Methotrexate combined with Nexium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Basal Cell Carcinoma Other Serious 1/1/2005 Female 150 lb 1/3/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 8/28/2003 73 Female 258 lb 1/4/2006 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 9/1/2005 63 Female 1/5/2006 Consumer United States
Primary
Concomitant
Sciatica Hospitalization 9/1/2005 63 Female 1/17/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/4/2005 48 Female 1/17/2005 Australia
Primary
Secondary
Concomitant
Metastatic Malignant Melanoma Other Serious 1/1/2005 Female 161 lb 1/25/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 9/1/2005 Female 133 lb 2/1/2006 Other Health Professional United States
Primary
Concomitant
Spinal Fusion Surgery Other Serious 6/9/2003 Female 142 lb 2/10/2006 Physician United States
Primary
Secondary
Concomitant
Pleurisy Other Serious 12/1/2004 52 Female 2/17/2006 Consumer Australia
Primary
Concomitant
Upper Limb Fracture Hospitalization 2/1/2003 73 Female 110 lb 2/22/2006 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 11/1/2005 Female 167 lb 2/24/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 1/26/2005 Male 3/1/2006 Physician Norway
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2004 Male 3/1/2006 Physician Norway
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/8/2003 Male 3/1/2006 Other Health Professional Norway
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2005 Female 155 lb 3/1/2006 Consumer United States
Primary
Concomitant
Scotoma Other Serious 9/1/2005 Female 175 lb 3/8/2006 Physician United States
Primary
Concomitant
Oedema Other Serious 12/23/2005 68 Female 3/3/2006 Physician Finland
Primary
Concomitant
Tuberculosis Other Serious Female 156 lb 3/15/2006 Physician United States
Primary
Concomitant
Restless Legs Syndrome Hospitalization 11/2/2005 Female 170 lb 3/15/2006 Other Health Professional United States
Primary
Concomitant
Breast Cancer Life Threatening Female 176 lb 3/21/2006 Physician Netherlands
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 7/1/2005 Male 3/28/2006 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/11/2006 Male 3/28/2006 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 11/10/2005 40 Male 220 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Nausea 9/1/2005 47 Female 203 lb 1/20/2006 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 1/1/2000 78 Female 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/30/2003 77 Female 134 lb 4/11/2006 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/18/2005 68 Female 112 lb 11/4/2005 United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Female 4/14/2006 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 6/3/2002 70 Male 130 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 12/5/2000 73 Female 258 lb 4/25/2006 Physician United States
Primary
Concomitant
Respiratory Distress Hospitalization 1/1/2000 78 Female 150 lb 5/3/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 12/5/2000 73 Female 258 lb 5/5/2006 Physician United States
Primary
Concomitant
Yellow Skin Other Serious 4/1/1997 Female 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Increased Tendency To Bruise Other Serious 69 Male 154 lb 5/5/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/10/2006 Physician Australia
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 1/1/2006 73 Female 220 lb 5/16/2006 Physician Netherlands
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/16/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/17/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 8/8/2005 48 Female 5/19/2006 Physician Australia
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 5/23/2006 Other Health Professional France
Primary
Secondary
Renal Failure Life Threatening 2/1/2006 73 Female 220 lb 5/26/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 10/1/2005 Female 5/26/2006 Physician United States
Primary
Concomitant
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 5/26/2006 Physician France
Primary
Secondary
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 5/26/2006 Consumer France
Primary
Secondary
Yellow Skin Other Serious 4/1/1997 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Psoriasis Hospitalization 7/1/2005 Male 6/7/2006 Other Health Professional Finland
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/1/2005 Female 5/26/2006 Consumer United States
Primary
Concomitant
Pneumonitis Cryptococcal Other Serious 1/1/2006 Female 182 lb 6/8/2006 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 11/1/2005 Male 6/9/2006 Physician United States
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 5/1/2006 Female 215 lb 6/9/2006 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Death Female 6/12/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/1/2005 Female 5/30/2006 Consumer United States
