Mabthera combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Deafness Hospitalization 12/2/2005 57 Female 1/18/2006 Consumer United States
Primary
Secondary
Thrombocytopenia Hospitalization 11/12/2004 61 Male 181 lb 1/18/2006 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 2/24/2006 31 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/4/2006 40 Female 209 lb 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 40 Female 5/19/2006 Consumer Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 5/10/2006 49 Female 212 lb 6/29/2006 Other Health Professional France
Primary
Secondary
Cerebral Haemorrhage Hospitalization 5/10/2006 49 Female 212 lb 7/19/2006 Other Health Professional France
Primary
Secondary
Septic Shock Life Threatening 8/29/2006 50 Male 9/18/2006 Physician Israel
Primary
Concomitant
Amyotrophic Lateral Sclerosis Other Serious 3/1/2006 47 Male 150 lb 11/14/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Amyotrophic Lateral Sclerosis Other Serious 3/1/2006 47 Male 150 lb 11/20/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Amyotrophic Lateral Sclerosis Disability 3/1/2006 47 Male 11/23/2006 Switzerland
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/17/2006 63 Female 12/11/2006 Consumer United States
Primary
Secondary
Febrile Neutropenia Hospitalization 10/10/2006 75 Male 1/30/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/12/2006 51 Male 166 lb 2/20/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Monoparesis Hospitalization 11/1/2006 65 Male 4/9/2007 Physician United Kingdom
Primary
Concomitant
Tinnitus Other Serious 80 Female 4/13/2007 Consumer United Kingdom
Primary
Concomitant
Tinnitus Other Serious 80 Female 4/19/2007 Consumer United Kingdom
Primary
Concomitant
Sepsis Death Female 128 lb 4/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 3/22/2007 42 Male 5/3/2007 Consumer United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2007 Female 5/4/2007 Physician United Kingdom
Primary
Concomitant
Status Epilepticus Life Threatening 3/22/2007 Male 5/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Superinfection Death Male 5/9/2007 Physician Netherlands
Primary
Concomitant
Pulmonary Fibrosis Hospitalization Female 5/10/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Gastroenteritis Other Serious 4/8/2007 Male 5/10/2007 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 71 Female 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2007 Male 5/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Neoplasm Skin Hospitalization 2/28/2006 55 Female 5/17/2007
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/20/2007 Female 132 lb 5/18/2007 Consumer United Kingdom
Primary
Concomitant
Malignant Melanoma Hospitalization 2/1/2006 Female 5/25/2007 Physician France
Primary
Secondary
Liver Abscess Hospitalization 71 Female 5/29/2007 Physician Sweden
Primary
Secondary
Concomitant
Pneumonitis Death 62 Male 5/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Pneumonitis Death 62 Male 6/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 110 lb 6/8/2007 Physician Finland
Primary
Secondary
Methaemoglobinaemia Life Threatening 4/26/2007 Female 141 lb 6/13/2007 Other Health Professional France
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 110 lb 6/14/2007 Physician Finland
Primary
Secondary
Respiratory Failure Other Serious 62 Female 6/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2007 49 Female 6/20/2007 Consumer Netherlands
Primary
Concomitant
Respiratory Failure Other Serious 62 Female 6/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/2/2007 Female 179 lb 6/25/2007 Physician United Kingdom
Primary
Concomitant
Fibroma Hospitalization 40 Female 6/26/2007 Physician France
Primary
Concomitant
Swelling Face Other Serious 5/25/2007 58 Male 190 lb 6/28/2007 Physician United Kingdom
Primary
Concomitant
Death Life Threatening 3/30/2007 Female 7/6/2007 Consumer United Kingdom
Primary
Concomitant
Swelling Face Other Serious 5/25/2007 58 Male 190 lb 7/10/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 7/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 12/24/2006 67 Male 7/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 62 Female 7/13/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2007 Female 7/13/2007 Physician United Kingdom
Primary
Concomitant
Vitreous Detachment Disability 3/10/2007 Female 7/25/2007 Physician France
Primary
Secondary
Concomitant
Sepsis Death 6/16/2007 Male 7/26/2007 Physician Australia
