Diltiazem combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Swelling Other Serious 1/1/2006 56 Female 287 lb 3/27/2006 Physician Switzerland
Primary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 119 lb 4/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 119 lb 4/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/30/2006 Male 119 lb 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Hospitalization 10/1/2005 Female 5/25/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 115 lb 6/2/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 115 lb 6/2/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 6/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Bradycardia Hospitalization 6/12/2006 65 Male Pharmacist United States
Primary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 8/3/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious Female 194 lb 11/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 2/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 3/20/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/15/2007 Male 205 lb 4/19/2007 Consumer Canada
Primary
Concomitant
Rash Maculo-papular Hospitalization 9/13/2007 65 Female 10/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Mycobacterium Abscessus Infection Other Serious Female 172 lb 10/11/2007 Other Health Professional United States
Primary
Concomitant
Bronchospasm Other Serious 9/4/2007 Female 10/12/2007 Physician
Primary
Concomitant
Meningitis Aseptic Hospitalization 62 Male 10/25/2007
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2007 Female 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2007 Female 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Eosinophilia Other Serious 3/4/1999 53 Female 11/27/2007 France
Primary
Concomitant
Tenosynovitis Other Serious 62 Male 11/28/2007 Pharmacist Canada
Primary
Concomitant
Nasopharyngitis 3/24/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Injection Site Swelling 7/1/2007 Female 160 lb 12/14/2007 Consumer United States
Primary
Concomitant
Kidney Infection 8/1/2007 Female 167 lb 12/14/2007 Physician United States
Primary
Concomitant
Drug Ineffective 1/1/2005 Female 223 lb 12/14/2007 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 12/1/2007 Female 2/6/2008 Physician United States
Primary
Concomitant
Pelvic Fracture Hospitalization 2/5/2007 Female 130 lb 2/18/2008 Canada
Primary
Concomitant
Pelvic Fracture Hospitalization 2/5/2007 Female 130 lb 3/3/2008 Canada
Primary
Concomitant
Multiple Drug Overdose Hospitalization 36 Female 2/28/2008 Physician United States
Primary
Secondary
Concomitant
Accidental Needle Stick Female 3/15/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 3/12/2008 Female 145 lb 6/13/2008 Consumer United States
Primary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 7/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 10/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Injection Site Pain 8/27/2008 Male 175 lb 12/12/2008 Consumer United States
Primary
Concomitant
Oral Pain 7/1/2008 Male 340 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Localised Infection 9/4/2008 Female 160 lb 12/12/2008 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2008 Female 12/12/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Reaction 4/23/2008 Female 142 lb 12/15/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/15/2008 Female 154 lb 12/22/2008 Consumer Argentina
Primary
Concomitant
Urinary Tract Infection Other Serious 9/13/2008 Female 164 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Skin Ulcer Hospitalization 5/1/2007 Female 1/26/2009 Physician Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 5/9/2008 Male 170 lb 2/25/2009 United Kingdom
Primary
Concomitant
Ulcer Hospitalization 12/21/2008 Male 170 lb 2/26/2009 United Kingdom
Primary
Concomitant
Gastric Ulcer Hospitalization 12/21/2008 Male 170 lb 3/20/2009 United Kingdom
Primary
Concomitant
Urine Abnormality Hospitalization 3/2/2009 Female 212 lb 3/27/2009 Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/4/2009 58 Female 4/16/2009 Consumer Brazil
Primary
Concomitant
Urine Abnormality Hospitalization 3/2/2009 Female 212 lb 4/30/2009 Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/4/2009 58 Female 4/30/2009 Other Health Professional Brazil
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 Male 274 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Nodule Removal Other Serious 1/1/2007 Female 180 lb 6/25/2009 Canada
Primary
Concomitant
Rheumatoid Nodule Other Serious 1/1/2007 Female 180 lb 6/30/2009 Canada
