Amitriptyline Hcl combined with Methotrexate

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Penis Carcinoma Other Serious 11/3/2005 Male 229 lb 1/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 12/25/2005 57 Male 235 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Arthritis Other Serious 10/15/2005 Female 176 lb 1/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious Female 1/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/7/2005 Male 229 lb 1/27/2006 Physician Brazil
Primary
Secondary
Concomitant
Asthma Hospitalization 4/1/2005 Female 2/6/2006 Physician United States
Primary
Concomitant
Muscle Spasms Hospitalization 1/4/2006 Male 2/7/2006 United Kingdom
Primary
Concomitant
Pancreatitis Acute Life Threatening 12/7/2005 47 Male 128 lb 2/9/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Female 2/9/2006 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/1/2005 69 Female 2/10/2006 Consumer Australia
Primary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Death 12/25/2005 57 Male 235 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/31/2006 Female 130 lb 2/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Bone Marrow Failure Other Serious 8/15/2005 Female 220 lb 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Umbilical Hernia Other Serious 11/15/2005 Female 238 lb 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Disease Death Female 3/1/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 1/31/2006 50 Female 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 3/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/31/2006 Female 130 lb 3/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 9/1/2002 Female 3/15/2006 Physician United States
Primary
Concomitant
Bone Cyst Other Serious 7/1/2005 Female 155 lb 3/17/2006 Consumer Canada
Primary
Concomitant
Pyopneumothorax Other Serious 5/28/2005 Female 104 lb 3/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Death Male 128 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Clostridial Infection Hospitalization 2/20/2006 Female 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 2/28/2006 Female 134 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Grand Mal Convulsion Hospitalization 2/1/2006 Female 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/14/2001 Female 253 lb 4/26/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 12/19/2005 Female 123 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 1/31/2006 Female 130 lb 5/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 5/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Pustular Psoriasis Disability 2/16/2006 48 Female 209 lb 5/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Nodule Other Serious 7/1/2005 Female 155 lb 5/24/2006 Physician Canada
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 5/1/2006 Male 185 lb 5/25/2006 Consumer Canada
Primary
Concomitant
Sepsis Hospitalization 73 Female 5/19/2006 Physician United Kingdom
Primary
Concomitant
Death Life Threatening 4/1/2006 Female 187 lb 5/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Photosensitivity Reaction Other Serious 5/3/2006 88 Female 6/1/2006
Primary
Concomitant
Diverticulitis Other Serious 1/1/2006 Female 165 lb 6/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/15/2006 Female 132 lb 6/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 12/11/2005 Female 212 lb 6/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Bone Marrow Failure Other Serious 8/15/2005 Female 220 lb 6/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Other Serious Male 128 lb 6/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/9/2006 Male 176 lb 6/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious Male 128 lb 6/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 3/22/2006 Female 183 lb 6/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 5/2/2006 Male 240 lb 7/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 3/22/2006 Female 183 lb 7/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Life Threatening Female 187 lb 7/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/31/2006 Female 130 lb 7/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious 1/4/2006 Male 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestinal Haemorrhage Other Serious 6/28/2006 Female 8/4/2006 Consumer Canada
Primary
Concomitant
Weight Decreased Other Serious 8/14/2005 Female 132 lb 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 1/10/2006 Female 157 lb 8/14/2006 Physician United Kingdom
Primary
Concomitant
Malignant Anorectal Neoplasm Other Serious 7/11/2005 Female 8/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Disorder Hospitalization Male 210 lb 8/30/2006 Consumer United States
Primary
Concomitant
Thyroid Disorder Other Serious 6/19/2006 65 Female 170 lb 9/5/2006 Other Health Professional Canada
Primary
Concomitant
Basal Cell Carcinoma Other Serious 4/13/2006 Female 126 lb 9/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Heart Valve Replacement Hospitalization 7/13/2006 Male 9/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Female 137 lb 9/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Appendicectomy Hospitalization 3/20/2004 Female 157 lb 9/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestinal Haemorrhage Other Serious 7/12/2006 Female 9/22/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 9/25/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 6/8/2006 78 Female 9/27/2006 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 9/29/2006 Physician United States
Primary
Secondary
Concomitant
Vitreous Floaters 6/29/2006 Female 10/2/2006 Consumer United States
Primary
Concomitant
Neoplasm Malignant Death Female 134 lb 10/16/2006 Physician United States
Primary
Concomitant
Skin Infection Hospitalization 5/1/2005 Female 305 lb 10/19/2006 Physician United States
Primary
Concomitant
Skin Graft Life Threatening 3/1/2005 57 Female 10/16/2006 Netherlands
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Oesophageal Cancer Metastatic Other Serious 7/30/2006 Female 157 lb 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/16/2006 Female 227 lb 11/14/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 7/16/2006 Female 227 lb 11/14/2006 Physician Germany
Primary
Concomitant
Rheumatoid Arthritis Death 7/14/2006 Female 212 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Grand Mal Convulsion Other Serious 5/1/2006 32 Female 11/29/2006 Consumer United States
