Januvia combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Blood Creatinine Increased 69 Male 5/17/2007 Physician United States
Primary
Concomitant
Dizziness 5/1/2007 8/16/2007 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2005 67 Male 229 lb 11/9/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral 11/10/2007 Female 230 lb 12/15/2007 United States
Primary
Concomitant
Underdose 1/1/2004 Male 241 lb 12/15/2007 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 12/19/2007 72 Female 150 lb 2/6/2008 Physician United States
Primary
Concomitant
Blood Glucose Increased 1/1/2007 74 Male 2/15/2008 United States
Primary
Concomitant
Injection Site Swelling 11/21/2007 Female 250 lb 3/14/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Disability 1/1/2008 69 Female 6/26/2008 Physician United States
Primary
Concomitant
Rash Macular 6/23/2007 80 Female 182 lb 11/14/2008 Physician United States
Primary
Concomitant
Venous Occlusion Other Serious Female 3/17/2009 Physician Puerto Rico
Primary
Concomitant
Pancreatitis Death 11/1/2008 Male 3/23/2009 Consumer United States
Primary
Concomitant
Weight Decreased Life Threatening 2/5/2009 51 NotSpecified 150 lb 4/3/2009 United States
Primary
Concomitant
Weight Decreased Life Threatening 2/5/2009 51 Male 150 lb 4/20/2009 United States
Primary
Concomitant
Dyspnoea 4/2/2009 49 Female 5/15/2009 United States
Primary
Concomitant
White Blood Cell Count Increased 3/1/2009 Male 225 lb 6/12/2009 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/12/2009 45 Female 258 lb 6/15/2009 Physician United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 11/1/2008 Female 256 lb 8/18/2009 Consumer United States
Primary
Concomitant
Blood Glucose Increased 4/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Oedema Peripheral 5/1/2009 48 Female 8/14/2009 Consumer United States
Primary
Concomitant
Unevaluable Event 1/1/2009 49 Female 8/14/2009 Consumer United States
Primary
Concomitant
Injection Site Swelling 11/21/2007 Female 250 lb 9/12/2009 Consumer United States
Primary
Concomitant
Drug Ineffective Female 9/19/2009 Consumer Puerto Rico
Primary
Concomitant
Sigmoiditis Other Serious 5/6/2009 58 Male 10/13/2009 Physician France
Primary
Concomitant
Thyroid Cancer Other Serious 8/4/2009 Female 10/14/2009 Physician United States
Primary
Concomitant
Acute Hepatic Failure Life Threatening 9/29/2009 Male 184 lb 10/16/2009 Pharmacist United States
Primary
Concomitant
Alopecia 7/10/2009 91 Female 11/16/2009 United States
Primary
Concomitant
Palpitations 6/1/2009 76 Male 113 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Drug Effect Decreased 11/1/2008 Female 144 lb 1/29/2010 Physician United States
Primary
Concomitant
Vertigo 9/15/2009 Female 116 lb 1/29/2010 Consumer United States
Primary
Concomitant
Hypoglycaemia 85 Female 185 lb 1/30/2010 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 2/1/2010 88 Female 2/19/2010 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 9/11/2009 56 Female 2/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 2/1/2010 88 Female 2/24/2010 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization 1/23/2010 80 Female 3/12/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 3/1/2009 Female 214 lb 3/17/2010 Physician United States
Primary
Concomitant
Myalgia Other Serious 67 Male 6/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 5/28/2010 65 Female 210 lb 6/10/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/12/2009 46 Female 258 lb 6/14/2010 United States
Primary
Concomitant
Psoriasis Hospitalization 5/28/2010 65 Female 210 lb 6/24/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 4/1/2010 67 Female 7/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Secondary Adrenocortical Insufficiency Hospitalization 3/1/2010 67 Male 7/28/2010 Physician France
Primary
Secondary
Concomitant
Psoriasis Hospitalization 5/28/2010 65 Female 210 lb 8/11/2010 Physician United States
Primary
Concomitant
Swelling Female 250 lb 8/28/2010 United States
Primary
Concomitant
Rash Other Serious 3/20/2008 57 Female 10/11/2010 Physician United States
Primary
Concomitant
Skin Discolouration Hospitalization 10/20/2010 66 Female 12/7/2010 Consumer Colombia
Primary
Concomitant
Somnolence 12/23/2010 Consumer United States
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 1/23/2010 80 Female 12/31/2010 Physician Japan
Primary
Concomitant
Anaemia Other Serious 12/11/2010 60 Female 222 lb 1/19/2011 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 10/20/2010 66 Female 1/28/2011 Consumer Colombia
Primary
Concomitant
