Methotrexate combined with Trazodone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Prostate Examination Abnormal Hospitalization 10/1/2005 Male 253 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Tongue Disorder Hospitalization 9/28/2005 75 Female 115 lb 11/19/2005 Pharmacist United States
Primary
Concomitant
Ankle Fracture Other Serious 8/1/2005 Female 281 lb 1/24/2006 Physician United States
Primary
Concomitant
Paraesthesia Hospitalization 2/28/2006 Female 268 lb 3/9/2006 Consumer United States
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 1/1/2006 Female 3/17/2006 Physician Canada
Primary
Concomitant
Yellow Skin 1/1/2008 Female 4/5/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 53 Female 145 lb 7/14/2009 United States
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Colon Cancer Other Serious 10/10/2008 Female 130 lb 9/4/2009 Physician United States
Primary
Concomitant
Muscle Spasms 9/13/2006 Female 241 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Haematoma 3/21/2007 Male 231 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/22/2007 Female 361 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Irritation 11/29/2007 Female 399 lb 9/12/2009 Consumer United States
Primary
Concomitant
Sinusitis 12/1/2007 Female 138 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 6/26/2008 Female 185 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Headache Female 160 lb 9/19/2009 United States
Primary
Concomitant
Drug Dose Omission 8/1/2009 Female 9/19/2009 United States
Primary
Concomitant
Suicide Attempt Other Serious 2/2/2001 30 Female 273 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/22/2003 42 Female 246 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/17/2009 77 Female 172 lb 10/2/2009 United States
Primary
Secondary
Concomitant
Urine Odour Abnormal Hospitalization 9/17/2009 77 Female 172 lb 10/13/2009 United States
Primary
Secondary
Concomitant
Umbilical Hernia 1/1/1998 Male 12/4/2009 Physician United States
Primary
Concomitant
Injection Site Pain 1/2/2008 Female 233 lb 12/6/2009 Physician United States
Primary
Concomitant
Productive Cough 2/10/2009 Female 231 lb 12/8/2009 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2007 Female 1/21/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2007 Female 2/5/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Life Threatening 10/23/2009 Female 208 lb 2/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Thrombosis Other Serious 1/27/2010 Male 226 lb 2/8/2010 Canada
Primary
Concomitant
Visual Impairment Other Serious 1/1/2008 Female 2/10/2010 United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2007 Female 2/18/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 4/9/2010 Other Health Professional United States
Primary
Concomitant
Oedema 1/28/2010 54 Female 4/12/2010 Consumer United States
Primary
Concomitant
Fatigue Female 4/12/2010 Consumer United States
Primary
Concomitant
Bone Disorder Other Serious 1/1/2006 61 Female 129 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Tachypnoea Other Serious 8/30/2007 59 Female 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Pelvic Fracture Other Serious 3/8/2010 60 Female 5/12/2010 Consumer United States
Primary
Concomitant
Retching 9/4/2006 43 Female 100 lb 7/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 7/22/2010 United States
Primary
Secondary
Concomitant
Nausea 7/2/2008 59 Female 165 lb 7/22/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 7/26/2010 United States
Primary
Secondary
Concomitant
Small Intestinal Stenosis Hospitalization 7/1/2010 64 Female 164 lb 8/5/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/27/2010 64 Female 164 lb 8/10/2010 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Stenosis Hospitalization 6/27/2010 64 Female 164 lb 8/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Optic Neuritis Disability 8/2/2010 67 Female 180 lb 9/29/2010 Other Health Professional United States
Primary
Concomitant
Throat Tightness Other Serious 51 Female 152 lb 10/22/2010 Consumer United States
Primary
Concomitant
Open Wound Hospitalization 9/1/2010 71 Female 10/25/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2010 53 Male 11/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 11/24/2010 United States
Primary
Secondary
Concomitant
Throat Tightness Other Serious Male 157 lb 11/29/2010 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 11/30/2010 United States
Primary
Concomitant
