Methotrexate combined with Singulair

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tongue Disorder Hospitalization 9/28/2005 75 Female 115 lb 11/19/2005 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/2/2006 Female 168 lb 2/10/2006 Consumer United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 12/7/2002 32 Female 170 lb 3/1/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/17/2001 68 Male 190 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Electrocardiogram Abnormal Other Serious 3/15/2006 Female 205 lb 3/21/2006 Other Health Professional United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death 8/20/2001 63 Female 198 lb 4/26/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2005 Female 4/27/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 60 Female 154 lb 4/27/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/17/2001 68 Male 190 lb 5/1/2006 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 12/7/2002 32 Female 170 lb 5/1/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2005 60 Female 5/11/2006 Other Health Professional United States
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 5/1/2006 Male 185 lb 5/25/2006 Consumer Canada
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 5/1/2006 Female 215 lb 6/9/2006 Physician United States
Primary
Concomitant
Burning Sensation 4/3/2006 62 Female 110 lb 6/30/2006 Consumer United States
Primary
Concomitant
Haemoptysis Other Serious 8/1/2004 46 Female 163 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Ratio Increased 1/1/2005 57 Female 201 lb 8/1/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 10/31/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Disorder Other Serious 12/1/2005 Female 9/26/2006 Consumer United States
Primary
Secondary
Concomitant
Heart Rate Increased 5/15/2006 55 Female 7/31/2006 Consumer United States
Primary
Concomitant
Skin Infection Hospitalization 5/1/2005 Female 305 lb 10/19/2006 Physician United States
Primary
Concomitant
Increased Upper Airway Secretion 4/1/2006 79 Male 10/30/2006 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/1/2006 Female 44 lb 10/31/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 3/9/2006 Female 190 lb 11/2/2006 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 10/1/2006 Female 147 lb 11/18/2006 Consumer United States
Primary
Concomitant
Skin Cancer Other Serious 3/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/26/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 7/1/2000 Female 132 lb 12/13/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/16/2006 Female 152 lb 12/13/2006 Physician United States
Primary
Concomitant
Injection Site Bruising 7/1/2006 Female 12/18/2006 Physician United States
Primary
Concomitant
Injection Site Reaction Other Serious 7/1/2005 65 Female 163 lb 11/30/2005 Consumer United States
Primary
Concomitant
Pain Other Serious 8/1/2005 56 Female 180 lb 12/5/2005 Other Health Professional United States
Primary
Concomitant
Spinal Column Stenosis Other Serious 11/1/2005 Female 183 lb 2/2/2007 Physician United States
Primary
Concomitant
Migraine Hospitalization 1/1/2004 Female 140 lb 2/6/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/1/2005 Female 183 lb 2/14/2007 Physician United States
Primary
Secondary
Concomitant
Vision Blurred 1/1/2005 66 Female 200 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Vasculitis Hospitalization 1/1/2006 68 Female 4/9/2007 Physician United States
Primary
Concomitant
Nervous System Disorder Other Serious 1/1/2007 Female 150 lb 4/13/2007 Other Health Professional United States
Primary
Concomitant
Vasculitis Hospitalization 1/1/2006 68 Female 4/18/2007 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 46 Female 5/18/2007 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 5/1/2005 Female 123 lb 5/29/2007 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 46 Female 6/13/2007 Consumer United States
Primary
Secondary
Concomitant
Cardiac Flutter Other Serious 3/1/2003 68 Female 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Fatigue 38 Female 249 lb 6/25/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 4/26/2007 57 Female 6/25/2007 Consumer United States
Primary
Concomitant
