Cisplatin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancytopenia Other Serious 11/15/2004 36 Male 1/10/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/29/2005 68 Female 110 lb 1/5/2006 Physician Japan
Primary
Secondary
Concomitant
Neurotoxicity Death 36 Female 1/5/2006 Physician Turkey
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 11/15/2004 36 Male 1/24/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/29/2005 68 Female 110 lb 1/25/2006 Physician Japan
Primary
Secondary
Concomitant
Swelling Death 36 Female 1/31/2006 Physician Turkey
Primary
Secondary
Vomiting Hospitalization 5/29/2005 68 Female 50 lb 2/6/2006 Physician Japan
Primary
Secondary
Concomitant
Swelling Death 36 Female 2/13/2006 Physician Turkey
Primary
Secondary
Therapy Non-responder Death 36 Female 2/14/2006 Physician Turkey
Primary
Secondary
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
T-cell Lymphoma Hospitalization 36 Female 3/17/2006 Physician Turkey
Primary
Secondary
Abdominal Pain Upper 52 Female 1/25/2006 United States
Primary
Concomitant
Paraesthesia Required Intervention 3/18/2006 Female 90 lb 3/27/2006 Other Health Professional United States
Primary
Concomitant
Neutropenic Sepsis Other Serious 20 Male 139 lb 4/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Hospitalization 25 Female 5/10/2006 Consumer United States
Primary
Secondary
Therapy Non-responder Hospitalization 66 Male 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Death 66 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 16 Male 6/6/2006 Physician United States
Primary
Concomitant
Medical Device Complication Other Serious 6/19/2006 12 Female 97 lb 6/26/2006 Physician Germany
Primary
Concomitant
Movement Disorder Other Serious 6/19/2006 12 Female 97 lb 6/29/2006 Physician Germany
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 36 Female 7/14/2006 Other Health Professional Turkey
Primary
Secondary
Tooth Extraction Other Serious 2/1/2005 72 Male 9/1/2006 United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/1/2006 53 Male 9/15/2006 Physician Japan
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 1/1/2006 53 Male 9/27/2006 Pharmacist Japan
Primary
Secondary
Stomatitis Other Serious 7/1/2006 Female 165 lb 10/9/2006 Physician Belgium
Primary
Concomitant
Febrile Neutropenia Life Threatening 7/1/2006 51 Male 132 lb 10/16/2006 Physician France
Primary
Concomitant
Liver Disorder Hospitalization 10/1/2005 66 Male 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/2/2006 Female 51 lb 11/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/12/2006 Female 165 lb 12/12/2006 Physician Belgium
Primary
Concomitant
Sepsis Death 1/14/2007 Female 14 lb 1/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/30/2007 Female 45 lb 1/31/2007 United States
Primary
Secondary
Vomiting Hospitalization 1/29/2007 6 Female 45 lb 2/20/2007 Physician United States
Primary
Secondary
Metastasis Death 16 Female 3/5/2007
Primary
Secondary
Malignant Neoplasm Progression Other Serious 66 Female 3/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 73 Female 3/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Glioma Other Serious 16 Female 3/8/2007 Consumer Finland
Primary
Secondary
Vomiting Life Threatening 1/29/2007 6 Female 45 lb 3/2/2007 Physician United States
Primary
Secondary
Nervous System Disorder Death 16 Female 3/2/2007 Physician Germany
Primary
Secondary
Glioma Other Serious 7 Female 3/9/2007 Consumer Finland
Primary
Secondary
Treatment Related Secondary Malignancy Death 16 Female 3/1/2007 Germany
Primary
Secondary
Thrombocytopenia Other Serious 2/25/2007 66 Male 3/16/2007 Physician France
Primary
Concomitant
Glioma Death 16 Female 3/20/2007 Germany
Primary
Secondary
Pharyngolaryngeal Pain Male 3/28/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/30/2007 6 Female 45 lb 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 45 Male 143 lb 4/13/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 61 Female 4/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious 7/1/2005 66 Male 5/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/25/2007 66 Male 5/14/2007 Physician France
