Lotrel combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Arthralgia Other Serious 2/1/2005 Female 214 lb 1/20/2006 United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 9/1/2005 Female 3/1/2006 Physician United States
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 11/9/2005 64 Female 2/22/2006 Consumer United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Life Threatening 3/27/2006 Female 116 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Thalamic Infarction Hospitalization 3/17/2004 57 Male 5/18/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/20/2006 70 Female 117 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 10/1/2005 Female 5/26/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death Female 6/12/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 Female 137 lb 8/4/2006 Consumer United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Ureteral Stent Insertion Hospitalization 7/1/2005 Female 156 lb 9/11/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 5/18/2004 Female 155 lb 9/26/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 11/1/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 11/6/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 5/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Mycosis Fungoides Other Serious 4/19/2006 Male 203 lb 12/22/2006 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 1/1/2006 68 Female 4/9/2007 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 1/1/2006 68 Female 4/18/2007 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 5/3/2007 Physician United States
Primary
Concomitant
Somnolence Other Serious 5/1/2007 53 Female 210 lb 5/24/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 4/26/2007 57 Female 6/25/2007 Consumer United States
Primary
Concomitant
Prostate Cancer Other Serious 9/1/2006 Male 185 lb 7/19/2007 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 6/1/2007 Male 180 lb 7/23/2007 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 6/20/2006 84 Female 8/4/2007 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 5/8/2000 52 Female 291 lb 9/24/2007 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 10/22/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/2/2002 Female 10/23/2007 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 1/1/2006 68 Female 10/23/2007 Physician United States
Primary
Concomitant
Tuberculosis Skin Test Positive 5/1/2007 Female 164 lb 12/12/2007 Physician United States
Primary
Concomitant
Depression 9/20/2007 Female 150 lb 12/14/2007 Consumer United States
Primary
Concomitant
Arthralgia Female 201 lb 12/14/2007 Consumer United States
Primary
Concomitant
Heart Rate Increased 10/1/2007 Male 230 lb 12/14/2007 Consumer United States
Primary
Concomitant
Swelling Face 1/1/2007 Female 309 lb 12/15/2007 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 12/18/2007 Physician United States
Primary
Concomitant
Urinary Tract Inflammation Required Intervention 8/21/2007 69 Female 168 lb 1/12/2008 Consumer United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 1/24/2008 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 1/1/2006 68 Female 2/5/2008 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 3/14/2005 68 Female 119 lb 2/15/2008 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 2/28/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 60 Female 4/2/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased 4/15/2008 Female 240 lb 6/11/2008 United States
Primary
Concomitant
Pain 11/12/2007 Female 228 lb 6/12/2008 Consumer United States
Primary
Concomitant
Paraesthesia 5/1/2008 Female 225 lb 6/13/2008 United States
Primary
Concomitant
Injection Site Irritation 1/15/2008 Female 158 lb 6/13/2008 United States
Primary
Concomitant
Influenza Like Illness Other Serious 9/1/2006 62 Female 220 lb 6/27/2008 Physician United States
Primary
Concomitant
Influenza Like Illness Other Serious 9/1/2006 62 Female 220 lb 7/15/2008 United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2006 62 Female 220 lb 7/24/2008 United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Hospitalization 4/20/2006 Female 8/19/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased 4/1/2008 Female 236 lb 9/12/2008 United States
Primary
Concomitant
Musculoskeletal Stiffness 1/1/2007 Male 200 lb 9/12/2008 Consumer United States
