Methotrexate combined with Trazodone Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sudden Death Death 6/3/2005 1/2/2006 Physician United States
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 1/8/2006 Female 135 lb 1/26/2006 Canada
Primary
Concomitant
Knee Arthroplasty Other Serious Male 225 lb 3/23/2006 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 12/1/2005 Female 4/24/2006 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9/1/2005 Female 125 lb 5/11/2006 Physician United States
Primary
Concomitant
Thrombophlebitis Other Serious 11/4/2005 67 Female 163 lb 5/1/2006 Consumer United States
Primary
Concomitant
Candidiasis Hospitalization 9/16/2005 Female 178 lb 5/25/2006 Physician United States
Primary
Concomitant
Streptococcal Abscess Hospitalization 7/1/2005 Male 6/1/2006 Physician United States
Primary
Concomitant
Hypoaesthesia Hospitalization 5/3/2006 63 Female 134 lb 6/9/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2003 37 Female 6/28/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2003 37 Female 6/22/2006 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 5/3/2006 63 Female 132 lb 6/29/2006 Consumer United States
Primary
Concomitant
Vesical Fistula Other Serious 6/1/2006 Female 7/6/2006 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 8/9/2006 68 Female 8/21/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization 8/9/2006 68 Female 8/23/2006 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 7/11/2006 Female 103 lb 8/31/2006 Consumer United States
Primary
Concomitant
Uterine Cancer Other Serious 1/1/2003 Female 9/6/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 8/15/2001 Male 9/6/2006 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Death 5/13/2004 Female 100 lb 9/6/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2003 Female 9/7/2006 Physician United States
Primary
Concomitant
Joint Injury Other Serious 6/1/2006 Male 9/8/2006 Consumer Canada
Primary
Concomitant
Sepsis Death Male 9/11/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 12/1/2005 Female 10/3/2006 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 6/1/2006 Female 203 lb 10/3/2006 Consumer United States
Primary
Concomitant
Heart Rate Increased 5/15/2006 55 Female 7/31/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 9/30/2006 60 Female 10/9/2006 Consumer United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 4/29/2004 Female 141 lb 11/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 4/29/2004 Female 141 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 45 Female 137 lb 11/9/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 2/1/2000 63 Male 11/21/2006 United States
Primary
Concomitant
Pancytopenia Other Serious 6/20/2006 83 Male 168 lb 7/28/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 8/14/2006 Male 160 lb 12/4/2006 Physician United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 1/1/2006 Female 144 lb 12/13/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 10/1/2006 48 Female 140 lb 12/11/2006 United States
Primary
Concomitant
Localised Infection 6/8/2006 Female 12/21/2006 Consumer United States
Primary
Concomitant
Infusion Related Reaction 7/1/2006 69 Female 99 lb 12/22/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 9/30/2006 60 Female 1/8/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 10/1/2006 48 Female 140 lb 1/9/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 153 lb 1/19/2007 Physician United States
Primary
Concomitant
Device Failure Other Serious 6/1/2006 Male 1/22/2007 Consumer Canada
Primary
Concomitant
Visual Disturbance Other Serious 7/6/2006 42 Female 1/26/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Toothache Other Serious 1/1/2007 49 Female 162 lb 2/13/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 153 lb 2/20/2007 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 2/1/2006 Female 170 lb 2/28/2007 Physician United States
Primary
Concomitant
Bronchitis Other Serious Female 250 lb 4/5/2007 Physician United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/26/2007 Male 173 lb 4/11/2007 Physician United States
Primary
Concomitant
Toothache Other Serious 1/1/2007 49 Female 162 lb 6/21/2007 Physician United States
Primary
Concomitant
Bladder Cancer Other Serious 6/18/2007 Female 190 lb 6/28/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2007 83 Female 7/10/2007 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 7/1/2007 Female 155 lb 8/14/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 Male 211 lb 9/19/2007 Physician United States
