Humalog combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Palpitations Other Serious 11/18/2005 Female 1/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Postoperative Wound Infection Other Serious Female 210 lb 2/7/2006 Physician United States
Primary
Concomitant
Urinary Retention 57 Female 4/28/2006 Consumer United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 10/1/2003 Female 294 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 9/10/2005 42 Female 144 lb 7/28/2006 Pharmacist United States
Primary
Concomitant
Weight Loss Diet Hospitalization 1/1/2006 46 Female 248 lb 8/29/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 8/7/2006 48 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 9/15/2006 Female 130 lb 10/3/2006 Physician Sweden
Primary
Concomitant
Infection Hospitalization 9/15/2006 Female 130 lb 10/13/2006 Physician Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 50 Female 1/4/2007 Pharmacist Canada
Primary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Vomiting 9/5/2006 65 Female 195 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2004 72 Female 192 lb 11/27/2006 United States
Primary
Concomitant
Palpitations 61 Female 229 lb 3/27/2007 Consumer United States
Primary
Concomitant
Myalgia Hospitalization 10/1/2005 52 Male 182 lb 4/2/2007 Consumer United States
Primary
Concomitant
Wrong Drug Administered Other Serious 1/1/2000 65 Male 5/2/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 8/1/2006 Female 123 lb 6/25/2007 Consumer United States
Primary
Concomitant
Wrong Drug Administered Other Serious 1/1/2000 65 Male 5/9/2007 Consumer United States
Primary
Secondary
Concomitant
Femur Fracture Other Serious 6/26/2007 63 Female 200 lb 8/5/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/28/2007 51 Male 186 lb 8/22/2007 Physician United States
Primary
Concomitant
Somnolence 3/1/2007 Female 300 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/28/2007 51 Male 186 lb 9/7/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 8/4/2007 69 Male 284 lb 9/17/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2006 55 Female 175 lb 9/14/2007 Physician United States
Primary
Concomitant
Weight Decreased 8/1/2006 50 Female 123 lb 9/26/2007 Consumer United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 10/22/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 8/1/2007 Male 560 lb 11/20/2007 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 58 Female 132 lb 12/18/2007 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 71 Male 1/9/2008 Physician France
Primary
Secondary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 1/24/2008 Physician United States
Primary
Concomitant
Tooth Abscess Hospitalization 1/1/2002 57 Female 132 lb 2/28/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/27/2007 58 Male 3/28/2008 Physician France
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 6/27/2007 Female 326 lb 3/31/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Life Threatening 3/8/2008 48 Male 248 lb 3/28/2008 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 4/25/2008 60 Male 5/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/25/2008 60 Male 6/3/2008 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization Male 7/18/2008 Consumer United States
Primary
Concomitant
Pain 10/1/2007 69 Female 7/7/2008 Consumer United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 11/12/2007 Male 275 lb 9/22/2008 Physician United States
Primary
Concomitant
Toe Amputation Other Serious 1/1/2008 Male 174 lb 10/20/2008 Physician United States
Primary
Concomitant
Post Herpetic Neuralgia 4/14/2008 Female 12/11/2008 Physician United States
Primary
Concomitant
Synovitis Other Serious 10/1/2008 67 Male 203 lb 12/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Synovitis Other Serious 10/1/2008 67 Male 203 lb 12/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 5/1/2008 1/23/2009 France
Primary
Concomitant
Interacting
Weight Increased Other Serious 1/1/2006 Male 2/20/2009 Physician Canada
Primary
Concomitant
Sleep Disorder Other Serious 1/30/2009 Male 192 lb 4/24/2009 United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/29/2008 Male 265 lb 4/24/2009 Physician United States
Primary
Concomitant
Pain 3/1/2009 Female 196 lb 6/12/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 5/1/2009 Female 136 lb 6/12/2009 Consumer United States
Primary
Concomitant
