Endoxan combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Distress Hospitalization 12/9/2005 72 Male 163 lb 1/13/2006 Consumer United States
Primary
Secondary
Concomitant
Deafness Hospitalization 12/2/2005 57 Female 1/18/2006 Consumer United States
Primary
Secondary
Thrombocytopenia Hospitalization 11/12/2004 61 Male 181 lb 1/18/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Life Threatening 10/15/2005 66 Female 1/18/2006 Consumer United States
Primary
Secondary
Concomitant
Dermatomyositis Hospitalization 3/15/2005 54 Female 2/16/2006 Physician France
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 3/15/2005 54 Female 2/22/2006
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/1/2005 76 Male 3/18/2006 Pharmacist Japan
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 Male 168 lb 3/28/2006 Physician Germany
Primary
Concomitant
Treatment Related Secondary Malignancy Death 3/1/2005 42 Female 3/28/2006 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 2/8/2006 68 Female 126 lb 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
Chronic Eosinophilic Leukaemia Hospitalization 12/1/2000 43 Male 5/5/2006 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 6/8/2002 63 Female 5/5/2006 Other Health Professional France
Primary
Secondary
Hepatitis Acute Hospitalization 2/24/2006 31 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/4/2006 40 Female 209 lb 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/1/2005 0 Male 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Chronic Eosinophilic Leukaemia Hospitalization 12/1/2000 43 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 40 Female 5/19/2006 Consumer Japan
Primary
Secondary
Concomitant
Nephropathy Hospitalization 2/1/2001 54 Male 176 lb 6/1/2006 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/1/2005 0 Male 6/5/2006 Consumer United States
Primary
Secondary
Concomitant
Nephropathy Hospitalization 2/1/2001 54 Male 176 lb 6/6/2006 Consumer United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 5/10/2006 49 Female 212 lb 6/29/2006 Other Health Professional France
Primary
Secondary
Venoocclusive Liver Disease Other Serious 2/1/2005 0 Male 7/3/2006 Consumer United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 5/10/2006 49 Female 212 lb 7/19/2006 Other Health Professional France
Primary
Secondary
Renal Disorder Other Serious 1/1/2002 16 Female 95 lb 7/21/2006 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 1/1/2001 56 Male 7/25/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 5/5/2005 20 Male 8/3/2006 Consumer United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/9/2004 68 Female 8/11/2006 Consumer United States
Primary
Secondary
Dysgeusia Other Serious Female 8/14/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 5/5/2005 20 Male 8/30/2006 Consumer United States
Primary
Secondary
Concomitant
Oral Mucosal Disorder Hospitalization 2/9/2006 10 Male 8/30/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2003 26 Female 121 lb 10/20/2006 Lawyer France
Primary
Secondary
Vomiting Hospitalization 10/17/2006 61 Female 11/2/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/4/2002 56 Female 11/20/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 11/29/2006 Consumer France
Primary
Secondary
Concomitant
Petechiae Hospitalization 6/8/2002 63 Female 12/5/2006 Other Health Professional France
Primary
Secondary
Mucosal Inflammation Hospitalization 11/17/2006 63 Female 12/11/2006 Consumer United States
Primary
Secondary
Vomiting Hospitalization 12/23/2002 7 Female 35 lb 12/18/2006 Pharmacist France
Primary
Concomitant
Interstitial Lung Disease Hospitalization 12/1/2006 73 Female 12/20/2006 Consumer United States
Primary
Secondary
Thrombocytopenia Hospitalization 8/1/2006 60 Female 121 lb 12/22/2006 Consumer France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/1/2006 60 Female 121 lb 1/2/2007 Consumer France
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 11/24/2006 73 Female 1/8/2007 Consumer United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Hospitalization 16 Male 1/23/2007 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 10/1/2003 26 Female 121 lb 1/29/2007 Lawyer France
Primary
Secondary
Febrile Neutropenia Hospitalization 10/10/2006 75 Male 1/30/2007 Consumer United States
Primary
Secondary
Concomitant
Tendonitis Other Serious 3/14/2006 49 Male 165 lb 2/7/2007 Physician
Primary
Concomitant
Interstitial Lung Disease Hospitalization Female 2/14/2007 Consumer United States
Primary
Secondary
Interstitial Lung Disease Life Threatening 6/24/2004 31 Female 2/21/2007 Consumer Japan
Primary
Secondary