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 9/5/2007 54 Male 10/29/2007 Consumer Norway
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 1/1/2005 Male 10/31/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 6/1/2007 Male 11/2/2007 Physician Norway
Primary
Secondary
Concomitant
Sense Of Oppression Hospitalization 10/15/2006 60 Female 11/10/2007 Physician Lebanon
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 6/1/2007 Male 11/12/2007 Physician Norway
Primary
Secondary
Concomitant
Soft Tissue Infection Hospitalization 65 Female 11/12/2007 Physician United Kingdom
Primary
Concomitant
Pancytopenia Life Threatening 10/4/2007 66 Female 99 lb 11/12/2007 Physician Portugal
Primary
Secondary
Concomitant
Pharyngitis Streptococcal Hospitalization 9/17/2007 50 Male 11/13/2007 Physician France
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 70 Male 11/13/2007 Physician France
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 6/1/2007 54 Male 11/14/2007 Consumer Norway
Primary
Secondary
Concomitant
Breast Cancer Other Serious 8/14/2007 Female 132 lb 11/16/2007 Physician Germany
Primary
Secondary
Mucosal Inflammation Hospitalization 5/22/2007 57 Male 11/16/2007 Consumer United States
Primary
Secondary
Concomitant
Peritonitis Life Threatening 11/4/2007 Female 123 lb 11/16/2007 Other Health Professional Colombia
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 5/18/2007 62 Male 11/16/2007 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 10/4/2007 66 Female 99 lb 11/20/2007 Physician Portugal
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 66 Female 99 lb 11/21/2007 Physician Portugal
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 70 Male 159 lb 11/21/2007 Physician France
Primary
Concomitant
Pharyngitis Streptococcal Hospitalization 9/16/2007 Male 11/29/2007 Physician France
Primary
Secondary
Concomitant
Peritonitis Life Threatening 11/4/2007 Female 123 lb 11/30/2007 Other Health Professional Colombia
Primary
Concomitant
Intestinal Adenocarcinoma Hospitalization 9/6/2007 73 Female 12/3/2007 Physician Denmark
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 9/6/2006 Female 12/3/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 9/6/2007 Female 12/4/2007 Physician Denmark
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 3/1/2007 Female 121 lb 12/10/2007 Physician Colombia
Primary
Concomitant
Paranoia Other Serious Male 12/11/2007 Physician United Kingdom
Primary
Secondary
Bone Marrow Failure Hospitalization 5/27/2007 Male 12/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Periorbital Cellulitis Other Serious Male 12/17/2007 Consumer Colombia
Primary
Concomitant
Osteomyelitis Other Serious 3/1/2007 Female 121 lb 12/18/2007 Physician Colombia
Primary
Concomitant
Lymphoma Other Serious 8/1/2007 71 Male 12/18/2007 Consumer United Kingdom
Primary
Concomitant
Hypoxia Hospitalization 12/8/2006 56 Female 12/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 5/6/2007 55 Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Pseudomonal Sepsis Hospitalization 79 Female 1/15/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious 8/1/2007 Male 1/15/2008 Physician Australia
Primary
Concomitant
Vomiting Other Serious 12/17/2007 69 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 12/21/2007 46 Male 157 lb 1/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Neoplasm Death Male 1/29/2008 Physician Germany
Primary
Concomitant
Pulmonary Tuberculosis Life Threatening 12/21/2007 46 Male 157 lb 1/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pseudomonal Sepsis Hospitalization Female 1/31/2008 Physician United Kingdom
Primary
Concomitant
Coronary Artery Stenosis Other Serious 1/1/2007 70 Female 1/31/2008 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/11/2007 46 Female 225 lb 1/31/2008 Consumer United Kingdom
Primary
Concomitant
Tuberculosis Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Somnolence Death 12/19/2007 Male 176 lb 2/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 2/11/2008 Consumer United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 2/4/2008 48 Female 2/20/2008 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Death 76 Female 98 lb 2/21/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 12/1/2007 Male 163 lb 2/25/2008 Physician United Kingdom
Primary
Concomitant
Uterine Haemorrhage Hospitalization 1/6/2008 Female 2/25/2008 Physician United Kingdom
Primary
Concomitant
Oesophageal Candidiasis Other Serious 3/13/2008 Physician United Kingdom
Primary
Concomitant
