Methotrexate combined with Promethazine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Hospitalization 4/29/2001 55 Female 148 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/19/2002 41 Female 150 lb 3/1/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/6/2006 85 Male 137 lb 2/6/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/1/2001 41 Female 150 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Muscle Spasms Hospitalization 11/17/1999 41 Female 154 lb 4/10/2006 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/13/2003 56 Female 181 lb 4/14/2006 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2002 52 Female 121 lb 4/24/2006 Physician United States
Primary
Concomitant
Myalgia Other Serious 51 Female 4/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2003 37 Female 6/28/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2003 37 Female 6/22/2006 Physician United States
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 7/30/2006 57 Male 149 lb 8/10/2006 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 9/25/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 9/29/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 8/26/2006 Female 11/10/2006 Physician United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 8/26/2006 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 21 Female 8/16/2007 Physician United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
Injection Site Pain 1/1/2004 Female 170 lb 12/14/2007 Consumer
Primary
Concomitant
Headache 3/20/2007 Female 185 lb 3/14/2008 Physician United States
Primary
Concomitant
Overdose 3/17/2008 Female 232 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 11/12/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Overdose 3/17/2008 Female 232 lb 9/13/2008 Pharmacist United States
Primary
Concomitant
Sudden Death Death 9/9/2008 Female 9/19/2008 United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2008 Male 200 lb 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 10/16/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 166 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Wheezing Other Serious 6/6/2008 Female 237 lb 11/21/2008 Consumer United States
Primary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Inflammation Hospitalization 11/1/2008 Male 90 lb 11/18/2008 United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 11/12/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 67 Male 4/9/2009
Primary
Secondary
Non-small Cell Lung Cancer Other Serious 4/17/2009 Female 126 lb 6/5/2009 United States
Primary
Concomitant
Vomiting Hospitalization 6/8/2009 Female 169 lb 6/12/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Death 91 Female 126 lb 6/18/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 6/8/2009 Female 169 lb 7/1/2009 United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 83 Female 170 lb 7/2/2009 United States
Primary
Concomitant
Histoplasmosis Disseminated Other Serious 5/7/2008 Male 226 lb 8/13/2009 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 6/1/2009 Female 134 lb 9/3/2009 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Death Male 8/31/2009 United States
Primary
Concomitant
Incorrect Dose Administered 3/30/2007 Female 130 lb 9/11/2009 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iiib Other Serious 4/17/2009 Female 126 lb 9/18/2009 United States
Primary
Concomitant
Wound Haemorrhage 4/1/2009 Female 9/19/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Nausea Other Serious 1/1/2009 Female 144 lb 10/6/2009 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/7/2009 43 Female 201 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 7/7/2009 Male 10/14/2009 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Sinusitis Hospitalization 11/2/2009 49 Female 11/20/2009 Consumer South Africa
Primary
Secondary
Concomitant
Latex Allergy Female 12/3/2009 Pharmacist
Primary
Concomitant
Sinusitis Hospitalization 11/2/2009 49 Female 12/8/2009 Other Health Professional South Africa
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 7/7/2009 Male 1/26/2010 Physician United Kingdom
Primary
Concomitant
Injection Site Pain 6/1/2009 Female 147 lb 1/30/2010 United States
Primary
Concomitant
Sinusitis Hospitalization 11/2/2009 49 Female 2/7/2010 Other Health Professional South Africa
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 10/1/2009 Female 3/1/2010 Consumer United States
Primary
Concomitant
Pain In Extremity 1/1/2009 Female 185 lb 2/10/2010 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 11/2/2009 49 Female 3/11/2010 Other Health Professional South Africa
Primary
Secondary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 Male 3/18/2010 Physician United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 Male 3/24/2010 Physician United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 5/7/2010 United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 5/27/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 6/2/2010 Other Health Professional Australia
Primary
Concomitant
Urinary Tract Infection Other Serious Female 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 7/16/2010 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 7/5/2010 52 Female 203 lb 7/13/2010 Other Health Professional Australia
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 1/17/2010 64 Female 141 lb 7/19/2010 Other Health Professional Germany
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 7/5/2010 52 Female 203 lb 7/22/2010 Other Health Professional Australia
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 7/30/2010 Physician United States
Primary
Concomitant
Respiratory Distress Other Serious 7/5/2010 52 Female 203 lb 7/28/2010 Other Health Professional Australia
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 8/6/2010 Physician United States
Primary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/7/2010 54 Female 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 1/17/2010 64 Female 141 lb 8/19/2010 Consumer Germany