Primary
Concomitant
Rheumatoid Nodule Other Serious 1/1/2007 Female 180 lb 7/9/2009 Canada
Primary
Concomitant
Cardiac Disorder Hospitalization 2/1/2009 Female 7/16/2009 United States
Primary
Concomitant
Oral Pain Hospitalization 6/1/2009 Female 160 lb 7/27/2009 Canada
Primary
Concomitant
Sepsis Pasteurella Other Serious 6/1/2008 Male 184 lb 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/6/2009 Female 196 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 Male 274 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 6/15/2008 Female 8/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 5/9/2008 Male 170 lb 8/21/2009 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/1/2009 83 Female 103 lb 9/5/2009 Pharmacist United States
Primary
Concomitant
Incorrect Dose Administered 10/10/2006 Female 155 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Haematoma 3/21/2007 Male 231 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation Female 9/12/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/27/2008 Male 175 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/17/2008 Male 196 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/14/2008 Male 205 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting Death 3/2/2008 69 Female 9/8/2009 United States
Primary
Concomitant
Wheezing Other Serious 2/24/2009 Female 9/30/2009 Other Health Professional Canada
Primary
Concomitant
Lower Limb Fracture Other Serious 11/6/2008 Female 10/8/2009 Physician Canada
Primary
Concomitant
Vomiting Death 3/2/2008 78 Female 10/17/2009 United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 9/9/2009 Female 122 lb 11/9/2009 United States
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 10/29/2009 Male 139 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 9/9/2009 Female 122 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Sepsis Death 6/15/2008 Female 12/9/2009 Consumer United Kingdom
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 10/29/2009 Male 139 lb 12/23/2009 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2004 Female 1/8/2010 Physician United States
Primary
Concomitant
Insomnia 49 Female 1/24/2010 Consumer United States
Primary
Concomitant
Rash 9/7/2009 Female 142 lb 1/29/2010 United States
Primary
Concomitant
Injection Site Reaction Female 230 lb 1/29/2010 United States
Primary
Concomitant
Palpitations 7/1/2009 Female 140 lb 1/30/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/23/2007 62 Female 196 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/15/2010 67 Male 161 lb 4/30/2010 Other Health Professional France
Primary
Concomitant
Tremor Hospitalization 5/1/2010 56 Male 132 lb 5/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Disorder Other Serious 57 Female 6/1/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2010 76 Female 6/23/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2009 74 Female 6/30/2010 Consumer United States
Primary
Concomitant
Nausea 6/1/2007 62 Male 190 lb 7/13/2010 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 6/24/2010 73 Female 170 lb 7/14/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 69 Female 205 lb 7/30/2010 Consumer Brazil
Primary
Concomitant
Headache Other Serious 1/1/2008 65 Female 134 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Listeriosis Life Threatening 62 Female 8/16/2010 Physician United States
Primary
Concomitant
Heart Valve Incompetence Other Serious 7/31/2010 64 Female 8/19/2010 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 63 Male 274 lb 8/23/2010 Physician United States
Primary
Concomitant
Heart Valve Incompetence Other Serious 7/31/2010 64 Female 8/24/2010 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 63 Male 274 lb 9/2/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/26/2010 77 Male 9/10/2010 Physician Australia
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 76 Female 150 lb 9/20/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 12/12/2009 76 Female 150 lb 9/20/2010 Consumer United States
Primary
Concomitant
Surgery Other Serious 11/6/2008 69 Female 10/1/2010 Canada
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/26/2010 77 Male 130 lb 10/11/2010 Physician Australia
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 9/1/2010 46 Female 180 lb 10/13/2010 Physician Canada
Primary
Concomitant
Pregnancy Other Serious 10/14/2010 34 Female 119 lb 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 3/1/2010 60 Female 141 lb 11/17/2010 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/26/2010 77 Male 130 lb 11/23/2010 Physician Australia
