Esomeprazole combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Other Serious 11/26/2005 66 Female 128 lb 12/30/2005 Switzerland
Primary
Secondary
Concomitant
Arthralgia Other Serious 2/1/2005 Female 214 lb 1/20/2006 United States
Primary
Concomitant
Femur Fracture Hospitalization 1/8/2006 Female 135 lb 1/26/2006 Canada
Primary
Concomitant
Trigeminal Neuralgia Hospitalization 9/2/2005 Female 1/30/2006 Denmark
Primary
Concomitant
Death Other Serious 6/20/2005 Male 2/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Trigeminal Neuralgia Hospitalization 9/2/2005 Female 2/10/2006 Denmark
Primary
Concomitant
Traumatic Fracture Other Serious 12/7/2005 Female 145 lb 2/16/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/18/2005 56 Female 2/22/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypersomnia Disability 11/21/2005 Female 93 lb 2/24/2006 France
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Other Serious 2/20/2006 Female 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Peritonitis Hospitalization 11/27/2004 Female 165 lb 4/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 4/14/2006 Norway
Primary
Concomitant
Injection Site Induration Hospitalization 11/1/2005 Female 130 lb 4/25/2006 Consumer United States
Primary
Concomitant
Peritonitis Hospitalization 11/27/2004 Female 165 lb 4/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 4/28/2006 Norway
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sinusitis Other Serious 10/31/2004 67 Female 124 lb 3/2/2006 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/26/2005 56 Female 248 lb 12/29/2005 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Reaction Hospitalization 4/13/2006 Female 141 lb 5/19/2006 Physician France
Primary
Concomitant
Therapy Non-responder Hospitalization 3/27/2006 Male 148 lb 7/7/2006 Norway
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 7/7/2006 Norway
Primary
Concomitant
Erosive Duodenitis Other Serious 2/8/2006 Female 128 lb 7/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 1/17/2007 10 Male 88 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Tooth Disorder Hospitalization 45 Female 154 lb 10/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Right Ventricular Failure Other Serious 3/1/2007 Male 161 lb 10/22/2007 Germany
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 3/1/2007 Male 11/9/2007 Physician Germany
Primary
Secondary
Concomitant
Gout Hospitalization Female 179 lb 11/16/2007 United Kingdom
Primary
Concomitant
Sepsis Death 6/30/2007 Female 123 lb 11/30/2007 United Kingdom
Primary
Concomitant
Pneumonia Death 5/17/2007 Male 112 lb 11/30/2007 United Kingdom
Primary
Concomitant
Neoplasm Other Serious 6/8/2007 Male 143 lb 12/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pericarditis Other Serious 60 Male 12/12/2007 Other Health Professional United States
Primary
Secondary
Oesophagitis Disability 77 Male 209 lb 12/12/2007 Physician United Kingdom
Primary
Concomitant
Diarrhoea Female 220 lb 12/20/2007 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 10/27/2006 Female 157 lb 12/28/2007 Germany
Primary
Concomitant
Vomiting Other Serious 6/27/2007 51 Female 1/7/2008 Consumer France
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 6/8/2007 66 Male 143 lb 1/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 6/30/2007 Female 123 lb 1/21/2008 United Kingdom
Primary
Concomitant
Cyst Hospitalization 8/22/2007 Female 209 lb 1/23/2008 United Kingdom
Primary
Concomitant
Rheumatoid Lung Other Serious 10/29/2004 Male 187 lb 1/25/2008 United Kingdom
Primary
Concomitant
Rheumatoid Lung Hospitalization 12/19/2004 Male 187 lb 1/25/2008 United Kingdom
Primary
Concomitant
Tooth Disorder Hospitalization 45 Female 154 lb 3/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Walking Aid User Other Serious 1/1/2007 Female 160 lb 3/21/2008 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death Female 148 lb 4/23/2008 United Kingdom
Primary
Concomitant
Anaphylactic Reaction Other Serious 3/31/2008 64 Male 5/13/2008 Physician
Primary
Concomitant
Wound Secretion Other Serious 10/27/2006 Female 157 lb 6/6/2008 Germany
Primary
Concomitant
Paraesthesia Hospitalization 2/14/2008 Female 6/9/2008 Germany
Primary
Concomitant
Goitre Hospitalization 11/30/2007 Female 8/5/2008 Consumer United Kingdom
Primary
Concomitant
Wound Secretion Other Serious 10/27/2006 Female 157 lb 8/6/2008 Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 Male 161 lb 8/8/2008 Germany
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death Female 148 lb 8/14/2008 United Kingdom
Primary
Concomitant
Constipation Hospitalization 3/10/2008 Female 9/5/2008 United States
Primary
Concomitant
Serotonin Syndrome Life Threatening 46 Female 9/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Cancer Hospitalization 11/30/2007 Female 9/11/2008 Consumer United Kingdom
Primary
Concomitant
Constipation Hospitalization 3/10/2008 Female 9/12/2008 United States
Primary
Concomitant
Pustular Psoriasis Other Serious Male 9/23/2008 Other Health Professional France
Primary
Secondary
Concomitant
Breast Cancer Life Threatening 1/26/2009 Female 3/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Thyroid Cancer Hospitalization 11/30/2007 Female 3/26/2009 Consumer United Kingdom
Primary
Concomitant
Breast Cancer Life Threatening 1/26/2009 Female 3/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Breast Cancer Life Threatening 1/26/2009 Female 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Breast Cancer Life Threatening 1/26/2009 Female 4/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 1/1/2009 47 Female 174 lb 6/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Femur Fracture Hospitalization 1/1/2004 61 Male 9/8/2009 Switzerland
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 3/1/2006 Female 130 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 1/24/2007 Male 175 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Rash 12/1/2006 Male 173 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 1/4/2007 Female 200 lb 9/11/2009 Consumer United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 3/13/2007 Female 130 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 1/30/2007 Male 165 lb 9/11/2009 Consumer United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 46 Female 9/9/2009 Physician United States