Generalised Oedema Hospitalization 6/23/2009 Female 316 lb 7/21/2009 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/31/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2004 Female 220 lb 9/4/2009 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2004 Female 220 lb 9/9/2009 Consumer United States
Primary
Concomitant
Injection Site Haematoma 7/7/2009 Female 137 lb 9/19/2009 United States
Primary
Concomitant
Injection Site Pain 7/25/2009 Female 250 lb 9/19/2009 Consumer United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 1/1/2009 Female 251 lb 10/30/2009 Consumer United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 11/6/2009 Physician United States
Primary
Secondary
Concomitant
Tongue Injury Other Serious 10/13/2008 Female 11/30/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 12/1/2009 Physician Canada
Primary
Concomitant
Pneumonia Legionella Hospitalization 11/17/2009 51 Male 12/4/2009 Physician Italy
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 1/1/2009 51 Female 123 lb 2/2/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious Female 139 lb 3/1/2010 Consumer United Kingdom
Primary
Concomitant
Rheumatoid Nodule Hospitalization 1/1/2009 51 Female 123 lb 3/30/2010 Consumer United States
Primary
Concomitant
Mixed Hepatocellular Cholangiocarcinoma Life Threatening Male 5/10/2010 Other Health Professional Germany
Primary
Concomitant
Weight Decreased Other Serious Female 139 lb 5/10/2010 Consumer Brazil
Primary
Concomitant
Cellulitis Other Serious 44 Female 6/4/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/5/2010 63 Female 139 lb 7/16/2010 Consumer Brazil
Primary
Concomitant
Loss Of Consciousness Life Threatening 6/29/2010 47 Male 192 lb 7/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Death Hospitalization 7/10/2010 76 Male 7/21/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 5/1/2010 73 Female 158 lb 7/27/2010 Physician United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 7/2/2010 46 Female 180 lb 8/5/2010 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 4/13/2010 72 Female 185 lb 8/10/2010 Physician United States
Primary
Secondary
Concomitant
Flushing 1/1/2008 46 Female 350 lb 8/29/2010 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 4/13/2010 72 Female 185 lb 9/20/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2010 63 Female 10/26/2010 Consumer United States
Primary
Concomitant
Genital Haemorrhage Hospitalization 1/1/2007 63 Female 140 lb 1/11/2011 Consumer Canada
Primary
Concomitant
Epistaxis Other Serious 1/12/2011 1/19/2011 Consumer Netherlands
Primary
Concomitant
Anaemia Hospitalization 4/5/2010 63 Female 139 lb 1/25/2011 Consumer Brazil
Primary
Concomitant
Pain 8/26/2010 56 Male 1/29/2011 Consumer United States
Primary
Concomitant
Drug Administration Error 8/1/2009 62 Male 195 lb 1/29/2011 Physician United States
Primary
Concomitant
Vision Blurred 5/1/2010 76 Female 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 7/1/2010 57 Female 1/29/2011 Consumer United States
Primary
Concomitant
Otitis Media 10/1/2010 54 Female 175 lb 1/29/2011 Consumer Puerto Rico
Primary
Concomitant
Injection Site Erythema 9/3/2010 48 Female 1/29/2011 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/1/2010 52 Male 2/18/2011 Consumer France
Primary
Secondary
Concomitant
Respiratory Tract Infection Fungal Death 4/1/2008 44 Female 189 lb 2/21/2011 Lawyer United States
Primary
Concomitant
Death Death 3/3/2011 65 Female 3/24/2011 Other Health Professional Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 8/1/2010 52 Male 3/24/2011 Consumer France
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 11/1/2010 38 Female 3/30/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2011 59 Female 4/20/2011 Consumer United States
Primary
Concomitant
Hepatotoxicity Hospitalization 1/1/2009 71 Female 110 lb 4/21/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Myositis Hospitalization 1/1/2003 44 Female 189 lb 4/21/2011 Lawyer United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 6/10/2010 63 Female 132 lb 5/4/2011 Physician United Kingdom
Primary
Concomitant
Mycobacterium Tuberculosis Complex Test Positive Other Serious 1/1/2010 67 Female 125 lb 5/5/2011 Consumer United States
Primary
Concomitant
Herpes Zoster Other Serious 4/5/2010 63 Female 132 lb 6/21/2011 Consumer Brazil
Primary
Concomitant
Drug Ineffective Other Serious 3/3/2011 65 Female 148 lb 6/21/2011 Other Health Professional Canada
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 1/1/2009 71 Female 110 lb 7/7/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Endometriosis Other Serious 1/1/2010 36 Female 238 lb 7/14/2011 Other Health Professional Canada