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 36 Female 5/25/2007 Physician Turkey
Primary
Secondary
Tumour Necrosis Other Serious 17 Male 6/16/2007 United States
Primary
Secondary
Pancreatitis Acute Other Serious 11/1/2004 9 Male 6/29/2007 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 1/1/2002 67 Female 7/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Metastasis Hospitalization 1/1/2002 67 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraparesis Life Threatening 1/1/2002 67 Female 7/20/2007 United Kingdom
Primary
Secondary
Myeloid Leukaemia Other Serious 5 Female 7/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Metastasis Hospitalization 1/1/2002 40 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraparesis Hospitalization 1/1/2002 40 Male 8/3/2007 Argentina
Primary
Secondary
Metastasis Hospitalization 1/1/2002 40 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 1/1/2002 40 Female 8/8/2007 Consumer United States
Primary
Secondary
Movement Disorder Other Serious 6/19/2006 12 Female 97 lb 8/2/2007 Physician Germany
Primary
Concomitant
Pleocytosis Life Threatening 1/1/2002 40 Female 8/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Hepatitis B Other Serious 59 Female 8/10/2007 Japan
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 17 Male 8/9/2007 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 14 Female 8/9/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 70 Female 8/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastasis Other Serious 40 Male 8/10/2007 Physician Argentina
Primary
Secondary
Concomitant
Spinal Anaesthesia Hospitalization 67 Female 8/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Spinal Anaesthesia Life Threatening 1/1/2002 40 Male 8/10/2007 United Kingdom
Primary
Secondary
Renal Failure Acute Other Serious 6/1/2005 66 Male 8/15/2007 Consumer United States
Primary
Secondary
Concomitant
Hepatitis B Other Serious 59 Female 8/17/2007 Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 70 Female 8/20/2007 United Kingdom
Primary
Secondary
Concomitant
Temporomandibular Joint Syndrome Other Serious 17 Male 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 16 Male 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Trismus Other Serious 14 Female 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 10 Female 8/16/2007 Physician United States
Primary
Secondary
Vocal Cord Disorder Other Serious 14 Male 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Spinal Anaesthesia Life Threatening 1/1/2002 40 Male 8/15/2007 United Kingdom
Primary
Secondary
Neutropenia Other Serious 70 Female 8/17/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/1/2005 66 Male 8/28/2007 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3 Male 35 lb 8/28/2007
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 59 Female 8/17/2007 Japan
Primary
Secondary
Spinal Anaesthesia Hospitalization 1/1/2002 40 Female 8/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/1/2005 66 Male 9/4/2007 Consumer Japan
Primary
Secondary
Concomitant
Synovial Sarcoma Other Serious 23 Male 9/6/2007 Other Health Professional Japan
Primary
Secondary
Metastasis Hospitalization 1/1/2002 40 Female 9/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Staphylococcal Infection Other Serious 10/2/2006 45 Male 143 lb 8/31/2007 Physician Japan
Primary
Concomitant
Synovial Sarcoma Other Serious 9/1/1994 23 Male 9/13/2007 Consumer United States
Primary
Secondary
Myelodysplastic Syndrome Death 23 Male 9/7/2007 Physician United Kingdom
Primary
Secondary
Hormone Level Abnormal Other Serious 9/14/2007 Consumer United States
Primary
Secondary
Synovial Sarcoma Other Serious 9/1/1994 23 Male 9/14/2007
Primary
Secondary
Acute Myeloid Leukaemia Death 5 Female 9/12/2007 Physician Brazil
Primary
Secondary
Synovial Sarcoma Other Serious 9/1/1994 23 Male 9/17/2007 Consumer United States
Primary
Secondary
Septic Shock Hospitalization 7/8/2007 Female 99 lb 9/14/2007 United States