Primary
Concomitant
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 6/20/2006 Other Health Professional France
Primary
Secondary
Peritonitis Life Threatening 5/1/2005 Female 143 lb 6/21/2006 Other Health Professional Canada
Primary
Concomitant
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 6/22/2006 Physician France
Primary
Secondary
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 6/22/2006 Consumer France
Primary
Secondary
Urticaria Other Serious 5/17/2006 63 Female 6/22/2006 Physician United States
Primary
Concomitant
Pneumonitis Cryptococcal Other Serious 4/1/2006 Female 182 lb 6/30/2006 Other Health Professional United States
Primary
Concomitant
Rash Maculo-papular Hospitalization 3/14/2006 57 Male 176 lb 7/7/2006 Physician France
Primary
Concomitant
Skin Cancer Other Serious 10/1/2005 Female 7/10/2006 Physician United States
Primary
Concomitant
B-cell Lymphoma Stage I Other Serious 8/4/2004 Female 128 lb 7/11/2006 Other Health Professional United States
Primary
Concomitant
Eye Inflammation Other Serious 3/1/2006 Female 6/15/2006 United States
Primary
Concomitant
Pustular Psoriasis Other Serious 3/14/2006 57 Male 187 lb 7/20/2006 Physician France
Primary
Concomitant
Stomach Granuloma Hospitalization 3/20/2006 23 Female 7/20/2006 Other Health Professional France
Primary
Concomitant
Interacting
Speech Disorder Other Serious 6/26/2006 74 Male 190 lb 7/20/2006 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 12/1/2005 76 Female 7/13/2006 Consumer United States
Primary
Concomitant
B-cell Lymphoma Stage I Other Serious 8/4/2004 Female 128 lb 8/1/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Streptococcal Other Serious 12/8/2005 36 Male 165 lb 8/3/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/1/2002 Male 180 lb 8/7/2006 Physician United States
Primary
Concomitant
Vaginal Cancer Other Serious 7/1/2006 Female 155 lb 8/7/2006 Other Health Professional United States
Primary
Concomitant
B-cell Small Lymphocytic Lymphoma Stage Iv Other Serious 12/10/2003 Female 142 lb 8/8/2006 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 4/20/2006 Female 148 lb 8/10/2006 Physician United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 4/1/2006 56 Female 193 lb 8/8/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/24/2003 43 Female 7/5/2006 United States
Primary
Concomitant
Hypoaesthesia Facial Other Serious 12/27/2004 66 Male 8/11/2006 Pharmacist United States
Primary
Concomitant
Throat Tightness Other Serious 1/1/2004 Male 270 lb 8/18/2006 Consumer United States
Primary
Concomitant
Sedation Other Serious 1/1/2005 Female 8/18/2006 Consumer
Primary
Concomitant
Tachycardia Other Serious 2/1/2006 Female 8/18/2006 Physician United States
Primary
Concomitant
Pneumonia Streptococcal Other Serious 12/8/2005 36 Male 165 lb 8/21/2006 Physician France
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 3/14/2006 57 Male 187 lb 8/24/2006 Physician France
Primary
Concomitant
Spinal Disorder Hospitalization Male 210 lb 8/30/2006 Consumer United States
Primary
Concomitant
Cystitis Hospitalization 7/1/2006 72 Female 250 lb 9/1/2006 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Death 9/12/2006 18 Female 9/15/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 8/1/2002 Male 180 lb 9/27/2006 Physician United States
Primary
Concomitant
Inflammatory Carcinoma Of The Breast Other Serious 8/14/2006 Female 9/27/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 8/7/2006 48 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Other Serious 8/29/2006 Female 149 lb Physician United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/9/2005 Male 164 lb 10/5/2006 Physician Australia
Primary
Concomitant
Throat Tightness Other Serious 1/1/2004 Male 270 lb 10/5/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2006 72 Female 250 lb 9/22/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Hospitalization Female 10/6/2006 Pharmacist Germany
Primary
Concomitant
Vaginal Cancer Other Serious 7/1/2006 Female 155 lb 10/9/2006 Other Health Professional United States
Primary
Concomitant
Oral Candidiasis Hospitalization 1/26/2006 Female 187 lb 10/9/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2004 Male 272 lb 10/9/2006 Physician United States
Primary
Concomitant
Sudden Death Other Serious 7/1/2006 67 Female 10/9/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2004 Male 272 lb 10/13/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Female 134 lb 10/16/2006 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Required Intervention 9/1/2006 18 Female 10/4/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 150 lb 10/16/2006 United States
Primary
Secondary
Concomitant
