Boniva combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain Hospitalization 2/27/2006 Female 150 lb 4/4/2006 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/27/2006 Female 150 lb 4/26/2006 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 5/20/2006 61 Female 159 lb 6/5/2006 Consumer United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 8/1/2005 Female 7/10/2006 Physician United States
Primary
Concomitant
Eye Inflammation Other Serious 3/1/2006 Female 6/15/2006 United States
Primary
Concomitant
Breast Cancer Hospitalization 10/1/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Breast Cancer Hospitalization Female 9/11/2006 Physician United States
Primary
Concomitant
Malignant Melanoma Life Threatening 6/1/2006 60 Female 128 lb 10/31/2006 Physician Greece
Primary
Secondary
Concomitant
Malignant Melanoma Life Threatening 6/1/2006 60 Female 128 lb 12/19/2006 Physician Greece
Primary
Secondary
Concomitant
Fatigue 12/22/2006 39 Female 146 lb 3/27/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 54 Female 150 lb 3/27/2007 Consumer United States
Primary
Concomitant
Breast Cancer Metastatic Life Threatening 12/1/2006 Female 97 lb 5/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 11/9/2006 Female 5/17/2007 Physician Greece
Primary
Concomitant
Hospitalisation Life Threatening 4/27/2007 Female 136 lb 5/13/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Hospitalization 11/9/2006 Female 6/18/2007 Physician Greece
Primary
Secondary
Concomitant
Pyrexia Death 6/28/2007 Male 126 lb 7/12/2007 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 9/1/2006 Male 164 lb 7/27/2007 Physician United States
Primary
Concomitant
Pyrexia Death 6/28/2007 Male 126 lb 9/12/2007 Physician United States
Primary
Concomitant
Localised Infection 11/1/2006 Male 150 lb 12/10/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema 6/21/2007 Female 174 lb 12/13/2007 Physician United States
Primary
Concomitant
Pain In Extremity 1/1/2005 Male 12/15/2007 Physician United States
Primary
Concomitant
Rash Other Serious 8/15/2007 Female 1/2/2008 Consumer United States
Primary
Concomitant
Rash Other Serious 8/15/2007 Female 114 lb 1/22/2008 Consumer United States
Primary
Concomitant
Splenomegaly Other Serious 6/1/2007 Female 144 lb 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 4/1/2007 64 Female 107 lb 1/30/2008 Consumer United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 65 Female 2/25/2008 Physician United States
Primary
Concomitant
Convulsion Other Serious 65 Female 2/25/2008 Physician United States
Primary
Concomitant
Viral Infection Other Serious 4/1/2007 Female 107 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Asthma Other Serious 12/6/2007 Female 160 lb 3/26/2008 Other Health Professional United States
Primary
Concomitant
Retinal Detachment Other Serious 4/1/2007 Male 203 lb 5/2/2008 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 68 Female 5/6/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 5/1/2007 Female 198 lb 5/19/2008 Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/22/2008 Female 122 lb 5/23/2008 Other Health Professional United States
Primary
Concomitant
Osteopenia Other Serious 4/1/2007 64 Female 6/30/2008 Physician United States
Primary
Concomitant
Osteonecrosis Disability 6/12/2008 65 Male 7/9/2008 Physician Switzerland
Primary
Concomitant
Renal Disorder Other Serious Female 178 lb 7/16/2008 Physician United States
Primary
Concomitant
Death Hospitalization 6/8/2008 Male 141 lb 7/18/2008 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 3/14/2008 Female 92 lb 7/28/2008 Physician United States
Primary
Secondary
Concomitant
Pleuritic Pain Hospitalization 6/20/2008 74 Male 220 lb 8/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thyroid Neoplasm Other Serious 5/19/2004 Female 184 lb 8/8/2008 Physician United States
Primary
Concomitant
Ligament Rupture Other Serious 11/1/2007 Female 167 lb 8/12/2008 Other Health Professional United States
Primary
Concomitant
Pleuritic Pain Hospitalization 6/20/2008 74 Male 220 lb 8/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Other Serious 5/1/2008 68 Female 9/3/2008 Consumer Hungary
Primary
Secondary
Concomitant
Swelling Face Other Serious 5/1/2008 68 Female 9/8/2008 Consumer Hungary
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 6/1/2008 Female 177 lb 9/17/2008 Consumer United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious Female 9/22/2008 Physician Germany
Primary
Concomitant
