Daunorubicin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 6 Male 1/6/2006 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention Female 1/23/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/22/2005 Female 138 lb 1/23/2006 United States
Primary
Secondary
Respiratory Disorder Other Serious 17 Male 2/2/2006 Other Health Professional Ireland
Primary
Secondary
Pseudobulbar Palsy Other Serious 17 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 6 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 10 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Vith Nerve Paralysis Hospitalization 69 Female 5/5/2006 Physician United States
Primary
Concomitant
Pulmonary Infarction Other Serious 12/10/2005 Male 178 lb 5/9/2006 United States
Primary
Secondary
Precocious Puberty Other Serious Female 9/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 19 Male 9/26/2007 Other Health Professional Spain
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 4 Female 10/10/2007
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 13 Male 10/10/2007
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 4 Female 10/11/2007 Other Health Professional United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 13 Male 10/11/2007 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Death 8/20/2006 8 Male 10/9/2007 United Kingdom
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 13 Male 10/4/2007 Other Health Professional United States
Primary
Secondary
Renal Impairment Life Threatening 9/27/2007 Male 187 lb 10/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Glioblastoma Other Serious 6 Male 11/20/2007 Other Health Professional India
Primary
Secondary
Vomiting Death 3/1/2004 4 Female 11/20/2007
Primary
Secondary
Concomitant
Glioblastoma Multiforme Other Serious 6 Male 11/20/2007
Primary
Secondary
Hemiparesis Other Serious 10 Male 11/20/2007
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 65 Female 11/26/2007 Other Health Professional United States
Primary
Secondary
Malignant Neoplasm Progression Other Serious 4 Female 11/26/2007 Other Health Professional India
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/25/2008 United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 9 Male 7/31/2008 Physician India
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 11 Female 7/31/2008 Physician India
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 0 Female 11/18/2008 Other Health Professional United States
Primary
Secondary
Inflammation Hospitalization 11/1/2008 Male 90 lb 11/18/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/13/2008 Female 12 lb 11/25/2008 United States
Primary
Secondary
Pyrexia Hospitalization 12/6/2008 Female 18 lb 12/8/2008 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 51 Female 1/20/2009 Greece
Primary
Secondary
Skin Ulcer Hospitalization 11/11/2008 1 Male 24 lb 3/24/2009 Physician
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 7/14/2009 Male 214 lb 8/5/2009 United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 2 Female 11/24/2009 United Kingdom
Primary
Secondary
Concomitant
Lymphopenia Other Serious 4/29/2009 4 Male 12/14/2009 Physician
Primary
Secondary
Neurotoxicity Hospitalization 17 Male 12/16/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 12/7/2009 17 Male 146 lb 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/10/2010 Male 130 lb 3/9/2010 Physician France
Primary
Concomitant
Oesophageal Stenosis Hospitalization 11 Male 4/19/2010 Physician Ireland
Primary
Secondary
Oesophageal Stenosis Hospitalization 1 Male 4/19/2010 Physician Ireland
Primary
Secondary
Weight Decreased Hospitalization 4 Male 4/19/2010 Physician Ireland
Primary
Secondary
Oesophageal Stenosis Hospitalization 2 Female 4/19/2010 Physician Ireland
Primary
Secondary
Incorrect Dose Administered 9/24/2010 16 Male 130 lb 10/14/2010 United States
Primary
Secondary
Blood Glucose Increased 9/17/2010 20 Female 95 lb 11/3/2010 United States
Primary
Secondary
Neutrophil Count Abnormal 3/5/2010 2 Male 24 lb 11/4/2010 United States
Primary
Secondary
Therapeutic Response Decreased Hospitalization 5/1/2008 27 Male 11/30/2010
Primary
Secondary
Petechiae Death 6/15/2010 75 Male 153 lb 11/29/2010 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 10/29/2010 12 Female 112 lb 11/29/2010 United States
Primary
Secondary
Diabetes Mellitus Hospitalization 8/1/2008 30 Female 12/9/2010 Physician United Kingdom
Primary
Secondary
Pain In Extremity Hospitalization 1/28/2010 19 Male 349 lb 12/16/2010 United States
Primary
Secondary
Subclavian Vein Thrombosis Life Threatening 7 Female 12/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Life Threatening 7 Female 12/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoxia Hospitalization 12/22/2010 3 Male 39 lb 12/24/2010 United States
