Cyanocobalamin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rheumatoid Arthritis Other Serious 12/25/2003 56 Female 101 lb 1/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Uterine Disorder Hospitalization 7/1/2000 44 Female 148 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Pseudomonas Infection Other Serious 8/4/2005 Female 97 lb 2/17/2006 Physician Japan
Primary
Secondary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 3/7/2006 Consumer Canada
Primary
Concomitant
Injection Site Cellulitis Other Serious 2/25/2006 Male 311 lb 3/16/2006 Physician Canada
Primary
Concomitant
Tracheal Injury Life Threatening 1/29/2004 70 Male 144 lb 3/27/2006 Physician Japan
Primary
Secondary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 3/27/2006 Physician Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 Male 4/20/2006 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 6/27/2006 Physician Japan
Primary
Concomitant
Tracheal Haemorrhage Life Threatening 1/29/2004 70 Male 144 lb 6/30/2006 Physician Japan
Primary
Concomitant
Hip Arthroplasty Hospitalization Female 150 lb 7/7/2006 Consumer Canada
Primary
Concomitant
Tuberculosis Death 10/18/2002 Female 7/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 7/14/2006 Physician Japan
Primary
Secondary
Concomitant
Lacrimation Increased Other Serious 7/5/2006 Female 120 lb 7/17/2006 Consumer Canada
Primary
Concomitant
Hip Arthroplasty Hospitalization 6/16/2006 Female 150 lb 8/2/2006 Consumer Canada
Primary
Concomitant
Joint Destruction Hospitalization 2/1/2006 Female 150 lb 8/14/2006 Consumer Canada
Primary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 8/21/2006 Physician Canada
Primary
Concomitant
Salivary Gland Mass Other Serious 1/1/2006 Female 240 lb 8/25/2006 Consumer United States
Primary
Concomitant
Heart Valve Replacement Hospitalization 7/13/2006 Male 9/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Facial Palsy Other Serious 7/5/2006 Female 120 lb 9/22/2006 Physician Canada
Primary
Concomitant
Arthropathy Other Serious Female 149 lb 10/9/2006 Consumer Canada
Primary
Concomitant
Unevaluable Event Hospitalization 11/21/2005 32 Female 11/17/2006 Other Health Professional Sweden
Primary
Concomitant
Pain Other Serious 12/27/2006 Female 150 lb 1/5/2007 Consumer Canada
Primary
Concomitant
Pain Hospitalization 9/4/2006 Female 209 lb 1/8/2007 Consumer Canada
Primary
Concomitant
Coronary Artery Bypass Hospitalization 7/15/2006 Male 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pseudomonas Infection Other Serious 8/4/2005 Female 97 lb 2/9/2007 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 12/27/2006 Female 150 lb 2/9/2007 Consumer Canada
Primary
Concomitant
Depression Hospitalization 9/4/2006 Female 209 lb 2/12/2007 Physician Canada
Primary
Concomitant
Neutropenia Other Serious 12/14/2006 60 Female 128 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vertebral Injury Hospitalization 9/4/2006 Female 209 lb 3/16/2007 Physician Canada
Primary
Concomitant
Sternal Fracture Disability 7/1/2006 61 Female 185 lb 4/12/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 3/6/2007 79 Female 146 lb 5/11/2007 Pharmacist United States
Primary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 8/14/2007 Consumer Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 78 Female 181 lb 9/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 9/1/2007 Female 165 lb 10/5/2007 Physician United States
Primary
Concomitant
Headache Other Serious 6/1/2007 Female 73 lb 10/9/2007 Physician Denmark
Primary
Concomitant
Diplegia Hospitalization 10/1/2007 Female 11/8/2007 Canada
Primary
Concomitant
Diplegia Hospitalization 10/1/2007 Female 11/9/2007 Canada
Primary
Concomitant
Myelitis Transverse Hospitalization 10/1/2007 Female 11/16/2007 Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 12/6/2007 Physician United States
Primary
Concomitant
Headache 9/29/2006 Female 12/10/2007 Physician United States
Primary
Concomitant
Myelitis Transverse Hospitalization 10/1/2007 Female 12/14/2007 Canada
Primary
Concomitant
Blood Sodium Decreased Hospitalization 7/27/2007 Female 146 lb 1/22/2008 United Kingdom
Primary
Concomitant
Injection Site Warmth 1/25/2008 Female 3/15/2008 United States
Primary
Concomitant
Throat Irritation 12/1/2007 Female 214 lb 3/15/2008 United States
Primary
Concomitant
Mobility Decreased 1/1/2008 Female 3/15/2008 United States
Primary
Concomitant
Myelitis Transverse Hospitalization 10/1/2007 Female 182 lb 3/20/2008 Canada
Primary
Concomitant
Shock Haemorrhagic Hospitalization 12/1/2007 Female 90 lb 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
Salpingectomy Other Serious 6/14/2007 Female 132 lb 5/2/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 4/8/2008 Female 115 lb 5/23/2008 Canada