Aids Dementia Complex Death 3/13/2008 Physician United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 3/13/2008 Physician United Kingdom
Primary
Concomitant
Death Death 3/13/2008 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 3/13/2008 Physician United Kingdom
Primary
Concomitant
Escherichia Infection Death 3/13/2008 Physician United Kingdom
Primary
Concomitant
Hepatic Failure Death 3/13/2008 Physician United Kingdom
Primary
Concomitant
Multi-organ Failure Death 3/13/2008 Pharmacist United Kingdom
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 3/13/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 5/6/2007 Male 229 lb 3/25/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/14/2008 Male 3/28/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 4/3/2008 Consumer United States
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 3/18/2008 23 Female 4/3/2008 Physician United Kingdom
Primary
Concomitant
Oesophageal Carcinoma Death 7/1/2007 Male 4/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophageal Adenocarcinoma Metastatic Death 5/1/2006 Male 4/10/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pancytopenia Other Serious Male 4/11/2008 Other Health Professional Greece
Primary
Concomitant
Renal Failure Hospitalization 7/21/2007 Male 4/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/25/2007 47 Female 4/14/2008 Consumer France
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 1/25/2008 Female 132 lb 4/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/27/2008 Male 4/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinusitis Disability 10/4/2007 55 Female 4/25/2008 France
Primary
Secondary
Tremor Other Serious 20 Female 4/25/2008 Consumer United Kingdom
Primary
Concomitant
Breast Cancer Life Threatening 9/1/2007 58 Female 5/2/2008 Consumer United Kingdom
Primary
Secondary
Tremor Other Serious 12/1/2006 49 5/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Disability 10/4/2007 55 Female 5/9/2008 Physician United Kingdom
Primary
Secondary
Splenomegaly Hospitalization 3/18/2008 23 Female 5/14/2008 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/14/2008 Male 161 lb 5/16/2008 Consumer Belgium
Primary
Concomitant
Herpes Virus Infection Other Serious Female 132 lb 5/19/2008 Physician Poland
Primary
Concomitant
Myalgia Other Serious 9/19/2007 54 Female 5/27/2008 Physician United Kingdom
Primary
Concomitant
Headache Hospitalization 4/17/2008 Male 5/27/2008 Physician United Kingdom
Primary
Concomitant
Pleurisy Hospitalization 3/22/2008 Female 5/27/2008 Consumer United Kingdom
Primary
Concomitant
Stomatitis Other Serious 5/5/2008 58 Female 5/28/2008 Consumer United States
Primary
Secondary
Herpes Virus Infection Other Serious Female 132 lb 6/3/2008 Physician Poland
Primary
Concomitant
Arthritis Other Serious 5/14/2008 17 Male 6/5/2008 Physician United Kingdom
Primary
Concomitant
Splenomegaly Hospitalization 3/18/2008 23 Female 6/6/2008 Physician United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 5/13/2008 Female 106 lb 6/9/2008 Physician Colombia
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/1/2005 65 Male 6/10/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Death 12/1/2006 62 Male 6/11/2008 Consumer United States
Primary
Secondary
Hip Fracture Hospitalization 3/27/2008 Female 6/17/2008 Consumer United Kingdom
Primary
Concomitant
Neoplasm Other Serious Female 6/18/2008 Physician United Kingdom
Primary
Concomitant
Cryptogenic Organising Pneumonia Other Serious 64 Female 6/24/2008 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/15/2008 Female 6/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 6/16/2008 41 Male 6/25/2008 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 34 Female 6/25/2008 Physician France
Primary
Concomitant
Stomatitis Other Serious Female 6/26/2008 Other Health Professional France
Primary
Secondary
Blood Alkaline Phosphatase Increased Other Serious 6/4/2008 59 Female 6/26/2008 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 6/16/2008 Female 6/27/2008 Physician United Kingdom
Primary
Concomitant
Stomatitis Other Serious 7/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 60 Female 7/3/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Death 6/1/2008 60 Female 7/3/2008 Consumer United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 2/28/2008 Female 7/3/2008 Other Health Professional Italy
Primary
Concomitant
Breast Cancer Other Serious 67 Female 7/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data