Methotrexate combined with Vitamin C

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Breast Mass Hospitalization 12/18/2009 Female 156 lb 12/30/2009 Physician Argentina
Primary
Secondary
Concomitant
Breast Mass Hospitalization 12/18/2009 Female 156 lb 1/8/2010 Physician Argentina
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 11/2/2009 69 Female 158 lb 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Breast Mass Other Serious 10/14/2009 Female 156 lb 1/22/2010 Physician Argentina
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 Female 150 lb 1/25/2010 Physician Argentina
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/13/2005 Female 146 lb 1/28/2010 Physician United States
Primary
Concomitant
Intervertebral Disc Degeneration Hospitalization 11/2/2009 69 Female 158 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 Female 212 lb 1/28/2010 Consumer United States
Primary
Concomitant
Faeces Discoloured 5/4/2009 Female 206 lb 1/29/2010 United States
Primary
Concomitant
Skin Laceration 1/1/2009 Female 150 lb 1/30/2010 Consumer United States
Primary
Concomitant
Vaginal Cancer Other Serious 8/26/2009 Female 234 lb 1/30/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2009 Female 123 lb 1/30/2010 Other Health Professional United States
Primary
Concomitant
Rhinorrhoea 11/22/2009 Male 175 lb 1/30/2010 United States
Primary
Concomitant
Injection Site Pain 1/1/2007 Female 160 lb 1/30/2010 Consumer United States
Primary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 Female 150 lb 1/31/2010 Physician Argentina
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 11/11/2009 65 Female 1/25/2010 Physician Canada
Primary
Concomitant
Pneumonia Other Serious Female 132 lb 2/4/2010 Physician United States
Primary
Concomitant
Vaginal Prolapse Hospitalization 1/1/2009 Female 150 lb 2/8/2010 Canada
Primary
Concomitant
Vaginal Prolapse Hospitalization 1/1/2009 Female 150 lb 2/9/2010 Canada
Primary
Concomitant
Visual Impairment Other Serious 1/1/2008 Female 2/10/2010 United States
Primary
Concomitant
Breast Mass Other Serious 10/14/2009 Female 156 lb 2/12/2010 Physician Argentina
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 10/20/2008 56 Female 2/22/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 51 Female 192 lb 2/22/2010 Consumer United States
Primary
Concomitant
Vaginal Lesion Disability 11/23/2008 61 Female 2/25/2010 Physician United States
Primary
Concomitant
Nausea 9/15/2008 62 Female 134 lb 2/25/2010 Other Health Professional United States
Primary
Concomitant
Tuberculosis Test Positive Other Serious 1/27/2010 Female 2/26/2010 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 12/29/2007 Female 209 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 11/9/2009 Female 121 lb 2/10/2010 United States
Primary
Concomitant
Acute Respiratory Failure Hospitalization 65 Male 223 lb 3/11/2010 Consumer United States
Primary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 Female 150 lb 3/14/2010 Physician Argentina
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 10/1/2009 Female 3/15/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/29/2007 Female 209 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Breast Cancer Other Serious 10/14/2009 53 Female 156 lb 4/1/2010 Physician Argentina
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 1/1/2003 39 Female 130 lb 4/5/2010 Physician United States
Primary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 44 Female 150 lb 4/5/2010 Physician Argentina
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 11/2/2009 69 Female 158 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/29/2007 73 Female 209 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Splenic Rupture Hospitalization 8/21/2009 64 Female 134 lb 4/9/2010 Physician United States
Primary
Concomitant
Urinary Tract Neoplasm Other Serious 11/9/2009 65 Female 158 lb 4/16/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/29/2007 73 Female 209 lb 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/29/2007 73 Female 209 lb 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/29/2007 73 Female 209 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/29/2007 73 Female 209 lb 4/30/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/1/2010 66 Female 4/30/2010 Consumer United States
Primary
Concomitant
Breast Cancer Other Serious 10/14/2009 53 Female 156 lb 5/7/2010 Physician Argentina
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/9/2009 61 Female 116 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/9/2009 61 Female 116 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Skin Burning Sensation 3/5/2010 70 Male 190 lb 5/17/2010 Physician
Primary
Concomitant
Breast Cancer Other Serious 10/14/2009 53 Female 156 lb 5/18/2010 Physician Argentina