Primary
Secondary
Abdominal Pain Hospitalization 3/14/2009 22 Female 128 lb 1/3/2011 Physician United States
Primary
Secondary
Hypoxia Hospitalization 12/27/2010 21 Female 161 lb 12/29/2010 United States
Primary
Secondary
Pupil Fixed Hospitalization 1/18/2011 12 Male 67 lb 1/20/2011 United States
Primary
Secondary
Proteinuria Hospitalization 11/22/2010 13 Female 98 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Fungal Infection Other Serious Male 2/15/2011 Other Health Professional Brazil
Primary
Secondary
Blood Fibrinogen Decreased Hospitalization 1/29/2011 38 Male 207 lb 2/10/2011 Physician United States
Primary
Secondary
Neurotoxicity Hospitalization 5 Female 2/17/2011 Other Health Professional Spain
Primary
Concomitant
Neurotoxicity Hospitalization 5 Female 2/17/2011 Other Health Professional Spain
Primary
Concomitant
Proteinuria Hospitalization 11/22/2010 13 Female 98 lb 2/8/2011 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 5 Female 2/23/2011 Other Health Professional Spain
Primary
Secondary
Hyperglycaemia Hospitalization 10/18/2010 15 Female 128 lb 2/15/2011 Physician United States
Primary
Secondary
Aspartate Aminotransferase Increased 2/7/2011 25 Male 176 lb 2/9/2011 United States
Primary
Secondary
Liver Abscess Other Serious 12 Male 2/28/2011 Other Health Professional Brazil
Primary
Secondary
Hepatic Steatosis Hospitalization 5/28/2010 16 Male 227 lb 2/15/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/22/2010 13 Female 98 lb 2/15/2011 Physician United States
Primary
Secondary
Concomitant
Blood Fibrinogen Decreased Hospitalization 1/29/2011 38 Male 207 lb 2/22/2011 United States
Primary
Secondary
Headache Hospitalization 2/13/2011 22 Male 169 lb 3/8/2011 United States
Primary
Secondary
Thought Blocking Hospitalization 2/16/2011 22 Male 169 lb 3/8/2011
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased 2/7/2011 25 Male 176 lb 3/7/2011 Physician United States
Primary
Secondary
Neurotoxicity Other Serious 1/1/2010 56 Female 128 lb 3/7/2011 Pharmacist Canada
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 8/1/2008 30 Female 176 lb 3/24/2011 Consumer United Kingdom
Primary
Secondary
Hyperglycaemia 12/22/2010 10 Female 65 lb 3/22/2011 United States
Primary
Secondary
Cardiotoxicity Other Serious 17 Female 4/7/2011 Other Health Professional Germany
Primary
Secondary
Subclavian Vein Thrombosis Hospitalization 7 Female 3/31/2011 Physician Germany
Primary
Concomitant
Myelopathy Other Serious 31 Female 7/18/2011 Other Health Professional Switzerland
Primary
Concomitant
Cholestasis Hospitalization 9/1/2010 59 Female 1/23/2012 Other Health Professional France
Primary
Concomitant
Staphylococcal Sepsis Death 22 Female 2/7/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Hallucination, Auditory Hospitalization 2/14/2012 36 Male 4/3/2012 Other Health Professional France
Primary
Concomitant
Hallucination, Auditory Hospitalization 2/14/2012 36 Male 142 lb 5/22/2012 Other Health Professional France
Primary
Concomitant
Coma Hospitalization 2/14/2012 36 Male 142 lb 7/11/2012 Other Health Professional France
Primary
Concomitant
Coma Hospitalization 2/14/2012 36 Male 142 lb 7/23/2012 Other Health Professional France
Primary
Concomitant
Staphylococcal Infection Hospitalization 4/23/2012 4 Female 11/19/2012 Physician Us
Primary
Secondary
Concomitant
Renal Failure Death 74 Male 9/24/2012 Physician Us
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 5 Male 9/14/2012 Other Health Professional Us
Primary
Secondary
Renal Failure Acute Hospitalization 5/31/2012 51 Female 2/22/2013 Other Health Professional Us
Primary
Secondary
Zygomycosis Hospitalization 8/16/2012 Female 32 lb Other Health Professional Us
Primary
Secondary
Sepsis Death 4/6/2012 44 Female 162 lb 10/30/2012 Physician Ca
Primary
Concomitant
Tachycardia Death 8/22/2012 Male 40 lb 9/11/2012 Us
Primary
Secondary
Blood Cholesterol Increased Hospitalization 5/18/2012 Female 206 lb 9/13/2012 Physician Country Not Specified
Primary
Secondary
Sinus Tachycardia Hospitalization 7/31/2012 25 Male 317 lb 12/7/2012 Physician Nl
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/10/2012 11 Male 1/18/2013 Physician Us
Primary
Secondary
Concomitant
Stomatitis Hospitalization 8/10/2012 11 Male 2/4/2013 Physician Us
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Hospitalization 8/6/2012 24 Female 9/26/2012 Consumer Us
Primary
Secondary
Concomitant
Central Nervous System Lesion Other Serious 25 Female 10/15/2012 Physician Nl
Primary
Concomitant
Zygomycosis Death 8/6/2012 Male 172 lb 9/24/2012 Us
Primary
Secondary
Respiratory Failure 6/8/2011 Female 155 lb 9/21/2012 Other Health Professional Us
Primary
Secondary
