Ganciclovir combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Spinal Myelogram Abnormal Other Serious 34 Female 3/21/2006 Physician Japan
Primary
Concomitant
Granulocytopenia Required Intervention 59 Male 5/11/2006 Other Health Professional United States
Primary
Concomitant
Human Herpesvirus 6 Infection Death 34 Male 5/23/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Required Intervention 55 Female 10/5/2006 Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8 Male 1/16/2007 Other Health Professional Germany
Primary
Concomitant
Postrenal Failure Other Serious 35 Male 2/27/2007 Japan
Primary
Concomitant
Postrenal Failure Other Serious 35 Male 2/27/2007 Japan
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 48 Male 3/3/2007 Japan
Primary
Concomitant
Pneumonia Cytomegaloviral Other Serious 15 Female 2/27/2007 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 48 Male 3/10/2007 Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 54 Male 4/18/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/2006 54 Male 157 lb 6/12/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/2006 54 Male 157 lb 7/24/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/5/2007 Switzerland
Primary
Secondary
Concomitant
Shock Hospitalization 11/19/2007 Female 37 lb 1/28/2008 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/22/2005 31 Female 1/15/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 6/22/2005 31 Female 2/1/2008 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious Female 3/4/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/14/2007 40 Female 4/2/2008 Japan
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 9/29/2006 51 Female 98 lb 4/7/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/29/2006 51 Female 98 lb 4/17/2008 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 9/5/2006 6 Female 4/18/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 35 Female 5/22/2008
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2007 52 Male 7/16/2008 Japan
Primary
Concomitant
Viral Dna Test Positive Death 3/14/2007 36 Female 7/28/2008 Physician Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 8/12/2008 Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Stomatitis Other Serious 8/21/2008 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/25/2007 48 Female 9/4/2008 Japan
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 9/25/2007 48 Female 9/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Visual Impairment Other Serious 4/21/2008 Male 36 lb 11/4/2008 Pharmacist Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Systemic Candida Death 45 Male 12/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 1/17/2008 9 Male 88 lb 12/26/2008 Physician Japan
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 47 Male 2/10/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Leukoencephalopathy Death Female 2/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 3/20/2009 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Death 1/1/2008 64 Female 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thirst Other Serious 12/25/2007 49 Female 123 lb 4/3/2009 Physician Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 69 Female 5/29/2009
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2008 7 Female 7/13/2009 Other Health Professional Japan
Primary
Concomitant
Pneumonia Cytomegaloviral Other Serious 57 Male 10/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2008 7 Female 10/15/2009 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 58 Male 10/27/2009 Physician Japan
Primary
Concomitant
Oesophageal Carcinoma Other Serious 27 Male 11/25/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/1/2006 65 Male 12/7/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 65 Male 12/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/30/2009 15 Male 12/8/2009 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Other Serious 11/1/2003 52 Male 1/25/2010
Primary
Secondary
Stem Cell Transplant Hospitalization 6/30/2009 15 Male 2/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 6/30/2009 15 Male 2/18/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Other Serious 60 Male 2/26/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 70 Male 2/26/2010 Physician Japan
Primary
Concomitant
Pneumatosis Intestinalis Other Serious 60 Male 3/12/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 40 Male 3/22/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Respiratory Failure Hospitalization 12/16/2008 73 Male 117 lb 3/24/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 6/30/2009 15 Male 88 lb 4/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/30/2009 15 Male 88 lb 4/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/16/2008 73 Male 117 lb 4/13/2010 Physician Japan
Primary
Concomitant
Superinfection Fungal Hospitalization 57 Female 5/3/2010 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/24/2009 15 Male 88 lb 5/3/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 1/16/2008 4 Male 38 lb 5/26/2010 Physician Japan
Primary
Concomitant
Visual Impairment Disability 3/11/2009 48 Female 84 lb 4/29/2010 Physician Japan
Primary
Concomitant
Stem Cell Transplant Other Serious 3/11/2009 48 Female 84 lb 7/19/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Transplant Failure Other Serious 13 Male 8/18/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Haematological Malignancy Other Serious NotSpecified 8/20/2010 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 12/10/2009 5 Male 53 lb 9/1/2010 Physician Japan
Primary
Concomitant
