Methotrexate combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Hospitalization 71 Male 1/2/2006
Primary
Concomitant
Urinary Incontinence Other Serious 5/19/2005 Male 152 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Peripheral Embolism Other Serious 12/15/2004 Female 1/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Blindness Other Serious Male 1/25/2006 Sweden
Primary
Concomitant
Malaise Other Serious 10/1/2005 61 Male 1/27/2006 Sweden
Primary
Secondary
Concomitant
Urinary Retention Death 10/21/2005 Male 192 lb 2/3/2006 United Kingdom
Primary
Concomitant
Weight Increased Life Threatening 4/22/2005 Male 254 lb 2/13/2006 United States
Primary
Concomitant
Palpitations Other Serious 1/13/2006 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/1/2005 41 Male 202 lb 1/23/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 7/8/2005 Male 3/1/2006 Physician United States
Primary
Concomitant
Tooth Infection Other Serious 10/1/2005 61 Male 2/27/2006 Physician Sweden
Primary
Secondary
Concomitant
Pelvic Mass Hospitalization 9/1/2005 79 3/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hemiparesis Required Intervention 12/21/2005 63 Male 276 lb 3/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2002 47 Female 240 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Hip Surgery Hospitalization 12/7/2005 51 Female 3/13/2006 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 5/4/2005 49 Female 3/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/1/2006 Female 180 lb 4/7/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/6/2006 Female 4/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 6/3/2002 70 Male 130 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Death 5/5/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2002 49 Female 236 lb 5/9/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2003 57 Male 5/9/2006 Australia
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Other Serious 4/13/2006 51 Female 5/24/2006 Physician Portugal
Primary
Concomitant
Staphylococcal Infection Hospitalization 7/1/2005 Female 108 lb 5/26/2006 Physician United States
Primary
Concomitant
Death Life Threatening 4/1/2006 Female 187 lb 5/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Carotid Artery Occlusion Other Serious 5/14/2006 Male 156 lb 6/5/2006 Consumer United States
Primary
Concomitant
Sleep Disorder Disability 4/6/2006 65 Female 97 lb 6/7/2006 Pharmacist United Kingdom
Primary
Concomitant
Cardiomyopathy Life Threatening 4/22/2005 Male 254 lb 6/16/2006 United States
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 6/27/2006 Physician Japan
Primary
Concomitant
Sepsis Life Threatening Female 187 lb 7/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 7/14/2006 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Pancreatitis Hospitalization 2/24/2006 Female 7/19/2006 Physician Belgium
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/14/2006 Pharmacist Canada
Primary
Concomitant
Bradycardia Hospitalization 6/12/2006 65 Male Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Ventricular Tachycardia Life Threatening 9/9/2006 Female 138 lb 9/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 150 lb 10/16/2006 United States
Primary
Secondary
Concomitant
Throat Cancer Other Serious 8/3/2006 Male 187 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 66 Male 12/13/2006 United States
Primary
Concomitant
Sepsis Syndrome Required Intervention 5/31/2006 70 Female 12/15/2006 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 2/1/2006 Female 180 lb 12/21/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 6/28/2005 59 Female 190 lb 1/9/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Concomitant
Gingival Bleeding 7/18/2006 40 Female 235 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Vomiting 9/9/2006 67 Male 192 lb 10/24/2006 United States
Primary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Death Death 12/1/2006 81 Female 1/8/2007 Consumer Canada
Primary
Concomitant
Somnolence Other Serious 6/28/2005 59 Female 190 lb 2/1/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 3/8/2007 Other Health Professional Sweden
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 11/1/2006 Male 179 lb 3/12/2007 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 79 Male 220 lb 3/7/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 79 Male 3/9/2007 United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 79 Male 3/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 79 Male 220 lb 3/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
B-cell Lymphoma Other Serious 2/13/2007 Male 181 lb 3/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sweat Discolouration 64 Male 3/27/2007 Physician United States
Primary
Concomitant
Hyperhidrosis 62 Male 185 lb 3/27/2007 Physician United States
Primary
Concomitant
Arthropathy Hospitalization Female 200 lb 3/28/2007 Consumer Canada
Primary
Concomitant
Pharyngolaryngeal Pain 10/2/2006 40 Female 235 lb 1/23/2007 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 11/1/2006 Male 179 lb 4/11/2007 Physician United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 8/17/2006 Female 134 lb 4/13/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Death Male 223 lb 4/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2005 Male 247 lb 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death Male 271 lb 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 5/4/2007 Other Health Professional Sweden
Primary
Concomitant
Pulmonary Fibrosis Hospitalization Female 5/10/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Emphysema Other Serious 1/7/2003 Female 187 lb 5/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious 79 Male 220 lb 5/14/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Death 79 Male 220 lb 5/15/2007 Physician United Kingdom
Primary
Concomitant
Death Death 4/1/2007 Male 187 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 4/15/2004 Female 157 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 10/28/2006 42 Male 1/14/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 79 Male 220 lb 5/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 79 Male 220 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pharyngeal Inflammation Hospitalization 4/1/2007 Female 216 lb 6/14/2007 Consumer Brazil
