Methotrexate combined with Vfend

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transplant Failure Hospitalization 11/21/2005 Male 176 lb 2/1/2006 Physician Germany
Primary
Concomitant
Tachycardia Hospitalization 2/7/2006 28 Male 123 lb 3/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/25/2006 28 Male 123 lb 3/24/2006 France
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 3/1/2006 61 Male 196 lb 8/8/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/25/2006 42 Male 165 lb 10/24/2006 Physician Japan
Primary
Concomitant
Skin Depigmentation Other Serious 7/25/2006 12 Female 75 lb 10/31/2006 Physician United Kingdom
Primary
Concomitant
Pneumonia Death 9/13/2005 36 Male 176 lb 1/30/2007 Physician Japan
Primary
Secondary
Concomitant
Polyserositis Other Serious 10/15/2006 Female 104 lb 4/6/2007 Physician Switzerland
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/15/2006 15 Female 104 lb 4/16/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 5/21/2007 17 Male 7/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 4/1/2007 17 Male 7/25/2007 Consumer France
Primary
Secondary
Concomitant
Cerebellar Syndrome Hospitalization 5/21/2007 Male 8/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Cerebellar Syndrome Hospitalization 5/21/2007 17 Male 8/2/2007
Primary
Secondary
Ventricular Fibrillation Hospitalization 4/30/2007 Male 8/6/2007 Other Health Professional France
Primary
Secondary
Ventricular Fibrillation Hospitalization 4/30/2007 Male 8/13/2007 Other Health Professional France
Primary
Secondary
Ventricular Fibrillation Hospitalization 5/1/2007 17 Male 8/14/2007 France
Primary
Secondary
Ventricular Fibrillation Hospitalization 5/21/2007 17 Male 8/22/2007
Primary
Secondary
Ventricular Fibrillation Life Threatening 4/30/2007 Male 8/30/2007 Other Health Professional France
Primary
Secondary
Interstitial Lung Disease Hospitalization 6/17/2007 60 Female 110 lb 8/31/2007 Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 12/5/2006 70 Female 9/3/2007 Pharmacist Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 6/17/2007 60 Female 110 lb 9/4/2007 Japan
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 8/28/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 5/1/2007 17 Male 9/10/2007 United States
Primary
Secondary
Leukoencephalopathy Other Serious Female 124 lb 10/15/2007 Physician Japan
Primary
Secondary
Rash Other Serious 9/24/2007 Female 112 lb 11/9/2007 Physician Japan
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 44 Female 12/14/2007 Other Health Professional France
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/17/2007 60 Female 110 lb 1/30/2008 Japan
Primary
Concomitant
Protein Total Decreased Other Serious Male 176 lb 4/21/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Serositis Hospitalization 12/15/2007 Female 104 lb 5/2/2008 United States
Primary
Secondary
Concomitant
Serositis Hospitalization 12/15/2007 Female 104 lb 5/9/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/21/2007 25 Male 112 lb 6/4/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/21/2007 25 Male 112 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 7/28/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Transfusion Death 8/3/2007 9/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/3/2007 24 Male 126 lb 10/20/2008 Consumer Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Shock Haemorrhagic Life Threatening 5/25/2008 1 NotSpecified 22 lb 10/30/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Rash Morbilliform Hospitalization 9/20/2008 Female 31 lb 11/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 1 Male 22 lb 11/12/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 1 Male 22 lb 11/17/2008 Physician Japan
Primary
Concomitant
Rash Morbilliform Hospitalization 9/20/2008 Female 31 lb 12/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/25/2008 62 Female 163 lb 1/23/2009 Consumer France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/25/2008 62 Female 163 lb 1/27/2009 Consumer France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/25/2008 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/1/2008 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 12/22/2008 2/6/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/25/2008 62 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Concomitant