Myalgia Other Serious 67 Male 1/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Glucose Increased Hospitalization 5/9/2010 67 Male 1/28/2011 Pharmacist United Kingdom
Primary
Concomitant
Eye Discharge 4/18/2010 55 Female 263 lb 1/28/2011 Consumer United States
Primary
Concomitant
Hyperaesthesia Female 1/28/2011 Pharmacist United States
Primary
Concomitant
Urticaria 6/14/2010 49 Female 1/29/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 7/14/2010 57 Female 1/30/2011 Consumer United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased 8/1/2010 59 Female 152 lb 1/30/2011 Consumer United States
Primary
Concomitant
Depression 10/1/2010 74 Female 185 lb 1/30/2011 Consumer United States
Primary
Concomitant
Dependence On Respirator Hospitalization 2/1/2010 66 Male 2/25/2011 Other Health Professional United States
Primary
Concomitant
Malaise 69 Female 3/8/2011 Consumer United States
Primary
Concomitant
Tracheostomy Hospitalization 2/1/2010 66 Male 223 lb 3/24/2011 Physician United States
Primary
Concomitant
Crohn's Disease Hospitalization 1/1/2011 58 Male 5/12/2011 Physician France
Primary
Concomitant
Crohn's Disease Hospitalization 1/1/2011 58 Male 5/13/2011 Physician France
Primary
Concomitant
Carotid Artery Occlusion Hospitalization 1/1/2010 63 Female 197 lb 5/25/2011 Consumer United States
Primary
Concomitant
Alopecia 47 Male 179 lb 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Injury Other Serious 7/1/2003 42 Female 200 lb 6/9/2011 Consumer United States
Primary
Concomitant
Drug Ineffective 4/1/2011 74 Male 201 lb 6/13/2011 Pharmacist United States
Primary
Secondary
Concomitant
Dyskinesia Other Serious 4/1/2011 74 Male 201 lb 6/13/2011 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 6/20/2011 60 Male 190 lb 7/5/2011 Physician Australia
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 1/23/2010 80 Female 7/28/2011 Physician Japan
Primary
Concomitant
Erythema 4/8/2011 44 Female 390 lb 8/6/2011 Consumer United States
Primary
Concomitant
Anxiety 2/10/2011 69 Female 9/6/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 1/1/2011 46 Female 254 lb 9/19/2011 Consumer United States
Primary
Concomitant
Interacting
Fatigue Hospitalization 1/1/2011 46 Female 254 lb 9/20/2011 Physician United States
Primary
Concomitant
Interacting
Fibromyalgia Hospitalization 8/1/2011 61 Female 144 lb 10/19/2011 Consumer United States
Primary
Secondary
Concomitant
Odynophagia 72 Male 10/24/2011 Consumer United States
Primary
Concomitant
Muscular Weakness 2/27/2011 72 Male 174 lb 11/3/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 2/10/2011 69 Female 11/6/2011 Consumer United States
Primary
Secondary
Concomitant
Injection Site Rash 8/15/2011 62 Male 212 lb 11/6/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission Hospitalization 12/1/2010 60 Female 12/7/2011 Consumer United States
Primary
Concomitant
Flank Pain Other Serious 8/1/2011 57 Female 1/3/2012 Physician France
Primary
Concomitant
Pain Hospitalization 36 Female 165 lb 1/13/2012 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2011 77 Female 250 lb 1/23/2012 Physician United States
Primary
Concomitant
Joint Stiffness 5/1/2011 40 Female 180 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Nodule Female 207 lb 1/28/2012 Consumer United States
Primary
Concomitant
Hot Flush 3/1/2011 45 Female 238 lb 1/28/2012 Consumer United States
Primary
Concomitant
Psoriasis 6/1/2010 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pruritus 9/12/2011 64 Female 185 lb 1/28/2012 Consumer United States
Primary
Concomitant
Rash Papular 11/1/2011 66 Female 1/29/2012 Consumer United States
Primary
Concomitant
Arthralgia 12/1/2011 48 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 12/20/2011 48 Female 1/29/2012 Consumer United States
Primary
Concomitant
Joint Swelling 1/1/2010 52 Female 157 lb 1/29/2012 Consumer United States
Primary
Concomitant
Muscle Spasms 3/1/2011 55 Female 237 lb 1/28/2012 Consumer United States
Primary
Concomitant
Chest Pain Other Serious 1/1/2011 59 Female 1/28/2012 Consumer United States
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2011 77 Female 250 lb 2/14/2012 Physician United States
Primary
Concomitant
Bipolar I Disorder Other Serious 1/20/2011 39 Male 267 lb 2/15/2012 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/31/2012 72 Female 198 lb 2/17/2012 Physician United States
Primary
Concomitant
Blood Cholesterol Increased Other Serious 1/20/2011 39 Male 267 lb 2/21/2012 Consumer United States
Primary
Concomitant