Logorrhoea Hospitalization 12/21/2006 61 Female 2/23/2007 Consumer United States
Primary
Secondary
Skin Disorder Other Serious 62 Female 110 lb 3/2/2007 Other Health Professional United States
Primary
Secondary
Interstitial Lung Disease Life Threatening 6/24/2004 31 Female 3/5/2007 Consumer Japan
Primary
Secondary
Logorrhoea Hospitalization 12/21/2006 61 Female 3/5/2007 Consumer United States
Primary
Secondary
Leukoencephalopathy Other Serious 4/8/2001 2 Female 3/9/2007 Consumer United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 5/13/2005 63 Female 3/13/2007 Consumer United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/13/2007 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/13/2007 Other Health Professional United States
Primary
Secondary
Malignant Neoplasm Progression Other Serious 5/13/2005 63 Female 3/16/2007 Consumer United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/23/2006 64 Male 3/19/2007 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 1/23/2006 64 Male 3/23/2007 Consumer Japan
Primary
Secondary
Pyrexia Other Serious 12/23/2006 Female 163 lb 4/4/2007 Physician Bahrain
Primary
Concomitant
Tendonitis Other Serious 3/14/2006 49 Male 165 lb 4/19/2007 Physician
Primary
Concomitant
Tongue Coated Hospitalization 2/1/2007 65 Male 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/11/2006 10 Female 68 lb 5/1/2007 Consumer United States
Primary
Secondary
Status Epilepticus Life Threatening 3/22/2007 42 Male 5/3/2007 Consumer United States
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 3/22/2007 Male 5/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 1/1/2007 38 Female 117 lb 5/14/2007 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/11/2006 10 Female 68 lb 5/16/2007 Consumer United States
Primary
Secondary
Tongue Coated Hospitalization 2/1/2007 65 Male 5/17/2007 Consumer Japan
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening Male 5/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 21 Male 5/22/2007 Other Health Professional Japan
Primary
Secondary
Methaemoglobinaemia Life Threatening 4/26/2007 Female 141 lb 6/13/2007 Other Health Professional France
Primary
Concomitant
Pyrexia Other Serious 35 Male 6/19/2007 Japan
Primary
Secondary
Pyrexia Hospitalization 5/9/2006 57 Male 6/19/2007 Consumer Japan
Primary
Secondary
Viral Dna Test Positive Other Serious 46 Male 6/24/2007 Japan
Primary
Secondary
Tumour Lysis Syndrome Other Serious 21 Male 6/25/2007 Consumer United States
Primary
Secondary
Pleural Fibrosis Disability 2/1/1994 29 Male 79 lb 6/29/2007 Consumer United States
Primary
Secondary
Concomitant
Mucoepidermoid Carcinoma Other Serious 1/20/2006 24 Female 8/3/2007 Consumer United States
Primary
Secondary
Pleural Effusion Life Threatening 1/1/2007 38 Female 117 lb 8/10/2007 Physician France
Primary
Concomitant
Death Life Threatening 50 Male 8/30/2007 Consumer United States
Primary
Secondary
Concomitant
Hepatitis B Death 3/1/2006 54 Male 9/11/2007 Japan
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 7/16/2007 56 Female 9/13/2007 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 2/1/2006 54 Male 9/18/2007 Japan
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 7/16/2007 56 Female 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Disability 6/1/2007 49 Male 187 lb 9/27/2007 Pharmacist France
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2004 53 Female 9/29/2007 France
Primary
Secondary
Concomitant
Urinary Retention Disability 6/1/2007 49 Male 187 lb 10/2/2007 Pharmacist France
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 2/1/2006 54 Male 10/2/2007 Japan
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 1/1/2007 38 Female 117 lb 10/11/2007 Physician France
Primary
Concomitant
Myocarditis Mycotic Other Serious 57 Male 10/13/2007 Japan
Primary
Concomitant
Stem Cell Transplant Other Serious 7/3/2003 1 Male 19 lb 10/17/2007 Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 6/29/2006 2 Male 10/18/2007 Consumer United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 57 Male 10/24/2007 Japan
Primary
Concomitant
Pneumonia Death 1/13/2007 28 Female 10/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 9/2/2007 28 Female 10/30/2007 Consumer United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 9/19/2007 50 Female 10/31/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2007 28 Female 11/5/2007 Consumer United States
Primary
Secondary
Febrile Neutropenia Other Serious 28 Female 11/9/2007 Japan
Primary
Concomitant
Sepsis Other Serious 70 Female 11/13/2007 Consumer United States
Primary
Secondary
Concomitant
