Methotrexate combined with Vitamin E

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Tract Infection Bacterial Other Serious 9/19/1999 69 Female 110 lb 1/4/2006 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 11/17/2005 Female 175 lb 1/5/2006 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 2/1/2005 Male 2/3/2006 Physician United States
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 5/1/2005 Female 119 lb 2/7/2006 Physician United States
Primary
Concomitant
Torsade De Pointes Life Threatening 3/31/2005 81 Female 153 lb 2/6/2006 Pharmacist United States
Primary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 7/1/2004 Female 2/24/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 2/5/2005 Male 3/1/2006 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 12/11/2005 Male 205 lb 3/1/2006 Physician United States
Primary
Concomitant
Gastroenteritis Hospitalization 8/24/2005 Female 3/1/2006 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 2/9/2006 62 Female 155 lb 3/20/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 6/21/2005 53 Female 3/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 2/9/2006 Female 161 lb 4/13/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 12/1/2005 Female 4/24/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 4/10/2006 62 Female 4/24/2006 Other Health Professional United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 2/9/2006 Female 161 lb 5/11/2006 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 3/10/2003 44 Male 238 lb 5/12/2006 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 8/1/2005 Female 5/12/2006 Physician United States
Primary
Concomitant
Gastroenteritis Hospitalization 4/10/2006 62 Female 5/16/2006 Other Health Professional United States
Primary
Concomitant
Calculus Bladder Hospitalization 3/1/2004 Male 177 lb 6/9/2006 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 10/1/2003 Female 294 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 5/17/2006 63 Female 6/22/2006 Physician United States
Primary
Concomitant
Vasculitic Rash Other Serious 12/18/2001 Female 118 lb 6/28/2006 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 12/1/2005 Male 7/10/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/1/2005 76 Female 7/13/2006 Consumer United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Male 215 lb 7/31/2006 Physician United States
Primary
Concomitant
Prothrombin Time Ratio Increased 1/1/2005 57 Female 201 lb 8/1/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2004 Female 8/16/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2004 Female 9/6/2006 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 12/19/2005 Male 9/6/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/29/2003 60 Female 9/5/2006 United States
Primary
Secondary
Concomitant
Sepsis Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/17/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Death Other Serious Female 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/5/2006 63 Female 150 lb 9/22/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 12/1/2005 Female 10/3/2006 Physician United States
Primary
Concomitant
Pyrexia Other Serious 8/5/2006 63 Female 150 lb 11/9/2006 Physician Japan
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 8/5/2006 63 Female 150 lb 11/15/2006 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 10/10/2006 56 Female 12/4/2006 Other Health Professional Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 5/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Breast Cancer Hospitalization 5/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 10/10/2006 56 Female 12/12/2006 Other Health Professional Canada
Primary
Concomitant
Tonsil Cancer Other Serious 1/1/2006 Female 182 lb 12/13/2006 Physician United States
Primary
Concomitant
Pruritus Generalised 3/22/2006 Female 12/14/2006 Consumer United States
Primary
Concomitant
Lower Respiratory Tract Infection 9/6/2006 75 Female 170 lb 12/22/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 7/25/2006 77 Female 122 lb 12/22/2006 Pharmacist United States
Primary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Oligodendroglioma Hospitalization 3/18/2005 66 Female 181 lb 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Menorrhagia Other Serious Female 2/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Hospitalization Female 3/1/2007 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Temporal Lobe Epilepsy Hospitalization 8/30/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 12/5/2006 Female 4/5/2007 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Female 207 lb 6/25/2007 Consumer United States
