Lorazepam combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Resuscitation Life Threatening 11/30/2005 Female 134 lb 1/13/2006 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2005 Female 1/18/2006 United Kingdom
Primary
Concomitant
Hepatic Failure Hospitalization 10/26/2005 44 Female 1/24/2006 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 3/9/2006 Consumer Canada
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 3/13/2006 Lawyer United States
Primary
Concomitant
Sedation Hospitalization 6/16/2003 49 Female 231 lb 3/23/2006 Physician United States
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Tuberculosis Hospitalization 2/1/2004 Female 132 lb 3/23/2006 France
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 3/23/2006 Physician Canada
Primary
Concomitant
Paraesthesia Required Intervention 3/18/2006 Female 90 lb 3/27/2006 Other Health Professional United States
Primary
Concomitant
Breast Cancer Other Serious 8/22/2005 Female 4/14/2006 Physician United States
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 4/21/2006 Physician Canada
Primary
Concomitant
Sepsis Death 2/7/2006 59 Male 5/3/2006 Pharmacist United States
Primary
Concomitant
Adenocarcinoma Other Serious 5/5/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/26/2006 Female 135 lb 5/11/2006 Physician Canada
Primary
Concomitant
Metastasis Other Serious 10/15/2001 60 Male 5/12/2006 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/13/2006 81 Female 5/24/2006 Physician France
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/6/2006 53 Male 6/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/15/2004 Female 192 lb 7/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 2/1/2004 Female 132 lb 7/31/2006 France
Primary
Concomitant
Syncope Hospitalization 1/1/2006 Female 156 lb 8/18/2006 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 5/13/2004 Female 100 lb 9/6/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/22/2006 51 Male 9/26/2006 Physician Belgium
Primary
Concomitant
Cystitis Noninfective Hospitalization 3/17/2006 73 Female 10/12/2006 Physician Belgium
Primary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/24/2006 70 Female 112 lb 10/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Retinal Oedema Life Threatening 5/15/2004 Female 192 lb 10/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 66 Female 12/4/2006 Physician Finland
Primary
Secondary
Concomitant
Confusional State Other Serious 10/15/2006 60 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Nasopharyngitis 9/5/2006 Female 12/19/2006 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 9/30/2006 Female 166 lb 12/22/2006 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 1/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious Female 2/1/2007 Other Health Professional Canada
Primary
Concomitant
Neutropenia Other Serious 12/14/2006 60 Female 128 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Life Threatening 1/12/2007 72 Female 226 lb 3/8/2007 Physician United States
Primary
Concomitant
Pancytopenia Death 3/10/2007 37 Female 165 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Life Threatening 1/12/2007 72 Female 226 lb 3/21/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2007 72 Female 99 lb 4/27/2007 Physician Spain
Primary
Concomitant
Disease Progression Other Serious Female 117 lb 6/4/2007 Consumer Canada
Primary
Concomitant
Cardiac Flutter Other Serious 3/1/2003 68 Female 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 117 lb 6/22/2007 Consumer Canada
Primary
Concomitant
Renal Impairment Hospitalization Female 6/26/2007 Consumer Canada
Primary
Concomitant
Osteonecrosis Hospitalization 4/30/2007 Male 6/28/2007 Physician United States
Primary
Secondary
Rheumatoid Nodule Hospitalization 5/28/2007 Female 145 lb 6/29/2007 Consumer Canada
Primary
Concomitant
Rheumatoid Nodule Hospitalization 5/28/2007 Female 145 lb 7/20/2007 Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2005 Female 7/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2006 Female 110 lb 7/27/2007 Canada
Primary
Concomitant
Femur Fracture Other Serious 6/26/2007 63 Female 200 lb 8/5/2007 Consumer United States