Splenic Abscess Other Serious 11/16/2008 39 Female 126 lb 4/15/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 10/20/2008 Male 154 lb 5/14/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2008 6 Male 60 lb 5/18/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 12/19/2008 59 Male 123 lb 5/28/2009 Japan
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 5/15/2009 27 6/9/2009 Pharmacist Switzerland
Primary
Concomitant
Vomiting Other Serious 3/1/2008 6 Male 60 lb 6/5/2009 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 10/20/2008 Male 154 lb 6/29/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2008 6 Male 60 lb 7/31/2009 Physician Japan
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 46 Male 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/30/2009 15 Male 12/8/2009 Other Health Professional Japan
Primary
Concomitant
Transfusion Death 8/3/2007 2/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/3/2007 Male 126 lb 2/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 6/30/2009 15 Male 2/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/30/2009 15 Male 2/18/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/30/2009 15 Male 88 lb 4/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/30/2009 15 Male 88 lb 4/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
T-cell Lymphoma Hospitalization 11/30/2008 70 Male 4/13/2010 Physician United States
Primary
Secondary
Concomitant
T-cell Lymphoma Hospitalization 11/30/2008 70 Male 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/24/2009 15 Male 88 lb 5/3/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 11/1/2009 74 Male 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Disorder 12/1/2008 3 Female 27 lb 8/6/2010 Consumer United States
Primary
Concomitant
Vision Blurred 1/1/2009 Female 8/6/2010 Physician United States
Primary
Concomitant
Bone Marrow Failure Other Serious 2 Female 9/27/2010 Other Health Professional France
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 2/4/2010 63 Male 128 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 8/30/2010 13 Female 97 lb 10/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 10/8/2009 12 Male 92 lb 11/11/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 10/10/2009 12 Male 92 lb 12/6/2010 Physician Japan
Primary
Concomitant
Oedema Other Serious 8/16/2009 7 Male 66 lb 12/10/2010 Physician Hungary
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 4/23/2009 7 Female 40 lb 12/13/2010 Physician Hungary
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 4/23/2009 7 Female 40 lb 12/30/2010 Physician Hungary
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/13/2010 58 Male 121 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Glossitis Hospitalization 9/13/2010 58 Male 121 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 4/22/2007 41 Male 132 lb 2/4/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Death 7/18/2010 29 Female 82 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 4/30/2007 17 Male 3/1/2011 Other Health Professional France
Primary
Secondary
Systemic Mycosis Hospitalization 4/22/2007 41 Male 132 lb 3/2/2011 Physician Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Death 4/30/2007 17 Male 3/4/2011 Other Health Professional France
Primary
Secondary
Renal Failure Acute Death 2/14/2011 62 Female 110 lb 4/8/2011 Physician Japan
Primary
Concomitant
Sepsis Death 8/19/2009 55 Female 121 lb 4/13/2011 Physician Japan
Primary
Concomitant
Blood Bilirubin Increased Death 6/2/2007 47 Male 119 lb 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Life Threatening 12/7/2009 1 Female 22 lb 4/19/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Life Threatening 12/7/2009 1 Female 22 lb 4/19/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Death 7/17/2010 29 Female 82 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Influenza Life Threatening 2/14/2011 62 Female 110 lb 4/22/2011 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 9/13/2010 58 Male 121 lb 4/25/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 8/19/2009 55 Female 121 lb 5/2/2011 Physician Japan
Primary
Concomitant
Anaphylactic Reaction Hospitalization 4/3/2010 16 Female 95 lb 5/4/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Creatine Increased Death 5/29/2007 47 Male 119 lb 5/5/2011 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 4/22/2007 41 Male 132 lb 5/6/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Infection Life Threatening 11/29/2008 8 Male 46 lb 6/2/2011 Physician Japan