Primary
Secondary
Concomitant
Sepsis Other Serious 12/16/2004 87 Male 157 lb 11/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Underdose Other Serious 3/1/2010 60 Female 141 lb 12/28/2010 Physician United Kingdom
Primary
Concomitant
Erythema Other Serious 7/1/2010 52 Female 137 lb 1/6/2011 Consumer United States
Primary
Concomitant
Anorectal Disorder Other Serious 11/1/2010 62 Female 179 lb 1/14/2011 Physician France
Primary
Concomitant
Diarrhoea Hospitalization 1/1/2009 1/17/2011 Consumer United States
Primary
Concomitant
Anal Cancer Other Serious 11/1/2010 62 Female 179 lb 1/28/2011 Physician France
Primary
Concomitant
Contusion 6/1/2010 62 Female 1/29/2011 Consumer United States
Primary
Concomitant
Hypothyroidism 1/1/2009 66 Male 190 lb 1/29/2011 Physician
Primary
Concomitant
Vertigo 7/18/2010 73 Female 1/29/2011 Consumer United States
Primary
Concomitant
Diverticulitis Other Serious 11/21/2010 63 Female 185 lb 1/30/2011 Consumer United States
Primary
Concomitant
Nasopharyngitis Female 1/30/2011 Consumer United States
Primary
Concomitant
Bursitis Hospitalization 7/23/2010 74 Male 1/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Abortion Spontaneous Other Serious 10/14/2010 34 Female 119 lb 3/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Vesicular 12/15/2010 83 Female 3/8/2011 Other Health Professional United States
Primary
Concomitant
Malaise Other Serious 2/26/2011 78 Female 102 lb 3/21/2011 Consumer Canada
Primary
Concomitant
No Reaction On Previous Exposure To Drug 3/3/2011 69 Female 159 lb 3/7/2011 Pharmacist United States
Primary
Concomitant
Drug Ineffective Other Serious 2/27/2011 75 Female 4/13/2011 Consumer United States
Primary
Concomitant
Palpitations Other Serious 2/27/2011 75 Female 154 lb 5/4/2011 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization Male 5/6/2011 United States
Primary
Concomitant
Muscle Spasms Other Serious Male 203 lb 5/6/2011 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 3/7/2009 62 Male 274 lb 5/6/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 2/27/2011 75 Female 154 lb 5/9/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 2/1/2011 68 Male 5/12/2011 Consumer United States
Primary
Concomitant
Embolism Venous Other Serious 11/1/2010 64 Female 5/26/2011 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 3/1/2010 60 Female 142 lb 5/31/2011 Consumer United Kingdom
Primary
Concomitant
Blood Creatinine Increased Other Serious 4/19/2011 69 Female 128 lb 6/7/2011 Physician United States
Primary
Concomitant
Inguinal Hernia Other Serious Male 163 lb 6/20/2011 Other Health Professional Canada
Primary
Concomitant
Febrile Neutropenia Life Threatening 7/18/2010 61 Female 110 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 4/10/2011 54 Female 159 lb 6/27/2011 Other Health Professional Canada
Primary
Concomitant
Pain Other Serious 6/16/2011 76 Female 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Malaise Other Serious 2/26/2011 78 Female 104 lb 7/6/2011 Other Health Professional Canada
Primary
Concomitant
Diarrhoea Hospitalization 4/19/2011 69 Female 128 lb 7/18/2011 Physician United States
Primary
Concomitant
Alopecia Other Serious 11/1/2010 64 Female 199 lb 7/23/2011 Physician United States
Primary
Concomitant
Grip Strength Decreased Hospitalization 6/1/2011 63 Female 8/9/2011 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Other Serious 6/1/2004 78 Female 8/24/2011 Consumer Finland
Primary
Concomitant
Vomiting Other Serious 9/1/2011 63 Male 162 lb 9/12/2011 Other Health Professional Canada
Primary
Concomitant
Dental Caries Other Serious 7/1/2004 63 Female 9/9/2011 Physician United States
Primary
Concomitant
Joint Stiffness Hospitalization 6/1/2011 63 Female 9/16/2011 Consumer United States
Primary
Concomitant
Mobility Decreased Hospitalization 7/1/2004 63 Female 9/19/2011 Physician United States
Primary
Concomitant
Parathyroid Disorder Other Serious 1/1/2011 68 Female 11/23/2011 Consumer United States
Primary
Concomitant
Parathyroid Disorder Other Serious 1/1/2011 68 Female 12/21/2011 Physician United States
Primary
Concomitant
Medication Error Death 1/1/2010 73 Female 12/30/2011 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2010 73 Female 1/3/2012 Other Health Professional United States
Primary
Secondary
Viral Infection Hospitalization 4/6/2011 75 Female 1/5/2012 Other Health Professional
Primary
Secondary
Concomitant
Nausea Hospitalization 4/6/2011 75 Female 1/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data