Primary
Concomitant
Hepatitis Other Serious 1/1/2006 70 Male 139 lb 8/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2003 68 Female 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 14 Male 10/17/2007 Other Health Professional United States
Primary
Concomitant
Nervous System Disorder Hospitalization 4/1/2007 Female 10/18/2007 Physician France
Primary
Concomitant
Quadriplegia Hospitalization 4/1/2007 Female 170 lb 10/22/2007 Physician France
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 5/1/2007 Female 11/16/2007 Belgium
Primary
Concomitant
Shock Hospitalization 10/21/2007 Male 84 lb 11/13/2007 United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 10/30/2006 Male 11/21/2007 Belgium
Primary
Concomitant
Septic Shock Hospitalization 10/21/2007 Male 84 lb 11/27/2007 United States
Primary
Secondary
Concomitant
Stress At Work 3/11/2007 Female 12/11/2007 Physician United States
Primary
Concomitant
Staphylococcal Infection 7/1/2007 Female 129 lb 12/14/2007 United States
Primary
Concomitant
Sinusitis 1/1/2004 Female 158 lb 12/15/2007 Consumer United States
Primary
Concomitant
Spinal Osteoarthritis 8/23/2007 Female 155 lb 12/15/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 8/1/2007 Female 173 lb 1/7/2008 Physician United States
Primary
Secondary
Concomitant
Polyp Other Serious 14 Male 1/11/2008 United States
Primary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 57 Female 249 lb 2/20/2008 Consumer United States
Primary
Concomitant
Shock Hospitalization 10/21/2007 Male 84 lb 2/20/2008 United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/20/2004 67 Male 2/22/2008 Physician Germany
Primary
Secondary
Concomitant
Surgery Hospitalization 9/27/2004 29 Male 2/26/2008 Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/27/2004 Male 2/29/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Skin Laceration 11/24/2007 Female 155 lb 3/14/2008 United States
Primary
Concomitant
Vomiting Hospitalization 3/15/2008 43 Female 128 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
Exsanguination Life Threatening 10/23/1986 23 Male 154 lb 3/31/2008 Physician United Kingdom
Primary
Concomitant
Hemiparesis Hospitalization 1/30/2008 57 Female 249 lb 4/3/2008 Other Health Professional United States
Primary
Concomitant
Tuberculosis Hospitalization 2/1/2004 Female 132 lb 4/25/2008 France
Primary
Concomitant
Pelvic Fracture Other Serious 1/1/2008 Female 5/12/2008 Consumer United States
Primary
Concomitant
Withdrawal Syndrome 9/21/2007 5/13/2008 Consumer United States
Primary
Concomitant
Tricuspid Valve Disease Other Serious 3/20/2008 60 Male 197 lb 5/15/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/1/2008 Female 210 lb 6/5/2008 Consumer United States
Primary
Concomitant
Overdose 3/17/2008 Female 232 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Obesity 5/4/2007 Female 160 lb 6/13/2008 United States
Primary
Concomitant
Injection Site Bruising 5/23/2008 Female 198 lb 6/13/2008 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 3/19/2005 79 Female 98 lb 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Other Serious 4/6/2008 Male 162 lb 6/23/2008 United States
Primary
Concomitant
Hernia Other Serious 3/12/2008 Female 165 lb 7/3/2008 United States
Primary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
Pemphigoid Other Serious 4/6/2008 Male 162 lb 7/17/2008 United States
Primary
Concomitant
Hypoaesthesia Hospitalization Male 7/18/2008 Consumer United States
Primary
Concomitant
Pemphigoid Other Serious 4/6/2008 Male 162 lb 7/22/2008 United States
Primary
Concomitant
Wound Other Serious 4/6/2008 Male 162 lb 8/27/2008 United States
Primary
Concomitant
Transverse Sinus Thrombosis Hospitalization 8/28/2008 Male 197 lb 9/3/2008 United States
Primary
Secondary
Concomitant
Dysphagia 7/23/2008 Female 9/4/2008 Pharmacist United States
Primary
Concomitant
Contusion 7/3/2008 Female 158 lb 9/12/2008 United States
Primary
Concomitant
Rash 4/1/2008 Female 160 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Urticaria 6/1/2008 Female 147 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Irritation 7/14/2008 Female 101 lb 9/12/2008 Consumer United States
Primary
Concomitant
