Carboplatin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancytopenia Other Serious 11/15/2004 36 Male 1/10/2006 Consumer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 11/15/2004 36 Male 1/24/2006 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 9/15/2005 63 Male 304 lb 1/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 12/13/2005 58 Female 1/20/2006 France
Primary
Secondary
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
Abdominal Pain Upper 52 Female 1/25/2006 United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/6/2006 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/31/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/24/2005 85 Female 7/26/2006 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 6/2/2006 68 Male 141 lb 8/7/2006 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Female 178 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 2/24/2005 85 Female 8/14/2006 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 6/2/2006 68 Male 141 lb 9/5/2006 Consumer United States
Primary
Secondary
Concomitant
Confusional State Other Serious 10/15/2006 60 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 1/23/2007 United States
Primary
Secondary
Concomitant
Metastasis Death 16 Female 3/5/2007
Primary
Secondary
Glioma Other Serious 16 Female 3/8/2007 Consumer Finland
Primary
Secondary
Nervous System Disorder Death 16 Female 3/2/2007 Physician Germany
Primary
Secondary
Glioma Other Serious 7 Female 3/9/2007 Consumer Finland
Primary
Secondary
Treatment Related Secondary Malignancy Death 16 Female 3/1/2007 Germany
Primary
Secondary
Malignant Neoplasm Progression Other Serious 5/13/2005 63 Female 3/13/2007 Consumer United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/13/2007 Other Health Professional United States
Primary
Secondary
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/13/2007 Other Health Professional United States
Primary
Secondary
Malignant Neoplasm Progression Other Serious 5/13/2005 63 Female 3/16/2007 Consumer United States
Primary
Secondary
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 3/17/2007 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/19/2007 Other Health Professional United States
Primary
Secondary
Glioma Death 16 Female 3/20/2007 Germany
Primary
Secondary
Staphylococcal Sepsis Other Serious 31 Male 4/4/2007 Other Health Professional United States
Primary
Secondary
Tachycardia Other Serious 2/16/2005 17 Male 4/18/2007 Other Health Professional Malaysia
Primary
Secondary
Pneumonia Other Serious Female 4/18/2007 Physician Ireland
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/1/2006 64 Male 4/18/2007 Other Health Professional Japan
Primary
Secondary
Mycobacterial Infection Other Serious 1/1/2003 63 Female 4/18/2007 Other Health Professional Japan
Primary
Secondary
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Penile Pain Hospitalization 12/28/2004 Male 6/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 12/28/2004 Male 6/11/2007 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 12/28/2004 Male 6/16/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 12/28/2004 Male 6/11/2007 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Other Serious Female 8/10/2007 Physician United States
Primary
Secondary
Tachycardia Other Serious 2/16/2005 17 Male 132 lb 8/15/2007 Physician Malaysia
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious Female 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious Female 8/24/2007 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 3 Female 8/29/2007 United Kingdom
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2004 53 Female 9/29/2007 France
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 3 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Myeloid Leukaemia Other Serious 3 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Death 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death Female 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Death 10/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 10/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 70 Female 11/13/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 11/13/2007 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 11/16/2007 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 11/16/2007 Consumer Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 70 Female 11/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 11/29/2007 Consumer France
Primary
Secondary
Concomitant
Stress Death 16 Female 11/21/2007 Germany
Primary
Secondary
Renal Tubular Necrosis Other Serious 53 Male 12/6/2007 Other Health Professional Portugal
Primary
Secondary
Pyrexia Other Serious 12/20/2006 Female 137 lb 12/8/2007 Consumer France
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Large Intestinal Haemorrhage Hospitalization 45 Male 12/28/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 48 Female 1/8/2008 Consumer Japan
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Hospitalization Male 150 lb 2/8/2008 Consumer United Kingdom
Primary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 2/26/2008 Consumer France
Primary
Secondary
Concomitant
Encephalopathy Death 6 Male 2/27/2008 United States
Primary
Secondary
Encephalopathy Death 6 Male 2/29/2008 Other Health Professional United States
Primary
Secondary
Large Intestinal Haemorrhage Hospitalization Male 150 lb 2/29/2008 Consumer United Kingdom
Primary
Concomitant
Encephalopathy Death 6 Male 2/29/2008 United States
Primary
Secondary
Subdural Effusion Death 6 Male 3/5/2008 United States
Primary
Secondary