Swelling Other Serious 12/1/2006 Female 150 lb 6/26/2007 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 46 Female 7/11/2007 Consumer United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 Female 331 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 9/1/2006 Male 164 lb 7/27/2007 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2003 68 Female 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/27/2007 8 Male 44 lb 8/27/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 Female 331 lb 9/11/2007 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 76 Female 10/4/2007 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/1/2006 68 Female 10/23/2007 Physician United States
Primary
Concomitant
Menorrhagia Other Serious 1/1/2007 13 Female 10/30/2007 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 8/6/2007 54 Female 150 lb 11/9/2007 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 8/6/2007 54 Female 150 lb 11/20/2007 United States
Primary
Concomitant
Initial Insomnia 5/31/2007 59 Male 200 lb 11/8/2007 Consumer United States
Primary
Secondary
Concomitant
Menorrhagia Other Serious 3/1/2007 Female 156 lb 12/6/2007 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 4/3/2007 Female 12/6/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/15/2006 Female 200 lb 12/6/2007 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/1/2006 Female 12/7/2007 Physician
Primary
Concomitant
Nausea 1/1/2006 Female 12/10/2007 Physician United States
Primary
Concomitant
Sinusitis 1/1/2004 Male 229 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Psoriasis 1/1/2007 Female 12/15/2007 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 9/20/2007 60 Female 200 lb 12/5/2007 United States
Primary
Concomitant
Menorrhagia Other Serious 1/1/2007 Female 155 lb 12/26/2007 Other Health Professional United States
Primary
Concomitant
Angioedema Hospitalization 7/13/2007 44 12/27/2007 Pharmacist United States
Primary
Concomitant
Histoplasmosis Other Serious 12/1/2006 Female 231 lb 1/8/2008 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 9/20/2007 60 Female 200 lb 1/3/2008 United States
Primary
Concomitant
Vasculitis Hospitalization 1/1/2006 68 Female 2/5/2008 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 3/14/2005 68 Female 119 lb 2/15/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Required Intervention 9/20/2007 60 Female 200 lb 2/21/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Required Intervention 9/20/2007 60 Female 200 lb 2/29/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 Female 143 lb 3/25/2008 Physician United States
Primary
Concomitant
Asthma Other Serious 12/6/2007 Female 160 lb 3/26/2008 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 3/31/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 Female 143 lb 4/8/2008 Physician United States
Primary
Concomitant
Lactic Acidosis Life Threatening 12/29/2007 Male 243 lb 4/3/2008 Pharmacist United States
Primary
Secondary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 3/15/2008 15 Female 196 lb 4/29/2008 Pharmacist United States
Primary
Concomitant
Injection Site Pain 4/21/2008 Male 194 lb 6/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2007 Female 286 lb 6/13/2008 United States
Primary
Concomitant
Stomatitis 2/28/2008 63 Female 180 lb 6/18/2008 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2008 Female 7/2/2008 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Hospitalization Male 7/18/2008 Consumer United States
Primary
Concomitant
Metastasis Other Serious 67 Female 8/5/2008 United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 136 lb 8/25/2008 United States
Primary
Concomitant
Venoocclusive Disease Other Serious 3/31/2008 54 Male 164 lb 8/26/2008 Physician United States
Primary
Secondary
Concomitant
Traumatic Brain Injury Other Serious 11/7/2007 Female 234 lb 9/12/2008 Physician United States
Primary
Concomitant
Vomiting Life Threatening 61 Female 136 lb 9/8/2008 United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 11/12/2007 Male 275 lb 9/22/2008 Physician United States
Primary
Concomitant
Hallucination Other Serious 9/17/2008 Male 158 lb 10/1/2008 Consumer United States
Primary
Concomitant
Metastasis Other Serious 67 Female 158 lb 10/13/2008 United States
Primary
Concomitant
Weight Increased Other Serious 3/31/2008 54 Male 164 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 8/1/2006 Female 156 lb 10/27/2008 Consumer United States
Primary
Concomitant
Cholecystectomy Other Serious 10/1/2006 48 Female 291 lb 12/11/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/27/2007 8 Male 44 lb 12/9/2008 Physician Japan
