Cyclobenzaprine combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteomyelitis Hospitalization 10/1/2008 Female 194 lb 2/24/2009 Other Health Professional Canada
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/21/2009 53 Female 180 lb 2/25/2009 Other Health Professional Canada
Primary
Concomitant
Localised Infection 9/1/2008 Male 198 lb 3/14/2009 United States
Primary
Concomitant
Spondylolisthesis 1/1/2008 Female 155 lb 6/12/2009
Primary
Concomitant
Tooth Fracture 10/1/2008 Female 160 lb 6/12/2009 Consumer United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 11/1/2008 Female 160 lb 7/14/2009 United States
Primary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/15/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/21/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Mitral Valve Incompetence Other Serious 1/1/2007 Male 194 lb 8/21/2009 Brazil
Primary
Concomitant
Incorrect Dose Administered 6/5/2007 Female 9/11/2009 Pharmacist United States
Primary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Urinary Tract Infection 7/31/2009 Female 180 lb 9/19/2009 Physician
Primary
Secondary
Concomitant
Sleep Disorder 7/18/2005 54 Female 236 lb 9/23/2009 United States
Primary
Concomitant
Sinus Congestion 6/15/2009 12/9/2009 Physician United States
Primary
Concomitant
Histoplasmosis Other Serious 11/10/2009 Male 131 lb 12/14/2009 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2009 Female 146 lb 12/18/2009 Brazil
Primary
Concomitant
Thrombophlebitis Hospitalization 11/1/2008 Male 214 lb 12/23/2009 United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Life Threatening 10/13/2009 Male 181 lb 1/8/2010 United States
Primary
Concomitant
Vomiting 9/23/2009 Female 146 lb 1/29/2010 United States
Primary
Concomitant
Skin Discolouration 6/1/2009 Female 140 lb 1/30/2010 United States
Primary
Concomitant
Dyspepsia 6/1/2009 71 Female 203 lb 2/22/2010 Consumer United States
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Proctitis Hospitalization 8/1/2009 Male 150 lb 3/24/2010 Brazil
Primary
Concomitant
Skin Discolouration Other Serious 3/1/2010 56 Female 132 lb 4/16/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/5/2010 62 Female 4/20/2010 United States
Primary
Concomitant
H1n1 Influenza Other Serious 7/2/2009 53 Female 148 lb 5/13/2010 Other Health Professional Chile
Primary
Secondary
Concomitant
Breast Calcifications Other Serious 4/30/2010 54 Female 143 lb 5/18/2010 Physician Chile
Primary
Secondary
Concomitant
Breast Cancer Other Serious 4/30/2010 54 Female 143 lb 5/26/2010 Physician Chile
Primary
Secondary
Concomitant
Breast Calcifications Other Serious 5/7/2010 54 Female 143 lb 6/1/2010 Physician Chile
Primary
Secondary
Concomitant
Fibrocystic Breast Disease Other Serious 5/7/2010 54 Female 143 lb 6/8/2010 Physician Chile
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2009 44 Female 148 lb 7/2/2010 Consumer Brazil
Primary
Concomitant
Shock Life Threatening 9/13/2009 40 Female 7/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 52 Female 132 lb 7/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Lobar Pneumonia Hospitalization 4/5/2010 62 Female 7/8/2010 United States
Primary
Concomitant
Polyp Hospitalization 6/1/2010 55 Female 210 lb 7/22/2010 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2008 60 Female 142 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Breast Calcifications Other Serious 5/7/2010 54 Female 143 lb 8/10/2010 Physician Chile
Primary
Secondary
Concomitant
Throat Irritation Other Serious 7/1/2010 51 Female 188 lb 8/18/2010 Other Health Professional United States
Primary
Concomitant
Sinusitis 2/1/2010 51 Female 175 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Chest Discomfort Hospitalization 9/12/2010 53 Female 170 lb 9/23/2010 Other Health Professional Canada
Primary
Concomitant
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 9/1/2010 46 Female 180 lb 10/13/2010 Physician Canada
Primary
Concomitant
Hypophagia Death 1/1/2009 74 Female 133 lb 11/12/2010 Consumer United States
Primary
Concomitant
Hypophagia Death 1/1/2009 74 Female 133 lb 11/15/2010 Consumer United States
Primary
Concomitant
Sinusitis Female 175 lb 11/5/2010 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 10/21/2009 12/16/2010 Consumer Brazil
Primary
Concomitant
Pneumonia 12/18/2009 12/16/2010 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 6/1/2010 12/17/2010 Other Health Professional Brazil
Primary
Concomitant
Injection Site Swelling 2/15/2010 12/19/2010 Consumer United States
Primary
Concomitant
Skin Discolouration 5/1/2010 50 Female 155 lb 11/6/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Haematoma 12/23/2010 Consumer United States
Primary
Concomitant
