Cytoxan combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tongue Disorder Other Serious 12/5/2005 Male 216 lb 12/27/2005 United States
Primary
Secondary
Visual Disturbance Hospitalization 1/1/1999 37 Female 148 lb 2/28/2006 Physician United States
Primary
Concomitant
Neurotoxicity Other Serious 26 Female 3/4/2006 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 19 Male 3/4/2006 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 17 Female 3/4/2006 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 38 Female 3/4/2006 Physician United States
Primary
Concomitant
Abdominal Pain Upper 52 Female 1/25/2006 United States
Primary
Concomitant
Eye Movement Disorder 1/1/2006 47 Female 4/28/2006 Consumer United States
Primary
Concomitant
Vith Nerve Paralysis Hospitalization 69 Female 5/5/2006 Physician United States
Primary
Concomitant
Abdominal Pain 1/19/2006 38 Female 3/1/2006 Consumer United States
Primary
Concomitant
Swelling Other Serious 12/1/2004 64 Female 143 lb 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Vith Nerve Paralysis Hospitalization 69 Female 5/19/2006 Physician United States
Primary
Concomitant
Pyrexia Other Serious 11/1/2003 Female 197 lb 6/22/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 2/21/2006 78 Female 6/26/2006 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 12/1/2004 23 Female 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 11/1/2003 Female 197 lb 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/24/2005 85 Female 7/26/2006 Physician United States
Primary
Concomitant
Pain In Jaw Other Serious 2/21/2006 78 Female 8/4/2006 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2006 Female 8/8/2006 Physician United States
Primary
Secondary
Tooth Extraction Other Serious 2/24/2005 85 Female 8/14/2006 Physician United States
Primary
Concomitant
Weight Increased Life Threatening 8/9/2006 4 Male 43 lb 8/11/2006 Physician United States
Primary
Concomitant
Vith Nerve Paralysis Hospitalization 69 Female 8/23/2006 Physician United States
Primary
Concomitant
Vision Blurred Male 9/14/2006 Other Health Professional United States
Primary
Secondary
Cataract Other Serious 51 Male 269 lb 11/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/26/2003 61 Male 168 lb 11/6/2006 Physician United States
Primary
Secondary
Incorrect Dose Administered Other Serious 51 Male 270 lb 11/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 1/1/2006 Female 3/28/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Chest Pain 2/2/2006 Female 3/28/2007 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 2/26/2007 15 Female 154 lb 4/23/2007 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 2/12/2007 55 Female 170 lb 5/21/2007 Consumer United States
Primary
Secondary
Serum Ferritin Increased Other Serious 12/12/2005 50 Female 141 lb 5/23/2007 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/15/2007 59 Male 234 lb 5/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious Male 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Required Intervention 22 Male 6/8/2007 Physician United States
Primary
Secondary
Weight Decreased Other Serious 7/1/2006 60 Female 158 lb 7/13/2007 Consumer United States
Primary
Secondary
Concomitant
Retinal Vein Thrombosis Hospitalization 4/21/2007 8 8/15/2007 Physician United States
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Retinal Vein Thrombosis Hospitalization 4/21/2007 8 Male 9/19/2007 Physician United States
Primary
Concomitant
Rash 4/24/2007 59 Female 11/13/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 57 Male 1/11/2008 Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2006 60 Female 159 lb 1/30/2008 United States
Primary
Secondary
Concomitant
Speech Rehabilitation Other Serious 1 Female 2/25/2008 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Required Intervention 1/4/2006 44 Female 1/17/2008 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 12/12/2000 42 Female 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 59 Female 5/28/2008 Other Health Professional United States
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Gingival Bleeding 10/1/2007 Female 132 lb 6/23/2008 Physician United States
Primary
Concomitant
Lymphoma Life Threatening 6/17/2008 Male 185 lb 7/7/2008 Physician United States
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 7/17/2008 United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Life Threatening 5/24/2008 Male 185 lb 8/11/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 43 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Death 44 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/2/2008 64 Female 10/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 3/4/2009 23 Male 116 lb 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/12/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 5/20/2009 Pharmacist United States
Primary
Concomitant
Eye Pruritus Life Threatening 4/21/2009 27 Male 166 lb 5/21/2009 Physician United States
Primary
Concomitant
Breast Cancer Death Female 7/1/2009 Physician United States
Primary
Concomitant
Neutropenia Other Serious Male 8/24/2009 Other Health Professional United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 7/3/2008 Female 10/8/2009 Physician United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 10/30/2009 Pharmacist United States
Primary
Concomitant
Axonal Neuropathy Other Serious 9/13/2009 Male 11/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/4/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 1/15/2010 Other Health Professional United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/1/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/5/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/11/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 9/11/2009 56 Female 2/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/26/2010 Pharmacist United States
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/26/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/14/2005 Female 127 lb 3/12/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 3/17/2010 Pharmacist United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 Male 3/18/2010 Physician United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 Male 3/24/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/27/2004 Female 3/26/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 4/8/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 4/12/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 4/14/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 4/20/2010 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 5/7/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 5/7/2010 United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 5/1/2000 48 Female 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/19/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/21/2010 United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 48 Female 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 5/27/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/28/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 6/2/2010 Pharmacist United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2005 60 Female 245 lb 6/2/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 6/9/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 6/11/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2005 60 Female 245 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/27/2004 46 Female 7/8/2010 Physician United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 7/16/2010 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/1999 48 Female 7/16/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 7/30/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 8/6/2010 Physician United States
Primary
Concomitant
Skin Disorder 12/1/2008 3 Female 27 lb 8/6/2010 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 8/1/1999 74 Female 8/11/2010 Lawyer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2005 60 Female 245 lb 8/16/2010 United States
Primary
Secondary
Concomitant
Prostate Cancer Male 8/18/2010 Consumer United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/20/2010 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 8/1/1999 74 Female 8/20/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2005 60 Female 245 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/27/2010 United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/26/2010 Female 8/30/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2005 60 Female 245 lb 9/7/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 6/1/1995 49 Female 245 lb 9/8/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 9/6/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 9/13/2010 Pharmacist United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/26/2006 8 Male 9/17/2010 Physician United States
Primary
Concomitant
Toothache Hospitalization 3/23/2008 19 Female 143 lb 9/28/2010 Consumer
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 7/3/2008 43 Female 9/28/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2005 60 Female 245 lb 10/11/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 10/15/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 10/20/2010 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 6/16/2010 61 Male 10/21/2010 Physician Germany
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2005 60 Female 245 lb 10/26/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 10/27/2010 United States
Primary
Secondary
Concomitant

Drug Data