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/29/2007 73 Female 209 lb 5/18/2010 Physician United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 5/12/2010 49 Male 236 lb 5/21/2010 Physician Australia
Primary
Secondary
Concomitant
Macular Hole Other Serious 3/1/2010 62 Female 123 lb 5/28/2010 Consumer United States
Primary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 44 Female 150 lb 6/1/2010 Physician Argentina
Primary
Secondary
Concomitant
Lobar Pneumonia Other Serious 2/1/2010 45 Female 161 lb 6/2/2010 Canada
Primary
Concomitant
Wrist Deformity Other Serious 1/22/2010 78 Female 143 lb 6/10/2010 Physician United States
Primary
Concomitant
Localised Infection Hospitalization 5/28/2010 78 Male 6/11/2010 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 11/1/2009 74 Female 6/17/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 6/9/2010 64 Female 132 lb 6/17/2010 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 6/9/2010 64 Female 132 lb 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Traumatic Brain Injury Hospitalization 12/3/2009 27 Female 331 lb 6/24/2010 Physician Germany
Primary
Concomitant
Sjogren's Syndrome Other Serious Female 6/25/2010 Consumer United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 11/2/2009 69 Female 158 lb 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 44 Female 150 lb 6/29/2010 Physician Argentina
Primary
Secondary
Concomitant
Skin Infection Other Serious 2/18/2005 63 Female 7/2/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/1/2009 59 Female 7/8/2010 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iiib Other Serious Female 132 lb 7/9/2010 Physician United States
Primary
Concomitant
Localised Infection Hospitalization 5/28/2010 78 Male 7/13/2010 Consumer United States
Primary
Concomitant
Rash 6/1/2007 61 Female 126 lb 7/14/2010 Other Health Professional United States
Primary
Concomitant
Skin Infection Other Serious 2/18/2005 63 Female 7/16/2010 Physician United States
Primary
Concomitant
Constipation 1/1/2008 83 Female 90 lb 7/19/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 2/1/2010 66 Female 7/16/2010 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 4/18/2008 66 Male 188 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 7/2/2008 59 Female 165 lb 7/22/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2009 60 Female 174 lb 7/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Insomnia 68 Female 7/23/2010 Consumer Canada
Primary
Concomitant
Sinusitis Hospitalization 1/1/2008 63 Female 5/6/2011 Consumer United States
Primary
Concomitant
Musculoskeletal Pain Hospitalization 1/1/2010 66 Female 5/6/2011 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 3/31/2011 62 Female 5/10/2011 Consumer Canada
Primary
Concomitant
Fatigue Hospitalization 9/9/2010 82 Female 5/13/2011 Consumer Canada
Primary
Concomitant
Hypercapnia Life Threatening 6/16/2008 71 Male 230 lb 12/5/2011 Lawyer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 9/23/2011 64 Female 182 lb 12/21/2011 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 9/23/2011 64 Female 182 lb 12/23/2011 Physician United States
Primary
Concomitant
Wound Secretion Other Serious 12/1/2010 60 Female 183 lb 12/28/2011 Consumer United States
Primary
Concomitant
Syncope Other Serious 11/17/2011 64 Female 209 lb 1/3/2012 Other Health Professional Canada
Primary
Concomitant
Injury Hospitalization Female 203 lb 12/28/2011 Consumer United States
Primary
Concomitant
Bacterial Infection Hospitalization 10/18/2011 64 Male 150 lb 1/4/2012 Physician Canada
Primary
Concomitant
Muscle Spasms Hospitalization 12/1/2011 59 Male 1/5/2012 Consumer Canada
Primary
Concomitant
Rash 12/1/2010 79 Female 1/5/2012 Consumer United States
Primary
Concomitant
Colorectal Cancer Metastatic Life Threatening 11/8/2011 79 Female 187 lb 1/6/2012 Physician Netherlands
Primary
Secondary
Concomitant
Fall Disability 5/24/2011 84 Male 183 lb 1/10/2012 Physician United States
Primary
Concomitant
Headache Hospitalization 12/1/2011 59 Male 1/11/2012 Consumer Canada
Primary
Concomitant
Stress Other Serious 12/27/2011 66 Male 179 lb 1/11/2012 Consumer United States
Primary
Secondary
Concomitant
Sinusitis 11/1/2011 63 Female 1/11/2012 Consumer United States
Primary
Concomitant
Sinusitis 11/1/2011 63 Female 1/11/2012 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 1/1/2008 60 Female 123 lb 1/13/2012 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 1/1/2008 60 Female 123 lb 1/16/2012 Consumer United States
Primary
Concomitant
Fatigue Other Serious 12/1/2011 33 Female 1/17/2012 Consumer Canada
Primary
Concomitant
Neuropathy Peripheral Hospitalization 1/1/2011 75 Male 230 lb 1/18/2012 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased 1/1/2010 58 Female 115 lb 5/1/2012 Consumer United States
Primary
Concomitant
Hypertonic Bladder Other Serious 1/1/2005 55 Female 202 lb 5/3/2012 Consumer United States