Ligament Rupture Other Serious 11/1/2007 Female 167 lb 9/26/2008 Other Health Professional United States
Primary
Concomitant
Bronchospasm Other Serious 71 Female 11/11/2008 Consumer United States
Primary
Concomitant
Vomiting 1/1/2008 Female 216 lb 12/2/2008 Physician United States
Primary
Concomitant
Memory Impairment 5/1/2008 Female 162 lb 12/13/2008 Physician United States
Primary
Secondary
Concomitant
Pain 10/24/2007 Female 240 lb 12/15/2008 Physician United States
Primary
Concomitant
Insomnia 1/1/2008 66 Male 172 lb 12/30/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 9/9/2008 66 Female 12/31/2008 Consumer United States
Primary
Concomitant
Rash Pruritic 10/30/2008 65 Female 12/31/2008 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 12/13/2008 Female 1/6/2009 Other Health Professional United States
Primary
Concomitant
Sensation Of Heaviness 9/1/2008 Female 1/16/2009 Consumer
Primary
Concomitant
Rash Other Serious 10/1/2007 Female 114 lb 1/23/2009 Physician United States
Primary
Concomitant
Systemic Candida Hospitalization 11/10/2008 Female 115 lb 1/30/2009 Belgium
Primary
Secondary
Concomitant
Urticaria Other Serious 12/13/2008 Female 2/4/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 11/24/2008 68 Female 159 lb 2/9/2009 Greece
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 8/1/2008 68 Female United States
Primary
Concomitant
Synovial Cyst Hospitalization 9/16/2008 74 Male 146 lb 2/20/2009 Greece
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 11/3/2008 74 Male 146 lb 2/23/2009 Greece
Primary
Concomitant
Transfusion Reaction Other Serious 7/1/2008 56 Female 2/24/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/17/2007 Female 2/25/2009 Consumer United States
Primary
Concomitant
Systemic Candida Hospitalization 11/10/2008 Female 115 lb 3/9/2009 Belgium
Primary
Secondary
Concomitant
Transfusion Reaction Other Serious 7/1/2008 56 Female 3/9/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2008 Female 3/14/2009 Other Health Professional United States
Primary
Concomitant
Procedural Complication 12/11/2008 Female 135 lb 3/14/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 12/30/2008 Female 200 lb 3/14/2009 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 1/1/2008 Female 160 lb 3/14/2009 Consumer United States
Primary
Concomitant
Nail Dystrophy Disability 1/1/2007 70 Female 161 lb 3/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Eye Disorder 75 Female 3/18/2009 Consumer United States
Primary
Concomitant
Breast Cancer Other Serious 11/7/2008 53 Female 176 lb 3/20/2009 Physician Germany
Primary
Concomitant
Transfusion Reaction Hospitalization 7/1/2008 56 Female 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2009 Female 3/25/2009 Physician Hungary
Primary
Concomitant
Pyrexia Disability 3/6/2009 63 Female 165 lb 4/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Disorder 3/1/2009 Female 4/23/2009 Consumer
Primary
Concomitant
Arrhythmia Death 3/28/2009 Male 248 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/7/2009 80 Female 128 lb 5/14/2009 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Osteonecrosis Disability 1/7/2009 80 Female 128 lb 5/22/2009 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Systemic Candida Hospitalization 11/10/2008 Female 115 lb 6/1/2009 Belgium
Primary
Secondary
Concomitant
Pain 1/1/2009 Female 115 lb 6/12/2009 Physician United States
Primary
Concomitant
Drug Ineffective 3/1/2009 Female 161 lb 6/12/2009 United States
Primary
Concomitant
Rheumatoid Arthritis 4/1/2009 Female 6/12/2009 Consumer United States
Primary
Concomitant
Osteonecrosis Disability 6/12/2008 65 Male 6/17/2009 Physician Switzerland
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/4/2003 Male 150 lb 6/18/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Insomnia 75 Female 6/19/2009 Consumer United States
Primary
Concomitant
Tooth Fracture Other Serious 9/28/2005 68 Female 123 lb 4/20/2009 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2009 Female 184 lb 7/6/2009 Physician United States
Primary
Concomitant
Expired Drug Administered Hospitalization 3/1/2009 70 Female 7/15/2009 United States
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 11/10/2008 Female 115 lb 7/24/2009 Belgium
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/10/2008 Female 115 lb 8/13/2009 Belgium
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/27/2008 Female 141 lb 8/19/2009 Physician Philippines
Primary
Secondary
Concomitant
