Methotrexate combined with Rheumatrex

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tuberculous Pleurisy Hospitalization 8/23/2005 Female 2/6/2006 Physician Japan
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 57 Male 225 lb 2/22/2006 Lawyer United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2002 57 Male 225 lb 2/27/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2002 57 Male 225 lb 3/29/2006 Physician United States
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 6/22/2005 Female 4/3/2006 Physician Japan
Primary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 11/27/2003 Female 95 lb 4/20/2006 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 10/29/2005 Female 5/12/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Infection Other Serious 3/14/2005 Male 121 lb 5/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/26/2006 Female 123 lb 6/6/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 6/27/2006 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 7/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/3/2006 Female 106 lb 7/17/2006 Physician Japan
Primary
Secondary
Lymphoma Hospitalization 2/14/2005 Female 99 lb 9/11/2006 Physician Japan
Primary
Concomitant
Peritoneal Tuberculosis Other Serious 12/26/2003 Female 9/14/2006 Physician Japan
Primary
Concomitant
Peritonitis Death 11/6/2005 Female 119 lb 9/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/26/2006 Female 123 lb 10/3/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 10/11/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 6/22/2005 Female 163 lb 11/7/2006 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 6/20/2006 Female 104 lb 1/3/2007 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 6/20/2006 Female 104 lb 2/6/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Death 11/6/2005 Female 119 lb 2/12/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/16/2007 Female 90 lb 2/27/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Death 2/24/2005 Female 119 lb 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 3/12/2007 Female 97 lb 4/10/2007 Physician Japan
Primary
Secondary
Concomitant
Death Death Female 101 lb 4/11/2007 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 5/16/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 10/22/2003 Male 110 lb 5/25/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 9/2/2003 Male 159 lb 6/12/2007 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 9/29/2006 Male 141 lb 8/16/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 12/20/2006 Female 84 lb 8/31/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/14/2005 Male 104 lb 9/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/20/2006 Female 84 lb 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 9/24/2007 44 Female 108 lb 11/5/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Other Serious 9/24/2007 Female 112 lb 11/9/2007 Physician Japan
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 1/22/2008 Physician Japan
Primary
Concomitant
Infusion Related Reaction 3/12/2007 Female 97 lb 2/11/2008 Physician Japan
Primary
Secondary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 2/11/2008 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/3/2007 Female 123 lb 2/12/2008 Physician Japan
Primary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 4/14/2005 Female 99 lb 3/7/2008 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 4/11/2005 Female 112 lb 4/11/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death Female 101 lb 5/23/2008 Physician Japan
Primary
Concomitant
Central Nervous System Lymphoma Other Serious 2/1/2006 Female 117 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 2/1/2006 Female 117 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 2/1/2006 Female 117 lb 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/1/2007 Female 110 lb 10/23/2008 Physician Japan
Primary
Concomitant
Reflux Oesophagitis Hospitalization 3/4/2007 Female 146 lb 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/1/2008 58 Female 11/14/2008 Other Health Professional Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 3/16/2007 Female 152 lb 11/19/2008 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/19/2008 Female 11/24/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/20/2004 Male 121 lb 1/26/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/19/2008 Female 1/26/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/20/2004 Male 121 lb 2/4/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 167 lb 2/13/2009 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 167 lb 4/24/2009 Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/26/2008 Female 104 lb 6/10/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/18/2007 Female 104 lb 6/23/2009 Physician Japan
Primary
Secondary
Concomitant
Ovarian Epithelial Cancer Hospitalization 2/18/2009 Female 119 lb 6/25/2009 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 5/19/2008 Female 6/29/2009 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Test Positive Other Serious 6/29/2008 Female 115 lb 7/9/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/11/2009 Female 7/27/2009 Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 5/11/2009 Female 8/4/2009 Japan
Primary
Secondary
Concomitant
Sigmoiditis Life Threatening 11/28/2008 42 Female 10/19/2009 Other Health Professional France
Primary
Secondary
Rheumatoid Lung Hospitalization 5/11/2009 Female 10/22/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/20/2009 Female 12/14/2009 Physician Japan
Primary
Secondary
Rheumatoid Lung Hospitalization 6/3/2009 Female 12/14/2009 Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/29/2009 Female 99 lb 12/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ovarian Epithelial Cancer Hospitalization 2/18/2009 Female 119 lb 1/5/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 11/10/2009 Male 128 lb 1/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 12/3/2009 Female 110 lb 1/13/2010 Physician Japan
Primary
Secondary
Cerebral Haemorrhage Other Serious 11/16/2009 Female 1/21/2010 Physician Japan
Primary
Concomitant
Lymphoma Hospitalization 9/22/2009 Female 99 lb 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Ovarian Epithelial Cancer Hospitalization 2/18/2009 Female 119 lb 2/12/2010 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 5/19/2008 Female 2/19/2010 Physician Japan
Primary
Secondary
Concomitant
Ovarian Epithelial Cancer Hospitalization 2/18/2009 Female 119 lb 3/1/2010 Physician Japan
Primary
Concomitant