Primary
Secondary
Concomitant
Walking Aid User Hospitalization 2/14/2010 60 Female 5/3/2012 Consumer United States
Primary
Concomitant
Pulmonary Congestion Other Serious 4/9/2012 65 Female 180 lb 5/25/2012 Consumer United States
Primary
Concomitant
Thyroid Neoplasm Hospitalization 1/1/2005 55 Female 202 lb 5/29/2012 Physician United States
Primary
Secondary
Concomitant
Scar Other Serious 5/16/2012 60 Male 243 lb 6/1/2012 Other Health Professional Canada
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2011 61 Female 220 lb 6/1/2012 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 4/2010 Female 205 lb 1/28/2013 Physician Country Not Specified
Primary
Concomitant
Cerebral Haemorrhage Death 5/24/2011 85 Male 183 lb 2/22/2013 Physician Us
Primary
Concomitant
Bacterial Infection Hospitalization 10/14/2011 64 Male 150 lb 10/30/2012 Physician Ca
Primary
Concomitant
Injection Site Swelling 9/2011 Female 125 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Iritis Other Serious 1/21/2012 43 Female 120 lb 2/19/2013 Other Health Professional Ca
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 8/2011 Female 140 lb 12/13/2012 Physician Ca
Primary
Concomitant
Synovial Cyst Other Serious 56 Female 9/20/2012 Physician Us
Primary
Concomitant
Walking Aid User Hospitalization 2002 Male 211 lb 10/24/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Ulcer Haemorrhage Other Serious 2012 Female 9/10/2012 Consumer Us
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2004 270 lb 9/15/2012 Consumer Country Not Specified
Primary
Concomitant
Wound Hospitalization 10/23/2011 60 Female 198 lb 10/19/2012 Physician Ca
Primary
Concomitant
Fungal Infection 8/2012 Female 172 lb 9/4/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Sepsis Disability 11/14/2011 66 Female 364 lb 10/23/2012 Consumer Us
Primary
Concomitant
Ulcer Haemorrhage Other Serious 2012 70 Female 9/11/2012 Consumer Us
Primary
Secondary
Concomitant
Urosepsis Hospitalization 6/2010 Female 190 lb 11/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Death 8/2012 Male 10/2/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Injection Site Swelling Female 214 lb 10/24/2012 Physician Us
Primary
Concomitant
Bronchitis 11/16/2011 55 170 lb 10/24/2012 Other Health Professional Us
Primary
Concomitant
Bronchitis 12/5/2011 64 Female 180 lb 10/24/2012 Other Health Professional Us
Primary
Concomitant
Rebound Psoriasis Hospitalization Male 380 lb 10/23/2012 Consumer Us
Primary
Concomitant
Urinary Retention Other Serious 61 Male 10/29/2012 Consumer Country Not Specified
Primary
Concomitant
Wound Haemorrhage Hospitalization 11/2011 Female 104 lb 12/26/2012 Consumer Us
Primary
Concomitant
Nasopharyngitis 10/25/2010 60 Male 11/7/2012 Physician Us
Primary
Concomitant
Vomiting Other Serious 10/2010 73 Female 214 lb 2/8/2013 Physician Us
Primary
Concomitant
Sinusitis 10/31/2011 48 Female 11/7/2012 Other Health Professional Us
Primary
Concomitant
Skin Discolouration 8/28/2011 51 Female 11/7/2012 Other Health Professional Us
Primary
Concomitant
Varicose Vein Other Serious 2005 Female 12/13/2012 Physician Country Not Specified
Primary
Concomitant
Carotid Artery Occlusion Hospitalization 9/16/2012 62 Female 150 lb 1/30/2013 Physician Us
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 12/19/2012 Consumer Us
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 11/2012 60 Male 210 lb 12/21/2012 Consumer Us
Primary
Concomitant
Local Swelling Other Serious 66 Female 1/11/2013 Consumer Country Not Specified
Primary
Concomitant
Cardiovascular Disorder Death 10/23/2012 66 Male 1/11/2013 Physician Country Not Specified
Primary
Concomitant
Pruritus Generalised Other Serious 12/19/2012 60 Female 146 lb 3/18/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Rheumatoid Arthritis 12/23/2011 53 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Pain 2009 53 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Psoriasis 12/26/2011 59 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Rash Pruritic 2/26/2012 54 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Upper-airway Cough Syndrome 1/2012 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Hot Flush 4/12/2012 13 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Unevaluable Event 2/22/2012 56 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Pain In Extremity 12/22/2011 54 Male 1/29/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Off Label Use Other Serious 1/18/2013 90 Male 139 lb 1/29/2013 Consumer Us
Primary
Concomitant
Prostatitis Other Serious 2/2012 Male 264 lb 1/29/2013 Physician Us
Primary
Concomitant
Treatment Noncompliance 12/29/2011 66 Male 180 lb 1/29/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Urinary Tract Infection 4/29/2012 30 Female 1/29/2013 Physician Country Not Specified
Primary
Concomitant

Drug Data