Lovastatin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Breast Cancer Other Serious 11/17/2005 Female 175 lb 1/5/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 61 Male 170 lb 2/27/2006 Physician United States
Primary
Concomitant
Sudden Death Death 3/21/2006 80 Female 4/7/2006 Physician United States
Primary
Concomitant
Sudden Death Other Serious 3/21/2006 80 Female 4/20/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/11/2006 Male 5/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 2/28/2006 68 Female 6/6/2006 Physician United States
Primary
Concomitant
Lung Neoplasm Other Serious 6/12/2006 58 Male 6/14/2006 Consumer United States
Primary
Concomitant
Sudden Death Other Serious 3/21/2006 80 Female 6/8/2006 Physician United States
Primary
Concomitant
Weight Decreased 7/1/2005 57 Female 156 lb 4/17/2006 Consumer United States
Primary
Concomitant
Palpitations 4/4/2006 6/29/2006 Pharmacist United States
Primary
Concomitant
Erectile Dysfunction 4/14/2006 Male 6/28/2006 United States
Primary
Concomitant
Sudden Death Other Serious 7/1/2006 67 Female 10/9/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2006 Female 160 lb 11/16/2006 Consumer United States
Primary
Concomitant
Headache 1/1/2006 58 Female 258 lb 12/22/2006 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 6/29/2006 57 Female 11/28/2006 Pharmacist United States
Primary
Concomitant
Weight Increased 11/1/2006 63 Female 118 lb 2/14/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/13/2007 Female 161 lb 4/18/2007 Physician United States
Primary
Concomitant
Feeling Hot 72 Female 119 lb 9/20/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/14/2007 Consumer United States
Primary
Concomitant
Foreign Body Trauma Other Serious 1/1/2007 Female 12/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Temperature Intolerance 6/1/2007 Female 271 lb 12/14/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/1/2007 Female 227 lb 12/14/2007 Consumer United States
Primary
Concomitant
Contusion 10/4/2007 Male 229 lb 12/14/2007 United States
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2003 57 Female 11/28/2007 United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 12/1/2007 Female 1/4/2008 United States
Primary
Concomitant
Urinary Tract Inflammation Required Intervention 8/21/2007 69 Female 168 lb 1/12/2008 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 10/1/2007 65 Female 2/6/2008 Physician Canada
Primary
Concomitant
Osteoarthritis Other Serious 12/1/2007 Female 2/6/2008 Physician United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 12/1/2007 Male 2/18/2008 Physician United States
Primary
Concomitant
Aortic Aneurysm Rupture Other Serious 12/29/2007 Female 2/28/2008 Physician United States
Primary
Concomitant
Drug Ineffective 10/1/2007 Female 165 lb 3/14/2008 United States
Primary
Concomitant
Injection Site Pruritus 12/29/2007 Female 200 lb 3/15/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 2/21/2008 Female 195 lb 3/15/2008 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 2/23/2008 59 Male 260 lb 3/24/2008 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2007 Female 4/25/2008 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/1/2007 Female 5/6/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome 9/21/2007 5/13/2008 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 10/1/2007 65 Female 6/2/2008 Physician Canada
Primary
Concomitant
Staphylococcal Abscess Hospitalization 2/23/2008 59 Male 260 lb 5/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 9/1/2007 Female 170 lb 6/12/2008 United States
Primary
Concomitant
Accidental Exposure 3/26/2008 Male 162 lb 6/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 3/12/2008 Female 145 lb 6/13/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 6/1/2005 61 Female 222 lb 4/10/2008 Consumer United States
Primary
Concomitant
Viral Infection Life Threatening 6/1/2008 Female 145 lb 6/18/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Female 5/14/2008 Consumer United States
Primary
Concomitant
Wound Complication Hospitalization 2/12/2008 59 Male 260 lb 9/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 8/1/2007 Female 11/14/2008 United States
Primary
Concomitant
Chest Pain Hospitalization 11/12/2008 60 Female 11/26/2008 Consumer Colombia
Primary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 Female 138 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 11/12/2008 60 Female 12/2/2008 Consumer Colombia
Primary
Concomitant
Rheumatoid Arthritis 1/1/2003 Female 254 lb 12/13/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 1/8/2009 Physician United States
Primary
Concomitant
Tinnitus Other Serious 12/10/2008 Female 147 lb 1/14/2009 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 10/22/2008 Male 187 lb 1/16/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 1/23/2009 Physician United States
Primary
Concomitant
Procedural Complication 12/11/2008 Female 135 lb 3/14/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 4/30/2009 Physician United States
Primary
Concomitant
Staphylococcal Abscess Hospitalization 2/12/2008 59 Male 260 lb 5/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skull Fracture Other Serious 1/1/2009 Male 212 lb 5/21/2009 United States
Primary
Concomitant
Pain 2/1/2009 Female 218 lb 6/11/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2004 75 Female 7/2/2009
Primary
Secondary
Concomitant
Skull Fracture Other Serious 1/1/2009 Male 212 lb 7/9/2009 United States
Primary
Concomitant
Incorrect Dose Administered 2/21/2008 Female 195 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation 3/26/2008 Male 162 lb 9/12/2009 Consumer United States
Primary
Concomitant
Skin Fissures 3/1/2009 Female 167 lb 9/18/2009 Consumer Puerto Rico
Primary
Concomitant
Radiculopathy 7/23/2009 Female 154 lb 9/19/2009 Physician United States
Primary
Concomitant
Sleep Disorder 7/18/2005 54 Female 236 lb 9/23/2009 United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/11/2009 Female 9/25/2009 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious Female 150 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/13/2009 41 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Bowen's Disease Other Serious Female 150 lb 11/30/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/30/2009 Consumer United States
Primary
Concomitant
Aortic Aneurysm Rupture Other Serious 12/29/2007 Female 11/30/2009 Physician United States
Primary