Primary
Concomitant
Hypersensitivity 5/1/2007 72 Male 185 lb 6/4/2007 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 141 lb 6/18/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Spinal Fracture Other Serious 2/1/2007 Female 121 lb 6/25/2007 Physician United States
Primary
Concomitant
Bladder Cancer Other Serious 6/18/2007 Female 190 lb 6/28/2007 Consumer United States
Primary
Concomitant
Pancytopenia Death 4/24/2007 82 Female 6/21/2007 Czech Republic
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 141 lb 6/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Soft Tissue Infection Other Serious 1/17/2007 Male 271 lb 7/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 7/5/2007 Physician Italy
Primary
Concomitant
Bradycardia Other Serious 3/10/2007 63 Male 7/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Death Female 97 lb 7/19/2007 Other Health Professional Canada
Primary
Concomitant
Pulmonary Arterial Pressure Increased Other Serious 33 Female 8/1/2007 Korea, Republic Of
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 74 Male 7/26/2007 Consumer United Kingdom
Primary
Concomitant
Death Other Serious Male 185 lb 8/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious 1/1/2004 Female 175 lb 8/23/2007 United States
Primary
Concomitant
Respiratory Failure Other Serious 6/4/2007 Female 122 lb 8/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/27/2007 Other Health Professional Sweden
Primary
Concomitant
Swelling Hospitalization 8/1/2007 Female 184 lb 8/30/2007 Consumer United States
Primary
Concomitant
Regurgitation Other Serious 7/20/2007 Male 175 lb 8/31/2007 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 185 lb 9/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 8/4/2007 69 Male 284 lb 9/17/2007 Physician United States
Primary
Concomitant
Weight Increased 2/1/2007 60 Female 220 lb 9/26/2007 Consumer United States
Primary
Concomitant
Rash 62 Female 249 lb 9/26/2007 Consumer United States
Primary
Concomitant
Bronchial Carcinoma Other Serious 7/1/2007 Male 10/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Other Serious 9/26/2007 Male 10/26/2007 Physician Australia
Primary
Concomitant
Regurgitation Other Serious 7/20/2007 Male 175 lb 10/26/2007 Consumer United States
Primary
Concomitant
Pancytopenia Life Threatening 10/4/2007 66 Female 99 lb 10/29/2007 Physician Portugal
Primary
Secondary
Concomitant
Synovial Rupture Other Serious 5/1/2005 42 Female 10/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 141 lb 11/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 7/1/2007 Male 185 lb 11/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 11/6/2007 United Kingdom
Primary
Concomitant
Pancytopenia Life Threatening 10/4/2007 66 Female 99 lb 11/12/2007 Physician Portugal
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/8/2007 Male 163 lb 11/13/2007 Pharmacist United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9/20/2007 Male 196 lb 11/16/2007 United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 8/14/2007 70 Female 11/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urosepsis Other Serious 10/1/2007 Female 11/20/2007 Other Health Professional Canada
Primary
Concomitant
Pyrexia Hospitalization 8/1/2007 Male 560 lb 11/20/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Decreased Life Threatening 44 Female 152 lb 11/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Death Death Male 187 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 7/5/2007 Male 172 lb 12/10/2007 United States
Primary
Concomitant
Myocardial Ischaemia Death 10/31/2007 Female 183 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Oral Candidiasis Female 160 lb 12/14/2007 United States
Primary
Concomitant
Drug Ineffective 9/1/2007 Female 200 lb 12/14/2007 Consumer United States
Primary
Concomitant
Accidental Exposure 9/30/2007 Female 201 lb 12/14/2007 Consumer United States
Primary
Concomitant
Vomiting 9/29/2007 Female 224 lb 12/14/2007 Consumer United States
Primary
Concomitant
Pain 9/1/2007 Female 130 lb 12/14/2007 United States
Primary
Concomitant
Hot Flush 10/28/2007 Female 12/14/2007 United States
Primary
Concomitant
Urinary Tract Infection 9/13/2007 Female 105 lb 12/14/2007 United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 7/5/2007 Male 172 lb 12/20/2007 United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/20/2007 Female 181 lb 12/21/2007 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 8/10/2007 Female 181 lb 12/28/2007 United Kingdom
Primary
Concomitant
Synovial Rupture Other Serious 5/1/2005 42 Female 1/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious 8/1/2007 Male 1/15/2008 Physician Australia
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 3/26/2007 Female 110 lb 2/1/2008 United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 1/3/2008 Female 107 lb 2/8/2008 Physician Belgium
Primary
Concomitant
Skin Ulcer Life Threatening 3/8/2007 Male 163 lb 2/13/2008 Pharmacist United Kingdom
Primary
Concomitant
Vestibular Disorder Other Serious 1/1/2005 Female 2/15/2008 Other Health Professional Canada
Primary
Concomitant
Herpes Zoster Other Serious 2/4/2008 48 Female 2/20/2008 Consumer United Kingdom
Primary
Concomitant
Subdural Haemorrhage Death Male 187 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2003 Female 123 lb 2/26/2008 Physician United Kingdom
Primary
Concomitant
Oropharyngeal Blistering Other Serious 1/7/2008 Male 161 lb 3/4/2008 Physician United Kingdom
Primary
Concomitant
Haemorrhage Hospitalization 64 Female 3/11/2008 Pharmacist United States
Primary
Secondary
Concomitant
Sinus Congestion 12/9/2007 Female 105 lb 3/14/2008 United States
Primary
Concomitant
Nasopharyngitis 12/30/2007 Female 138 lb 3/15/2008 Consumer United States
Primary
Concomitant
Confusional State 1/11/2008 Male 173 lb 3/15/2008 Physician United States
Primary
Concomitant
Vision Blurred 1/25/2008 Female 260 lb 3/15/2008 United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 11/19/2007 Female 3/25/2008 Physician Canada
Primary
Concomitant

Drug Data