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 3/16/2010 58 Female 106 lb 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/16/2010 58 Female 106 lb 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/1/2011 61 Female 95 lb 7/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bacterial Infection Life Threatening 11/8/2009 15 Male 157 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pericardial Effusion Life Threatening 10/10/2009 12 Male 92 lb 7/5/2011 Physician Japan
Primary
Concomitant
Pneumonia Fungal Death 5/29/2007 47 Male 119 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 7/26/2010 58 Male 6/27/2011 Other Health Professional Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 1/1/2011 61 Female 95 lb 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 1/11/2011 66 Male 8/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Disability 6/6/2011 13 Female 88 lb 9/20/2011 Physician Japan
Primary
Concomitant
Eccentric Fixation Hospitalization 6/21/2011 17 Male 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 1/1/2007 59 Male 10/12/2011 Physician Sweden
Primary
Concomitant
Sepsis Hospitalization 6/9/2011 61 Female 95 lb 10/14/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 1/11/2011 66 Male 11/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 6/21/2011 17 Male 11/8/2011 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Death 6/6/2011 13 Female 88 lb 11/8/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Increased Death 7/23/2010 58 Male 143 lb 11/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Death 7/23/2010 58 Male 143 lb 11/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 6/8/2011 61 Female 101 lb 12/5/2011 Physician Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 6/21/2011 17 Male 12/7/2011 Physician Japan
Primary
Secondary
Concomitant
Dyslalia Other Serious 6/21/2011 17 Male 12/27/2011 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 7/26/2010 58 Male 1/4/2012 Other Health Professional Japan
Primary
Concomitant
Nervous System Disorder Death 4/21/2011 16 Male 95 lb 2/17/2012 Physician Japan
Primary
Secondary
Concomitant
Nervous System Disorder Death 4/21/2011 16 Male 95 lb 3/15/2012 Physician Japan
Primary
Secondary
Concomitant
Hallucination, Auditory Hospitalization 2/14/2012 36 Male 4/3/2012 Other Health Professional France
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 2/13/2012 36 Male 4/3/2012 Other Health Professional France
Primary
Secondary
Concomitant
Dermatitis Exfoliative Hospitalization 2/13/2012 36 Male 4/10/2012 Other Health Professional France
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 6/22/2011 20 Male 203 lb 4/11/2012 Physician Japan
Primary
Secondary
Concomitant
Myelitis Hospitalization 6/22/2011 20 Male 203 lb 4/11/2012 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease In Intestine Other Serious 6/22/2011 20 Male 203 lb 5/16/2012 Physician Japan
Primary
Secondary
Concomitant
Hallucination, Auditory Hospitalization 2/14/2012 36 Male 142 lb 5/22/2012 Other Health Professional France
Primary
Concomitant
Toxic Optic Neuropathy Disability 11/1/2011 21 Male 182 lb 5/24/2012 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Optic Neuropathy Disability 11/1/2011 21 Male 5/25/2012 Physician France
Primary
Secondary
Concomitant
Toxic Optic Neuropathy Disability 11/1/2011 21 Male 182 lb 5/30/2012 Other Health Professional France
Primary
Secondary
Concomitant
Coma Hospitalization 2/14/2012 36 Male 142 lb 7/11/2012 Other Health Professional France
Primary
Concomitant
Candidiasis Hospitalization 5/1/2012 63 Female 7/13/2012 Other Health Professional France
Primary
Secondary
Concomitant
Coma Hospitalization 2/14/2012 36 Male 142 lb 7/23/2012 Other Health Professional France
Primary
Concomitant
Aplasia Other Serious 6/4/2012 64 Female 7/27/2012 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Death 11/18/2009 74 Male 6/26/2013 Consumer Jp
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/11/2011 Male 9/4/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/27/2011 58 Male 126 lb 6/27/2013 Consumer Jp
Primary
Secondary
Concomitant
Nausea Other Serious 11/4/2011 68 Male 6/11/2013 Consumer Jp
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/26/2009 49 Male 4/24/2013 Consumer Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 10/20/2008 Male 154 lb 1/29/2013 Physician Jp
Primary
Secondary
Concomitant
Fluoride Increased Hospitalization 1/12/2013 8 Male 2/20/2013 Other Health Professional Fr
Primary
Concomitant
Atrial Flutter Hospitalization 6/20/2012 60 Male 5/1/2013 Other Health Professional Jp
Primary
Concomitant

Drug Data