Methotrexate combined with Ms Contin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Mycosis Death 7/4/2005 Male 114 lb 1/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 61 Male 170 lb 2/27/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 3/9/2006
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Urticaria Hospitalization 8/30/2001 47 Male 187 lb 4/6/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Female 4/14/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/28/2003 31 Male 126 lb 4/24/2006
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 3/1/2006 Female 210 lb 5/3/2006 Physician United States
Primary
Concomitant
Bradycardia Hospitalization 6/12/2006 65 Male Pharmacist United States
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 6/30/2006 59 Male 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/8/2006 Other Health Professional United States
Primary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/14/2006 Other Health Professional United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/12/2006 Male 121 lb 9/18/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 75 Female 171 lb 12/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 75 Female 171 lb 11/29/2006 United Kingdom
Primary
Secondary
Concomitant
Facial Palsy Disability 1/1/2006 60 Female 12/8/2006 Consumer United States
Primary
Concomitant
Vision Blurred 1/1/2005 66 Female 200 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Muscular Weakness Hospitalization 42 Female 5/21/2007 Other Health Professional Australia
Primary
Concomitant
Mydriasis 5/1/2007 47 Female 101 lb 6/25/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/19/2005 Female 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 8/15/2007 Female 1/2/2008 Consumer United States
Primary
Concomitant
Temporomandibular Joint Syndrome Other Serious 1/1/2000 36 Female 1/18/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 1/22/2008 Physician United States
Primary
Concomitant
Rash Other Serious 8/15/2007 Female 114 lb 1/22/2008 Consumer United States
Primary
Concomitant
Lung Consolidation Hospitalization 3/1/2000 9 Male 49 lb 2/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 3/14/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 3/18/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 5/23/2008 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 6/16/2005 Female 225 lb 6/10/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2001 36 Female 157 lb 7/17/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 11/24/1999 36 Female 157 lb 7/23/2008 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/19/2005 Female 9/19/2008 Physician United States
Primary
Secondary
Concomitant
Carcinoma In Situ Of Skin Other Serious 9/15/2006 66 Female 165 lb 11/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 9/13/2008 Female 164 lb 11/26/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 9/13/2008 Male 12/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/13/2008 Female 164 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 10/1/2007 Female 114 lb 1/23/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/21/2009 Male 190 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 5/16/2009 Male 6/9/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Malignant Palate Neoplasm Other Serious 10/4/2007 66 Male 397 lb 7/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Malignant Palate Neoplasm Other Serious 10/4/2007 66 Male 397 lb 8/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Skin Discolouration Other Serious 7/5/2009 Female 251 lb 8/21/2009 Other Health Professional Canada
Primary
Concomitant
Malignant Palate Neoplasm Other Serious 10/4/2007 66 Male 397 lb 8/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal 5/1/2008 Female 250 lb 9/19/2009 United States
Primary
Concomitant
Death Hospitalization 43 Female 152 lb 9/28/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2009 63 Female 136 lb 9/23/2009 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2009 63 Female 136 lb 9/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Hospitalization Female 152 lb 10/23/2009 Physician United States
Primary
Concomitant
Ill-defined Disorder Hospitalization Female 11/2/2009 Canada
Primary
Concomitant
Carcinoma In Situ Of Skin Other Serious 1/9/2007 Female 148 lb 11/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Whipple's Disease Other Serious 4/1/2009 63 Female 136 lb 11/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Whipple's Disease Other Serious 4/1/2009 63 Female 136 lb 11/17/2009 United Kingdom
Primary
Secondary
Concomitant
Whipple's Disease Other Serious 4/1/2009 63 Female 62 lb 11/17/2009 United Kingdom
Primary
Secondary
Concomitant
Ill-defined Disorder Hospitalization Female 222 lb 11/25/2009 Canada
Primary
Concomitant
Surgery Hospitalization Female 222 lb 12/7/2009 Canada
Primary
Concomitant
Sepsis Death 10/15/2009 66 Male 240 lb 12/11/2009 Physician United States
Primary
Concomitant
Metastatic Squamous Cell Carcinoma Death 7/1/2009 Female 109 lb 12/28/2009 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 1/29/2007 Female 148 lb 12/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neoplasm Malignant Hospitalization Female 222 lb 12/29/2009 Canada
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 4/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 4/15/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 4/22/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/6/2010 United States
Primary
Secondary
Concomitant
Sciatica Other Serious 8/31/2009 53 Female 164 lb 5/10/2010 Consumer United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/17/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 6/8/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 6/18/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 6/24/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 7/19/2010 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/1/2010 66 Female 8/11/2010 Consumer
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/11/2010 63 Female 8/17/2010 Consumer Australia
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2009 40 Female 180 lb 9/10/2010 Consumer United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 10/4/2010 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/1/2010 66 Female 10/25/2010 Consumer
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2008 11/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Parathyroid Disorder Other Serious 7/1/2010 79 Female 96 lb 11/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Bladder Cancer Stage 0, With Cancer In Situ Other Serious 5/6/2008 11/28/2010 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2008 11/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vulvovaginal Candidiasis Other Serious 1/1/2010 48 Female 256 lb 12/17/2010 Consumer United States
Primary
Concomitant
Pyrexia 7/1/2010 62 Male 168 lb 11/6/2010 Consumer United States
Primary
Concomitant
Localised Infection Hospitalization 12/1/2009 77 Female 128 lb 1/28/2011 Physician United States
Primary
Concomitant
Stress Fracture Female 157 lb 1/28/2011 United States
Primary
Concomitant
Joint Swelling Male 190 lb 1/29/2011 Physician United States
Primary
Concomitant
Blister 7/11/2010 64 Female 1/29/2011 Consumer United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 12/27/2010 71 Female 2/1/2011 Consumer United States
Primary
Concomitant
Back Pain Hospitalization 1/1/2003 52 Male 2/14/2011 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 6/1/2010 3/15/2011 Physician United States
Primary
Concomitant
Bronchitis Other Serious 1/1/2003 52 Male 4/15/2011 Lawyer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2003 52 Male 4/25/2011 Other Health Professional United States
Primary
Concomitant
Stomatitis 4/20/2011 20 Female 188 lb 4/25/2011 United States
Primary
Secondary
Concomitant
Fatigue 1/1/2010 61 Male 2/7/2011 Consumer United States
Primary
Concomitant
Tenderness Hospitalization 4/22/2011 20 Female 188 lb 4/27/2011 Physician United States
Primary
Secondary
Concomitant
Candidiasis Hospitalization 4/1/2009 49 Male 128 lb 4/26/2011 United States
Primary
Secondary
Concomitant
Insomnia Death 1/1/2003 52 Male 5/19/2011 Physician United States
Primary
Concomitant
Anal Fistula Other Serious 2/1/2011 47 Male 5/27/2011 Consumer United States
Primary
Concomitant
Frequent Bowel Movements Male 170 lb 5/12/2011 Consumer United States
Primary
Concomitant
Pyrexia Male 170 lb 5/12/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2003 52 Male 6/17/2011 Lawyer United States
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2011 Female 117 lb 6/23/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Congestion Other Serious 6/2/2011 36 Female 174 lb 7/22/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Dialysis Hospitalization 5/1/2011 54 Male 274 lb 7/27/2011 Physician United States
Primary
Concomitant
Arthritis Hospitalization 1/1/1997 51 Female 157 lb 8/3/2011 Pharmacist United States
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 1/1/2003 57 Female 157 lb 8/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/1/2011 54 Male 274 lb 8/24/2011 Physician United States
Primary
Concomitant
Enthesopathy Hospitalization 1/1/2003 57 Female 157 lb 8/25/2011 Pharmacist United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 8/1/2010 73 Female 165 lb 8/26/2011 Physician United States
Primary
Concomitant
Ligament Rupture Hospitalization 12/28/2010 57 Female 8/23/2011 Physician Belgium
Primary
Concomitant
Spinal Osteoarthritis Other Serious 1/1/2003 57 Female 157 lb 9/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Volvulus Other Serious 9/9/2011 47 Male 201 lb 11/4/2011 Other Health Professional Canada
Primary
Concomitant
Dyspnoea Other Serious 10/1/2010 62 Female 251 lb 11/9/2011 Physician United States
Primary
Secondary
Concomitant
Hypotension Death 2/25/2011 67 Male 12/5/2011 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/8/2010 63 Female 134 lb 12/12/2011 Consumer Australia
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Other Serious 12/3/2010 48 Female 12/23/2011 Consumer Canada
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Other Serious 12/3/2010 48 Female 12/28/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/8/2010 63 Female 134 lb 12/29/2011 Consumer Australia
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 12/3/2010 48 Female 1/3/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Arteriosclerosis Hospitalization 6/1/2010 1/27/2012 Pharmacist United States
Primary
Concomitant
Haemorrhage 7/25/2011 56 Female 1/28/2012 Consumer United States
Primary
Concomitant
Pain In Extremity 3/1/2011 81 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 3/17/2011 50 Female 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 3/20/2011 55 Female 258 lb 1/28/2012 Consumer United States
Primary
Concomitant
Insomnia 5/4/2011 55 Female 252 lb 1/28/2012 Consumer United States
Primary
Concomitant
Drug Ineffective 3/20/2011 55 Female 1/28/2012 Consumer United States
Primary
Concomitant
Back Pain 9/15/2011 Female 250 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema 9/9/2011 48 Female 1/28/2012 Consumer United States
Primary
Secondary
Concomitant
Infection Other Serious 6/8/2010 63 Female 134 lb 2/6/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Dyspnoea Other Serious 6/2/2011 36 Female 174 lb 2/21/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Application Site Pruritus 2/1/2011 60 Male 195 lb 2/24/2012 Consumer United States
Primary
Concomitant
Dyspepsia Other Serious 5/1/2007 42 Female 2/27/2012 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 8/16/2010 70 Female 203 lb 3/23/2012 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma 8/16/2010 70 Female 203 lb 3/23/2012 Physician United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma 8/1/2010 73 Female 165 lb 3/30/2012 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma 8/16/2010 70 Female 203 lb 4/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 3/11/2012 31 Male 167 lb 4/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 4/25/2012 73 Female 5/24/2012 Other Health Professional Canada
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 12/1/2011 71 Female 7/5/2012 Other Health Professional Australia
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious Female 7/12/2012 Other Health Professional Australia
Primary
Concomitant
Mobility Decreased Hospitalization 1/1/2003 57 Female 157 lb 7/23/2012 Physician United States
Primary
Secondary
Concomitant
Post Laminectomy Syndrome Hospitalization 1/1/2003 57 Female 157 lb 8/27/2012 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/2003 Female 157 lb 11/29/2012 Consumer Us
Primary
Secondary
Concomitant
Nausea Other Serious 9/2012 Male 10/23/2012 Other Health Professional Au
Primary
Concomitant
Vomiting 5/7/2012 44 Female 143 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 12/19/2012 Consumer Us
Primary
Concomitant
Injection Site Pain 2011 63 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Arthralgia 1/3/2012 57 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Urinary Tract Infection Other Serious 2003 Female 10/10/2012 Consumer Us
Primary
Concomitant

Drug Data