Magnesium Sulfate combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 4/26/2006 Female 276 lb 5/30/2006 Physician Germany
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 2/26/2007 Male 173 lb 4/11/2007 Physician United States
Primary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/14/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/17/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/25/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/9/2007 80 Female 5/29/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Retinal Detachment Other Serious 9/10/2006 Male 6/21/2007 Physician United States
Primary
Concomitant
Necrotising Fasciitis Hospitalization 4/28/2007 Female 117 lb 6/27/2007 Physician United States
Primary
Concomitant
Death Death Female 97 lb 7/19/2007 Other Health Professional Canada
Primary
Concomitant
Stomatitis Hospitalization 3/1/2007 Female 203 lb 9/14/2007 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2007 Female 191 lb 10/16/2007 United States
Primary
Concomitant
Tongue Disorder Other Serious 8 Male 10/17/2007 Other Health Professional United States
Primary
Concomitant
Tongue Disorder Other Serious 14 Male 10/17/2007 Other Health Professional United States
Primary
Concomitant
Ocular Hyperaemia Hospitalization 3/1/2007 Female 203 lb 10/23/2007 Consumer United States
Primary
Secondary
Concomitant
Urine Analysis Abnormal Other Serious 53 Male 11/13/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 1/1/2007 67 Female 11/19/2007 Physician Switzerland
Primary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/6/2007 Other Health Professional Portugal
Primary
Secondary
Rheumatoid Arthritis 3/25/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/20/2007 74 152 lb 4/1/2008 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/29/2006 51 Female 98 lb 4/17/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Tricuspid Valve Disease Other Serious 3/20/2008 60 Male 197 lb 5/15/2008 Physician United States
Primary
Secondary
Concomitant
Migraine Other Serious 1/1/2007 Female 215 lb 9/18/2008 Consumer United States
Primary
Concomitant
Transfusion Death 8/3/2007 9/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/1/2007 29 Female 9/25/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2008 Male 200 lb 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/3/2007 24 Male 126 lb 10/20/2008 Consumer Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/24/2008 Female 205 lb 10/16/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 166 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Application Site Irritation 8/12/2008 59 Female 11/10/2008 Consumer United States
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 8/1/2008 53 Female 161 lb 11/21/2008 Physician Australia
Primary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral 8/1/2008 Female 140 lb 12/12/2008 United States
Primary
Concomitant
Injection Site Pain Male 183 lb 12/12/2008 Consumer United States
Primary
Concomitant
Skin Exfoliation 3/1/2008 Female 190 lb 12/12/2008 Consumer United States
Primary
Concomitant
Vomiting 1/1/2008 56 Female 249 lb 12/31/2008 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 9/1/2008 69 Male 2/24/2009 Germany
Primary
Concomitant
Weight Increased Hospitalization 2/2/2009 73 Female 146 lb 2/23/2009 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/27/2009 Female 63 lb 3/4/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 4/18/2007 Female 213 lb 4/3/2009 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2006 Female 147 lb 4/28/2009 Physician United States
Primary
Concomitant
Pain Other Serious 7/1/2007 Female 150 lb 5/18/2009 Consumer United States
Primary
Concomitant
Pain Other Serious 7/1/2007 Female 150 lb 5/20/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 43 5/25/2009 Other Health Professional Canada
Primary
Concomitant
Suicidal Ideation 1/1/2008 Female 6/11/2009
Primary
Secondary
Concomitant
Oedema Peripheral 8/1/2008 Female 140 lb 6/11/2009 United States
Primary
Concomitant
Paraesthesia 9/1/2008 Female 175 lb 6/11/2009 United States
Primary
Concomitant
Skin Discolouration Female 170 lb 6/12/2009 United States
Primary
Concomitant
Hallucination Life Threatening 3/7/2009 30 Male 174 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Stomatitis Death 3/12/2008 Male 126 lb 7/31/2009 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 10/28/2009 56 Female 11/25/2009 Other Health Professional Spain
Primary
Concomitant
Lung Neoplasm Hospitalization 14 Male 95 lb 1/20/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Transfusion Death 8/3/2007 2/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/3/2007 Male 126 lb 2/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Death 3/12/2008 Male 126 lb 3/9/2010 Physician Japan
Primary
Secondary
Concomitant
Paraesthesia Other Serious 13 Male 88 lb 5/3/2010 Other Health Professional Canada
Primary
Concomitant
Visual Impairment Disability 3/11/2009 48 Female 84 lb 4/29/2010 Physician Japan
Primary
Concomitant
Sjogren's Syndrome Other Serious Female 6/25/2010 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Stem Cell Transplant Other Serious 3/11/2009 48 Female 84 lb 7/19/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/21/2009 37 Female 93 lb 8/9/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/20/2007 74 152 lb 8/30/2010 Physician France
Primary
Secondary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 8/29/2007 59 Female 12/2/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 3/11/2009 48 Female 84 lb 11/8/2010 Physician Japan
Primary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/15/2010 54 Female 95 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 54 Female 95 lb 12/27/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/16/2010 14 Female 130 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Death 2/14/2011 62 Female 110 lb 4/8/2011 Physician Japan