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 6/11/2008 Physician United States
Primary
Concomitant
Accidental Exposure 3/3/2008 Female 164 lb 6/12/2008 Consumer United States
Primary
Concomitant
Swelling Face 3/4/2008 Female 6/12/2008 Other Health Professional United States
Primary
Concomitant
Accidental Exposure 5/30/2008 Female 220 lb 6/13/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/8/2008 Female 115 lb 6/13/2008 Canada
Primary
Secondary
Concomitant
Breast Cancer Other Serious 67 Female 7/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 7/10/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 Female 110 lb 7/11/2008 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 4/8/2008 Female 115 lb 8/15/2008 Canada
Primary
Secondary
Concomitant
Weight Decreased Female 105 lb 9/12/2008 Consumer United States
Primary
Concomitant
Nasopharyngitis 6/1/2008 Female 160 lb 9/12/2008 United States
Primary
Concomitant
Weight Increased 2/1/2008 Female 113 lb 9/12/2008 Consumer United States
Primary
Concomitant
Underdose 27 Male 120 lb 9/12/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 7/10/2008 Female 111 lb 9/12/2008 Consumer United States
Primary
Concomitant
Hypoaesthesia 7/15/2008 Female 209 lb 9/12/2008 United States
Primary
Concomitant
Pneumonia Life Threatening 4/23/2008 Female 115 lb 10/13/2008 Canada
Primary
Secondary
Concomitant
Tinea Versicolour Other Serious 1/1/2007 Female 157 lb 11/12/2008 United Kingdom
Primary
Concomitant
Respiratory Failure Death 10/1/2008 Male 208 lb 11/24/2008 Canada
Primary
Concomitant
Respiratory Failure Death 10/1/2008 Male 208 lb 12/11/2008 Canada
Primary
Concomitant
Uterine Enlargement 6/1/2008 Female 180 lb 12/12/2008 Puerto Rico
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 6/1/2008 Male 188 lb 12/12/2008 Consumer United States
Primary
Concomitant
Nasopharyngitis 10/2/2008 Female 128 lb 12/12/2008 United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 11/15/2008 Female 108 lb 3/10/2009 United Kingdom
Primary
Concomitant
Urinary Tract Infection Bacterial Female 269 lb 4/13/2009 United States
Primary
Concomitant
Pruritus Other Serious 9/1/2008 Female 165 lb 8/13/2009 Consumer Argentina
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/14/2009 62 Male 8/17/2009 Physician Japan
Primary
Secondary
Concomitant
Incorrect Dose Administered 3/25/2007 Male 180 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Reaction 10/1/2006 Female 170 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation 3/3/2008 Female 164 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation 5/30/2008 Female 220 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation 7/10/2008 Female 111 lb 9/12/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 1/1/2009 Female 144 lb 10/6/2009 Physician United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Life Threatening 7/1/2009 61 Female 137 lb 6/8/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Potassium Increased Hospitalization 11/9/2009 81 Male 203 lb 6/16/2010 United States
Primary
Concomitant
Pain 8/1/2009 65 Female 150 lb 9/14/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 4/30/2010 74 Male 9/16/2010 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 2/22/2010 48 Female 161 lb 10/27/2010 Other Health Professional United States
Primary
Concomitant
Oropharyngeal Pain Hospitalization 10/22/2010 70 Female 11/11/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/1/2009 12/19/2010 Consumer United States
Primary
Concomitant
Injection Site Pruritus 3/11/2010 12/19/2010 Consumer United States
Primary
Concomitant
Skin Laceration 3/15/2010 12/19/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection 12/21/2010 Consumer United States
Primary
Concomitant
Alopecia 9/10/2009 12/21/2010 Consumer United States
Primary
Concomitant
Nasopharyngitis 3/1/2010 12/22/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 8/11/2010 12/23/2010 Consumer United States
Primary
Concomitant
Lymphadenopathy 12/23/2010 Consumer United States
Primary
Concomitant
Vision Blurred 6/1/2010 12/23/2010 Pharmacist United States
Primary
Concomitant
Oropharyngeal Pain 12/23/2010 Consumer United States
Primary
Concomitant
Multiple Allergies Other Serious 2/22/2010 48 Female 161 lb 12/15/2010 Other Health Professional United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 9/8/2010 49 Female 161 lb 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/9/2010 66 Female 160 lb 1/6/2011 Physician Canada
Primary
Secondary
Concomitant
Hypertension Life Threatening 3/25/2010 62 Male 180 lb 2/8/2011 Other Health Professional United States
Primary
Concomitant