Cardiac Tamponade Life Threatening 9/27/2007 50 Female 11/14/2007 Consumer United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/22/2007 57 Male 11/16/2007 Consumer United States
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 5/18/2007 62 Male 11/16/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 70 Female 11/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 5/27/2007 Male 12/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 1/3/2007 61 Female 12/27/2007 Consumer United States
Primary
Secondary
Vomiting Other Serious 6/27/2007 51 Female 1/7/2008 Consumer France
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/27/2007 51 Female 1/10/2008 Consumer France
Primary
Secondary
Concomitant
Hairy Cell Leukaemia Other Serious 3/1/2007 75 Female 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2007 69 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 33 Female 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/20/2007 35 Female 1/24/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 33 Female 2/5/2008 Consumer United States
Primary
Secondary
Concomitant
Wheezing Death 1/19/2008 49 Male 154 lb 2/8/2008 Physician France
Primary
Secondary
Somnolence Death 12/19/2007 Male 176 lb 2/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 2/11/2008 Consumer United States
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Other Serious 56 Male 3/4/2008 Japan
Primary
Secondary
Concomitant
Pemphigoid Other Serious Female 3/10/2008 Japan
Primary
Concomitant
Chronic Granulomatous Disease Hospitalization Female 3/9/2008 Japan
Primary
Secondary
Concomitant
Rash Other Serious 56 Male 3/9/2008 Japan
Primary
Secondary
Concomitant
Rash Other Serious 12/1/2006 56 Male 3/11/2008 Japan
Primary
Secondary
Concomitant
Oedema Mucosal Hospitalization 27 Female 3/12/2008 Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 3/17/2008 Japan
Primary
Concomitant
Venous Occlusion Life Threatening 5 Female 3/18/2008 Consumer United States
Primary
Secondary
Venous Occlusion Life Threatening 5 Female 3/24/2008 Consumer United States
Primary
Secondary
Respiratory Failure Other Serious 12/27/2007 58 Male 3/28/2008 Physician France
Primary
Secondary
Concomitant
Wheezing Death 1/19/2008 49 Male 154 lb 3/29/2008 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 4/3/2008 Consumer United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 1/21/2008 Male 5/5/2008 Physician France
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 12 Male 5/12/2008 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/5/2008 58 Female 5/28/2008 Consumer United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 4/20/2008 28 Female 6/3/2008 Consumer United States
Primary
Secondary
Concomitant
Gastric Haemorrhage Other Serious 8/30/2006 63 Male 6/10/2008 Consumer United States
Primary
Secondary
Gastric Perforation Other Serious 11/23/2005 46 Male 6/10/2008 Consumer United States
Primary
Secondary
Febrile Bone Marrow Aplasia Other Serious 6/18/2005 53 Male 6/10/2008 Consumer United States
Primary
Secondary
Toxic Skin Eruption Hospitalization 5/1/2008 14 Male 143 lb 6/19/2008 Consumer United States
Primary
Secondary
Concomitant
Mucoepidermoid Carcinoma Other Serious 1/20/2006 24 Female 6/24/2008 Consumer United States
Primary
Secondary
Stomatitis Other Serious Female 6/26/2008 Other Health Professional France
Primary
Secondary
Breast Cancer Other Serious 1/1/2004 24 Female 7/28/2008 Consumer United States
Primary
Secondary
X-ray Dental Other Serious 12/28/2007 Female 7/31/2008 Other Health Professional France
Primary
Concomitant
Stomatitis Other Serious 5/5/2008 58 Female 9/10/2008 Consumer United States
Primary
Secondary
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/1/2008 14 Male 143 lb 9/26/2008 Consumer United States
Primary
Secondary
Concomitant
Cerebral Thrombosis Hospitalization 9/6/2008 Male 172 lb 10/16/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2007 20 Male 10/24/2008 Physician Japan
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2007 20 Male 10/24/2008 Physician Japan
Primary
Secondary
Burkitt's Lymphoma Hospitalization 1/1/2008 66 Male 11/5/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 7/10/2008 Female 99 lb 11/6/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pupils Unequal Hospitalization 12/1/2007 7 Male 11/10/2008 Consumer France
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 10/19/2008 Male 11/13/2008 Consumer United Kingdom
Primary
Secondary
Rash Morbilliform Hospitalization 9/20/2008 Female 31 lb 11/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pupils Unequal Hospitalization 12/1/2007 7 Male 12/1/2008 Other Health Professional France
Primary
Secondary
Concomitant

Drug Data