Methotrexate combined with Sodium Chloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Increased Tendency To Bruise 6/7/2006 47 Female 139 lb 10/2/2006 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 Female 331 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 12/18/2006 20 Male 115 lb 8/2/2007 Physician Japan
Primary
Concomitant
Tibia Fracture Hospitalization 4/1/2006 76 Female 8/14/2007 Germany
Primary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 Female 331 lb 9/11/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 11/25/2007 1 Male 23 lb 12/10/2007 Pharmacist United States
Primary
Concomitant
Altered State Of Consciousness Disability 11/20/2007 Female 104 lb 1/17/2008 Physician Japan
Primary
Concomitant
Altered State Of Consciousness Disability 11/20/2007 Female 104 lb 2/4/2008 Physician Japan
Primary
Concomitant
Somnolence Death 12/19/2007 Male 176 lb 2/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Altered State Of Consciousness Disability 11/20/2007 Female 104 lb 3/13/2008 Physician Japan
Primary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 168 lb 5/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 167 lb 4/25/2008 United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 167 lb 5/7/2008 United States
Primary
Secondary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Visual Impairment 4/1/2008 Female 250 lb 12/12/2008 United States
Primary
Concomitant
Glomerulonephritis Rapidly Progressive Other Serious 54 Female 249 lb 12/12/2008
Primary
Secondary
Concomitant
Vomiting Other Serious 64 Male 1/12/2009
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 64 Female 1/13/2009
Primary
Secondary
Concomitant
Vasodilatation Other Serious 1/25/2008 66 Male 1/13/2009 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2008 Female 3/14/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 60 Male 5/8/2009
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 69 Female 5/29/2009
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Salivary Gland Mass Other Serious 1/1/2008 38 Female 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 8/30/2009 Female 133 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 9/1/2008 Female 9/12/2009 Other Health Professional United States
Primary
Concomitant
Stomatitis Other Serious 8/13/2009 Female 133 lb 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2008 71 Female 179 lb 9/29/2009 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 9/25/2009 55 Male 10/19/2009 Pharmacist Ireland
Primary
Concomitant
Drug Interaction Hospitalization 10/6/2009 15 Male 11/5/2009 Physician France
Primary
Concomitant
Interacting
Stomatitis Other Serious 8/13/2009 Female 133 lb 11/11/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Life Threatening 3/9/2009 66 Female 115 lb 12/16/2009 Austria
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 10/4/2009 11 Female 81 lb 12/22/2009 Physician United States
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Screaming Hospitalization 10/4/2009 11 Female 81 lb 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Unintended Pregnancy Other Serious 9/13/2009 Female 200 lb 2/5/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Facial Paresis Hospitalization 9/2/2008 Male 159 lb 2/25/2010 Consumer United Kingdom
Primary
Concomitant
Hyperglycaemia 2/16/2010 Male 71 lb 2/25/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/10/2010 Male 130 lb 3/9/2010 Physician France
Primary
Concomitant
Organising Pneumonia Hospitalization 4/16/2009 Male 3/25/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 2/10/2010 34 Male 130 lb 4/19/2010 Physician France
Primary
Concomitant
Vomiting Other Serious 2/10/2010 34 Male 130 lb 4/21/2010 Physician France
Primary
Concomitant
Vomiting Other Serious 4/19/2010 77 Female 152 lb 4/30/2010 Pharmacist United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased 10/6/2009 15 Male 5/13/2010 Other Health Professional France
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 10/6/2009 15 Male 6/1/2010 Other Health Professional France
Primary
Concomitant
Interacting
Wound Other Serious Male 6/2/2010 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Wound Other Serious Male 6/14/2010 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Visual Impairment Hospitalization 4 Female 7/8/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 7/21/2010 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 4 Female 8/2/2010
Primary
Secondary
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Urticaria Other Serious 6/21/2010 27 Female 88 lb 8/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 8/11/2010 Physician Japan
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 59 Female 132 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 6/1/2009 59 Female 132 lb 9/1/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 8/10/2008 4 Male 26 lb 9/15/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 8/10/2008 4 Male 26 lb 10/27/2010 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/27/2010 52 Female 110 lb 10/29/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 10/8/2009 12 Male 92 lb 11/11/2010 Physician Japan
Primary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 10/10/2009 12 Male 92 lb 12/6/2010 Physician Japan
Primary
Concomitant
Urticaria Other Serious 6/21/2010 27 Female 88 lb 12/28/2010 Consumer United Kingdom
Primary
Concomitant
Depression Other Serious 10/30/2009 73 Female 110 lb 1/4/2011 Consumer Ireland
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 2/14/2008 17 Female 134 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 10/1/2010 70 Female 2/28/2011 Physician Ireland
Primary
Secondary
Concomitant