Primary
Concomitant
Spinal Fracture Other Serious 2/1/2007 Female 121 lb 6/25/2007 Physician United States
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 6/25/2007 United States
Primary
Concomitant
Breast Cancer Other Serious 6/21/2005 Female 6/26/2007 Physician United States
Primary
Secondary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 7/6/2007 United States
Primary
Concomitant
Vomiting Other Serious 3/31/2007 Female 7/13/2007 Other Health Professional Canada
Primary
Concomitant
Rheumatoid Lung Hospitalization 8/1/2007 82 Female 154 lb 10/4/2007 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 76 Female 10/4/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/4/2000 48 Female 154 lb 11/1/2007 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/1/2005 Female 152 lb 11/27/2007 Physician United States
Primary
Concomitant
Follicle Centre Lymphoma, Follicular Grade I, Ii, Iii Other Serious 8/1/2006 Female 12/6/2007 Physician United States
Primary
Concomitant
Injection Site Reaction Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/6/2006 Male 12/6/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 3/25/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/7/2007 Female 155 lb 12/14/2007 United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 12/18/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 5/4/2000 48 Female 154 lb 12/20/2007 Other Health Professional United States
Primary
Concomitant
Sinus Disorder 1/1/2006 57 Female 214 lb 12/21/2007 Consumer United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 12/27/2007 Physician United States
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 1/4/2008 United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 351 lb 1/21/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 5/4/2000 48 Female 154 lb 1/24/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 5/4/2000 48 Female 154 lb 2/4/2008 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2007 66 Female 202 lb 2/5/2008 Physician United States
Primary
Secondary
Tooth Extraction Other Serious 12/1/2000 74 Female 2/12/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 5/4/2000 48 Female 154 lb 2/18/2008 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2007 66 Female 202 lb 2/20/2008 Physician United States
Primary
Secondary
Nephrolithiasis Other Serious 1/1/2007 61 Female 351 lb 2/21/2008 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2007 66 Female 202 lb 2/27/2008 Physician United States
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 4/1/2005 Female 152 lb 2/28/2008 Physician United States
Primary
Concomitant
Injection Site Irritation 2/11/2008 Female 185 lb 3/15/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 5/4/2000 48 Female 154 lb 3/21/2008 Other Health Professional United States
Primary
Concomitant
Raynaud's Phenomenon 2/1/2006 54 Female 4/3/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased 4/15/2008 Female 240 lb 6/11/2008 United States
Primary
Concomitant
Haematoma 5/29/2008 59 Female 6/12/2008 Consumer Puerto Rico
Primary
Concomitant
Sciatica Female 157 lb 6/12/2008 United States
Primary
Concomitant
Localised Infection Other Serious 1/1/2004 Female 128 lb 6/16/2008 Consumer United States
Primary
Concomitant
Paranasal Sinus Hypersecretion 1/1/2007 57 Female 214 lb 6/30/2008 Physician United States
Primary
Concomitant
Pyrexia 1/1/2008 65 Female 185 lb 6/30/2008 Consumer United States
Primary
Concomitant
Osteomyelitis Other Serious 1/1/2004 Female 128 lb 7/2/2008 Physician United States
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 7/9/2008 United States
Primary
Concomitant
Prostate Cancer Other Serious 5/12/2008 Male 182 lb 7/7/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 5/4/2000 48 Female 154 lb 7/24/2008 Other Health Professional United States
Primary
Concomitant
Post Herpetic Neuralgia Hospitalization 8/2/2008 57 Female 137 lb 8/4/2008 Other Health Professional United States
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 9/11/2008 United States
Primary
Concomitant
White Blood Cell Count Increased 4/1/2008 Female 236 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Erythema Other Serious 12/16/1998 78 Female 138 lb 9/22/2008 Physician United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease 9/15/2008 Female 10 lb 9/19/2008 United States
Primary
Secondary