Hypersensitivity Hospitalization 2/1/2010 36 Female 2/24/2012 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2011 71 Female 198 lb 2/27/2012 Physician United States
Primary
Concomitant
Cough Hospitalization 1/1/2012 72 Female 198 lb 2/28/2012 Physician United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization 1/1/2011 68 Female 3/5/2012 Consumer Colombia
Primary
Concomitant
Blood Sodium Decreased Hospitalization 10/28/2011 68 Female 3/15/2012 Consumer Colombia
Primary
Concomitant
Cellulitis Hospitalization 7/4/2011 71 Female 190 lb 3/29/2012 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 10/1/2011 57 Female 256 lb 4/4/2012 Consumer United States
Primary
Concomitant
Balance Disorder Other Serious Female 148 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 4/16/2012 74 Female 4/25/2012 Physician United States
Primary
Concomitant
Angioedema Hospitalization 4/16/2012 74 Female 5/15/2012 Physician United States
Primary
Concomitant
Ovarian Cyst Other Serious 10/1/2011 43 Female 196 lb 5/16/2012 Consumer Puerto Rico
Primary
Concomitant
Pain 7/1/2003 42 Female 200 lb 5/17/2012 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2008 59 Female 180 lb 5/18/2012 Consumer United States
Primary
Concomitant
Joint Injury 7/1/2003 50 Female 200 lb 5/31/2012 Consumer United States
Primary
Concomitant
Ovarian Cyst Other Serious 10/1/2011 43 Female 196 lb 5/31/2012 Consumer Puerto Rico
Primary
Concomitant
Malaise Hospitalization 4/2/2012 77 Female 6/6/2012 Other Health Professional France
Primary
Concomitant
Renal Disorder Other Serious 4/5/2012 77 Male 101 lb 6/28/2012 Physician Japan
Primary
Concomitant
Death Death 4/8/2012 56 Male 7/12/2012 Physician Japan
Primary
Concomitant
Cardiac Disorder Hospitalization 7/2/2012 64 Female 7/13/2012 Pharmacist United States
Primary
Concomitant
Chills Other Serious 1/1/2008 59 Female 180 lb 7/13/2012 Consumer United States
Primary
Concomitant
Ovarian Cyst Hospitalization 10/1/2011 43 Female 196 lb 7/18/2012 Consumer Puerto Rico
Primary
Concomitant
Haemorrhagic Cyst Hospitalization 10/1/2011 43 Female 196 lb 8/9/2012 Consumer Puerto Rico
Primary
Concomitant
Renal Disorder Other Serious 4/5/2012 77 Male 101 lb 8/9/2012 Physician Japan
Primary
Concomitant
Injection Site Haemorrhage 12/2011 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 2011 65 Male 172 lb 9/17/2012 Consumer Us
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/2011 Female 196 lb 12/7/2012 Consumer Pr
Primary
Concomitant
Wrong Technique In Drug Usage Process 61 Female 10/23/2012 Physician Us
Primary
Concomitant
Rash Generalised Other Serious 6/6/2012 62 Male 163 lb 2/11/2013 Physician Jp
Primary
Secondary
Concomitant
Influenza Like Illness 11/16/2011 56 Male 270 lb 10/25/2012 Physician Us
Primary
Concomitant
Injection Site Pruritus 3/2/2012 65 Female 315 lb 10/25/2012 Physician Us
Primary
Concomitant
Sepsis Other Serious Female 11/7/2012 Physician Us
Primary
Concomitant
Rash Pruritic Female 11/7/2012 Physician Us
Primary
Concomitant
Contusion 3/30/2012 60 Male 11/8/2012 Other Health Professional Us
Primary
Concomitant
Oral Disorder Other Serious 75 Female 11/30/2012 Physician Us
Primary
Concomitant
Lethargy 3/22/2012 57 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Temperature Intolerance Female 139 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Local Swelling 10/2011 44 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Pneumonia Hospitalization 11/2010 Female 265 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Gallbladder Disorder 1/2012 Female 198 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Swelling Other Serious 2009 77 Male 1/28/2013 Physician Country Not Specified
Primary
Concomitant
Psoriatic Arthropathy 53 Male 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Pain 6/15/2012 85 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Viral Infection 10/2012 85 Female 1/31/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Injection Site Pain 10/4/2012 58 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Pain In Extremity 2/2012 67 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Unevaluable Event 2/2012 65 Female 1/31/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 2/2012 Female 154 lb 1/29/2013 Physician Country Not Specified
Primary
Concomitant
Injection Site Pain 6/18/2012 64 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Urticaria Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Portal Hypertension Death 2/2012 Male 325 lb 2/15/2013 Consumer Us
Primary
Concomitant
Pyrexia 4/4/2012 62 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant

Drug Data