Encephalopathy Death 6 Male 3/8/2008 United States
Primary
Concomitant
Vision Blurred Death 6 Male 3/1/2008 United States
Primary
Secondary
Encephalopathy Death 6 Male 3/13/2008 United States
Primary
Secondary
Vomiting Other Serious 6 Male 3/15/2008 Physician United States
Primary
Secondary
Concomitant
Viral Diarrhoea Death 6 Male 3/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Hospitalization Male 150 lb 3/26/2008 Consumer United Kingdom
Primary
Concomitant
Vertigo Other Serious 67 Male 3/28/2008
Primary
Secondary
Subdural Effusion Death 1/1/2008 6 Male 3/28/2008 United States
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Systemic Inflammatory Response Syndrome Disability 78 Female 159 lb 4/7/2008 United Kingdom
Primary
Concomitant
Subdural Effusion Other Serious 6 Male 4/16/2008 Consumer United States
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Encephalopathy Death 6 Male 4/21/2008 United States
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/22/2008 Consumer Japan
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 6/27/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/22/2008 Female 103 lb 7/8/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 7/11/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Death 1/1/2005 45 Male 8/12/2008 Physician Japan
Primary
Concomitant
Amyloidosis Death 1/1/2005 45 Male 8/25/2008 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 9/11/2008 Consumer United States
Primary
Secondary
Concomitant
Tooth Injury Other Serious 5/1/2004 49 Male 176 lb 10/13/2008 Physician Denmark
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 10/17/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/30/2008 Female 103 lb 10/23/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 10/29/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/22/2008 Female 10/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 11/5/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/22/2008 56 Female 11/5/2008 Physician Switzerland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/30/2008 Female 103 lb 11/18/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 11/24/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/22/2008 Female 11/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/22/2008 23 Female 137 lb 12/1/2008 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/3/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 12/5/2008 Consumer France
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/22/2008 56 Female 11/25/2008 Physician Switzerland
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/29/2008 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 11/13/2008 62 Male 12/22/2008 Japan
Primary
Concomitant
Loss Of Consciousness Life Threatening 11/13/2008 62 Male 12/23/2008 Physician Japan
Primary
Concomitant
Rash Other Serious 8 Male 2/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Other Serious 8 Male 2/19/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Visual Impairment Other Serious 31 Female 5/5/2009 Other Health Professional Canada
Primary
Secondary
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/12/2009 Pharmacist United States
Primary
Concomitant
Visual Impairment Other Serious 31 Female 5/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 5/20/2009 Pharmacist United States
Primary
Concomitant
Renal Impairment Life Threatening 15 Female 6/4/2009
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2009 Female 169 lb 6/12/2009 United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 11/1/2008 67 Female 7/2/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2009 Female 169 lb 7/1/2009 United States
Primary
Secondary
Concomitant
Immunosuppression Hospitalization 7/1/1997 30 Male 7/20/2009 Other Health Professional Japan
Primary
Secondary
Pneumonia Hospitalization 7/1/1997 30 Male 7/22/2009 Other Health Professional Japan
Primary
Secondary
Pneumonia Other Serious 1/1/1997 23 Male 7/28/2009 Other Health Professional Japan
Primary
Secondary
Pyrexia Other Serious 12/13/2006 Female 137 lb 10/23/2009 Consumer France
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/13/2006 Female 137 lb 10/29/2009 Consumer France
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 10/30/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/4/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 12/4/2009 United States
Primary
Secondary
Thrombocytopenia Other Serious 59 Male 12/10/2009
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 59 Male 12/14/2009
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 12/23/2009 United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/31/2009 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/31/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/12/2009 Female 15 lb 12/30/2009 United States
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Mouth Haemorrhage Life Threatening 12/31/2009 40 Female 1/15/2010 Physician Germany
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Anaemia Other Serious 56 2/2/2010 Consumer Japan
Primary
Secondary
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Anaemia Other Serious 56 2/11/2010 Consumer Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Transformation Hospitalization 55 Female 3/17/2010 Other Health Professional United States
Primary
Secondary
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 55 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Other Serious 55 Female 3/25/2010 Physician United States
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Other Serious 55 Female 3/25/2010 Physician United States
Primary
Secondary

Drug Data