Tuberculosis Test Positive Other Serious 6/29/2008 Female 115 lb 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 11/10/2009 Male 128 lb 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 9/8/2009 Female 99 lb 3/14/2010 Physician Japan
Primary
Concomitant
Vascular Purpura Hospitalization 9/8/2009 Female 99 lb 3/25/2010 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 9/22/2009 Female 99 lb 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/19/2008 60 Female 4/2/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 12/3/2009 79 Female 110 lb 4/6/2010 Physician Japan
Primary
Secondary
Rash Hospitalization 5/15/2009 58 Female 106 lb 5/6/2010 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 7/7/2008 15 Female 95 lb 5/19/2010 Physician Japan
Primary
Concomitant
Hypercholesterolaemia Other Serious 11/10/2009 56 Female 5/27/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 12/3/2009 79 Female 110 lb 5/28/2010 Physician Japan
Primary
Secondary
Vestibular Disorder Congenital Anomaly 11/1/2009 84 Male 6/11/2010 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Other Serious 6/16/2010 53 Female 123 lb 6/25/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 4/1/2010 85 Male 131 lb 6/25/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 6/16/2010 53 Female 123 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Vestibular Disorder 11/1/2009 84 Male 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 7/16/2010 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased 1/25/2010 68 Female 75 lb 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 6/16/2010 53 Female 123 lb 7/26/2010 Physician Japan
Primary
Secondary
Concomitant
Nodule Other Serious 2/1/2002 66 Female 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 11/24/2006 51 Male 115 lb 8/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 4/28/2010 43 Female 110 lb 8/20/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 11/24/2006 51 Male 115 lb 8/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Tuberculosis Other Serious 7/24/2006 72 Male 117 lb 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Life Threatening 4/8/2010 67 Male 121 lb 9/7/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 4/26/2006 56 Female 123 lb 9/20/2010 Physician Japan
Primary
Secondary
Concomitant
Sapho Syndrome Hospitalization 4/1/2010 57 Female 117 lb 10/11/2010 Physician Japan
Primary
Concomitant
Tuberculous Pleurisy Other Serious 4/1/2010 63 Male 106 lb 10/12/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/13/2009 15 Female 97 lb 10/13/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Death 12/1/2008 55 Male 169 lb 10/19/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 6/16/2010 53 Female 123 lb 10/26/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/29/2010 11/1/2010 Physician Japan
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 9/8/2009 39 Female 99 lb 11/16/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/1/2008 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcus Test Positive Hospitalization 1/1/2010 11/18/2010 Physician Japan
Primary
Secondary
Concomitant
Sapho Syndrome Hospitalization 5/12/2010 57 Female 117 lb 12/3/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 4/1/2010 12/10/2010 Other Health Professional Japan
Primary
Secondary
Tuberculous Pleurisy Other Serious 4/1/2010 63 Male 106 lb 12/20/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 3/31/2009 1/20/2011 Other Health Professional Japan
Primary
Concomitant
Gastroenteritis Hospitalization 7/20/2010 62 Female 115 lb 2/4/2011 Physician Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 9/22/2009 62 Female 99 lb 2/23/2011 Physician Japan
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 7/20/2010 62 Female 115 lb 4/12/2011 Physician Japan
Primary
Secondary
Concomitant
Disseminated Tuberculosis Hospitalization 2/2/2011 86 Female 93 lb 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 3/30/2011 50 Female 4/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Headache Death 6/12/2009 70 Male 162 lb 5/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 3/30/2011 50 Female 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Eczema Death 6/12/2009 70 Male 162 lb 6/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 4/21/2011 50 Female 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 11/6/2008 56 Male 152 lb 6/4/2011 Physician Japan
Primary
Concomitant
Altered State Of Consciousness Hospitalization 3/26/2011 54 Female 110 lb 6/13/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 3/26/2011 54 Female 110 lb 6/28/2011 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Death 3/1/2010 63 Male 8/5/2011 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Other Serious 12/13/2010 50 Female 9/30/2011 Japan
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 10/1/2011 65 Male 157 lb 11/9/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 11/15/2011 63 Male 12/2/2011 Physician Japan
Primary
Concomitant
Drug Ineffective Death 11/15/2011 63 Male 12/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 11/15/2011 63 Male 12/14/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/22/2011 66 Female 12/28/2011 Physician Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 12/13/2010 50 Female 12/29/2011 Japan
Primary
Concomitant
Pneumothorax Death 1/1/2010 71 Male 101 lb 12/26/2011 Physician Japan
Primary
Secondary
Concomitant
Immunosuppression Other Serious 1/1/2010 71 Male 101 lb 1/13/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 11/15/2011 63 Male 1/31/2012 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 11/18/2011 82 Female 77 lb 2/8/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/21/2005 64 Male 128 lb 2/14/2012 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/1/2011 81 Female 77 lb 3/1/2012 Physician Japan
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 12/8/2011 39 Female 130 lb 3/23/2012 Physician Japan
Primary
Secondary
Concomitant
Anaemia Macrocytic Other Serious 12/27/2011 56 Male 4/2/2012 Physician Japan
Primary
Secondary
Concomitant
Necrotising Oesophagitis Other Serious 1/1/2011 81 Female 77 lb 4/6/2012 Physician Japan
Primary
Secondary
Concomitant
Collagen Disorder Hospitalization 12/8/2011 39 Female 130 lb 4/11/2012 Physician Japan
Primary
Secondary
Concomitant
Diverticulitis Intestinal Haemorrhagic Hospitalization 8/24/2009 62 Female 4/17/2012 Japan
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 4/28/2009 75 Female 4/27/2012 Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2012 78 Female 4/30/2012 Consumer Japan
Primary
Concomitant

Drug Data