Daunorubicin Hcl combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Steroid Withdrawal Syndrome Hospitalization 13 Male 1/27/2006 Physician United States
Primary
Concomitant
Tachycardia Death 2/1/2006 Male 42 lb 2/8/2006 United States
Primary
Secondary
Urinary Incontinence Hospitalization 4/1/1998 16 Male 2/15/2006 Physician Spain
Primary
Secondary
Concomitant
Pseudobulbar Palsy Other Serious 17 Male 3/1/2006 Physician Ireland
Primary
Concomitant
Urinary Incontinence Hospitalization 4/1/1998 16 Male 3/1/2006 Physician Spain
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/18/2006 14 Female 40 lb 3/2/2006 United States
Primary
Secondary
Urinary Incontinence Disability 18 Male 3/15/2006
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 48 Female 3/15/2006
Primary
Concomitant
Sepsis Other Serious 15 Male 3/17/2006 United States
Primary
Secondary
Concomitant
Polyuria Other Serious 13 Female 3/17/2006 United States
Primary
Concomitant
Respiratory Failure Hospitalization 3/14/2006 Male 251 lb 4/10/2006 United States
Primary
Secondary
Pyrexia Life Threatening 1/1/2006 69 Male 121 lb 4/20/2006 Consumer France
Primary
Concomitant
Pyrexia Life Threatening 1/1/2006 69 Male 121 lb 4/24/2006 Physician France
Primary
Concomitant
Pyrexia Life Threatening 1/1/2006 69 Male 121 lb 4/25/2006 Physician France
Primary
Concomitant
Urinary Incontinence Hospitalization 3/1/1997 16 Male 5/1/2006 Physician Spain
Primary
Secondary
Vith Nerve Paralysis Hospitalization 69 Female 5/19/2006 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 6/7/2006 Female 109 lb 6/8/2006 United States
Primary
Secondary
Ventricular Fibrillation Death 5/9/2006 11 Male 176 lb 6/11/2006 United States
Primary
Secondary
Haemorrhage Intracranial Hospitalization 6/7/2006 Female 109 lb 6/16/2006 United States
Primary
Secondary
Thrombocytopenia Hospitalization 7/2/2006 Male 9 lb 7/5/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 5/9/2006 Female 171 lb 7/7/2006 United States
Primary
Secondary
Convulsion Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Staphylococcal Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Enterobacter Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Bacterial Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Soft Tissue Disorder Required Intervention Unknown 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Required Intervention Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Pulmonary Mycosis Required Intervention 8 Female 7/25/2006 Consumer Israel
Primary
Secondary
Concomitant
Sinus Disorder Required Intervention 8 Female 7/25/2006 Israel
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 13 Female 7/31/2006 Physician Canada
Primary
Secondary
Thrombocytopenic Purpura Other Serious 10 Female 7/31/2006 Physician Canada
Primary
Secondary
White Blood Cell Count Increased Hospitalization 6/2/2006 Male 33 lb 8/11/2006 United States
Primary
Secondary
Vomiting Hospitalization 8/14/2006 Female 180 lb 8/15/2006 United States
Primary
Secondary
Concomitant
Vith Nerve Paralysis Hospitalization 69 Female 8/23/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Hospitalization 8/24/2006 10 Male 117 lb 8/25/2006 United States
Primary
Secondary
Urinary Incontinence Required Intervention 16 Male 9/1/2006 Other Health Professional Spain
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/2/2006 Male 33 lb 8/28/2006 United States
Primary
Secondary
Vomiting Hospitalization 8/14/2006 Female 180 lb 9/5/2006 United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/1/2006 Female 143 lb 9/15/2006 United States
Primary
Secondary
Urinary Incontinence Required Intervention 1/1/1997 16 Male 9/20/2006 Other Health Professional Spain
Primary
Concomitant
Septic Shock Hospitalization 9/1/2006 Female 188 lb 9/13/2006 Other Health Professional United States
Primary
Secondary
Therapy Non-responder Hospitalization 9/20/2006 Female 66 lb 9/22/2006 United States
Primary
Secondary
Fungal Infection Death 10/2/2006 Physician United States