Primary
Concomitant
Tremor Hospitalization 5/8/2000 52 Female 291 lb 9/24/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 2/21/2007 Female 260 lb 10/5/2007 Canada
Primary
Concomitant
Swelling Face Other Serious 1/1/2007 Female 191 lb 10/16/2007 United States
Primary
Concomitant
Drug Dependence Death 10/6/2007 40 Female 198 lb 11/13/2007 Consumer United States
Primary
Concomitant
Syncope Life Threatening 7/11/2007 Female 190 lb 11/21/2007 Physician United States
Primary
Concomitant
Osteopenia Other Serious 1/1/2002 Female 116 lb 12/6/2007 Physician United States
Primary
Concomitant
Drug Ineffective 1/1/2005 Female 101 lb 12/14/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection 9/13/2007 Female 147 lb 12/14/2007 Physician United States
Primary
Concomitant
Overdose Hospitalization 10/16/2007 Female 180 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 12/18/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 12/27/2007 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 8/22/2007 Female 226 lb 12/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/22/2007 Female 226 lb 1/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 351 lb 1/21/2008 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 8/22/2007 Female 226 lb 2/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Balance Disorder Other Serious 2/1/2008 Female 130 lb 2/22/2008 United States
Primary
Concomitant
Osteonecrosis Required Intervention 8/25/2004 59 Female 1/16/2008 Physician United States
Primary
Concomitant
Soft Tissue Disorder Required Intervention 3/1/2003 63 Female 1/17/2008 United States
Primary
Concomitant
Balance Disorder Other Serious 2/1/2008 Female 130 lb 2/28/2008 United States
Primary
Concomitant
Injection Site Irritation 11/29/2007 Female 399 lb 3/14/2008 Consumer United States
Primary
Concomitant
Pain 1/18/2008 Female 149 lb 3/15/2008 Physician United States
Primary
Concomitant
Ovarian Cyst 3/21/2008 Female 206 lb 3/24/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Life Threatening 3/8/2008 48 Male 248 lb 3/28/2008 Physician United States
Primary
Concomitant
Raynaud's Phenomenon 2/1/2006 54 Female 4/3/2007 Physician United States
Primary
Concomitant
Thromboangiitis Obliterans Hospitalization 3/7/2008 Female 201 lb 4/28/2008 Physician United States
Primary
Concomitant
Sinusitis Other Serious 3/1/2006 Female 250 lb 5/20/2008 United States
Primary
Concomitant
Paraesthesia Hospitalization 4/24/2008 Female 204 lb 5/23/2008 Physician United States
Primary
Concomitant
Gastritis Hospitalization 4/26/2008 Female 204 lb 6/2/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 11/1/2007 Female 89 lb 6/11/2008 Consumer United States
Primary
Concomitant
Overdose Hospitalization 10/16/2007 Female 180 lb 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Nasopharyngitis 3/6/2008 Female 285 lb 6/12/2008 United States
Primary
Concomitant
Pain 1/1/2008 Female 118 lb 6/12/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased 4/1/2006 Female 109 lb 6/12/2008 United States
Primary
Concomitant
Viral Infection 1/1/2008 Female 113 lb 6/13/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 1/1/2007 Female 286 lb 6/13/2008 United States
Primary
Concomitant
Sinusitis 12/1/2007 Female 138 lb 6/13/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 5/1/2008 Female 147 lb 6/13/2008 Consumer United States
Primary
Concomitant
Uveitis Other Serious 1/1/2008 Female 6/20/2008 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis 70 Female 6/30/2008 Consumer United States
Primary
Concomitant
Nasopharyngitis 55 Female 205 lb 6/30/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 2/1/2008 60 Female 7/3/2008 Consumer United States
Primary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
Wheezing Hospitalization 11/13/2002 Male 7/21/2008 Other Health Professional United States
Primary
Concomitant
Post Herpetic Neuralgia Hospitalization 8/2/2008 57 Female 137 lb 8/4/2008 Other Health Professional United States
Primary
Concomitant
Uveitis Other Serious 1/1/2008 Female 152 lb 8/14/2008 Other Health Professional United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 4/30/2007 68 Female 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 5/1/2006 Female 250 lb 9/11/2008 United States
Primary