Intestinal Stenosis Other Serious 10/1/2010 70 Female 3/21/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Intestinal Stenosis Hospitalization 10/1/2010 70 Female 3/24/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Uterine Cyst Other Serious 10/1/2010 70 Female 4/7/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 9/16/2010 54 Female 131 lb 4/21/2011 Consumer United States
Primary
Concomitant
Stomatitis 4/20/2011 20 Female 188 lb 4/25/2011 United States
Primary
Secondary
Concomitant
Blood Urea Increased Other Serious 2/17/2011 52 Female 155 lb 4/12/2011 Physician Japan
Primary
Secondary
Concomitant
Tenderness Hospitalization 4/22/2011 20 Female 188 lb 4/27/2011 Physician United States
Primary
Secondary
Concomitant
Paralysis Flaccid Disability 41 Female 6/8/2011 Other Health Professional China
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 10/4/2009 6/14/2011 United States
Primary
Secondary
Concomitant
Product Quality Issue 3/16/2010 70 Female 6/17/2011 Consumer United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Infection Life Threatening 11/8/2009 15 Male 157 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Arrhythmia Life Threatening 2/14/2008 17 Female 134 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pericardial Effusion Life Threatening 10/10/2009 12 Male 92 lb 7/5/2011 Physician Japan
Primary
Concomitant
Paraesthesia Hospitalization 41 Female 7/25/2011 Other Health Professional China
Primary
Secondary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Cardiac Failure Life Threatening 2/14/2008 17 Female 134 lb 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Myositis Hospitalization 8/6/2011 11 Male 98 lb 8/23/2011 Physician United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 8/1/2010 73 Female 165 lb 8/26/2011 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Hy's Law Case Other Serious 1/25/2011 15 Male 115 lb 8/29/2011 Physician Thailand
Primary
Secondary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2011 11 Male 98 lb 9/2/2011 Physician United States
Primary
Secondary
Concomitant
Hy's Law Case Hospitalization 1/25/2011 15 Male 115 lb 9/21/2011 Physician Thailand
Primary
Secondary
Concomitant
Cardiovascular Disorder Hospitalization 9/1/2008 36 Female 9/22/2011 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 10/28/2011 79 Female 136 lb 11/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Disability 10/28/2011 79 Female 136 lb 11/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 10/28/2011 79 Female 136 lb 12/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Stomatitis Other Serious 8/13/2009 48 Female 133 lb 12/20/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization Female 269 lb 12/21/2011 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious Female 160 lb 1/4/2012 Lawyer United States
Primary
Concomitant
Urticaria Other Serious 11/15/2011 71 Female 123 lb 1/31/2012 Physician Japan
Primary
Concomitant
Fungal Infection Other Serious 3/22/2011 61 Female 2/6/2012 Physician Japan
Primary
Concomitant
Infection Hospitalization 1/29/2009 3 Female 35 lb 2/10/2012 Physician Japan
Primary
Concomitant
Flushing Other Serious 11/15/2011 71 Female 123 lb 2/21/2012 Physician Japan
Primary
Concomitant
Feeling Hot Other Serious 2/28/2012 55 Male 3/8/2012 Physician Canada
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/10/2011 49 Female 3/9/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 3/21/2012 20 Female 186 lb 3/23/2012 Physician United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma 8/1/2010 73 Female 165 lb 3/30/2012 Physician United States
Primary
Concomitant
Viral Haemorrhagic Cystitis Hospitalization 6 Male 42 lb 4/3/2012 Physician Japan
Primary
Concomitant
Hypoaesthesia Other Serious 16 Female 106 lb 4/2/2012 Pharmacist Canada
Primary
Concomitant
Anaphylactic Reaction Life Threatening 11 Male 4/5/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/1/2009 77 Female 4/19/2012 Consumer United States
Primary
Concomitant
Osteomyelitis Other Serious 2/24/2012 11 Female 116 lb 5/2/2012 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 4/7/2012 Female 162 lb 5/9/2012 Physician United States
Primary
Concomitant
Hypertension Death 2/24/2012 11 Female 116 lb 5/22/2012 Other Health Professional United States
Primary
Concomitant
Drug-induced Liver Injury Death 6/26/2009 11 Male 77 lb 5/25/2012 Physician Japan
Primary
Concomitant
Hypoproteinaemia Other Serious 6/26/2009 11 Male 77 lb 6/1/2012 Physician Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 4/7/2012 Female 162 lb 6/7/2012 Physician United States
Primary
Concomitant
Febrile Neutropenia Other Serious 3/18/2012 45 Female 6/11/2012 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Death Female 6/18/2012 Other Health Professional United Kingdom
Primary
Concomitant
Leukopenia Hospitalization 4/11/2012 65 Female 122 lb 7/5/2012 Physician Korea, Republic Of
Primary
Concomitant
Haemolytic Uraemic Syndrome Death 1/29/2009 3 Female 35 lb 7/5/2012 Physician Japan
Primary
Concomitant
Headache Hospitalization 5/1/2012 59 Female 136 lb 7/13/2012 Other Health Professional Canada
Primary
Concomitant
Pleural Effusion Other Serious 3/29/2012 70 Female 194 lb 8/1/2012 Physician United States
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/5/2008 8/15/2012 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/29/2012 70 Female 194 lb 8/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 4/11/2012 65 Female 122 lb 12/12/2012 Physician Kr
Primary
Concomitant
Urinary Tract Infection Other Serious 12/21/2011 70 Female 198 lb 10/11/2012 Physician Us
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/21/2011 70 Female 194 lb 10/3/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Skin Infection Hospitalization 2012 10 Female 99 lb 12/20/2012 Consumer Us
Primary
Secondary
Concomitant

Drug Data