Primary
Concomitant
Mucormycosis Death 10/2/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Required Intervention 40 Male 10/6/2006 United States
Primary
Secondary
Pyrexia Hospitalization 9/24/2006 Female 154 lb 10/11/2006 United States
Primary
Secondary
Mucormycosis Death 10/13/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 42 Female 10/27/2006 Physician Turkey
Primary
Secondary
Septic Shock Hospitalization 9/1/2006 Female 188 lb 10/26/2006 United States
Primary
Secondary
Prothrombin Time Prolonged Other Serious 10/25/2004 7 Male 11/13/2006
Primary
Secondary
Sepsis Hospitalization Female 87 lb 11/9/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/18/2006 Female 87 lb 12/13/2006 United States
Primary
Secondary
Concomitant
Vulval Erythema Hospitalization 12/10/2006 Female 138 lb 12/18/2006 United States
Primary
Secondary
Pancreatitis Other Serious 10/20/2006 17 Female 112 lb 12/18/2006 United Kingdom
Primary
Secondary
Concomitant
Vulval Disorder Hospitalization 12/10/2006 Female 138 lb 12/21/2006 United States
Primary
Secondary
Neurotoxicity Other Serious 7/4/2003 17 Female 10/7/2006 United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 43 Male 1/9/2007 Other Health Professional Spain
Primary
Concomitant
Splenic Infarction 12/22/2006 Female 42 lb 1/2/2007 United States
Primary
Secondary
Hepatotoxicity Other Serious 52 Male 1/19/2007 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 43 Male 1/19/2007 Other Health Professional Spain
Primary
Concomitant
Hepatotoxicity Other Serious 47 Female 1/19/2007 Other Health Professional Israel
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 52 Male 1/18/2007 Physician Israel
Primary
Secondary
Concomitant
Jaundice Cholestatic 52 Male 1/26/2007 Israel
Primary
Secondary
Concomitant
Hepatotoxicity 47 Female 1/26/2007 Israel
Primary
Secondary
Concomitant
Tracheal Haemorrhage 12/22/2006 Female 43 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Liver Disorder Other Serious 52 Male 2/7/2007 Israel
Primary
Secondary
Logorrhoea Hospitalization 12/21/2006 61 Female 2/23/2007 Consumer United States
Primary
Secondary
Jaundice Cholestatic Other Serious 52 Male 2/23/2007
Primary
Secondary
Hepatotoxicity Other Serious 47 Female 2/23/2007
Primary
Secondary
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
Logorrhoea Hospitalization 12/21/2006 61 Female 3/5/2007 Consumer United States
Primary
Secondary
Metastasis Death 11 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Female 3/5/2007
Primary
Secondary
Metastasis Death 13 Female 3/5/2007
Primary
Secondary
Metastasis Death 12 Male 3/5/2007
Primary
Secondary
Metastasis Death 19 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Male 3/5/2007
Primary
Secondary
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 6/1/2006 66 Female 2/27/2007 Japan
Primary
Secondary
Concomitant
Glioma Other Serious 2 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 2 Female 3/9/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 4 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 3 Female 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 5 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 2 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 2 Female 3/9/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 3 Female 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 4 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 5 Male 3/12/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 5 Male 3/12/2007 Consumer Finland
Primary
Secondary
Treatment Related Secondary Malignancy Death 11 Male 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 19 Male 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Male 3/1/2007 Germany
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 15 Female 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 12 Male 3/1/2007 Germany
Primary
Secondary
Glioma Death 13 Female 3/1/2007 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 3/7/2007 Female 66 lb 3/9/2007 United States