Vasculitis Other Serious 1/1/2004 Female 8/20/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 1/30/2007 Female 190 lb 9/11/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 9/1/2008 Female 9/12/2009 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Stiffness 5/18/2009 Female 116 lb 9/18/2009 Consumer United States
Primary
Concomitant
Injection Site Irritation 5/1/2009 Female 200 lb 9/18/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 6/24/2009 Male 145 lb 9/19/2009 Consumer United States
Primary
Concomitant
Sinus Disorder 6/26/2009 Female 132 lb 9/19/2009 Consumer United States
Primary
Concomitant
Emphysema Female 152 lb 9/19/2009 United States
Primary
Concomitant
Wound Haemorrhage 4/1/2009 Female 9/19/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 4/1/2009 165 lb 9/19/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 8/23/2009 Female 9/19/2009 Consumer United States
Primary
Concomitant
Breast Cancer Female Other Serious 9/2/2009 59 Female 120 lb 9/10/2009 Physician United States
Primary
Secondary
Concomitant
Hand Fracture Hospitalization 8/1/2009 Female 132 lb 9/24/2009 United States
Primary
Concomitant
Optic Neuropathy Other Serious 1/1/2003 Male 10/5/2009 Other Health Professional Finland
Primary
Secondary
Concomitant
Atrial Fibrillation Life Threatening 8/1/2009 70 Female 10/13/2009 Physician Greece
Primary
Concomitant
Atrial Fibrillation 8/1/2009 70 Female 10/23/2009 Physician Greece
Primary
Concomitant
Diabetes Mellitus Other Serious 4/1/2009 Female 130 lb 10/23/2009 Consumer United States
Primary
Concomitant
Venous Thrombosis Other Serious 4/1/2007 Female 11/3/2009 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 Female 138 lb 11/6/2009 United States
Primary
Concomitant
Stress Cardiomyopathy Hospitalization 11/10/2008 Female 115 lb 11/6/2009 Belgium
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/10/2008 Female 115 lb 11/9/2009 Belgium
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/10/2008 Female 115 lb 11/16/2009 Belgium
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/10/2008 Female 115 lb 11/25/2009 Belgium
Primary
Secondary
Concomitant
Bronchioloalveolar Carcinoma Hospitalization 2/1/2009 Female 109 lb 11/30/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Warmth Female 12/7/2009 Pharmacist United States
Primary
Concomitant
Osteoarthritis 2/25/2009 Female 151 lb 12/8/2009 Physician United States
Primary
Concomitant
Glaucoma 7/1/2008 Female 160 lb 12/9/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased 1/1/2006 Female 183 lb 12/9/2009 Physician United States
Primary
Concomitant
Viral Infection 5/1/2009 Female 201 lb 12/10/2009 Physician United States
Primary
Concomitant
Osteonecrosis Disability 1/7/2009 80 Female 128 lb 12/16/2009 Switzerland
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 11/19/2009 Female 12/22/2009 Physician United States
Primary
Concomitant
Osteoporosis Other Serious 3/12/2002 Female 12/23/2009 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 10/25/2009 58 Female 1/7/2010 Physician Italy
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 1/1/2004 Female 1/8/2010 Physician United States
Primary
Concomitant
Therapy Regimen Changed Other Serious Female 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 1/1/2004 Female 127 lb 1/13/2010 Physician United States
Primary
Concomitant
Pain 10/1/2009 Female 130 lb 1/30/2010 United States
Primary
Concomitant
Weight Decreased Disability 9/9/2009 Female 126 lb 2/4/2010 Physician Ireland
Primary
Concomitant
Drug Ineffective Hospitalization 10/25/2009 58 Female 2/12/2010 Physician Italy
Primary
Secondary
Concomitant
B-cell Lymphoma Other Serious 9/1/2009 Female 170 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/10/2008 Female 115 lb 3/5/2010 Belgium
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Postoperative Wound Infection Other Serious 8/1/2009 Female 121 lb 3/15/2010 United Kingdom
Primary
Concomitant
Depression Other Serious 1/1/2010 71 Female 3/23/2010 Physician Switzerland
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Depression Other Serious 1/1/2010 71 Female 3/28/2010 Physician Switzerland
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 10/25/2009 58 Female 3/30/2010 Physician Italy
Primary
Secondary
Concomitant
Oedema 1/28/2010 54 Female 4/12/2010 Consumer United States
Primary
Concomitant
Fatigue Female 4/12/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 4/14/2010 United States
Primary
Secondary
Concomitant

Drug Data