Wheezing 8/30/2010 12/23/2010 Consumer United States
Primary
Concomitant
Injection Site Warmth 7/1/2010 12/23/2010 Consumer United States
Primary
Concomitant
Wheezing 9/20/2010 12/23/2010 Consumer United States
Primary
Concomitant
Wheezing 9/1/2010 12/23/2010 Consumer United States
Primary
Concomitant
Dizziness 10/16/2010 12/23/2010 Consumer United States
Primary
Concomitant
Exostosis Hospitalization 9/15/2010 50 Male 175 lb 12/27/2010 Consumer United States
Primary
Concomitant
Injection Site Pruritus 10/19/2010 12/28/2010 Consumer United States
Primary
Concomitant
Hydronephrosis Other Serious 5/30/1996 48 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Feeling Hot 1/9/2010 44 Female 142 lb 1/28/2011 Consumer United States
Primary
Concomitant
Bronchitis Hospitalization Male 240 lb 1/28/2011 Consumer United States
Primary
Concomitant
Arthralgia 2/1/2010 47 Female 108 lb 1/28/2011 United States
Primary
Concomitant
Lymphadenopathy 4/12/2010 63 Female 191 lb 1/29/2011 Physician United States
Primary
Concomitant
Incorrect Dose Administered 2/1/2010 Female 1/29/2011 Consumer United States
Primary
Concomitant
Balance Disorder 5/7/2010 58 Female 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 9/13/2010 53 Female 1/30/2011 Consumer United States
Primary
Concomitant
H1n1 Influenza Other Serious 7/2/2009 53 Female 148 lb 2/4/2011 Other Health Professional Chile
Primary
Secondary
Concomitant
Fibrocystic Breast Disease Other Serious 4/30/2010 54 Female 143 lb 2/7/2011 Physician Chile
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1/1/2010 63 Female 176 lb 2/9/2011 Consumer United Kingdom
Primary
Concomitant
Renal Atrophy Other Serious 5/30/1996 48 Female 2/10/2011 United States
Primary
Secondary
Concomitant
Lymphoma Other Serious 8/1/2010 57 Female 121 lb 2/10/2011 Consumer Brazil
Primary
Concomitant
Anxiety Other Serious 5/30/1996 48 Female 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Lymphoma Other Serious 10/18/2010 57 Female 121 lb 2/23/2011 Consumer Brazil
Primary
Concomitant
Musculoskeletal Pain Hospitalization 1/1/2010 63 Female 176 lb 3/4/2011 Consumer United Kingdom
Primary
Concomitant
Opportunistic Infection Other Serious 10/17/2010 28 Female 249 lb 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Mesangioproliferative Glomerulonephritis Hospitalization 1/1/2009 48 Female 254 lb 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Application Site Pruritus 8/1/2009 58 Female 3/25/2011 Consumer United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Fungal Death 1/9/2011 28 Female 249 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/1/2010 53 Female 161 lb 4/15/2011 Consumer Brazil
Primary
Concomitant
Epistaxis Other Serious 1/15/2011 66 Female 207 lb 5/3/2011 Other Health Professional Canada
Primary
Concomitant
Osteoporosis Other Serious 1/1/2004 52 Female 132 lb 5/5/2011 Consumer Brazil
Primary
Secondary
Concomitant
Arthralgia Other Serious 5/1/2010 58 Female 247 lb 5/12/2011 Consumer Brazil
Primary
Concomitant
Blood Pressure Increased Other Serious 1/1/2010 51 Male 325 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2010 63 Female 176 lb 5/17/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Cholecystectomy Other Serious 1/1/2007 26 Female 216 lb 5/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Injection Site Swelling 4/20/2010 58 Female 170 lb 5/17/2011 Consumer United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 5/20/2011 62 Female 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 5/20/2011 62 Female 134 lb 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Gingival Swelling 1/1/2010 55 Female 175 lb 5/11/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 1/1/2010 63 Female 176 lb 6/15/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Perforation Life Threatening Female 143 lb 6/21/2011 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization 5/20/2011 62 Female 134 lb 6/23/2011 Physician United States
Primary
Secondary
Concomitant
Bile Duct Cancer Hospitalization 5/20/2011 62 Female 134 lb 6/24/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 5/20/2011 62 Female 6/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystectomy Other Serious Female 230 lb 6/20/2011 Lawyer United States
Primary
Concomitant
Blister 4/21/2011 61 Female 158 lb 7/5/2011 Consumer United States
Primary
Concomitant
Bile Duct Cancer Hospitalization 5/20/2011 62 Female 134 lb 7/28/2011 Physician United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 5/1/2011 32 Male 130 lb 7/18/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/5/2010 62 Female 8/19/2011 Physician United States
Primary
Concomitant