Primary
Secondary
Respiratory Failure Other Serious 2/1/2007 3/22/2007 Consumer Italy
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Male 3/16/2007 Germany
Primary
Secondary
Glioma Death 19 Male 3/16/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Female 3/16/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 12 Male 3/16/2007 Germany
Primary
Secondary
White Blood Cell Count Decreased Female 66 lb 3/20/2007 United States
Primary
Secondary
Glioma Death 13 Female 3/20/2007 Germany
Primary
Secondary
Glioma Death 11 Male 3/20/2007 Germany
Primary
Secondary
Neoplasm Malignant Death 15 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 13 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 11 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 15 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 12 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 66 Female 4/3/2007
Primary
Secondary
White Blood Cell Morphology Abnormal Other Serious 51 Female 3/29/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 66 Female 4/10/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 51 Female 5/8/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/23/2007 Female 256 lb 5/18/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/23/2007 Female 256 lb 6/1/2007 United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 22 Male 6/8/2007 Other Health Professional United States
Primary
Secondary
Cardiomyopathy Hospitalization 4/17/2007 8 Male 57 lb 6/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious Male 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious 22 Male 6/12/2007
Primary
Secondary
Hypertrophic Cardiomyopathy Hospitalization 4/17/2007 8 Male 5/31/2007 France
Primary
Secondary
Concomitant
Polyneuropathy Other Serious Female 6/22/2007
Primary
Secondary
Polyneuropathy Other Serious Male 6/22/2007
Primary
Secondary
Polyneuropathy Other Serious Female 7/5/2007
Primary
Secondary
Polyneuropathy Other Serious Male 7/5/2007
Primary
Secondary
Trichostasis Spinulosa Other Serious 6 Male 6/30/2007 Physician Australia
Primary
Secondary
Jaundice Hospitalization 7/5/2007 Female 61 lb 7/6/2007 United States
Primary
Secondary
Malignant Melanoma In Situ Other Serious Male 7/16/2007 United States
Primary
Secondary
Tachypnoea Hospitalization 3/15/2007 Female 183 lb 7/20/2007 United States
Primary
Secondary
Cerebellar Syndrome Hospitalization 5/21/2007 Male 8/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Mucoepidermoid Carcinoma Other Serious 1/20/2006 24 Female 8/3/2007 Consumer United States
Primary
Secondary
Vomiting Hospitalization 7/27/2007 Male 28 lb 7/27/2007 United States
Primary
Secondary
Vomiting Hospitalization 7/27/2007 Male 28 lb 8/7/2007 United States
Primary
Secondary
Unresponsive To Stimuli Other Serious 4 Female 8/11/2007 Physician United States
Primary
Secondary
Concomitant
Vasculitis Cerebral Other Serious 13 Male 8/11/2007 Physician United States
Primary
Secondary
Concomitant
Retinal Vein Thrombosis Hospitalization 4/21/2007 8 8/15/2007 Physician United States
Primary
Concomitant
Cerebellar Syndrome Death 5/21/2007 16 Male 8/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 8/25/2007 Female 169 lb 8/31/2007 United States
Primary
Secondary
Pseudomonas Infection Hospitalization 9/11/2007 Female 113 lb 9/12/2007 Other Health Professional United States
Primary
Secondary
Disease Recurrence Death 5 Male 9/10/2007 Argentina
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 9 Female 9/10/2007 Argentina
Primary
Secondary
Retinal Vein Thrombosis Hospitalization 4/21/2007 8 Male 9/19/2007 Physician United States
Primary
Concomitant
Pseudomonas Infection Hospitalization 9/11/2007 Female 113 lb 9/18/2007 Pharmacist United States
Primary
Secondary
Staphylococcal Infection Hospitalization 10/10/2007 Female 127 lb 10/12/2007 United States
Primary
Secondary
Depressed Level Of Consciousness 10/16/2007 Female 114 lb 10/22/2007 United States
Primary
Secondary
Concomitant

Drug Data