Aciphex combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Herpes Zoster Other Serious 1/1/2005 Female 120 lb 1/9/2006 Physician United States
Primary
Concomitant
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 1/13/2006 Physician United States
Primary
Concomitant
Ankle Fracture Other Serious 8/1/2005 Female 281 lb 1/24/2006 Physician United States
Primary
Concomitant
Lymphoma Other Serious 10/1/2005 Female 143 lb 1/24/2006 Other Health Professional United States
Primary
Concomitant
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 2/3/2006 Physician United States
Primary
Concomitant
Postoperative Wound Infection Other Serious Female 210 lb 2/7/2006 Physician United States
Primary
Concomitant
Lymphoma Other Serious 10/1/2005 Female 141 lb 2/15/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/1/2005 41 Male 202 lb 1/23/2006 Pharmacist United States
Primary
Concomitant
Pseudocyst Hospitalization 1/1/2006 Female 3/21/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/1999 50 Male 240 lb 4/5/2006 Physician United States
Primary
Concomitant
Urticaria Hospitalization 8/30/2001 47 Male 187 lb 4/6/2006 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 50 Female 5/17/2006 United States
Primary
Concomitant
Cryptococcosis Hospitalization 11/3/2005 72 Male 195 lb 5/30/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 12/30/2005 Female 6/9/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 11/7/2002 Female 6/9/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization Male 6/12/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 5/3/2006 Female 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Blood Creatinine Increased 5/10/2006 71 Female 6/30/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/20/2006 71 Female 9/6/2006 Physician United States
Primary
Concomitant
Respiratory Tract Carcinoma In Situ Death Male 212 lb 9/26/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Herpes Zoster 5/18/2006 71 Female 196 lb 10/2/2006 Consumer United States
Primary
Concomitant
Urticaria 6/20/2006 47 Female 139 lb 10/2/2006 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 9/1/2006 Male 170 lb 11/7/2006 Physician United States
Primary
Concomitant
Pyrexia Other Serious 9/1/2006 Male 170 lb 11/21/2006 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 3/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/26/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Tonsil Cancer Other Serious 1/1/2006 Female 182 lb 12/13/2006 Physician United States
Primary
Concomitant
Death Death 11/22/2006 77 Female 12/8/2006 Physician United States
Primary
Concomitant
Rash Erythematous 10/16/2006 Female 12/20/2006 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 9/1/2006 Male 170 lb 12/22/2006 Physician United States
Primary
Concomitant
Fatigue 7/17/2006 62 Female 201 lb 12/22/2006 Physician United States
Primary
Concomitant
Tendon Rupture Hospitalization 6/9/2006 Female 179 lb 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/1/2005 52 Male 182 lb 4/2/2007 Consumer United States
Primary
Concomitant
Respiratory Arrest Death 11/22/2006 77 Female 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 1/1/2007 Female 150 lb 4/13/2007 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/1998 Female 4/17/2007 Physician United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/1998 Female 4/26/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/8/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/10/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 3/6/2007 79 Female 146 lb 5/11/2007 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 46 Female 112 lb 5/25/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 10/28/2006 42 Male 1/14/2007 Pharmacist United States
Primary
Secondary
Concomitant
Procedural Complication Hospitalization 3/1/2007 Female 187 lb 6/14/2007 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 6/29/2007 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 54 Female 125 lb 6/30/2007 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 7/3/2007 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 7/24/2007 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/1/2004 46 Female 112 lb 8/2/2007 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 8/7/2007 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 9/27/2007 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 7/19/2007 Female 10/2/2007 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 7/19/2007 Female 10/12/2007 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2006 Female 10/4/2007 Consumer United States
Primary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 11/1/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2005 Female 127 lb 11/2/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/1/2005 Female 152 lb 11/27/2007 Physician United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Hospitalization 10/1/2005 Female 206 lb 12/6/2007 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 144 lb 12/6/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/6/2006 Male 12/6/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/15/2006 Female 200 lb 12/6/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/1/2005 Female 152 lb 2/28/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 Female 143 lb 3/25/2008 Physician United States
Primary
Concomitant
Asthma Other Serious 12/6/2007 Female 160 lb 3/26/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 Female 143 lb 4/8/2008 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 6/5/2008 Physician United States
Primary
Concomitant
Tuberculosis Death 10/1/2007 Female 146 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 7/16/2008 Physician United States
Primary
Concomitant
Deafness Neurosensory Disability 6/14/2008 68 Female 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 144 lb 8/4/2008 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 143 lb 8/12/2008 Physician United States
Primary
Concomitant
Deafness Neurosensory Disability 6/14/2008 68 Female 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 1/20/2007 Female 8/14/2008 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 136 lb 8/25/2008 United States
Primary
Concomitant
Renal Failure Other Serious 4/13/2003 Female 9/16/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 61 Female 136 lb 9/8/2008 United States
Primary
Concomitant
Renal Failure Other Serious 4/13/2003 Female 10/3/2008 Physician United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 12/27/1999 46 Female 112 lb 10/10/2008 Physician United States