Primary
Concomitant
Tremor 5/1/2008 Female 210 lb 9/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2005 Female 273 lb 9/12/2008 Physician United States
Primary
Concomitant
Syncope Hospitalization 6/1/2008 137 lb 9/12/2008 Consumer United States
Primary
Concomitant
Fungal Infection 3/10/2008 56 Female 9/25/2008 Consumer United States
Primary
Concomitant
Vulval Cancer Other Serious 9/16/2008 Female 157 lb 11/20/2008 Puerto Rico
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 11/27/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 2/28/2005 Female 167 lb 12/5/2008 Physician United States
Primary
Concomitant
Tremor 5/1/2008 Female 210 lb 12/12/2008 Consumer United States
Primary
Concomitant
Wound Secretion 9/11/2008 Male 195 lb 12/12/2008 United States
Primary
Concomitant
Therapeutic Response Decreased 10/16/2007 Male 210 lb 12/15/2008 Physician United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 12/19/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 2/28/2005 Female 167 lb 12/23/2008 Physician United States
Primary
Concomitant
Lung Cancer Metastatic Death 11/1/2008 Female 139 lb 1/23/2009 Physician United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 2/23/2009 Physician United States
Primary
Concomitant
Injection Site Pain 1/1/2007 Female 3/14/2009 United States
Primary
Concomitant
Hypophagia 11/11/2008 Male 190 lb 3/14/2009 Consumer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 2/2/2009 Male 212 lb 6/11/2009 United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2009 Female 147 lb 6/11/2009 Physician United States
Primary
Concomitant
Injection Site Pain 3/6/2009 Female 156 lb 6/11/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 5/25/2009 Female 107 lb 6/12/2009 Consumer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 6/8/2009 Female 145 lb 6/17/2009 Consumer United States
Primary
Concomitant
Synovitis Other Serious 1/1/2006 Female 123 lb 6/18/2009 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Female 115 lb 9/3/2009 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 7/16/2009 Male 9/10/2009 Physician United States
Primary
Concomitant
Polymyositis Hospitalization Male 9/10/2009 Physician United States
Primary
Concomitant
Injection Site Pain 4/1/2007 Female 229 lb 9/11/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2007 Female 9/19/2009 United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 7/16/2009 Male 9/30/2009 Physician United States
Primary
Concomitant
Sinusitis Other Serious Male 11/17/2009 Consumer United States
Primary
Concomitant
Confusional State Other Serious 8/1/2009 Female 99 lb 1/12/2010 Physician United States
Primary
Concomitant
Viral Infection 8/1/2009 Female 312 lb 1/29/2010 United States
Primary
Concomitant
Paraesthesia 9/21/2009 Female 1/30/2010 United States
Primary
Concomitant
Prostate Cancer Life Threatening 12/9/2008 Male 212 lb 2/11/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 55 Female 2/22/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 8/1/2001 62 Female 218 lb 2/25/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/26/2010 Pharmacist United States
Primary
Concomitant
Confusional State Other Serious 8/1/2009 Female 99 lb 3/5/2010 United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 3/17/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 4/20/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 4/30/2009 45 Female 210 lb 4/26/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 2/1/2010 66 Female 4/30/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/19/2010 United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/28/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 6/2/2010 Pharmacist United States
Primary
Concomitant
Metastasis Hospitalization 4/6/2010 Male 6/23/2010 Physician United States
Primary
Secondary
Concomitant
Metastasis Hospitalization 4/6/2010 Male 7/8/2010 Physician United States
Primary
Secondary
Concomitant
Poor Quality Sleep 8/1/2007 79 Female 135 lb 7/14/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 2/1/2010 66 Female 7/16/2010 Consumer United States
Primary
Concomitant
Metastasis Hospitalization 4/6/2010 60 Male 7/29/2010 Physician United States
Primary
Secondary
Concomitant