Biliary Dyskinesia Other Serious 1/1/2007 26 Female 216 lb 8/19/2011 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/1/2009 61 Female 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 8/22/2011 50 Female 226 lb 8/30/2011 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 8/22/2011 50 Female 226 lb 9/6/2011 Physician United States
Primary
Secondary
Concomitant
Iatrogenic Injury Other Serious 6/4/2010 45 Female 246 lb 10/4/2011 Physician United States
Primary
Secondary
Concomitant
Bladder Operation Hospitalization 9/20/2011 43 Female 10/17/2011 Other Health Professional Canada
Primary
Concomitant
Accident At Home Other Serious 8/31/2011 66 Female 198 lb 10/18/2011 Other Health Professional Canada
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/13/2011 58 Female 255 lb 10/18/2011 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 10/1/2010 62 Female 251 lb 11/9/2011 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Tract Irritation Other Serious 11/4/2004 39 Female 246 lb 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 9/1/2010 46 Female 180 lb 11/18/2011 Physician Canada
Primary
Concomitant
Hallucination Hospitalization Female 11/23/2011 Consumer United States
Primary
Secondary
Concomitant
Arthralgia Other Serious 11/1/2010 53 Female 161 lb 12/14/2011 Consumer Brazil
Primary
Concomitant
Ovarian Cyst Hospitalization 1/1/2010 38 Female 106 lb 12/20/2011 Consumer Brazil
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 11/1/2009 61 Female 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Chondropathy Hospitalization 8/1/2011 51 Female 176 lb 1/5/2012 Consumer United States
Primary
Concomitant
Sjogren's Syndrome Other Serious 12/1/2011 67 Female 203 lb 1/12/2012 Other Health Professional Canada
Primary
Concomitant
Pain Hospitalization 36 Female 165 lb 1/13/2012 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 5/1/2011 32 Male 130 lb 1/10/2012 Consumer United States
Primary
Concomitant
Cough 12/1/2010 59 Female 152 lb 1/27/2012 Consumer United States
Primary
Concomitant
Sinusitis 4/8/2011 61 Female 1/28/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral 7/1/2011 61 Female 1/28/2012 Consumer United States
Primary
Concomitant
Bronchitis 1/26/2011 56 Female 1/27/2012 Consumer United States
Primary
Concomitant
Hypoaesthesia 3/1/2011 67 Female 1/28/2012 Consumer United States
Primary
Secondary
Concomitant
Sensory Disturbance 3/26/2011 48 Female 1/28/2012 Consumer United States
Primary
Concomitant
Hot Flush 3/1/2011 45 Female 238 lb 1/28/2012 Consumer United States
Primary
Concomitant
Joint Swelling Female 1/28/2012 Physician United States
Primary
Concomitant
Injection Site Pain 10/12/2011 46 Female 1/28/2012 Consumer United States
Primary
Concomitant
Rash Papular 11/1/2011 66 Female 1/29/2012 Consumer United States
Primary
Concomitant
Blood Pressure Fluctuation Hospitalization 12/1/2003 65 Female 142 lb 1/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage 1/1/2010 72 Female 1/28/2012 Consumer United States
Primary
Concomitant
Nasopharyngitis 10/1/2011 41 Female 1/28/2012 Consumer United States
Primary
Concomitant
Vitamin D Decreased Other Serious 1/1/2001 54 Female 175 lb 1/31/2012 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 9/1/2011 53 Male 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Papule 8/1/2011 46 Female 1/28/2012 Consumer United States
Primary
Concomitant
Rash Papular 1/1/2011 41 Female 260 lb 1/28/2012 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/28/2011 60 Male 300 lb 1/28/2012 Consumer United States
Primary
Concomitant
Arthralgia Disability 5/1/2010 58 Female 247 lb 2/3/2012 Consumer Brazil
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2003 65 Female 142 lb 2/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Ankle Fracture Other Serious 3/1/2011 67 Female 130 lb 2/28/2012 Consumer United States
Primary
Concomitant
Musculoskeletal Pain Other Serious 1/1/2010 48 Female 3/9/2012 Consumer Brazil
Primary
Concomitant
Arrhythmia Supraventricular Hospitalization 12/1/2003 65 Female 142 lb 4/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2012 34 Female 159 lb 4/24/2012 Consumer Brazil
Primary
Concomitant
Injection Site Pain Other Serious 1/1/2010 48 Female 5/7/2012 Consumer Brazil
Primary
Concomitant
Sinus Disorder Other Serious 1/1/2011 51 Female 162 lb 5/18/2012 Consumer United States
Primary
Concomitant
Joint Injury Other Serious 3/20/2012 52 Female 181 lb 5/21/2012 Consumer Brazil
Primary
Concomitant
Endometriosis Hospitalization 5/14/2012 47 Female 154 lb 6/1/2012 Physician Canada
Primary
Concomitant
Cystitis Noninfective Female 6/5/2012 Physician United States
Primary
Concomitant
Hyperglycaemia Hospitalization 12/1/2003 65 Female 142 lb 6/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/21/2012 43 Female 141 lb 6/6/2012 Consumer Brazil
Primary
Concomitant

Drug Data