Serotonin Syndrome Hospitalization 8/23/2010 23 Female 121 lb 9/6/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 8/23/2010 23 Female 121 lb 9/24/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Sepsis Other Serious 7/22/2010 14 Female 97 lb 10/22/2010 Physician Japan
Primary
Concomitant
Retinal Artery Occlusion Other Serious 73 Female 10/22/2010 Physician Thailand
Primary
Concomitant
Encephalitis Fungal Death Male 139 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 7/17/2009 28 Male 110 lb 11/23/2010 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 48 Female 84 lb 11/8/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Death 1/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/13/2010 58 Male 121 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Death 8/6/2010 67 Female 110 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Glossitis Hospitalization 9/13/2010 58 Male 121 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/22/2010 14 Female 97 lb 2/14/2011 Physician Japan
Primary
Concomitant
Candida Test Positive Other Serious 61 Male 2/23/2011 Physician Japan
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 46 Male 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Other Serious 58 Female 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Other Serious 36 Male 3/12/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Memory Impairment Death 59 Male 3/23/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2007 57 Female 82 lb 4/7/2011 Physician Japan
Primary
Secondary
Concomitant
Delirium Other Serious 6/16/2010 53 Male 154 lb 4/8/2011 Physician Japan
Primary
Concomitant
Pseudomonas Infection Hospitalization 8/4/2006 48 Male 165 lb 4/12/2011 Physician Japan
Primary
Concomitant
Hepatitis Fulminant Other Serious 58 Female 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Mucous Membrane Disorder Disability 8/1/2009 20 Male 110 lb 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 9/4/2010 Male 33 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/13/2010 58 Male 121 lb 4/25/2011 Physician Japan
Primary
Secondary
Concomitant
Nocardiosis Other Serious 48 Male 6/6/2011 Other Health Professional Japan
Primary
Concomitant
Transplant Failure Other Serious 10/26/2009 52 Male 121 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Mycosis Other Serious 3/2/2010 63 Male 130 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 12/20/2003 27 Female 108 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 12/10/2003 27 Female 108 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Mucous Membrane Disorder Disability 8/1/2009 20 Male 110 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 17 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 43 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 32 Female 7/14/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 38 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 18 Male 7/14/2011 Physician China
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 32 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Engraft Failure Other Serious 6/9/2010 10 Female 88 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/9/2010 10 Female 88 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Death 12/10/2009 7 Male 53 lb 7/19/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 12/10/2003 27 Female 108 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 15 Male 8/3/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Disability 6/6/2011 13 Female 88 lb 9/20/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 1/1/2007 57 Female 9/21/2011 Physician Germany
Primary
Concomitant
Renal Failure Life Threatening 5/16/2011 8 Female 49 lb 9/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 72 Female 9/30/2011 Physician Japan
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 5/22/2011 8 Female 49 lb 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Periorbital Oedema Life Threatening 1/27/2011 6 Female 40 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 12/7/2010 6 Female 40 lb 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 6/12/2010 53 Male 154 lb 10/5/2011 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 72 Female 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 6 Female 40 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Other Serious 6/9/2010 10 Female 88 lb 10/12/2011 Physician Japan
Primary
Secondary
Concomitant
Engraft Failure Death 6/9/2010 10 Female 88 lb 10/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 72 Female 10/13/2011 Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 10/24/2004 17 Male 10/24/2011 Physician China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 43 Male 10/24/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 1/8/2008 32 Female 10/24/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 11/29/2006 38 Male 10/24/2011 Physician China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/16/2009 32 Male 10/25/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 4/21/2008 18 Male 10/25/2011 Other Health Professional China
Primary
Concomitant
Visual Impairment Death 6/6/2011 13 Female 88 lb 11/8/2011 Physician Japan
Primary
Concomitant
Neutropenic Sepsis Other Serious 26 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Death 41 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 54 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 22 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 49 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Death 51 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 5/12/2011 6 Female 31 lb 11/22/2011 Physician Japan
Primary
Concomitant

Drug Data