Skin Infection Hospitalization 2012 10 Female 99 lb 12/20/2012 Consumer Us
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Hospitalization 8/2012 24 Female 9/28/2012 Consumer Us
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/8/2012 Male 194 lb 9/8/2012 Us
Primary
Secondary
Renal Failure Acute Hospitalization 9/21/2012 Male 510 lb Other Health Professional Us
Primary
Secondary
Febrile Neutropenia Hospitalization 9/19/2012 1 Male 18 lb 10/3/2012 Physician Us
Primary
Secondary
Thrombocytopenia Hospitalization 9/27/2012 Female 140 lb 10/3/2012 Other Health Professional Us
Primary
Secondary
Hodgkin's Disease Other Serious 60 Male 1/4/2013 Physician Fr
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/8/2012 Male 194 lb 10/4/2012 Physician Us
Primary
Secondary
Transaminases Increased Other Serious 6/7/2012 20 Male 254 lb 10/9/2012 Consumer Us
Primary
Secondary
Stomatitis Life Threatening 2012 Female 126 lb 10/9/2012 Consumer Us
Primary
Secondary
Urinary Tract Infection Enterococcal Life Threatening 7/27/2012 13 Female 271 lb 11/9/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 12 Female 10/15/2012 Physician Us
Primary
Secondary
Systemic Candida Hospitalization 9/21/2012 Male 510 lb 10/15/2012 Us
Primary
Secondary
Concomitant
Skin Infection Life Threatening 2012 17 Female 100 lb 10/22/2012 Consumer Us
Primary
Secondary
Coagulopathy Life Threatening 10/10/2009 13 Male 99 lb 10/24/2012 Physician Us
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/1/2012 57 Female 231 lb 1/28/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Stomatitis Death 8/5/2011 44 Male 10/11/2012 Us
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2012 51 Female 2/20/2013 Consumer Us
Primary
Secondary
Concomitant
Trendelenburg's Symptom Required Intervention 12 Female 10/18/2012 Other Health Professional Us
Primary
Secondary
Tachycardia Hospitalization 10/17/2012 Male 117 lb 10/25/2012 Country Not Specified
Primary
Secondary
Sepsis Death 11/13/2012 Physician Sg
Primary
Secondary
Off Label Use Life Threatening 9/21/2012 2 Male 23 lb 11/20/2012 Consumer De
Primary
Secondary
Swollen Tongue Hospitalization 10/10/2012 Male 32 lb 10/31/2012 Other Health Professional Us
Primary
Secondary
Skin Necrosis Hospitalization 11/1/2012 Female 37 lb 11/2/2012 Other Health Professional Us
Primary
Secondary
Glucose Tolerance Impaired Hospitalization 11/1/2012 Female 106 lb 11/2/2012 Other Health Professional Us
Primary
Secondary
Pneumothorax Death 11/13/2012 Physician Sg
Primary
Secondary
Zygomycosis Hospitalization 11/1/2012 Physician Us
Primary
Secondary
Vomiting Hospitalization 8/29/2012 10 Male 11/5/2012 Physician Us
Primary
Secondary
Concomitant
Toxic Dilatation Of Intestine Other Serious 6 Male 11/13/2012 Other Health Professional In
Primary
Secondary
Pancreatic Enzymes Increased Other Serious Male 11/8/2012 Physician At
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 10/26/2012 Female 108 lb 11/12/2012 Physician Country Not Specified
Primary
Secondary
Thrombocytopenia Hospitalization 7 Male 11/1/2012 Other Health Professional In
Primary
Secondary
Vomiting Hospitalization 11/14/2012 Female 222 lb 11/15/2012 Country Not Specified
Primary
Secondary
Transaminases Increased Hospitalization 9/14/2012 Female 172 lb 11/9/2012 Physician Country Not Specified
Primary
Secondary
Transaminases Increased Hospitalization 9/14/2012 Female 172 lb 11/8/2012 Physician Us
Primary
Secondary
Mucosal Inflammation Other Serious 8/19/2012 4 Female 11/16/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Pyrexia Other Serious 18 Male 11/29/2012 Other Health Professional Kr
Primary
Secondary
Osteonecrosis Hospitalization 13 Female 12/3/2012 Other Health Professional Country Not Specified
Primary
Secondary
Sepsis Hospitalization 11/22/2012 0 Male 16 lb 12/3/2012 Physician Us
Primary
Secondary
Pneumatosis Intestinalis Other Serious 18 Male 12/5/2012 Other Health Professional Kr
Primary
Secondary
Venoocclusive Liver Disease Death 9 Male 88 lb 12/5/2012 Other Health Professional Jp
Primary
Secondary
Pneumatosis Intestinalis Other Serious 18 Male 12/6/2012 Other Health Professional Kr
Primary
Secondary
Venoocclusive Liver Disease Death 9 Male 88 lb 12/12/2012 Other Health Professional Jp
Primary
Secondary
Venoocclusive Liver Disease Death 9 Male 88 lb 12/20/2012 Other Health Professional Jp
Primary
Secondary
Zygomycosis Hospitalization 32 Male 1/4/2013 Other Health Professional It
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 60 Male 1/2/2013 Other Health Professional Fr
Primary
Concomitant
Venoocclusive Liver Disease Death 6/27/2012 9 Male 12/20/2012 Jp
Primary
Secondary
Thrombocytopenia Other Serious 6 Male 11/1/2012 Other Health Professional In
Primary
Secondary

Drug Data