Concomitant
Weight Decreased 11/1/2007 63 Female 154 lb 9/25/2008 Consumer United States
Primary
Concomitant
Respiratory Distress Hospitalization 9/15/2008 Female 10 lb 9/30/2008 United States
Primary
Secondary
Concomitant
Synovitis Other Serious 2/11/2006 Female 198 lb 10/23/2008 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 9/14/2008 60 Female 10/27/2008 Consumer Canada
Primary
Concomitant
Treatment Noncompliance 6/13/2005 65 Female 1/31/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 3/13/2005 Female 146 lb 11/24/2008 Physician United States
Primary
Concomitant
Erythema Nodosum Female 122 lb 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Osteolysis Hospitalization 2/9/2007 Male 160 lb 12/26/2008 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/26/2004 80 Female 168 lb 2/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/17/2007 Female 2/25/2009 Consumer United States
Primary
Concomitant
Injection Site Pruritus 1/1/2005 Female 104 lb 3/14/2009 United States
Primary
Concomitant
Arthralgia 11/29/2008 Female 98 lb 3/14/2009 United States
Primary
Concomitant
Breast Cancer Other Serious 11/7/2008 53 Female 176 lb 3/20/2009 Physician Germany
Primary
Concomitant
Necrotising Fasciitis Hospitalization 12/15/2008 Female 146 lb 4/3/2009 United States
Primary
Concomitant
Necrotising Fasciitis Hospitalization 12/15/2008 Female 146 lb 4/16/2009 United States
Primary
Concomitant
Tendonitis 1/1/2008 76 Female 140 lb 4/30/2009 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2009 Male 5/28/2009 Physician United States
Primary
Concomitant
Paraesthesia 9/1/2008 Female 175 lb 6/11/2009 United States
Primary
Concomitant
Pyrexia Other Serious 6/1/2008 Female 155 lb 9/18/2009 Canada
Primary
Concomitant
Wheezing Other Serious 1/1/2006 Female 129 lb 11/5/2009 Physician United States
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2002 Male 233 lb 11/9/2009 Physician United States
Primary
Concomitant
Nasopharyngitis Other Serious 1/1/2009 Female 140 lb 11/20/2009 Brazil
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 129 lb 11/23/2009 Physician United States
Primary
Concomitant
Osteopenia 6/1/2008 Female 12/3/2009 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 5/12/2008 Male 182 lb 12/1/2009 Consumer United States
Primary
Concomitant
Pain In Extremity 1/1/2009 Female 188 lb 12/7/2009 Physician United States
Primary
Concomitant
Chromaturia 7/14/2009 Female 12/9/2009 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2002 Male 233 lb 12/17/2009 Physician United States
Primary
Concomitant
Necrotising Fasciitis Hospitalization 12/15/2008 Female 146 lb 12/23/2009 United States
Primary
Concomitant
Colonic Stenosis Hospitalization 1/8/2010 Female 1/21/2010 United States
Primary
Concomitant
Nasopharyngitis Other Serious 1/1/2009 Female 140 lb 1/28/2010 Brazil
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/13/2005 Female 146 lb 1/28/2010 Physician United States
Primary
Concomitant
Skin Disorder Hospitalization 1/1/2009 Female 170 lb 1/29/2010 Physician
Primary
Concomitant
Pain In Jaw 8/19/2009 Male 235 lb 1/29/2010 Consumer United States
Primary
Concomitant
Sinusitis 8/1/2009 Male 155 lb 1/30/2010 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection 11/27/2009 Female 135 lb 1/30/2010 United States
Primary
Concomitant
Aortic Aneurysm Hospitalization Female 200 lb 2/4/2010 Physician United States
Primary
Concomitant
Dyspepsia 6/1/2009 71 Female 203 lb 2/22/2010 Consumer United States
Primary
Concomitant
Aortic Aneurysm Hospitalization 9/18/2009 Female 200 lb 2/24/2010 Physician United States
Primary
Concomitant
Vaginal Lesion Disability 11/23/2008 61 Female 2/25/2010 Physician United States
Primary
Concomitant
Retinal Tear Other Serious 4/1/2009 Female 2/25/2010 Physician United States
Primary
Concomitant
Colon Cancer Hospitalization 10/29/2009 Female 3/19/2010 United States
Primary
Concomitant
Ocular Hyperaemia 66 Female 4/6/2010 Consumer United States
Primary
Concomitant
Bone Disorder Other Serious 1/1/2006 61 Female 129 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Disability 6/1/2007 70 Female 219 lb 4/15/2010 United States
Primary
Concomitant
Colon Cancer Hospitalization 10/29/2009 80 Female 5/4/2010 United States
Primary
Concomitant
Bone Disorder Other Serious 1/1/2006 61 Female 129 lb 5/18/2010 Other Health Professional United States
Primary
Concomitant
Rheumatoid Factor Increased Hospitalization 5/1/2010 64 Female 210 lb 7/16/2010 Consumer United States
Primary
Concomitant

Drug Data