Wheezing Other Serious 8/29/2007 59 Female 12/2/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria 43 Female 12/8/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 12/13/2010 United States
Primary
Secondary
Concomitant
Pruritus 12/14/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization Female 11/5/2010 Physician United States
Primary
Concomitant
Tremor 10/1/2009 12/14/2010 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization Female 110 lb 11/6/2010 Other Health Professional United States
Primary
Concomitant
Open Wound Hospitalization 9/1/2010 71 Female 112 lb 1/10/2011 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 12/27/2010 68 Female 158 lb 1/13/2011 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin 12/27/2010 68 Female 158 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Headache 2/11/2010 62 Female 140 lb 1/28/2011 United States
Primary
Concomitant
Alopecia Female 140 lb 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Bronchitis 1/1/2009 28 Female 273 lb 1/28/2011 Physician United States
Primary
Concomitant
Alopecia 3/1/2010 54 Female 155 lb 1/28/2011 Consumer United States
Primary
Concomitant
Injection Site Extravasation 4/11/2010 62 Female 140 lb 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pruritus 5/31/2010 28 Female 1/29/2011 Consumer United States
Primary
Concomitant
Pain 7/2/2010 78 Female 1/29/2011 Consumer United States
Primary
Concomitant
Mobility Decreased 1/1/2009 54 Female 209 lb 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 5/11/2010 Male 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Haematoma 5/25/2010 37 Male 1/29/2011 Consumer Zimbabwe
Primary
Concomitant
Drug Dose Omission 7/6/2010 38 Male 1/29/2011 Consumer United States
Primary
Concomitant
Sneezing 10/1/2010 60 Female 125 lb 1/30/2011 Consumer
Primary
Concomitant
Injection Site Pain 11/12/2010 52 Female 1/30/2011 Consumer United States
Primary
Concomitant
Cough 6/1/2010 54 Female 1/30/2011 Consumer United States
Primary
Concomitant
Injection Site Rash 9/26/2010 63 Female 1/30/2011 Consumer United States
Primary
Concomitant
Fibula Fracture Other Serious 6/9/2010 56 Female 1/30/2011 Consumer United States
Primary
Concomitant
Pain 12/8/2010 62 Male 1/30/2011 Consumer United States
Primary
Concomitant
Chest Discomfort 11/13/2010 44 Female 1/30/2011 Consumer United States
Primary
Concomitant
Arthralgia 9/1/2010 43 Female 1/30/2011 Consumer United States
Primary
Concomitant
Foot Fracture Other Serious 11/1/2009 47 Female 218 lb 1/30/2011 Consumer United States
Primary
Concomitant
Limb Operation Other Serious 9/18/2010 61 Male 1/30/2011 Consumer United States
Primary
Concomitant
Cyst Other Serious 12/21/2010 49 Female 121 lb 1/31/2011 Other Health Professional Canada
Primary
Concomitant
Accidental Overdose Other Serious 1/5/2011 36 Male 1/20/2011 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 12/13/2010 75 Female 115 lb 2/9/2011 Physician Canada
Primary
Concomitant
Lymphoma Other Serious 8/1/2010 57 Female 121 lb 2/10/2011 Consumer Brazil
Primary
Concomitant
Impaired Driving Ability Other Serious 3/7/2011 66 Female 180 lb 3/15/2011 Consumer United States
Primary
Concomitant
Headache Other Serious 10/27/2010 56 Female 161 lb 3/17/2011 Other Health Professional Canada
Primary
Concomitant
Visual Impairment Other Serious 3/7/2011 66 Female 180 lb 3/21/2011 Consumer United States
Primary
Concomitant
Oedema Mouth Hospitalization 7/1/2010 52 Female 137 lb 3/25/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/1/2011 34 Male 3/28/2011 Other Health Professional United States
Primary
Concomitant
Postoperative Wound Infection Hospitalization 8/13/2009 51 Female 276 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 3/1/2011 34 Male 4/11/2011 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 6/29/2010 69 Male 4/14/2011 Other Health Professional Canada
Primary
Concomitant
Muscle Spasms Other Serious 1/1/2010 62 Female 140 lb 4/14/2011 Consumer United States
Primary
Secondary
Concomitant
Death Death 3/1/2011 34 Male 4/20/2011 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Other Serious 1/1/2010 28 Female 195 lb 4/20/2011 Consumer United States
Primary
Concomitant
Localised Infection Other Serious 8/27/2010 28 Female 125 lb 4/26/2011 Consumer Canada
Primary
Concomitant
Balance Disorder 1/1/2010 53 Female 5/9/2011 Consumer United States
Primary
Concomitant
Fall Other Serious 1/1/2010 53 Female 5/9/2011 United States
Primary
Concomitant
Chest Pain Hospitalization 4/1/2011 63 Female 156 lb 5/9/2011 Physician United States
Primary