Concomitant
Fatigue 6/2/2008 Female 108 lb 9/12/2008 United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 6/5/2008 Female 240 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Haemorrhage 6/26/2008 Female 185 lb 9/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Factor Increased 5/1/2008 190 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Female 130 lb 9/12/2008 Physician United States
Primary
Concomitant
Underdose 6/1/2008 Female 9/12/2008 Pharmacist United States
Primary
Concomitant
B-cell Lymphoma Required Intervention 8/19/2008 Female 185 lb 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Death Death Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Swelling Face Other Serious 8/26/2008 18 Female 201 lb 10/24/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2008 Female 10/28/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 11/1/2007 Female 11/3/2008 Physician United States
Primary
Concomitant
Asthma Other Serious 4/30/2007 68 Female 11/26/2008 Consumer United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 1/1/2008 Female 159 lb 12/2/2008 Physician United States
Primary
Concomitant
Joint Warmth 8/1/2008 Female 12/8/2008 Physician United States
Primary
Concomitant
Joint Stiffness 1/1/2007 Male 252 lb 12/8/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 9/2/2008 Female 130 lb 12/9/2008 Physician United States
Primary
Concomitant
Asthenia 11/24/2008 Female 139 lb 12/10/2008 Physician United States
Primary
Concomitant
Procedural Complication 8/30/2008 Male 300 lb 12/12/2008 Consumer United States
Primary
Concomitant
Localised Infection 9/4/2008 Female 160 lb 12/12/2008 United States
Primary
Concomitant
Swelling Face 1/1/2006 Female 100 lb 12/12/2008 Consumer United States
Primary
Concomitant
Cough 9/12/2008 Female 150 lb 12/12/2008 United States
Primary
Concomitant
Rash Pruritic 4/1/2008 Female 265 lb 12/12/2008 Consumer United States
Primary
Concomitant
Oligomenorrhoea 7/21/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Pyrexia 11/10/2008 Female 12/12/2008 United States
Primary
Concomitant
Incorrect Dose Administered 11/24/2008 Female 149 lb 12/12/2008 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 4/1/2004 Female 167 lb 1/7/2009 Physician United States
Primary
Concomitant
Swelling Face Other Serious 8/26/2008 18 Female 201 lb 1/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 Female 1/5/2009 Consumer United States
Primary
Concomitant
Yellow Skin 1/1/2008 Female 1/12/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 10/1/2006 Female 167 lb 1/15/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Death Death 1/26/2009 Female 134 lb 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 7/1/2003 Male 271 lb 2/13/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/20/2009 Physician United States
Primary
Concomitant
Pneumonia Death 1/1/2009 Female 134 lb 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 Female 2/13/2009 Consumer United States
Primary
Concomitant
Migraine With Aura Other Serious 1/1/2004 Female 250 lb 3/6/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/21/2009 Male 190 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Death 6/3/2005 Male 226 lb 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Speech Disorder 1/20/2009 Female 210 lb 3/13/2009 Consumer United States
Primary
Concomitant
Nausea 7/13/2008 Female 155 lb 3/14/2009 Consumer United States
Primary
Concomitant
Vomiting 11/1/2008 Female 155 lb 3/14/2009 Consumer United States
Primary
Concomitant
Skin Lesion 1/15/2009 Female 140 lb 3/14/2009 United States
Primary
Concomitant
Pneumonia Death 1/1/2009 Female 134 lb 3/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Yellow Skin 1/1/2008 Female 4/9/2009 Physician United States
Primary
Concomitant
Nausea Other Serious 8/1/2008 Female 234 lb 5/19/2009 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 5/6/2009 Female 196 lb 5/22/2009 Physician United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 59 Female 5/26/2009 Lawyer United States
Primary
Concomitant
Swelling Face Other Serious 8/26/2008 18 Female 201 lb 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 1/2/2009 51 Female 148 lb 5/18/2009 Consumer United States
Primary
Concomitant
Pyrexia 11/10/2008 Female 6/11/2009 United States
Primary
Concomitant
Incorrect Dose Administered 2/28/2009 Female 140 lb 6/11/2009 Consumer Puerto Rico
Primary
Concomitant

Drug Data