Filgrastim combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Dehiscence Hospitalization 63 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Wound Dehiscence Hospitalization 63 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 3/10/2006 Physician Japan
Primary
Secondary
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Acute Graft Versus Host Disease Hospitalization 10/20/2006 46 Male 3/26/2007 Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2007 Male 5/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 35 Male 6/19/2007 Japan
Primary
Secondary
Viral Dna Test Positive Other Serious 46 Male 6/24/2007 Japan
Primary
Secondary
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 7/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/7/2007 39 Male 7/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/28/2007 34 Female 7/16/2007 Japan
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 4/13/2007 49 Male 7/16/2007 Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 1/8/2007 40 Female 7/19/2007 Japan
Primary
Secondary
Concomitant
Vomiting Death 2/25/2007 13 Female 8/1/2007 Japan
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/7/2007 39 Male 8/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3 Male 35 lb 8/28/2007
Primary
Secondary
Cytomegalovirus Viraemia Hospitalization 6/11/2007 60 Male 12/10/2007 Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 37 Male 12/20/2007 Physician Turkey
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 11/1/2006 53 Male 12/19/2007 Other Health Professional Japan
Primary
Concomitant
Mucosal Inflammation Hospitalization 37 Male 12/28/2007 Physician Turkey
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 3/21/2007 20 Male 1/3/2008 Japan
Primary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 9/24/2007 46 Female 146 lb 1/24/2008 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 8/8/1998 42 Male 1/30/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/10/1999 40 Male 1/30/2008 United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/2/2001 32 Male 1/30/2008 United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2007 54 Female 3/6/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 4/19/2007 16 Female 3/6/2008 Japan
Primary
Concomitant
Viraemia Other Serious 5/23/2007 31 Male 3/6/2008 Japan
Primary
Secondary
Concomitant
Wolff-parkinson-white Syndrome Hospitalization 8/6/2007 80 Male 3/6/2008 Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 168 lb 5/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 167 lb 4/25/2008 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 65 Male 5/15/2008 Other Health Professional Japan
Primary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 167 lb 5/7/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Death 8/8/1998 7/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Pain Other Serious 8/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
Choriomeningitis Lymphocytic Hospitalization 15 Female 10/17/2008 Physician United States
Primary
Concomitant
Choriomeningitis Lymphocytic Hospitalization 15 Female 10/20/2008 Physician United States
Primary
Concomitant
Clostridium Difficile Colitis 22 Female 2/19/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/18/2008 46 Male 2/18/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/18/2008 46 Male 3/2/2009 Other Health Professional Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 57 Male 3/18/2009
Primary
Concomitant
Skin Ulcer Other Serious 68 Male 3/18/2009
Primary
Concomitant
Neutropenic Colitis Other Serious 61 Female 5/15/2009
Primary
Secondary
Concomitant
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 5/15/2009 Physician
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 5/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 69 Female 5/29/2009
Primary
Secondary
Concomitant
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 20 lb 6/1/2009 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/24/2009 50 Male 160 lb 7/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/17/2009 79 Female 8/5/2009 Physician Italy
Primary
Concomitant
Constipation Hospitalization 2/8/2008 Female 167 lb 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 2/8/2008 Female 167 lb 11/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Death Female 116 lb 12/31/2009 Pharmacist United States
Primary
Concomitant
Septic Shock Death Female 116 lb 1/19/2010 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/7/2007 39 Male 1/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/7/2007 39 Male 1/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 Male 1/28/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 1/28/2010 Physician United States
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Hepatic Lesion Hospitalization 2/8/2008 66 Female 168 lb 4/5/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/16/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/20/2010 United States
Primary
Concomitant
Pyrexia Life Threatening 4/7/2010 68 Male 157 lb 4/15/2010 Other Health Professional United States
Primary
Concomitant
Skin Toxicity Death 4/30/2010 Physician United Kingdom
Primary
Secondary
Weight Decreased Other Serious 1/1/2004 5/10/2010 United States
Primary
Concomitant
Neutropenia Other Serious 3/1/2008 73 Female 5/20/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/15/2010 United States
Primary
Concomitant
Convulsion Other Serious 3 Female 6/16/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/17/2010 United States
Primary
Concomitant