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection 6/25/2007 Female 12/15/2008 Physician United States
Primary
Concomitant
Therapeutic Response Decreased 10/16/2007 Male 210 lb 12/15/2008 Physician United States
Primary
Concomitant
Tooth Disorder Hospitalization 8/1/2008 Female 2/17/2009 Consumer United States
Primary
Concomitant
Psoriasis Hospitalization Male 380 lb 2/20/2009 Consumer United States
Primary
Concomitant
Cholecystectomy Other Serious 10/1/2006 48 Female 291 lb 3/5/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/21/2009 Male 190 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Eye Disorder 75 Female 3/18/2009 Consumer United States
Primary
Concomitant
Presyncope Hospitalization 3/1/2009 33 Female 4/13/2009 Physician United States
Primary
Concomitant
Wheezing Other Serious 3/1/2009 Female 5/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea 4/2/2009 49 Female 5/15/2009 United States
Primary
Concomitant
Injection Site Swelling 6/30/2008 Female 160 lb 6/11/2009 Consumer United States
Primary
Concomitant
Accidental Exposure Male 172 lb 6/11/2009 Consumer United States
Primary
Concomitant
Pyrexia 11/10/2008 Female 6/11/2009 United States
Primary
Concomitant
Muscle Strain 1/1/2009 Male 180 lb 6/12/2009 Physician United States
Primary
Concomitant
Myalgia 1/1/2008 Male 210 lb 6/12/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Irritation 1/1/2005 Female 190 lb 6/12/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Female 295 lb 6/12/2009 United States
Primary
Concomitant
Urticaria 10/1/2008 Female 135 lb 6/12/2009 United States
Primary
Concomitant
Pruritus 5/28/2009 Female 6/12/2009 United States
Primary
Concomitant
Pleurisy Other Serious 10/29/2008 74 Female 194 lb 6/16/2009 Physician France
Primary
Concomitant
Insomnia 75 Female 6/19/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/27/2007 8 Male 44 lb 7/27/2009 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 10/13/2008 Female 254 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/1/2009 Female 156 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral 5/1/2009 48 Female 8/14/2009 Consumer United States
Primary
Concomitant
Unevaluable Event 1/1/2009 49 Female 8/14/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 10/13/2006 Female 115 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/13/2007 Female 231 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Swelling 6/30/2008 Female 160 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation Male 172 lb 9/12/2009 Consumer United States
Primary
Concomitant
Poor Quality Drug Administered Other Serious 3/4/2009 Male 185 lb 9/18/2009 United States
Primary
Concomitant
Vomiting Hospitalization 4/23/2006 Female 156 lb 9/19/2009 United States
Primary
Concomitant
Injection Site Pain 7/25/2009 Female 250 lb 9/19/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 4/1/2009 165 lb 9/19/2009 Consumer United States
Primary
Concomitant
Pruritus 7/6/2009 Female 165 lb 9/19/2009 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 1/1/2007 39 Female 10/12/2009 Physician Italy
Primary
Concomitant
Impaired Gastric Emptying Other Serious 2/24/2009 Female 10/20/2009 Physician United States
Primary
Concomitant
Aortic Aneurysm Hospitalization 2/8/2009 Male 206 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 1/1/2007 39 Female 10/26/2009 Physician Italy
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2009 49 Female 216 lb 11/3/2009 Other Health Professional Canada
Primary
Concomitant
Pruritus 8/23/2009 53 Female 10/20/2009 Consumer United States
Primary
Concomitant
Urticaria 3/1/2008 Female 226 lb 12/1/2009 Physician United States
Primary
Concomitant
Pleurisy Other Serious 10/29/2008 74 Female 194 lb 12/1/2009 Physician France
Primary
Concomitant
Injection Site Pain 1/2/2008 Female 233 lb 12/6/2009 Physician United States
Primary
Concomitant
Skin Infection 3/30/2008 Female 217 lb 12/8/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/18/2009 77 Female 12/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Histoplasmosis Hospitalization 10/1/2009 Male 222 lb 12/14/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/30/2007 25 Female 130 lb 11/9/2009 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/18/2009 77 Female 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/17/2009 Female 159 lb 1/29/2010 Other Health Professional Canada
Primary
Concomitant

Drug Data