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 8/12/2009 Male 10/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 7/31/2009 Female 11/25/2009 Other Health Professional Italy
Primary
Concomitant
Femur Fracture Other Serious 1/1/2007 61 Female 11/30/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 12/21/2009 Physician Costa Rica
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 11/1/2009 Female 2/11/2010 Physician Australia
Primary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 Female 126 lb 3/3/2010 Physician Costa Rica
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 Female 126 lb 3/16/2010 Physician Costa Rica
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/24/2009 Female 181 lb 3/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 4/14/2009 51 Female 4/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death Female 4/6/2010 Physician United Kingdom
Primary
Concomitant
Headache Hospitalization 3/26/2010 25 Female 4/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Breast Cancer Life Threatening 1/26/2009 62 Female 148 lb 5/11/2010 Consumer France
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 5/1/2000 48 Female 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 48 Female 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 5/27/2010 6/7/2010 Physician France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 78 Female 6/18/2010 Physician France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 78 Female 6/24/2010 Physician France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 78 Female 6/24/2010 Physician France
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Hospitalization 10/17/2009 59 Male 171 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 6/28/2009 62 Female 6/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/1/2010 60 Male 126 lb 9/13/2010 Physician Serbia
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 78 Female 10/1/2010 Physician France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 76 Female 10/8/2010 Physician France
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/14/2010 67 Male 243 lb 10/13/2010 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 9/17/2010 62 Female 168 lb 10/13/2010 Pharmacist Australia
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2009 47 Female 10/18/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Life Threatening 9/1/2010 78 Male 194 lb 11/3/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization Female 11/3/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/11/2010 76 Female 137 lb 11/10/2010 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 9/28/2010 78 Male 194 lb 11/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 12/12/2006 64 Female 154 lb 11/9/2010 Physician Germany
Primary
Concomitant
Neurotoxicity Hospitalization 6/1/2007 56 Female 11/9/2010 Physician Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/1/2010 24 Male 227 lb 11/19/2010 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/11/2010 76 Female 137 lb 11/19/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/22/2010 Physician South Africa
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/24/2010 Physician South Africa
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/24/2010 Physician South Africa
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 76 Female 11/29/2010 Physician France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/13/2010 69 Female 128 lb 12/6/2010 Physician United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 5/11/2010 76 Female 137 lb 12/8/2010 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2009 47 Female 12/14/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 12/23/2010 Physician South Africa
Primary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 11/4/2010 63 Male 158 lb 1/18/2011 Physician South Africa
Primary
Concomitant
Anal Cancer Other Serious 2/1/2010 72 Female 139 lb 1/26/2011 Physician France
Primary
Secondary
Concomitant
Anal Cancer Other Serious 2/1/2010 72 Female 139 lb 1/27/2011 Physician France
Primary
Secondary
Concomitant
Pigmentation Disorder Hospitalization 1/8/2011 36 Female 2/8/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/1/2010 24 Male 227 lb 2/9/2011 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/17/2010 50 Male 159 lb 2/10/2011 Physician France
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 3/24/2009 58 Female 181 lb 3/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 1/1/2010 61 Female 3/11/2011 Physician Netherlands
Primary
Secondary
Concomitant
Bronchial Carcinoma Other Serious 2/6/2009 74 Female 3/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/16/2010 14 Female 130 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Discomfort Other Serious 3/3/2011 36 Female 3/29/2011 Consumer Netherlands
Primary
Concomitant
Abasia Other Serious 10 Female 4/18/2011 Physician South Africa
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/22/2009 67 Female 99 lb 4/21/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Histoplasmosis Disseminated Hospitalization 21 Male 4/22/2011 Physician United States
Primary
Concomitant
Anxiety Other Serious 3/3/2011 36 Female 159 lb 4/26/2011 Consumer Netherlands
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/22/2009 67 Female 99 lb 4/26/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Contusion Female 11/6/2011 Physician United States
Primary
Concomitant
Sepsis Hospitalization 11/4/2010 63 Male 158 lb 11/11/2011 Physician South Africa
Primary
Concomitant
Body Temperature Fluctuation Hospitalization 9/8/2011 55 Male 168 lb 12/1/2011 Consumer Netherlands
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 5/17/2010 50 Male 159 lb 1/25/2012 Physician France
Primary
Secondary
Concomitant
Ischaemic Cerebral Infarction Disability 1/11/2012 64 Female 148 lb 2/16/2012 Physician Australia
Primary
Concomitant
Thrombotic Stroke Hospitalization 1/11/2012 64 Female 148 lb 2/21/2012 Physician Australia
Primary
Concomitant
Colitis Hospitalization 12/9/2011 45 Female 3/28/2012 Physician France
Primary
Concomitant
Juvenile Arthritis Hospitalization 3/15/2012 18 Female 148 lb 3/29/2012 Physician Germany
Primary
Secondary
Concomitant
Cellulitis Hospitalization 1/1/2009 69 Male 179 lb 4/5/2012 Other Health Professional United Kingdom
Primary
Concomitant
Neuroendocrine Carcinoma Of The Skin Hospitalization 10/1/2010 54 Female 4/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data