Renal Mass Hospitalization Female 220 lb 9/3/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 9/13/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 10/20/2010 Pharmacist United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 9/1/2010 55 Male 240 lb 10/26/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 11/9/2010 Pharmacist United States
Primary
Concomitant
Oedema Peripheral 12/15/2010 Consumer United States
Primary
Concomitant
Humerus Fracture 7/1/2010 56 Female 11/6/2010 Consumer United States
Primary
Concomitant
Renal Mass Hospitalization 1/1/2010 59 Female 220 lb 1/5/2011 Consumer United States
Primary
Concomitant
Dyspepsia Hospitalization 11/17/2010 60 Female 175 lb 1/5/2011 Consumer United States
Primary
Concomitant
Joint Stiffness 2/26/2010 62 Female 1/28/2011 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 2/19/2010 52 Female 230 lb 1/28/2011 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 9/15/2010 52 Male 1/29/2011 Consumer United States
Primary
Concomitant
Anticoagulation Drug Level Below Therapeutic Hospitalization 7/30/2003 48 Female 2/11/2011 Pharmacist United States
Primary
Concomitant
Insomnia Hospitalization 7/30/2003 48 Female 2/23/2011 Other Health Professional United States
Primary
Concomitant
Osteoporotic Fracture Other Serious Female 166 lb 4/15/2011 Consumer United States
Primary
Concomitant
Osteoporotic Fracture Other Serious 2/1/2011 76 Female 166 lb 4/18/2011 Consumer United States
Primary
Concomitant
Atelectasis Other Serious 1/1/2004 48 Female 4/7/2011 Physician United States
Primary
Concomitant
Arthropathy Other Serious 1/1/2004 48 Female 4/27/2011 Pharmacist United States
Primary
Concomitant
Breast Cancer Other Serious 9/3/2008 53 Female 179 lb 5/10/2011 Physician United States
Primary
Concomitant
Breast Cancer Stage Iii Other Serious 9/3/2008 53 Female 179 lb 6/17/2011 Physician United States
Primary
Concomitant
Ethmoid Sinus Surgery Other Serious 1/1/2001 67 Female 7/13/2011 Consumer United States
Primary
Secondary
Concomitant
Oral Pain Other Serious 5/4/2011 54 Female 150 lb 8/2/2011 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 7/1/2011 63 Female 180 lb 8/4/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 6/1/2011 85 Female 8/2/2011 Consumer United States
Primary
Concomitant
Intestinal Polyp Other Serious 1/1/2004 48 Female 8/11/2011 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/1/2011 85 Female 9/7/2011 Consumer United States
Primary
Concomitant
Neuritis Hospitalization 2/1/2011 76 Female 166 lb 9/12/2011 Physician United States
Primary
Concomitant
Constipation Hospitalization 6/1/2011 85 Female 132 lb 9/30/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 7/31/2011 49 Female 220 lb 11/6/2011 Consumer United States
Primary
Concomitant
Asphyxia Other Serious 6/1/2011 55 Female 143 lb 11/16/2011 Pharmacist Puerto Rico
Primary
Concomitant
Joint Swelling 1/1/2011 50 Male 1/27/2012 Consumer United States
Primary
Concomitant
Toothache 1/1/2007 65 Male 1/27/2012 Consumer United States
Primary
Concomitant
Gait Disturbance Male 1/28/2012 Consumer Puerto Rico
Primary
Concomitant
Scab 1/1/2011 56 Male 280 lb 1/28/2012 Physician United States
Primary
Concomitant
Nausea 5/2/2011 49 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Reaction 7/1/2010 62 Female 1/28/2012 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 10/1/2010 -1 Female 314 lb 1/28/2012 Physician United States
Primary
Concomitant
Pain In Extremity 11/1/2011 63 Female 1/29/2012 Consumer United States
Primary
Concomitant
Fatigue 1/1/2010 Female 1/28/2012 Other Health Professional United States
Primary
Concomitant
Oral Disorder 8/1/2011 56 Female 1/28/2012 Consumer United States
Primary
Concomitant
Nephrolithiasis Other Serious 1/1/2011 60 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema Female 1/28/2012 Consumer United States
Primary
Concomitant
Anaemia 34 Female 2/10/2012 Consumer United States
Primary
Secondary
Concomitant
Constipation Other Serious 6/1/2011 85 Female 132 lb 2/24/2012 Physician United States
Primary
Concomitant
Cough Hospitalization 2/1/2011 76 Female 166 lb 3/21/2012 Consumer United States
Primary
Concomitant
Bowel Movement Irregularity 4/1/2012 Female 6/5/2012 Consumer United States
Primary
Concomitant
Spinal Fracture Hospitalization 2/1/2011 76 Female 166 lb 12/10/2012 Physician Us
Primary
Concomitant
Mouth Ulceration 6/13/2011 75 Female 162 lb 10/24/2012 Physician Us
Primary
Concomitant

Drug Data