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 12/1/2010 50 Male 8/11/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Injection Site Erythema Other Serious 1/1/2008 64 Female 8/30/2011 Consumer United States
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 12/1/2010 50 Male 9/2/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Injection Site Warmth Other Serious 1/1/2008 64 Female 9/7/2011 Consumer United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 7/19/2011 57 Female 112 lb 9/8/2011 Physician Japan
Primary
Secondary
Concomitant
Appendicitis Hospitalization 4/11/2011 43 Male 171 lb 9/12/2011 Physician United States
Primary
Secondary
Concomitant
Appendicitis Hospitalization 4/4/2011 43 Male 171 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 4/4/2011 43 Male 171 lb 9/26/2011 Physician United States
Primary
Secondary
Concomitant
Salivary Gland Cancer Death 3/1/2006 38 Female 9/27/2011 Physician Norway
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/4/2011 63 Male 250 lb 9/9/2011 Pharmacist United States
Primary
Secondary
Concomitant
Flatulence Hospitalization 67 Female 10/7/2011 Other Health Professional New Zealand
Primary
Concomitant
Interacting
Abdominal Discomfort Other Serious 1/8/2011 74 Female 110 lb 10/13/2011 Consumer Japan
Primary
Concomitant
Weight Increased Hospitalization 9/24/2011 55 Female 258 lb 10/12/2011 Consumer United States
Primary
Concomitant
Injection Site Reaction 6/8/2011 20 Female 106 lb 11/2/2011 Other Health Professional United States
Primary
Concomitant
Headache 8/1/2004 51 Male 240 lb 11/3/2011 Other Health Professional United States
Primary
Concomitant
Salivary Gland Cancer Death 3/1/2006 38 Female 11/10/2011 Physician Norway
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Other Serious 4/4/2011 43 Male 171 lb 11/18/2011 Physician United States
Primary
Secondary
Concomitant
Hypercapnia Life Threatening 6/16/2008 71 Male 230 lb 12/5/2011 Lawyer United States
Primary
Concomitant
Salivary Gland Cancer Death 3/1/2006 38 Female 12/19/2011 Physician Norway
Primary
Secondary
Concomitant
Cardiac Valve Disease Hospitalization 1/1/2011 72 Male 166 lb 12/21/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 10/13/2011 74 Female 134 lb 12/27/2011 Other Health Professional Canada
Primary
Concomitant
Dyspnoea Hospitalization Female 269 lb 12/21/2011 Physician United States
Primary
Concomitant
Herpes Zoster Life Threatening 10/26/2009 63 Female 132 lb 1/19/2012 Physician Brazil
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2011 77 Female 250 lb 1/23/2012 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 5/1/2011 67 Female 208 lb 1/28/2012 Consumer United States
Primary
Concomitant
Restlessness 12/1/2010 31 Female 200 lb 1/27/2012 Consumer United States
Primary
Concomitant
Toothache 1/1/2007 65 Male 1/27/2012 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 3/1/2011 71 Female 1/28/2012 Consumer United States
Primary
Secondary
Concomitant
Device Malfunction 67 Female 1/28/2012 Consumer United States
Primary
Concomitant
Diarrhoea 8/24/2011 46 Male 156 lb 1/28/2012 Consumer United States
Primary
Concomitant
Contusion 1/1/2010 66 Female 1/28/2012 Consumer United States
Primary
Concomitant
Arthralgia 1/1/2010 62 Female 160 lb 1/28/2012 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/10/2011 49 Female 2/1/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 4/10/2011 49 Female 2/3/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/10/2011 49 Female 2/3/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Salivary Gland Cancer Death 3/1/2006 39 Female 2/6/2012 Other Health Professional Norway
Primary
Secondary
Concomitant
Synovial Cyst Other Serious 1/1/2011 77 Female 250 lb 2/14/2012 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/10/2011 49 Female 3/9/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2011 43 Male 171 lb 3/29/2012 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/9/2012 69 Male 4/10/2012 Physician Norway
Primary
Concomitant
Oxygen Supplementation Other Serious Female 178 lb 4/12/2012 Consumer United States
Primary
Concomitant
Cystitis 3/28/2012 59 Female 176 lb 4/13/2012 Other Health Professional Canada
Primary
Concomitant
Vomiting 3/1/2010 62 Female 148 lb 5/2/2012 Physician United States
Primary
Concomitant
Ankle Fracture Other Serious Female 5/21/2012 Consumer United States
Primary
Concomitant

Drug Data