Immunosuppression Life Threatening 3/26/2010 62 Male 180 lb 2/25/2011 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 3/7/2009 62 Male 274 lb 5/6/2011 Physician United States
Primary
Concomitant
Cholecystitis Hospitalization 8/19/2010 70 Male 6/17/2011 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/20/2011 52 Female 181 lb 6/24/2011 Physician Belgium
Primary
Concomitant
Arterial Thrombosis Hospitalization 4/20/2011 52 Female 181 lb 7/7/2011 Physician Belgium
Primary
Concomitant
Cholecystitis Hospitalization 8/19/2010 70 Male 7/28/2011 Physician Netherlands
Primary
Secondary
Concomitant
Coronary Artery Embolism Hospitalization 4/20/2011 52 Female 181 lb 7/29/2011 Physician Belgium
Primary
Concomitant
Psoriasis Other Serious 1/1/2008 68 Male 7/29/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/20/2011 52 Female 181 lb 8/12/2011 Physician Belgium
Primary
Concomitant
Candidiasis Other Serious 5/1/2009 44 Female 156 lb 8/26/2011 Physician United States
Primary
Concomitant
Cardiovascular Disorder Hospitalization 9/1/2008 36 Female 9/22/2011 Physician United States
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2011 70 Female 9/28/2011 Physician Japan
Primary
Concomitant
Atrial Fibrillation Other Serious 8/27/2011 71 Female 9/30/2011 Physician Japan
Primary
Concomitant
Joint Destruction 7/5/2011 68 Female 165 lb 11/6/2011 Consumer United States
Primary
Concomitant
Diverticulitis Hospitalization 10/30/2011 67 Female 11/23/2011 Physician United States
Primary
Secondary
Concomitant
Catheter Site Infection Hospitalization 9/8/2010 49 Female 161 lb 12/13/2011 Physician United States
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 12/21/2009 47 Female 99 lb 12/19/2011 Japan
Primary
Secondary
Device Related Infection Hospitalization 12/6/2011 50 Female 161 lb 12/22/2011 Physician United States
Primary
Secondary
Concomitant
Dizziness 9/7/2011 50 Male 153 lb 1/5/2012 Pharmacist United States
Primary
Concomitant
Bladder Dilatation Hospitalization 9/1/2011 34 Female 136 lb 1/12/2012 Consumer United States
Primary
Concomitant
Joint Stiffness Other Serious 10/1/2011 48 Female 150 lb 1/27/2012 Consumer Canada
Primary
Concomitant
Cryptococcosis Hospitalization 8/20/2011 72 Female 90 lb 1/27/2012 Consumer Japan
Primary
Secondary
Concomitant
Arthralgia 7/1/2010 64 Female 1/27/2012 Consumer United States
Primary
Concomitant
Anaemia 12/1/2010 49 Female 108 lb 1/27/2012 Consumer United States
Primary
Secondary
Concomitant
Arthralgia 8/1/2010 47 Male 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Haematoma 67 Female 1/28/2012 Consumer United States
Primary
Concomitant
Pain Hospitalization 2/2/2010 38 Female 245 lb 1/31/2012 Lawyer United States
Primary
Concomitant
Disseminated Intravascular Coagulation Death 8/20/2011 72 Female 90 lb 2/2/2012 Physician Japan
Primary
Secondary
Concomitant
Thyroid Cancer Hospitalization 9/1/2011 34 Female 136 lb 2/21/2012 Physician United States
Primary
Concomitant
Bone Graft Hospitalization 7/13/2006 59 Female 250 lb 2/29/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cryptococcosis Hospitalization 8/20/2011 72 Female 90 lb 3/27/2012 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Hospitalization 11/19/2011 29 Female 5/11/2012 Physician Belgium
Primary
Concomitant
Crohn's Disease Hospitalization 11/19/2011 29 Female 5/15/2012 Physician Belgium
Primary
Concomitant
Injection Site Haematoma 5/1/2012 61 Female 6/5/2012 Physician United States
Primary
Concomitant
Arthritis Other Serious 1/1/2012 54 Female 155 lb 6/15/2012 Consumer United States
Primary
Concomitant
Polyarteritis Nodosa Other Serious 12/1/2011 79 Female 6/26/2012 Physician Japan
Primary
Concomitant
Cryptococcosis Hospitalization 8/20/2011 72 Female 90 lb 6/29/2012 Consumer Japan
Primary
Secondary
Concomitant
Polyarteritis Nodosa Other Serious 12/1/2011 79 Female 6/29/2012 Physician Japan
Primary
Concomitant
Kidney Infection Hospitalization 5/26/2012 54 Female 292 lb 7/5/2012 Consumer United States
Primary
Concomitant
Headache Other Serious 6/19/2012 54 Female 185 lb 7/6/2012 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 58 Female 7/5/2012 Other Health Professional United States
Primary
Concomitant
Nephrolithiasis Hospitalization 5/26/2012 54 Female 292 lb 7/30/2012 Physician United States
Primary
Concomitant
Polyarteritis Nodosa Other Serious 12/1/2011 79 Female 7/31/2012 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 7/15/2012 66 Female 150 lb 8/8/2012 Consumer United States
Primary
Concomitant
Iritis Other Serious 6/19/2012 54 Female 185 lb 8/21/2012 Consumer United States
Primary
Concomitant
Nausea 7/15/2012 66 Female 150 lb 8/23/2012 Consumer United States
Primary
Concomitant
Drug Hypersensitivity Other Serious 12/1/2008 47 Female 205 lb 8/27/2012 Consumer United States
Primary
Concomitant

Drug Data