Concomitant
Cough Hospitalization 1/1/2009 50 Female 249 lb 12/8/2009 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization Female 151 lb 12/9/2009 Consumer
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2009 50 Female 249 lb 12/24/2009 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness 1/1/2009 Female 1/29/2010 Other Health Professional United States
Primary
Concomitant
Muscle Spasms Female 175 lb 1/30/2010 Consumer United States
Primary
Concomitant
Respiratory Tract Infection 12/1/2008 Male 155 lb 1/30/2010 United States
Primary
Concomitant
Injection Site Pain 11/18/2009 Male 235 lb 1/30/2010 Consumer United States
Primary
Concomitant
Wound Haemorrhage 12/15/2009 Female 200 lb 1/30/2010 United States
Primary
Concomitant
Mobility Decreased Female 250 lb 1/30/2010 United States
Primary
Concomitant
Aortic Aneurysm Hospitalization Female 200 lb 2/4/2010 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 3/1/2009 64 Male 209 lb 2/22/2010 Physician United States
Primary
Concomitant
Aortic Aneurysm Hospitalization 9/18/2009 Female 200 lb 2/24/2010 Physician United States
Primary
Concomitant
Diabetic Foot Hospitalization 1/5/2010 Female 148 lb 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 3/12/2010 Female 192 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 3/12/2010 Female 192 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 12/20/2009 71 Female 146 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 3/12/2010 73 Female 192 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/19/2010 60 Male 267 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/28/2008 67 Female 208 lb 4/12/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/11/2001 54 Female 4/15/2010 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/21/2010 60 Male 267 lb 4/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/11/2001 54 Female 4/21/2010 United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 10/22/2008 73 Male 187 lb 4/29/2010 United States
Primary
Concomitant
Renal Cyst Hospitalization 7/31/2008 70 Male 164 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 6/3/2010 Physician United States
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 5/24/2010 88 Female 6/9/2010 Consumer United States
Primary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 6/24/2010 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 8/11/2009 71 Female 184 lb 6/29/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/11/2001 54 Female 7/26/2010 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 51 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 7/4/2010 70 Female 140 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Flushing 10/1/2009 54 Male 195 lb 8/28/2010 United States
Primary
Concomitant
Paraesthesia Female 135 lb 8/28/2010 Consumer United States
Primary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 8/31/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 5/24/2010 88 Female 9/1/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2009 50 Female 249 lb 9/16/2010 Physician United States
Primary
Concomitant
Labile Hypertension Other Serious 1/1/2007 62 Female 250 lb 9/17/2010 Physician United States
Primary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 9/21/2010 Physician United States
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 5/24/2010 88 Female 9/30/2010 Consumer United States
Primary
Concomitant
Cerebral Infarction Other Serious 7/4/2010 70 Female 140 lb 10/1/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/11/2001 54 Female 10/4/2010 United States
Primary
Secondary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 10/6/2010 Physician United States
Primary
Concomitant
Stent Placement Other Serious 9/1/2010 55 Male 320 lb 10/8/2010 Other Health Professional United States
Primary
Concomitant
Confusional State Other Serious 8/1/2010 69 Male 186 lb 10/15/2010 Consumer United States
Primary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 10/21/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/11/2001 54 Female 10/29/2010 United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 9/1/2010 55 Male 320 lb 11/1/2010 Other Health Professional United States
Primary
Concomitant
Cerebral Infarction Other Serious 7/4/2010 70 Female 140 lb 11/9/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2010 53 Male 11/12/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2010 68 Male 12/10/2010 Physician United States
Primary
Concomitant
Skin Discolouration Hospitalization 10/20/2010 66 Female 12/7/2010 Consumer Colombia
Primary
Concomitant
Dizziness 11/29/2009 12/14/2010 Consumer United States
Primary
Concomitant
Influenza 12/16/2009 12/15/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2010 68 Male 12/17/2010 Physician United States
Primary
Concomitant
Rash Generalised 12/14/2009 12/17/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/20/2009 12/17/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Reaction 1/21/2010 12/17/2010 Consumer United States
Primary
Concomitant
Injection Site Reaction 12/19/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 11/29/2010 71 Female 126 lb 12/20/2010 Consumer United States
Primary
Concomitant
Skin Exfoliation 12/22/2010 Consumer United States
Primary
Concomitant
Injection Site Warmth 6/6/2010 12/22/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 6/28/2010 12/23/2010 Consumer United States
Primary
Concomitant
Tooth Fracture 8/1/2010 12/23/2010 Physician United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2008 68 Female 1/6/2011 Physician
Primary
Concomitant
Pneumonia Hospitalization 4/28/2008 67 Female 208 lb 1/10/2011 Physician United States
Primary
Concomitant
Joint Swelling Other Serious 11/29/2010 72 Female 126 lb 1/14/2011 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 10/20/2010 66 Female 1/28/2011 Consumer Colombia
Primary
Concomitant
Bronchitis Hospitalization Male 240 lb 1/28/2011 Consumer United States
Primary
Concomitant
Bronchitis 12/25/2009 50 Female 1/28/2011 Consumer United States
Primary
Concomitant
Generalised Erythema 2/17/2010 69 Male 240 lb 1/28/2011 Physician United States
Primary
Concomitant
Injection Site Pain Other Serious 1/1/2009 60 Female 170 lb 1/29/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage 6/25/2010 65 Female 1/29/2011 Consumer United States
Primary
Concomitant
Abnormal Behaviour 12/13/2010 48 Male 1/30/2011 Consumer United States
Primary
Concomitant

Drug Data