Overdose 3/17/2008 Female 232 lb 9/13/2008 Pharmacist United States
Primary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 10/15/2001 60 Male 9/16/2008 United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/30/2008 Male 183 lb 9/19/2008 Canada
Primary
Secondary
Concomitant
Infusion Related Reaction Hospitalization 11/12/2007 Male 275 lb 9/22/2008 Physician United States
Primary
Concomitant
Weight Decreased 11/1/2007 63 Female 154 lb 9/25/2008 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 10/10/2008 Canada
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 1/1/2008 Female 138 lb 10/13/2008 United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 10/24/2008 Canada
Primary
Secondary
Concomitant
Swelling Other Serious Female 10/27/2008 Physician United States
Primary
Concomitant
Swelling Other Serious Female 10/31/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/1/2008 Female 230 lb 11/13/2008 United States
Primary
Concomitant
Pleural Effusion Hospitalization 8/30/2008 Male 183 lb 11/14/2008 Canada
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization Male 216 lb 11/14/2008 Physician Belgium
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 8/4/2005 Female 121 lb 11/17/2008 Consumer United Kingdom
Primary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 11/24/2008 Consumer France
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 46 Female 12/4/2008
Primary
Secondary
Concomitant
Weight Increased Hospitalization 2/28/2005 Female 167 lb 12/5/2008 Physician United States
Primary
Concomitant
Tremor 2/8/2008 Male 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Rash 4/1/2008 Female 160 lb 12/12/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Visual Impairment 4/1/2008 Female 250 lb 12/12/2008 United States
Primary
Concomitant
Rheumatoid Arthritis 6/1/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Wheezing 9/5/2008 Female 214 lb 12/12/2008 United States
Primary
Concomitant
Cough 9/12/2008 Female 150 lb 12/12/2008 United States
Primary
Concomitant
Injection Site Pain 9/24/2008 Female 275 lb 12/12/2008 Consumer United States
Primary
Concomitant
Nephrotic Syndrome Hospitalization 10/14/2008 Male 216 lb 12/12/2008 Belgium
Primary
Secondary
Concomitant
Nasopharyngitis 10/2/2008 Female 128 lb 12/12/2008 United States
Primary
Concomitant
Hernia 5/1/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Incorrect Dose Administered 10/31/2008 Female 150 lb 12/12/2008 Consumer United States
Primary
Concomitant
Pyrexia 11/10/2008 Female 12/12/2008 United States
Primary
Concomitant
Incorrect Dose Administered 11/24/2008 Female 149 lb 12/12/2008 United States
Primary
Concomitant
Sinusitis Other Serious 4/1/2002 12/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 10/20/2008 74 Female 12/19/2008 Physician Netherlands
Primary
Concomitant
Weight Increased Hospitalization 2/28/2005 Female 167 lb 12/23/2008 Physician United States
Primary
Concomitant
Respiratory Disorder Other Serious 12/9/2008 Female 154 lb 1/30/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/25/2008 62 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Concomitant
Palpitations Hospitalization 11/1/2008 40 Female 2/6/2009 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 8/4/2005 Female 121 lb 2/24/2009 Consumer United Kingdom
Primary
Concomitant
Ileostomy Hospitalization Male 2/26/2009 Physician United Kingdom
Primary
Concomitant
Infection 10/2/2008 Female 2/27/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 2/1/2009 Male 181 lb 3/9/2009 Canada
Primary
Concomitant
Tinnitus Other Serious 2/1/2009 Male 181 lb 3/11/2009 Canada
Primary
Concomitant
Plantar Fasciitis 6/1/2007 Female 220 lb 3/14/2009 United States
Primary
Concomitant
Rectal Haemorrhage 11/1/2008 Female 189 lb 3/14/2009 United States
Primary
Secondary
Concomitant
Hypophagia 11/11/2008 Male 190 lb 3/14/2009 Consumer United States
Primary
Secondary
Concomitant
Insomnia 12/1/2008 Female 160 lb 3/14/2009 Consumer United States
Primary
Concomitant
Stomatitis 2/7/2009 Female 180 lb 3/14/2009 Physician United States
Primary
Concomitant
Injection Site Pain Female 157 lb 3/14/2009 Consumer United States
Primary
Concomitant

Drug Data