Primary
Secondary
Synovial Sarcoma Other Serious 9/1/1994 23 Male 9/20/2007 Japan
Primary
Secondary
Respiratory Failure Other Serious 6/27/2005 65 Male 9/21/2007 Consumer Japan
Primary
Secondary
Concomitant
Sepsis Death 9/18/2007 Physician United Kingdom
Primary
Secondary
Intra-abdominal Haemorrhage Death 9/18/2007 United Kingdom
Primary
Secondary
Sepsis Death 9/18/2007 Physician United Kingdom
Primary
Secondary
Sepsis Death 9/18/2007 Physician United Kingdom
Primary
Secondary
Sepsis Death 9/18/2007 Physician United Kingdom
Primary
Secondary
Pneumonia Bacterial Death Male 9/26/2007 Other Health Professional Japan
Primary
Secondary
Vomiting Other Serious 14 Female 9/26/2007 Other Health Professional United States
Primary
Interacting
Embolism Death Male 9/27/2007 Other Health Professional Japan
Primary
Secondary
Neutropenia Other Serious 67 Male 9/27/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 14 Female 10/2/2007 Other Health Professional United States
Primary
Secondary
Interacting
Vomiting Other Serious 14 Female 10/2/2007
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Death 10/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Death 10/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Other Serious 6/27/2005 65 Male 10/11/2007 Consumer Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/15/2007 Consumer Switzerland
Primary
Secondary
Sepsis Death 10/3/2007 United Kingdom
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Sepsis Death 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Sepsis Death 10/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Death 10/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 10/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 10/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death Male 10/26/2007 United Kingdom
Primary
Secondary
Sepsis Death Unknown 10/22/2007 United Kingdom
Primary
Secondary
Intra-abdominal Haemorrhage Death 10/22/2007 Physician United Kingdom
Primary
Secondary
Intra-abdominal Haemorrhage Death 10/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 11/5/2007 Switzerland
Primary
Secondary
Concomitant
Infective Spondylitis Hospitalization 8/1/2007 70 Male 11/19/2007 Other Health Professional Japan
Primary
Concomitant
Hypersensitivity Other Serious 16 Female 11/20/2007 Other Health Professional Australia
Primary
Secondary
Shock Hospitalization 10/21/2007 Male 84 lb 11/13/2007 United States
Primary
Secondary
Concomitant
Sudden Death Hospitalization 9/22/2007 Male 11/21/2007 Greece
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 10/19/2007 56 Male 11/16/2007 Japan
Primary
Concomitant
Stress Death 16 Female 11/21/2007 Germany
Primary
Secondary
Septic Shock Hospitalization 10/21/2007 Male 84 lb 11/27/2007 United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/1/2001 52 Male 12/10/2007 Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/1/2001 52 Male 12/21/2007 Japan
Primary
Concomitant
Spondylitis Hospitalization 8/1/2007 70 Male 12/21/2007 Other Health Professional Japan
Primary
Concomitant
Stomatitis Other Serious 12/21/2007 Other Health Professional Japan
Primary
Secondary
Renal Failure Acute Other Serious 12/21/2007 Other Health Professional Japan
Primary
Secondary
Pyrexia Other Serious 17 Male 12/28/2007 Other Health Professional France
Primary
Secondary
Renal Failure Acute Other Serious Male 12/31/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/19/2007 Male 62 lb 12/28/2007 United States
Primary
Secondary
Respiratory Disorder Hospitalization 10/19/2007 56 Male 12/28/2007 Consumer Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 8/8/1998 42 Male 1/30/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/10/1999 40 Male 1/30/2008 United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/2/2001 32 Male 1/30/2008 United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious Male 2/19/2008 Consumer Japan
Primary
Secondary
White Blood Cell Count Decreased Death 76 Female 98 lb 2/21/2008 Physician Japan
Primary
Concomitant

Drug Data