Hydrocodone combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Basal Cell Carcinoma Other Serious 9/1/2005 Female 3/1/2006 Physician United States
Primary
Concomitant
Synovitis Hospitalization 57 Male 2/27/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 170 lb 2/28/2006 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 1/9/2006 67 Female 3/22/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2002 61 Female 198 lb 3/20/2006 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 8/1/2005 Female 150 lb 4/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 11/7/2005 Female 134 lb 4/20/2006 Physician United States
Primary
Secondary
Concomitant
Renal Artery Stenosis Hospitalization 11/15/2005 Female 5/12/2006 Physician United States
Primary
Concomitant
Erythema Nodosum Other Serious 5/1/2006 76 Female 187 lb 5/17/2006 Physician United States
Primary
Concomitant
Soft Tissue Necrosis Hospitalization 1/1/2005 Male 132 lb 6/9/2006 Physician United States
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 6/30/2006 Other Health Professional United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Female 7/10/2006 Physician United States
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 7/31/2006 Other Health Professional United States
Primary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 9/15/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 3/9/2006 Female 190 lb 11/2/2006 Physician United States
Primary
Concomitant
Confusional State Other Serious 10/15/2006 60 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Unclassifiable Death Female 12/8/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/15/2005 Male 248 lb 12/13/2006 Physician United States
Primary
Concomitant
Rash Generalised 6/1/2006 Female 12/13/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious 6/8/2006 Female 158 lb 1/16/2007 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis 62 Male 185 lb 3/27/2007 Physician United States
Primary
Concomitant
Pre-existing Condition Improved 1/1/2007 50 Female 201 lb 3/27/2007 Consumer United States
Primary
Concomitant
Stomatitis Hospitalization 3/1/2007 Female 203 lb 9/14/2007 Consumer United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 1/1/2007 Female 9/20/2007 Consumer United States
Primary
Concomitant
Ocular Hyperaemia Hospitalization 3/1/2007 Female 203 lb 10/23/2007 Consumer United States
Primary
Secondary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2002 Female 1/17/2008 Lawyer United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 351 lb 1/21/2008 Physician United States
Primary
Concomitant
Lymphoma Other Serious Female 3/11/2008 Physician United States
Primary
Concomitant
Pain 11/12/2007 Female 228 lb 6/12/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 3/3/2008 Female 164 lb 6/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 12/1/2007 Female 240 lb 6/12/2008 United States
Primary
Concomitant
Precancerous Skin Lesion 1/1/2008 Female 168 lb 6/12/2008 United States
Primary
Concomitant
Tinea Infection 3/31/2008 Female 151 lb 6/12/2008 Other Health Professional United States
Primary
Concomitant
Underdose 2/1/2008 Male 198 lb 6/12/2008 Consumer United States
Primary
Concomitant
Urticaria 1/1/2006 Female 155 lb 6/12/2008 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection 4/16/2008 Female 171 lb 6/13/2008 United States
Primary
Concomitant
Accidental Exposure 5/6/2008 Female 170 lb 6/13/2008 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 62 Male 6/23/2008 United States
Primary
Concomitant
Nasopharyngitis 55 Female 205 lb 6/30/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Bacterial Disability 7/1/2008 Female 236 lb 1/30/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/6/2009 Female 166 lb 7/16/2009 Physician United States
Primary
Concomitant
Pain Other Serious 7/1/2009 Male 7/31/2009 United States
Primary
Concomitant
Vomiting Hospitalization 5/6/2009 Female 166 lb 8/6/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2008 Male 175 lb 8/11/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Wrist Fracture Other Serious 6/1/2009 Female 134 lb 9/3/2009 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 6/1/2009 Male 9/3/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2008 Male 175 lb 9/4/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 7/1/2008 Female 103 lb 9/18/2009 United States
Primary
Concomitant
Pain 6/6/2009 Male 9/18/2009 United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2007 Female 9/19/2009 United States
Primary
Concomitant
Pain In Extremity 7/1/2009 Female 200 lb 9/19/2009 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal 5/1/2008 Female 250 lb 9/19/2009 United States
Primary
Concomitant
Drug Dose Omission Female 215 lb 9/19/2009 Consumer United States
Primary
Concomitant
Pollakiuria 6/3/2009 Female 200 lb 9/19/2009 United States
Primary
Concomitant