Concomitant
Bladder Disorder 5/1/2011 47 Female 226 lb 6/13/2011 Consumer United States
Primary
Concomitant
Drug Effect Decreased Other Serious 1/1/2009 45 Female 226 lb 6/15/2011 Consumer United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2007 57 Female 117 lb 7/20/2011 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome 4/1/2012 45 Female 300 lb 4/23/2012 Consumer United States
Primary
Concomitant
Erythema Other Serious 4/2/2012 55 Male 203 lb 4/27/2012 Pharmacist Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/26/2010 52 Female 1/9/2013 Consumer Us
Primary
Concomitant
Pain Other Serious 6/9/2010 56 Female 1/7/2013 Consumer Country Not Specified
Primary
Concomitant
Renal Failure Acute Hospitalization 4/4/2011 44 Male 171 lb 3/4/2013 Physician Us
Primary
Secondary
Concomitant
Drug Ineffective 9/12/2011 55 Male 220 lb 10/23/2012 Consumer Us
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/26/2011 69 Male 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Rheumatoid Arthritis 1/30/2011 59 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Rheumatoid Arthritis Disability 10/2011 50 Female 3/21/2013 Other Health Professional Co
Primary
Concomitant
Sepsis Disability 11/14/2011 66 Female 364 lb 10/23/2012 Consumer Us
Primary
Concomitant
Vomiting Other Serious 2/2012 41 Female 11/6/2012 Other Health Professional Co
Primary
Secondary
Concomitant
Pruritus Other Serious 2011 Female 214 lb 12/18/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Psoriatic Arthropathy Other Serious 2010 55 Male 10/10/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Thyroid Neoplasm Other Serious 53 Female 10/17/2012 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pain Female 173 lb 10/23/2012 Physician Us
Primary
Concomitant
Injection Site Bruising 58 Female 185 lb 10/24/2012 Physician Us
Primary
Concomitant
Sinusitis 57 Female 10/24/2012 Physician Us
Primary
Concomitant
Papule 58 Female 120 lb 10/25/2012 Other Health Professional Us
Primary
Concomitant
Weight Increased 2/29/2012 52 Female 10/25/2012 Physician Us
Primary
Concomitant
Weight Increased 6/7/2012 66 Female 198 lb 10/26/2012 Consumer Us
Primary
Concomitant
Influenza Like Illness 2/7/2012 43 Female 134 lb 10/26/2012 Physician Us
Primary
Concomitant
Drug Ineffective Female 115 lb 10/26/2012 Physician Us
Primary
Concomitant
Drug Ineffective 2012 Female 154 lb 10/26/2012 Consumer Us
Primary
Concomitant
Stomatitis 9/7/2009 47 Female 225 lb 10/23/2012 Physician Us
Primary
Concomitant
Injection Site Erythema 4/12/2004 52 Female 140 lb 10/25/2012 Other Health Professional Us
Primary
Concomitant
Fatigue 6/8/2011 37 Female 11/7/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Nasopharyngitis 11/6/2011 81 Male 331 lb 11/7/2012 Physician Us
Primary
Concomitant
Upper Respiratory Tract Infection 11/6/2009 63 Male 310 lb 11/7/2012 Other Health Professional Us
Primary
Concomitant
Candidiasis 7/1/2011 49 Female 11/7/2012 Other Health Professional Us
Primary
Concomitant
Tongue Neoplasm Other Serious 7/2012 54 Female 3/3/2013 Other Health Professional Ca
Primary
Concomitant
Sinusitis 3/2012 Male 155 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Injection Site Swelling Male 192 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Pyrexia 41 Female 11/8/2012 Physician Us
Primary
Concomitant
Pain Female 130 lb 11/8/2012 Physician Us
Primary
Concomitant
Drug Ineffective 4/23/2012 38 Female 250 lb 11/8/2012 Physician Us
Primary
Concomitant
Euphoric Mood 28 Male 11/8/2012 Physician Us
Primary
Concomitant
Skin Infection Other Serious 4/2012 72 Female 163 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Eye Infection 2/18/2012 51 Female 11/13/2012 Physician Us
Primary
Concomitant
Influenza Like Illness 1/2012 68 Female 161 lb 11/13/2012 Physician Us
Primary
Concomitant
Fatigue 2/2/2012 50 Female 198 lb 11/13/2012 Other Health Professional Us
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 10/17/2012 Female 200 lb 8/10/2013 Consumer Us
Primary
Concomitant
Coeliac Disease Other Serious 6/2012 Female 209 lb 11/28/2012 Other Health Professional Ca
Primary
Concomitant
Vomiting Other Serious 2012 41 Female 12/5/2012 Consumer Co
Primary
Secondary
Concomitant
Mineral Supplementation Other Serious 10/2012 Female 252 lb 1/11/2013 Other Health Professional Ca
Primary
Concomitant
Post Procedural Infection 3/22/2012 60 Female 141 lb 10/29/2012 Physician Us
Primary
Concomitant
Vocal Cord Paralysis Hospitalization Female 11/9/2012 Physician Us
Primary
Concomitant

Drug Data