Endometrial Cancer Other Serious Female 276 lb 12/4/2006 Physician United States
Primary
Concomitant
Histoplasmosis Hospitalization 5/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Facial Palsy Disability 1/1/2006 60 Female 12/8/2006 Consumer United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 5/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious 2/1/2005 Female 12/13/2006 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 12/6/2005 Male 208 lb 12/13/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/16/2006 Female 152 lb 12/13/2006 Physician United States
Primary
Concomitant
Stress 11/9/2004 Female 158 lb 12/18/2006 Physician United States
Primary
Concomitant
Injection Site Pain 5/1/2006 Female 12/20/2006 Pharmacist United States
Primary
Concomitant
Malaise 2/9/2006 Female 12/21/2006 Other Health Professional United States
Primary
Concomitant
Paraesthesia 6/1/2006 Female 12/22/2006 Consumer United States
Primary
Concomitant
Rash Other Serious 39 Female 1/9/2007 Pharmacist Canada
Primary
Concomitant
Diarrhoea 7/16/2006 43 Female 135 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Neoplasm Malignant Other Serious 6/8/2006 Female 158 lb 1/16/2007 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious 2/1/2003 43 Male 11/28/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 2/9/2005 69 Female 130 lb 11/28/2006 Other Health Professional United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 8/1/2006 69 Male 226 lb 1/11/2007 Physician United States
Primary
Concomitant
Diverticulitis Death Female 1/25/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/26/2006 Female 171 lb 1/25/2007 Physician United States
Primary
Concomitant
Weight Decreased 8/31/2006 71 Female 230 lb 10/16/2006 Consumer United States
Primary
Concomitant
Spinal Column Stenosis Other Serious 11/1/2005 Female 183 lb 2/2/2007 Physician United States
Primary
Concomitant
Embolism Other Serious 1/25/2007 54 Male 164 lb 2/6/2007 Consumer United States
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 1/9/2006 Female 2/7/2007 Physician Norway
Primary
Secondary
Concomitant
Colon Cancer Other Serious 6/1/2006 Female 158 lb 2/9/2007 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 1/1/2006 Female 2/12/2007 Physician United States
Primary
Concomitant
Erythema Other Serious 12/1/2006 67 Female 2/12/2007 Physician Sweden
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/1/2005 Female 183 lb 2/14/2007 Physician United States
Primary
Secondary
Concomitant
Breast Neoplasm Other Serious 9/1/2006 72 Female 181 lb 2/15/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/12/2006 50 Male 166 lb 2/9/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/12/2006 51 Male 166 lb 2/20/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Skin Cancer Other Serious 2/1/2006 Female 170 lb 2/28/2007 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious 7/1/2006 Male 3/1/2007 Physician United States
Primary
Concomitant
Hypertension Other Serious 1/1/2006 Female 3/15/2007 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 7/1/2006 50 Female 170 lb 3/13/2007 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1/23/2003 47 Female 195 lb 12/8/2006 Other Health Professional United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 8/1/2006 69 Male 226 lb 3/13/2007 Physician United States
Primary
Concomitant
Large Granular Lymphocytosis Other Serious 10/1/2006 Male 3/27/2007 Physician United States
Primary
Concomitant
Hypersensitivity Life Threatening 12/13/2006 68 Female 3/27/2007 Consumer United States
Primary
Concomitant
Fatigue 12/22/2006 39 Female 146 lb 3/27/2007 Consumer United States
Primary
Concomitant
Sinusitis 24 Female 3/27/2007 Physician United States
Primary
Concomitant
Coronary Artery Occlusion Life Threatening 1/12/2007 72 Female 226 lb 3/21/2007 Other Health Professional United States
Primary
Concomitant
Meningitis Aseptic Other Serious 3/10/2007 59 Female 4/9/2007 Physician Switzerland
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 2/26/2007 Male 173 lb 4/11/2007 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 7/1/2006 Female 170 lb 4/18/2007 Consumer United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 1/1/2006 Female 196 lb 4/25/2007 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2006 Female 4/25/2007 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2006 46 Female 117 lb 4/30/2007 United States
Primary
Concomitant
Ovarian Cancer Other Serious 1/5/2004 69 Female 161 lb 5/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Heart Rate Irregular Other Serious 4/1/2007 Male 5/16/2007 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 12/1/2003 Female 5/18/2007 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 5/5/2007 Male 168 lb 5/22/2007 Physician Netherlands
Primary
Concomitant

Drug Data