Primary
Concomitant
Throat Tightness Life Threatening 10/13/2006 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Spinal Cord Compression Hospitalization 6/1/2006 Female 121 lb 12/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Facial Palsy Disability 1/1/2006 60 Female 12/8/2006 Consumer United States
Primary
Concomitant
Death Death 12/7/2006 70 Female 12/15/2006 Consumer Canada
Primary
Concomitant
Panic Attack 7/26/2006 Female 12/18/2006 Consumer United States
Primary
Concomitant
Death Death 12/6/2006 70 Female 12/19/2006 Physician Canada
Primary
Concomitant
Muscular Weakness 8/21/2006 36 Female 198 lb 12/22/2006 Consumer United States
Primary
Concomitant
Intestinal Polyp Other Serious Female 155 lb 1/9/2007 Consumer Canada
Primary
Concomitant
Pleuritic Pain Other Serious 8/1/2006 Female 145 lb 1/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 7/30/2003 50 Female 1/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Death 12/31/2006 Female 134 lb 1/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 11/28/2006 55 Female 176 lb 1/18/2007 Physician France
Primary
Secondary
Concomitant
Spinal Cord Compression Hospitalization 6/1/2006 Female 121 lb 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Bypass Hospitalization 7/15/2006 Male 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 3/22/2006 Female 183 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Dislocation Other Serious 1/8/2005 Female 134 lb 1/22/2007 Consumer United Kingdom
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/31/2006 Female 130 lb 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Clostridial Infection Hospitalization 2/20/2006 Female 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/31/2006 Female 130 lb 1/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 8/1/2003 Female 137 lb 1/25/2007 Consumer United Kingdom
Primary
Concomitant
Pneumonia Other Serious Female 137 lb 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Migraine Hospitalization 1/1/2004 Female 140 lb 2/6/2007 Consumer United States
Primary
Concomitant
Joint Swelling Other Serious 10/15/2004 Male 220 lb 2/7/2007 Consumer United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/1/2006 Female 154 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/6/2006 Female 212 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Other Serious 9/20/2006 Female 194 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Wall Abscess Hospitalization 2/6/2007 56 Female 2/16/2007 Consumer Argentina
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Vasculitic Rash Disability 11/1/2005 60 Female 148 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatic Carcinoma Other Serious 11/1/2006 60 Female 154 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/8/2006 56 Female 2/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/15/2006 Female 176 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thymus Enlargement Hospitalization 1/1/2005 Female 118 lb 3/16/2007 Physician Canada
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2006 Female 165 lb 3/22/2007 Physician Germany
Primary
Concomitant
Wound Other Serious 8/14/2006 Female 137 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Palpitations 61 Female 229 lb 3/27/2007 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 9/30/2005 Female 207 lb 3/30/2007 Consumer United Kingdom
Primary
Concomitant
Thymus Enlargement Hospitalization 1/1/2005 Female 118 lb 4/2/2007 Physician Canada
Primary
Concomitant
Surgery Death 12/31/2006 Female 134 lb 4/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Lower Limb Fracture Hospitalization 3/11/2005 Female 348 lb 4/13/2007 Consumer United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 11/15/2003 Female 4/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Infusion Related Reaction Other Serious 11/24/2006 Female 134 lb 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bowen's Disease Other Serious 5/3/2005 Male 240 lb 5/1/2007 Other Health Professional United States
Primary
Concomitant
Breast Cancer Other Serious Female 134 lb 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2006 Female 165 lb 5/3/2007 Physician Germany
Primary
Concomitant
Abdominal Wall Abscess Hospitalization 2/6/2007 56 Female 5/10/2007 Consumer Argentina
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 12/1/2003 Female 5/18/2007 Consumer United States
Primary
Concomitant
Emphysema Other Serious 1/7/2003 Female 187 lb 5/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Xerosis Hospitalization 11 Male 6/13/2007 Physician United States
Primary
Concomitant
Skin Reaction Other Serious Female 132 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Other Serious 9/8/2006 Male 194 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/9/2007 Female 150 lb 6/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hyperventilation Female 6/22/2007 Consumer United States
Primary
Concomitant
Staphylococcal Infection Death 2/15/2007 Male 132 lb 6/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Disability 7/1/2005 39 Female 6/26/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 9/1/2004 Female 238 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
Food Poisoning Other Serious 8/18/2006 Male 134 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
Splenic Infarction Hospitalization 7/1/2004 68 Female 159 lb 7/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 12/1/2003 Female 7/10/2007 Physician United States
Primary
Concomitant
Staphylococcal Infection Death 2/15/2007 Male 132 lb 7/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/28/2006 Female 207 lb 7/13/2007 United Kingdom
Primary
Concomitant
Hypoaesthesia Other Serious 10/6/2006 Male 181 lb 7/16/2007 Consumer United Kingdom
Primary
Concomitant
Hernial Eventration Hospitalization 7/12/2007 56 Female 7/19/2007 Other Health Professional Argentina
Primary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/20/2007 Consumer United Kingdom
Primary
Concomitant
Hernial Eventration Hospitalization 7/12/2007 56 Female 7/23/2007 Consumer Argentina
Primary
Concomitant
Surgery Death 12/31/2006 Female 134 lb 7/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 12/11/2005 Female 212 lb 7/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 7/27/2005 Female 132 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 8/14/2005 Female 132 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant