Hydrochlorothiazide combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Basal Cell Carcinoma Other Serious 8/1/2005 Female 220 lb 1/3/2006 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 12/22/2005 Female 177 lb 1/12/2006 Other Health Professional United States
Primary
Concomitant
Death Death 12/25/2005 57 Male 235 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 9/28/2005 75 Female 115 lb 11/19/2005 Pharmacist United States
Primary
Concomitant
Breast Cancer Life Threatening Female 122 lb 1/17/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/4/2005 48 Female 1/17/2005 Australia
Primary
Secondary
Concomitant
Ankle Fracture Other Serious 8/1/2005 Female 281 lb 1/24/2006 Physician United States
Primary
Concomitant
Metastatic Neoplasm Life Threatening 10/11/2005 Female 1/24/2006 Physician Canada
Primary
Concomitant
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 1/25/2006 Physician Belgium
Primary
Secondary
Concomitant
Abdominal Abscess Hospitalization 11/8/2004 Female 148 lb 1/25/2006 Netherlands
Primary
Concomitant
Renal Failure Required Intervention 8/25/2005 61 Male 11/15/2005 Other Health Professional United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 9/15/2005 63 Male 304 lb 1/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 2/3/2006 Physician Belgium
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/15/2003 66 Male 190 lb 2/7/2006 Lawyer United States
Primary
Concomitant
Skin Ulcer Hospitalization 1/4/2005 57 Female 143 lb 2/8/2006 Germany
Primary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Tuberculosis Other Serious 11/1/2005 Male 245 lb 2/15/2006 Other Health Professional United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 12/22/2005 Female 185 lb 2/15/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Cavitation Other Serious 6/5/2003 Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2000 53 Female 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Renal Failure Death 12/25/2005 57 Male 235 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2005 Male 3/3/2006 Physician Canada
Primary
Concomitant
Pneumonia Death 2/1/2006 Male 289 lb 3/7/2006 Physician United States
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 3/6/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 10/29/2005 54 Male 21 lb 3/8/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 10/29/2005 54 Male 210 lb 3/8/2006 Other Health Professional United States
Primary
Concomitant
Tuberculin Test Positive Other Serious 11/8/2005 Male 245 lb 3/16/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 3/24/2006 Other Health Professional United States
Primary
Concomitant
Bone Neoplasm Malignant Other Serious 1/1/2006 Female 126 lb 3/31/2006 Other Health Professional United States
Primary
Concomitant
Nasal Septum Deviation Hospitalization 10/1/2002 52 Male 218 lb 4/5/2006 Lawyer United States
Primary
Concomitant
Uterine Cancer Other Serious 10/1/2004 Female 110 lb 4/7/2006 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 1/1/2000 78 Female 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/30/2003 77 Female 134 lb 4/11/2006 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/18/2005 68 Female 112 lb 11/4/2005 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2000 64 Female 291 lb 4/17/2006 Physician United States
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 Male 4/20/2006 Physician United States
Primary
Concomitant
Colitis Ischaemic Death 12/2/2005 Male 4/24/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2004 56 Female 176 lb 4/24/2006 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2002 65 Male 315 lb 4/24/2006 Lawyer United States
Primary
Concomitant
Breast Cancer Metastatic Other Serious 1/1/2006 Female 127 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Urinary Retention 57 Female 4/28/2006 Consumer United States
Primary
Secondary
Concomitant
Platelet Production Decreased Hospitalization 4/4/2006 60 Male 169 lb 4/27/2006 Pharmacist United States
Primary
Concomitant
Respiratory Distress Hospitalization 1/1/2000 78 Female 150 lb 5/3/2006 Physician United States
Primary
Concomitant
Uterine Leiomyoma Required Intervention 7/10/2000 62 Female 144 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 2/1/2002 65 Male 315 lb 5/11/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/31/2006 Female 225 lb 5/11/2006 Physician United States
Primary
Concomitant
Pneumonia Staphylococcal Other Serious 1/1/2006 Male 289 lb 5/11/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/24/2005 69 Female 135 lb 1/18/2006 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 12/1/2005 Female 201 lb 5/24/2006 Consumer Canada
Primary
Concomitant
Prostate Cancer Life Threatening 2/1/2004 70 Male 5/19/2006 United States
Primary
Concomitant
Cryptococcosis Hospitalization 11/3/2005 72 Male 195 lb 5/30/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Death 2/28/2006 68 Female 6/6/2006 Physician United States
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 5/1/2006 Female 215 lb 6/9/2006 Physician United States
Primary
Concomitant
Uterine Leiomyoma Required Intervention 7/10/2000 62 Female 144 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/1/2006 Female 130 lb 6/27/2006 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 6/30/2006 Other Health Professional United States
Primary
Concomitant
Diverticulitis Hospitalization 12/1/2005 Female 180 lb 7/10/2006 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 7/25/2005 Male 207 lb 7/12/2006 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 70 Male 7/7/2006
Primary
Concomitant
Ulcer Required Intervention 1/1/2004 38 Female 130 lb 6/30/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 12/14/2005 Female 201 lb 7/21/2006 Physician Canada
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 7/31/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Other Serious 9/10/2005 42 Female 144 lb 7/28/2006 Pharmacist United States
Primary
Concomitant
Gastritis Hospitalization 6/1/2006 Female 174 lb 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Malignant Anorectal Neoplasm Other Serious 7/11/2005 Female 8/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 7/13/2005 51 Female 8/7/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 79 Female 8/17/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/18/2006 Female 140 lb 8/28/2006 Other Health Professional United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 79 Female 8/18/2006
Primary
Concomitant
Sepsis Other Serious 10/16/2003 Female 121 lb 9/1/2006 Physician United States
Primary
Concomitant
Fracture Other Serious 7/25/2006 Female 114 lb 9/11/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 2/1/2006 Male 9/11/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 7/22/2006 Female 130 lb 9/13/2006 Consumer Canada
Primary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 9/15/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/26/2006 89 Female 9/18/2006 Physician Canada
Primary
Concomitant
Skin Reaction Other Serious 10/1/2006 Female 200 lb 10/4/2006 Physician United States
Primary
Concomitant
Sudden Death Other Serious 7/1/2006 67 Female 10/9/2006 Physician United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/18/2006 Female 140 lb 10/19/2006 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 150 lb 10/16/2006 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 9/1/2006 Female 11/8/2006 Physician
Primary
Concomitant
Compression Fracture Other Serious 7/25/2006 Female 114 lb 11/18/2006 Other Health Professional United States
Primary
Concomitant
Bladder Cancer Other Serious 11/1/2006 Female 182 lb 11/20/2006 Physician United States
Primary
Concomitant
Respiratory Arrest Death 2/1/2000 63 Male 11/21/2006 United States
Primary
Concomitant
Visual Disturbance Other Serious 9/1/2006 Female 147 lb 12/4/2006 Consumer United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 6/1/2006 Female 12/7/2006 Physician United States
Primary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 12/18/2006 Physician United States
Primary
Concomitant
Nerve Injury 7/15/2006 Female 180 lb 12/18/2006 Physician United States
Primary
Concomitant
Injection Site Bruising 9/12/2006 Female 291 lb 12/20/2006 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection 9/6/2006 75 Female 170 lb 12/22/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 3/1/2006 82 Female 12/28/2006 Consumer United States
Primary
Concomitant
Hodgkin's Disease Nodular Sclerosis Stage Iii Other Serious 7/28/2006 Female 108 lb 12/29/2006 Physician United States
Primary
Concomitant
Hepatitis Hospitalization 7/24/2002 74 Male 167 lb 10/7/2006 Physician United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 10/23/2006 57 Male 1/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/1/2005 63 Female 157 lb 11/28/2006 Physician United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 2/6/2006 Female 2/2/2007 Physician United States
Primary
Concomitant
Urine Odour Abnormal Other Serious 64 Female 150 lb 6/2/2006 United States
Primary
Concomitant
Vomiting Other Serious 10/16/2003 Female 121 lb 2/12/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 10/16/2003 Female 121 lb 2/16/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Plasma Cells Increased Other Serious 12/1/2006 74 Male 2/13/2007 Physician United States
Primary
Secondary
Concomitant
Plasma Cells Increased Other Serious 12/1/2006 74 Male 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Death 6/24/2004 62 Male 3/27/2007 Physician United States
Primary
Concomitant
Bursitis Hospitalization 8/20/2006 Female 190 lb 3/27/2007 Physician United States
Primary
Concomitant
Arthropathy Hospitalization Female 200 lb 3/28/2007 Consumer Canada
Primary
Concomitant
Histoplasmosis Other Serious 12/1/2006 Female 266 lb 4/2/2007 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 7/1/2006 Female 4/6/2007 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 7/6/2006 Female 147 lb 4/6/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 83 Male 4/9/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 7/6/2006 Female 147 lb 4/10/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 83 Male 225 lb 4/13/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2003 Female 165 lb 4/19/2007 Physician United States
Primary
Concomitant
Lupus-like Syndrome Other Serious 10/1/2006 51 Female 185 lb 4/27/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2005 82 Male 225 lb 5/7/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2005 82 Male 225 lb 5/9/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 5/3/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2005 82 Male 225 lb 5/14/2007 Pharmacist Norway
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2007 Female 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/30/2007 Female 263 lb 5/22/2007 Consumer Canada
Primary
Concomitant
Oedema Other Serious 12/1/2005 Female 187 lb 5/24/2007 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 4/30/2007 Female 263 lb 6/9/2007 Physician Canada
Primary
Concomitant
Influenza Like Illness Other Serious 4/8/2007 Female 195 lb 6/15/2007 Physician United States
Primary
Concomitant
Tendon Rupture Hospitalization 12/1/2002 Male 178 lb 6/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 5/14/2007 76 Female 6/15/2007 Canada
Primary
Concomitant
Drug Ineffective 3/19/2007 64 Female 150 lb 6/25/2007 Consumer United States
Primary
Concomitant
Postoperative Wound Infection Hospitalization 205 lb 6/25/2007 Consumer Canada
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 6/25/2007 United States
Primary
Concomitant
Prostate Cancer Other Serious Male 6/29/2007 Physician Portugal
Primary
Concomitant
Prostate Cancer Other Serious Male 129 lb 7/3/2007 Physician Portugal
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 7/6/2007 United States
Primary
Concomitant
Prostate Cancer Other Serious Male 129 lb 7/13/2007 Physician Portugal
Primary
Concomitant
Ureteric Obstruction Other Serious 10/1/2004 Female 7/13/2007 Physician United States
Primary
Concomitant
Rash Erythematous 7/12/2006 70 Female 7/26/2007 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/26/2007 Female 202 lb 7/27/2007 Physician United States
Primary
Concomitant
Lipomatosis Hospitalization 12/1/2004 64 Female 8/8/2007 Physician Germany
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 12/5/2004 70 Female 7/9/2007 Consumer United States
Primary
Concomitant
Leukoencephalomyelitis Other Serious Male 8/29/2007 Consumer United States
Primary
Secondary
Leukoencephalomyelitis Other Serious Male 8/29/2007 Consumer United States
Primary
Secondary
Tuberculosis Skin Test Positive Hospitalization 5/1/2006 Female 166 lb 9/14/2007 Physician United States
Primary
Concomitant
Death Death 9/10/2007 Female 9/19/2007 Consumer United States
Primary
Concomitant
Rash Other Serious 9/6/2007 Female 148 lb 9/12/2007 Other Health Professional United States
Primary
Concomitant
Herpes Zoster Hospitalization 8/29/2007 Female 9/20/2007 Physician United States
Primary
Concomitant
Anaemia Hospitalization 8/29/2007 47 Female 119 lb 9/28/2007 Physician United States
Primary
Concomitant

Drug Data