Neutropenia Life Threatening 3/1/2008 73 Female 6/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 1/1/2009 61 Female 6/15/2010 Physician Germany
Primary
Secondary
Concomitant
Convulsion Other Serious 3 Female 6/22/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 7/22/2010 14 Female 97 lb 10/22/2010 Physician Japan
Primary
Concomitant
Sepsis Death 9/13/2010 76 Female 148 lb 10/28/2010 Physician United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 12/27/2008 52 Male 152 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 7/17/2009 28 Male 110 lb 11/23/2010 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Other Serious 7/17/2009 28 Male 110 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 3/15/2010 54 Female 95 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/12/2009 76 Male 119 lb 12/23/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/12/2009 76 Male 119 lb 12/29/2010 Physician Japan
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 11/28/2009 73 Male 112 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Death 10/10/2009 72 Male 112 lb 12/30/2010 Physician Japan
Primary
Concomitant
Pyrexia Death 11/28/2009 73 Male 112 lb 1/3/2011 Physician Japan
Primary
Concomitant
Death Death 41 Male 1/3/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 45 Male 1/4/2011 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Death Other Serious 39 Female 1/4/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 11/26/2010 35 Male 110 lb 1/4/2011 Physician Japan
Primary
Concomitant
Death Other Serious 38 Male 1/5/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 38 Female 1/5/2011 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 46 Female 1/5/2011 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 40 Male 1/5/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/6/2011 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Adult T-cell Lymphoma/leukaemia Death Female 126 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Premature Baby Hospitalization 12/25/2003 Female 4 lb 1/18/2011 Physician France
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2009 18 Male 137 lb 1/24/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Hospitalization 9/30/2009 18 Female 137 lb 1/28/2011 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 7/22/2010 14 Female 97 lb 2/14/2011 Physician Japan
Primary
Concomitant
Sepsis Other Serious 9/10/2009 18 Male 137 lb 2/15/2011 Physician Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 43 Female 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 66 Female 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 38 Male 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 72 Male 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Disease Progression Death 70 Male 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 76 Female 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 29 Female 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 52 Female 2/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 56 Female 2/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 48 Female 2/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Multi-organ Failure Death 4/25/2010 43 Male 168 lb 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Enterocolitis Hospitalization 3/30/2009 64 Female 112 lb 3/4/2011 Consumer Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 25 Female 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 46 Male 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Other Serious 58 Female 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/24/2010 19 Male 115 lb 3/10/2011 Physician Japan
Primary
Concomitant
Anxiety Death 3/8/2011 15 Female 144 lb 3/23/2011 Physician United States
Primary
Secondary
Pneumonia Bacterial Other Serious 1/29/2010 52 Male 132 lb 3/24/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Meninges Other Serious 1/1/2004 3/25/2011 Physician United States
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 18 Female 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 25 Female 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 4/25/2010 43 Male 168 lb 4/1/2011 Physician United States
Primary
Secondary
Concomitant
Hepatitis Fulminant Other Serious 58 Female 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 4/25/2010 43 Male 168 lb 4/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 4/14/2011 Physician United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Death 4/15/2011 Physician United States
Primary
Secondary
Rash Hospitalization 3/15/2010 54 Female 95 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/4/2011 Male 4/28/2011 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/4/2011 Male 5/4/2011 Other Health Professional United States
Primary
Concomitant
Hyperbilirubinaemia Other Serious 11/16/2010 58 Female 117 lb 5/13/2011 Consumer United States
Primary
Secondary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Death 3/8/2011 15 Female 144 lb 5/24/2011 Physician United States
Primary
Secondary
Candida Test Positive Hospitalization 3/12/2010 54 Female 95 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 10/26/2009 52 Male 121 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Mycosis Other Serious 3/2/2010 63 Male 130 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/1991 16 Female 6/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 1/29/2010 52 Male 132 lb 6/20/2011 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 2/10/2010 23 Male 117 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data