Primary
Concomitant
Sepsis Death 8/19/2009 55 Female 121 lb 4/13/2011 Physician Japan
Primary
Concomitant
Toothache Hospitalization 9/21/2009 37 Female 93 lb 4/14/2011 Physician Japan
Primary
Concomitant
Rash Hospitalization 3/15/2010 54 Female 95 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Influenza Life Threatening 2/14/2011 62 Female 110 lb 4/22/2011 Physician Japan
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 8/19/2009 55 Female 121 lb 5/2/2011 Physician Japan
Primary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 3/12/2010 54 Female 95 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Candida Test Positive Hospitalization 3/12/2010 54 Female 95 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Mycobacterial Infection Other Serious 5/3/2011 70 Female 126 lb 6/3/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious Female 5/31/2011 Physician United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 11/1/2009 69 Male 6/8/2011 Consumer United States
Primary
Concomitant
Hip Arthroplasty Other Serious 11/1/2009 69 Male 6/9/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 11/1/2009 69 Male 6/9/2011 Consumer United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pericardial Effusion Life Threatening 10/10/2009 12 Male 92 lb 7/5/2011 Physician Japan
Primary
Concomitant
Melaena Other Serious 10/18/2009 48 Female 97 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Hepatic Failure Hospitalization 6/16/2011 23 Male 307 lb 8/18/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 5/7/2010 70 Male 190 lb 9/22/2011 Consumer Japan
Primary
Concomitant
Hypoxia Other Serious 5/18/2011 50 Female 84 lb 11/23/2011 Physician Japan
Primary
Concomitant
Nausea Other Serious 11/14/1998 60 Female 150 lb 11/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Dysuria Other Serious 11/14/1998 60 Female 150 lb 12/1/2011 Physician United States
Primary
Secondary
Concomitant
Arterial Occlusive Disease Other Serious 1/1/2005 71 Male 12/7/2011 Consumer United States
Primary
Concomitant
Subcutaneous Abscess Hospitalization 10/19/2011 61 Female 132 lb 12/9/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 65 Female 163 lb 12/13/2011 Consumer Australia
Primary
Concomitant
Therapeutic Response Decreased Female 12/13/2011 Physician United States
Primary
Concomitant
Diarrhoea Disability 3/12/2011 67 Female 240 lb 12/14/2011 Australia
Primary
Secondary
Concomitant
Leukopenia Other Serious 2/26/2007 68 Male 173 lb 12/20/2011 Consumer United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/26/2007 68 Male 173 lb 12/27/2011 Consumer United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/26/2007 68 Male 173 lb 12/29/2011 Physician United States
Primary
Secondary
Concomitant
Hypothyroidism Hospitalization 12/5/2011 73 Female 145 lb 1/25/2012 Consumer United States
Primary
Concomitant
Infection Hospitalization 1/29/2009 3 Female 35 lb 2/10/2012 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/10/2011 49 Female 3/9/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 3/21/2012 20 Female 186 lb 3/23/2012 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 16 Female 106 lb 4/2/2012 Pharmacist Canada
Primary
Concomitant
Osteomyelitis Other Serious 2/24/2012 11 Female 116 lb 5/2/2012 Physician United States
Primary
Concomitant
Muscle Atrophy Other Serious 4 Male 35 lb 5/1/2012 Pharmacist Canada
Primary
Concomitant
Hypertension Death 2/24/2012 11 Female 116 lb 5/22/2012 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 11/22/2010 82 Female 75 lb 5/29/2012 Japan
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 4/1/2012 60 Female 117 lb 6/8/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 3/18/2012 45 Female 6/11/2012 Physician United States
Primary
Secondary
Concomitant
Nausea Disability 3/12/2011 67 Female 240 lb 6/26/2012 Physician Australia
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Death 1/29/2009 3 Female 35 lb 7/5/2012 Physician Japan
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 8/27/2011 54 Male 150 lb 7/6/2012 Physician Germany
Primary
Concomitant
Aortic Aneurysm Other Serious 5/23/2012 74 Female 185 lb 7/13/2012 Other Health Professional Canada
Primary
Concomitant
Alveolar Osteitis Other Serious 1/1/2009 32 Male 140 lb 7/27/2012 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 9/21/2009 37 Female 93 lb 4/2/2013 Physician Jp
Primary
Concomitant
Sepsis Death Female 8/27/2012 Physician Be
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 7/27/2012 13 Female 271 lb 11/9/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/28/2012 71 Female 4/22/2013 Consumer Us
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/28/2012 71 Female 11/28/2012 Consumer Us
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 6/20/2012 60 Male 5/1/2013 Other Health Professional Jp
Primary
Concomitant
Tachycardia Hospitalization 3/8/2013 Male 20 lb 3/13/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/8/2013 Male 20 lb 3/11/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Respiratory Arrest Death 11/19/2011 38 Female 99 lb 4/17/2013 Physician Jp
Primary
Secondary
Concomitant
Urinary Tract Infection Death 8/2012 81 Female 121 lb 5/17/2013 Consumer Us
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Life Threatening 11/10/2011 37 Female 5/25/2013 Physician Jp
Primary
Secondary
Concomitant
Varicella Virus Test Positive Life Threatening 11/10/2011 37 Female 5/22/2013 Jp
Primary
Secondary
Concomitant
Haemorrhage Intracranial Other Serious 7/12/2013 67 Male 185 lb 12/27/2013 Physician Us
Primary
Secondary
Concomitant
No Adverse Event 4/10/2013 55 Male 238 lb 11/1/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data