008 Canada
Primary
Secondary
Concomitant
Peritonitis Life Threatening 6/10/2008 Female 10/17/2008 Physician France
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 1/1/2008 Female 10/8/2008 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 10/24/2008 Canada
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/30/2008 Male 183 lb 11/14/2008 Canada
Primary
Secondary
Concomitant
Rash Generalised 7/18/2008 Female 200 lb 11/20/2008 United States
Primary
Concomitant
Respiratory Failure Death 10/1/2008 Male 208 lb 11/24/2008 Canada
Primary
Concomitant
Hypersensitivity Other Serious 8/2/2008 Female 11/24/2008 Belgium
Primary
Concomitant
Respiratory Failure Death 10/1/2008 Male 208 lb 12/11/2008 Canada
Primary
Concomitant
Drug Ineffective Female 200 lb 12/12/2008 Consumer United States
Primary
Concomitant
Tremor 5/1/2008 Female 210 lb 12/12/2008 Consumer United States
Primary
Concomitant
Nausea 8/30/2008 Female 12/12/2008 United States
Primary
Concomitant
Electrocardiogram Change 10/1/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Swelling 1/1/2008 Female 12/12/2008 United States
Primary
Concomitant
Vomiting 43 Female 200 lb 1/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Histoplasmosis Hospitalization 5/16/2002 46 Female 238 lb 2/13/2009 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2005 Female 155 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Silent Myocardial Infarction Hospitalization 10/1/2008 47 Female 6/17/2009 Consumer Brazil
Primary
Concomitant
Thrombocytopenia Other Serious 7/17/2009 79 Female 8/5/2009 Physician Italy
Primary
Concomitant
Respiratory Failure Life Threatening 8/29/2008 Female 159 lb 8/21/2009 Physician Argentina
Primary
Secondary
Concomitant
Wound Dehiscence Death 40 Female United States
Primary
Concomitant
Incorrect Dose Administered 5/30/2007 Male 212 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 1/28/2008 Female 235 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Haematoma 5/23/2008 Female 198 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pain 6/6/2009 Male 9/18/2009 United States
Primary
Concomitant
Drug Ineffective Female 200 lb 9/19/2009 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 9/21/2009 Canada
Primary
Secondary
Concomitant
Stress 5/1/2007 Female 156 lb 12/8/2009 Physician United States
Primary
Concomitant
Syncope Other Serious 1/1/2008 47 Female 1/25/2010 Consumer Brazil
Primary
Concomitant
Agranulocytosis Hospitalization 7/7/2009 Male 1/26/2010 Physician United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 1/18/2010 Female 232 lb 1/26/2010 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 1/18/2010 Female 232 lb 2/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Uterine Cyst Other Serious 12/1/2009 Female 209 lb 2/11/2010 Brazil
Primary
Concomitant
Rash Other Serious 11/19/2009 Female 3/18/2010 United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 41 Female 153 lb 4/6/2010 Brazil
Primary
Concomitant
Tendon Rupture Other Serious 1/1/2009 51 Female 154 lb 4/15/2010 Brazil
Primary
Concomitant
Syncope Other Serious 1/1/2008 47 Female 4/16/2010 Consumer Brazil
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/1/2009 69 Male 202 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2008 49 Female 137 lb 7/29/2010 Consumer United Kingdom
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/1/2010 27 Female 8/23/2010 Other Health Professional France
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 5/1/2010 39 Male 196 lb 10/5/2010 Physician France
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2009 47 Female 10/5/2010 Physician France
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 1/1/2009 47 Female 10/8/2010 Consumer France
Primary
Secondary
Concomitant
Rash Other Serious 3/20/2008 57 Female 10/11/2010 Physician United States
Primary
Concomitant
Vertigo Other Serious 1/1/2009 48 Female 10/13/2010 Physician France
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 3/1/2010 11/12/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 1/1/2009 51 Female 154 lb 11/17/2010 Consumer Brazil
Primary
Concomitant
Vertigo Hospitalization 5/1/2010 39 Male 196 lb 11/18/2010 Physician France
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 3/1/2010 11/23/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 5/1/2010 39 Male 196 lb 12/14/2010 Physician France
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 1/1/2008 58 Female 200 lb 1/25/2011 Consumer United States
Primary
Concomitant
Neuroma 1/1/2008 59 Female 118 lb 1/28/2011
Primary
Concomitant
Arthralgia 12/21/2009 59 Female 130 lb 1/28/2011
Primary
Concomitant
Bronchitis Hospitalization Male 240 lb 1/28/2011 Consumer United States
Primary
Concomitant
Headache 8/16/2010 59 Female 1/29/2011 Consumer United States
Primary
Concomitant
Contusion 9/1/2010 52 Female 1/29/2011 Consumer United States
Primary
Concomitant
Nasal Congestion 11/28/2010 69 Female 1/30/2011 Consumer United States
Primary
Concomitant
Urine Odour Abnormal 8/1/2010 58 Female 1/30/2011 Consumer United States
Primary
Concomitant
Gait Disturbance Hospitalization 1/1/2010 84 Female 135 lb 1/30/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1/1/2010 63 Female 176 lb 2/9/2011 Consumer United Kingdom
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious Male 183 lb 3/7/2011 Other Health Professional Canada
Primary
Concomitant
Diarrhoea Other Serious 1/20/2011 48 Female 172 lb 3/8/2011 Consumer Canada
Primary
Concomitant
Oedema Other Serious 1/20/2011 48 Female 172 lb 3/21/2011 Consumer Canada
Primary
Concomitant
Oedema Mouth Hospitalization 7/1/2010 52 Female 137 lb 3/25/2011 Consumer United States
Primary
Concomitant
Lymphadenopathy Other Serious 1/1/2003 60 Female 199 lb 3/29/2011 Consumer United States
Primary
Concomitant
Laryngitis Other Serious 1/1/2011 67 Female 139 lb 4/1/2011 Consumer Netherlands
Primary
Concomitant
Respiratory Disorder Other Serious 1/1/2010 28 Female 195 lb 4/20/2011 Consumer United States
Primary
Concomitant
Oedema Other Serious 1/20/2011 48 Female 172 lb 4/21/2011 Consumer Canada
Primary
Concomitant
Memory Impairment Other Serious 1/1/2008 47 Female 5/10/2011 Consumer Brazil
Primary
Concomitant
Pain Hospitalization 1/1/2010 63 Female 176 lb 5/17/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Pleurisy Hospitalization 5/12/2011 55 Female 161 lb 5/23/2011 Other Health Professional Greece
Primary
Secondary
Pleurisy Hospitalization 5/12/2011 55 Female 161 lb 6/8/2011 Physician Greece
Primary
Secondary
Pain Hospitalization 1/1/2010 63 Female 176 lb 6/15/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 3/14/2011 73 Female 6/16/2011 Physician Poland
Primary
Concomitant
Pleurisy Hospitalization 5/12/2011 55 Female 161 lb 6/27/2011 Physician Greece
Primary
Secondary
Lower Respiratory Tract Infection Other Serious 11/5/2010 54 Female 165 lb 6/29/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Macrocytosis Other Serious 45 Female 7/12/2011 Physician Spain
Primary
Concomitant
Basal Cell Carcinoma Other Serious 3/14/2011 73 Female 7/13/2011 Physician Poland
Primary
Concomitant
Rheumatoid Arthritis Death 2/19/2010 53 Female 165 lb 7/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 6/1/2011 72 Female 8/5/2011 Physician France
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 4/1/2010 68 Female 159 lb 8/26/2011 Physician New Zealand
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2008 65 Male 8/30/2011 Physician South Africa
Primary
Concomitant
Pleurisy Hospitalization 5/12/2011 55 Female 161 lb 9/6/2011 Physician Greece
Primary
Secondary
Respiratory Tract Infection Hospitalization 8/7/2011 56 Female 159 lb 9/29/2011 Physician United Kingdom
Primary
Concomitant
Costochondritis Hospitalization 8/7/2011 56 Female 159 lb 10/7/2011 Physician United Kingdom
Primary
Concomitant

Drug Data