Primary
Concomitant
Pneumonia Other Serious 10/1/2009 60 Female 9/3/2010 Physician United States
Primary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/17/2010 39 Female 9/10/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2009 50 Female 249 lb 9/16/2010 Physician United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 9/17/2010 Physician United States
Primary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 9/24/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/7/2010 54 Female 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Other Serious 2/27/2009 21 Female 190 lb 10/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Other Serious 2/27/2009 21 Female 190 lb 10/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 10/14/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/10/2009 55 Female 185 lb 10/14/2010 Consumer Brazil
Primary
Concomitant
Visual Impairment Other Serious 4/10/2009 55 Female 185 lb 10/15/2010 Consumer Brazil
Primary
Concomitant
Hypotension Hospitalization 8/23/2010 50 Female 11/5/2010 Physician Switzerland
Primary
Concomitant
Upper-airway Cough Syndrome Hospitalization 1/31/2010 53 Female 218 lb 10/27/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 9/11/2009 11/30/2010 Physician United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Life Threatening 11/16/2010 14 Female 130 lb 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 11/16/2010 14 Female 130 lb 12/17/2010 Physician United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Female 132 lb 11/5/2010 Consumer United States
Primary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 12/22/2010 United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 10/8/2010 41 Female 12/23/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 11/16/2010 14 Female 130 lb 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/8/2010 67 Male 159 lb 12/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 11/17/2010 53 Female 203 lb 12/15/2010 Australia
Primary
Concomitant
Blood Bilirubin Increased Life Threatening 11/16/2010 14 Female 130 lb 1/5/2011 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/27/2009 20 Female 190 lb 1/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Diarrhoea Female 190 lb 1/28/2011 United States
Primary
Concomitant
Arthralgia 9/5/2010 53 Female 1/29/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio 9/4/2010 50 Female 1/30/2011 Consumer United States
Primary
Concomitant
Chest Pain 1/1/2009 40 Female 170 lb 1/30/2011 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Hospitalization 9/10/2010 65 Female 106 lb 1/31/2011 Physician United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 107 lb 2/2/2011 Physician United States
Primary
Secondary
Concomitant
Drug Screen Positive Hospitalization 9/10/2010 65 Female 106 lb 2/3/2011 Physician United States
Primary
Concomitant
Injection Site Swelling Hospitalization 1/14/2011 29 Female 190 lb 2/7/2011 Consumer United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 107 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Consolidation Hospitalization 11/17/2010 53 Female 203 lb 2/22/2011 Other Health Professional Australia
Primary
Concomitant
Deep Vein Thrombosis Death 1/1/2010 61 Female 3/11/2011 Physician Netherlands
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 106 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/16/2010 14 Female 130 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 8/4/2010 13 Female 99 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Fluid Retention Other Serious 10/1/2009 60 Female 4/15/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization Female 4/20/2011 Physician United States
Primary
Concomitant
Abdominal Pain Female 375 lb 2/7/2011 Other Health Professional United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/7/2010 61 Female 6/10/2011 Physician Netherlands
Primary
Secondary
Concomitant
Joint Stiffness Disability 1/1/2010 68 Female 6/15/2011 Physician United States
Primary
Concomitant
Drug Dose Omission Hospitalization 1/1/2010 62 Female 6/27/2011 Consumer United States
Primary
Concomitant
Blister 4/21/2011 61 Female 158 lb 7/5/2011 Consumer United States
Primary
Concomitant
Alopecia Other Serious 10/7/2002 77 Female 192 lb 7/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hand Fracture Hospitalization 1/1/2010 62 Female 7/8/2011 Consumer United States
Primary
Concomitant
Joint Stiffness Disability 1/1/2010 67 Female 164 lb 7/14/2011 Physician United States
Primary
Concomitant
Hyperbilirubinaemia Death 5/31/2011 23 Male 306 lb 8/3/2011 Pharmacist United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Night Sweats Other Serious 11/29/2006 47 Female 160 lb 8/8/2011 Physician United States
Primary
Secondary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Skin Lesion Other Serious 4/10/2009 55 Female 176 lb 8/11/2011 Consumer Brazil
Primary
Concomitant
Hepatic Failure Hospitalization 6/16/2011 23 Male 307 lb 8/18/2011 Physician United States
Primary
Secondary
Concomitant
Candidiasis Other Serious 5/1/2009 44 Female 156 lb 8/26/2011 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization 7/16/2011 43 Female 9/2/2011 Consumer United States
Primary
Concomitant
Influenza Like Illness 5/1/2011 69 Female 9/6/2011 Consumer United States
Primary
Concomitant
Throat Irritation Hospitalization 8/4/2011 10 Female 75 lb 8/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Accidental Overdose Death 48 Female 247 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Abuse Death 48 Female 247 lb 9/14/2011 Physician United States
Primary
Secondary
Concomitant
Chest Injury Other Serious 1/1/2010 62 Female 9/12/2011 Consumer United States
Primary
Concomitant
Skin Lesion Other Serious 4/10/2009 55 Female 176 lb 9/19/2011 Consumer Brazil
Primary
Concomitant
Iatrogenic Injury Other Serious 6/4/2010 45 Female 246 lb 10/4/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data