Primary
Concomitant
Urticaria Hospitalization 1/20/2007 Female 143 lb 10/27/2008 Lawyer United States
Primary
Concomitant
Urticaria Hospitalization 1/20/2007 Female 143 lb 11/5/2008 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 1/20/2007 Female 143 lb 11/14/2008 Other Health Professional United States
Primary
Concomitant
Onychomycosis 10/16/2007 Female 119 lb 12/15/2008 Physician United States
Primary
Concomitant
Pain 10/19/2007 Female 12/15/2008 Physician United States
Primary
Concomitant
Sudden Death Death 9/9/2008 Female 1/19/2009 United States
Primary
Concomitant
Syncope Life Threatening 7/2/2008 63 Female 1/26/2009 Pharmacist United States
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 2/26/2009 United States
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 3/10/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 3/12/2009 Physician United States
Primary
Concomitant
Incorrect Dose Administered 12/18/2008 Male 169 lb 3/14/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 9/9/2008 Female 4/3/2009 United States
Primary
Concomitant
Tenosynovitis Other Serious 8/1/2007 73 Male 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/10/2009 Female 271 lb 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Fatigue 1/21/2009 41 Female 170 lb 5/15/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 4/1/2009 Female 6/12/2009 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2008 Male 330 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Pruritus 7/6/2009 Female 165 lb 9/19/2009 Physician United States
Primary
Concomitant
Drug Dose Omission 8/7/2009 Male 190 lb 9/19/2009 Consumer United States
Primary
Concomitant
Crohn's Disease Hospitalization 9/23/2009 Female 121 lb 10/19/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 9/23/2009 Female 121 lb 10/20/2009 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 4/1/2009 Female 130 lb 10/23/2009 Consumer United States
Primary
Concomitant
Crohn's Disease Hospitalization 12/8/2009 Female 121 lb 12/23/2009 Physician United States
Primary
Concomitant
Skin Nodule Other Serious 10/1/2009 Female 166 lb 12/31/2009 Physician United States
Primary
Concomitant
Constipation Other Serious 12/18/2009 Male 1/21/2010 Physician United States
Primary
Concomitant
Laboratory Test Abnormal Other Serious 1/6/2010 Female 148 lb 1/22/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/19/2000 Female 145 lb 1/28/2010 United States
Primary
Secondary
Concomitant
Drug Effect Decreased 11/1/2008 Female 144 lb 1/29/2010 Physician United States
Primary
Concomitant
Nasal Oedema 9/10/2009 Female 185 lb 1/29/2010 United States
Primary
Concomitant
Rash Pruritic 9/17/2009 Female 103 lb 1/30/2010 United States
Primary
Concomitant
Serum Sickness Other Serious 10/1/2009 Female 166 lb 2/10/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2009 62 Female 120 lb 4/14/2010 United States
Primary
Concomitant
Breast Cancer Other Serious 2/24/2010 62 Female 169 lb 4/22/2010 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 2/24/2010 62 Female 169 lb 4/27/2010 Physician United States
Primary
Concomitant
Cerebrovascular Accident Life Threatening 10/19/2009 66 Male 200 lb 4/30/2010 Physician United States
Primary
Concomitant
Fistula Hospitalization 5/1/2010 57 Male 193 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/19/2000 54 Female 145 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Female 145 lb 5/11/2010 Other Health Professional United States
Primary
Concomitant
Fistula Hospitalization 5/1/2010 57 Male 193 lb 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 5/1/2010 57 Male 193 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant
Viral Infection Female 145 lb 7/26/2010 Other Health Professional United States
Primary
Concomitant
Panic Attack 8/17/2009 51 Female 9/16/2010 Consumer United States
Primary
Concomitant
Stent Placement Other Serious 9/1/2010 55 Male 320 lb 10/8/2010 Other Health Professional United States
Primary
Concomitant
Lung Neoplasm Other Serious 3/15/2009 10/29/2010 Physician United Kingdom
Primary
Concomitant
Stent Placement Other Serious 9/1/2010 55 Male 320 lb 11/1/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 1/1/2010 12/1/2010 Physician United States
Primary
Concomitant
Lupus-like Syndrome Other Serious 10/26/2010 41 Female 265 lb 12/16/2010 Other Health Professional United States
Primary
Concomitant
Nausea 7/1/2010 54 Female 199 lb 11/6/2010 Consumer United States
Primary
Concomitant
Bronchitis Hospitalization Male 240 lb 1/28/2011 Consumer United States
Primary
Concomitant
Arthralgia 2/1/2010 63 Male 185 lb 1/28/2011 United States
Primary
Concomitant
Injection Site Pain Other Serious 1/1/2009 60 Female 170 lb 1/29/2011 Physician United States
Primary
Secondary
Concomitant
Hearing Impaired 5/25/2010 70 Female 1/29/2011 Consumer United States
Primary
Concomitant
Dyspnoea 11/1/2009 43 192 lb 1/30/2011 Consumer United States
Primary
Concomitant
Nasopharyngitis 50 Female 1/30/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 9/29/2010 57 Male 1/30/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 7/1/2010 55 Female 1/30/2011 Consumer United States
Primary
Concomitant
Enterocutaneous Fistula Hospitalization 5/1/2010 57 Male 193 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Osteochondritis Hospitalization 12/27/1999 46 Female 112 lb 3/1/2011 Physician United States
Primary
Concomitant
Malaise 69 Female 3/8/2011 Consumer United States
Primary
Concomitant
Pain In Extremity Disability 1/1/2010 43 Female 143 lb 3/23/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2010 43 Female 143 lb 3/28/2011 Consumer United States
Primary
Concomitant
Headache Hospitalization 2/1/2009 53 Female 185 lb 4/4/2011 Consumer United States
Primary
Secondary
Concomitant
Fatigue Female 145 lb 2/7/2011 Other Health Professional United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 2/24/2010 62 Female 169 lb 4/25/2011 Physician United States
Primary
Concomitant
Surgery Hospitalization 2/1/2011 64 Male 245 lb 5/19/2011 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 2/4/2011 42 Female 5/26/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 4/1/2011 70 Male 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 4/1/2011 70 Male 214 lb 6/13/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 4/1/2011 70 Male 6/17/2011 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2005 78 Female 190 lb 6/20/2011 Lawyer United States
Primary
Concomitant
Anxiety 2/10/2011 69 Female 9/6/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data