Sleep Disorder 7/18/2005 54 Female 236 lb 9/23/2009 United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/1/2009 Female 260 lb 9/25/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/9/2009 Male 186 lb 10/13/2009 Physician United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 9/22/2009 55 Female 302 lb 10/8/2009 United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/1/2009 260 lb 10/15/2009 Consumer United States
Primary
Secondary
Concomitant
Heart Rate Decreased 10/18/2009 Female 10/26/2009 Consumer
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 6/1/2008 Female 131 lb 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Life Threatening 10/13/2009 181 lb 11/9/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 11/4/2009 Lawyer United States
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 10/29/2009 Male 139 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Hospitalization 6/16/2009 45 Female 154 lb 10/20/2009 Physician United States
Primary
Concomitant
Demyelination Other Serious 1/24/2009 Female 11/23/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/29/2009 Female 99 lb 11/13/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 82 Male 11/17/2009 United States
Primary
Concomitant
Prostate Cancer Other Serious 61 Male 11/30/2009 Physician United States
Primary
Concomitant
Latex Allergy Female 12/3/2009 Pharmacist
Primary
Concomitant
Influenza Like Illness 7/28/2009 45 Female 10/28/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 3/1/2009 Female 189 lb 12/8/2009 Physician United States
Primary
Concomitant
Sinus Congestion 6/15/2009 12/9/2009 Physician United States
Primary
Concomitant
Sepsis Death 10/15/2009 66 Male 240 lb 12/11/2009 Physician United States
Primary
Concomitant
Osteonecrosis Disability 12/1/2007 57 Female 11/25/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 12/10/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2004 Female 153 lb 12/18/2009 United States
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 10/29/2009 Male 139 lb 12/23/2009 Other Health Professional United States
Primary
Concomitant
Thrombophlebitis Hospitalization 11/1/2008 Male 214 lb 12/23/2009 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2008 Female 110 lb 12/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2009 Female 156 lb 1/5/2010 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2008 Male 225 lb 1/29/2010 Consumer United States
Primary
Concomitant
Injection Site Extravasation 9/8/2009 302 lb 1/29/2010 Consumer United States
Primary
Concomitant
Drug Effect Decreased 11/1/2008 Female 144 lb 1/29/2010 Physician United States
Primary
Concomitant
Drug Dose Omission 7/1/2009 Female 185 lb 1/29/2010 Consumer United States
Primary
Concomitant
Drug Dose Omission 9/15/2009 Female 170 lb 1/29/2010 United States
Primary
Concomitant
Staphylococcal Infection 3/1/2009 Female 145 lb 1/30/2010 Consumer United States
Primary
Concomitant
Thyroid Cancer Other Serious 10/1/2009 Female 1/30/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious Female 132 lb 2/4/2010 Physician United States
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/5/2010 Physician United States
Primary
Concomitant
Lung Adenocarcinoma Other Serious 1/6/2009 67 Male 2/22/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/26/2010 Pharmacist United States
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/26/2010 Physician United States
Primary
Concomitant
Viral Infection Hospitalization 9/22/2009 Female 300 lb 2/10/2010 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2009 Male 230 lb 3/9/2010 Consumer United States
Primary
Concomitant
Toothache Other Serious 4/14/2005 Female 127 lb 3/12/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 3/17/2010 Pharmacist United States
Primary
Concomitant
Wheezing Hospitalization 9/22/2009 Female 300 lb 3/15/2010 Physician United States
Primary
Concomitant
Palpitations Other Serious 3/1/2010 46 Female 142 lb 5/11/2010 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 3/1/2010 46 Female 142 lb 5/13/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 76 Male 156 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 76 Male 156 lb 5/18/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/19/2010 United States
Primary
Concomitant
Wheezing Hospitalization 9/22/2009 55 Female 300 lb 5/19/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/28/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 6/2/2010 Pharmacist United States
Primary
Concomitant
Thyroid Function Test Abnormal 1/1/2009 62 Female 172 lb 5/11/2010 Consumer United States
Primary
Secondary
Concomitant
Sluggishness Female 5/11/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 76 Male 156 lb 6/8/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 6/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 58 Female 6/18/2010 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 2/5/2010 47 Female 6/18/2010 Consumer United States
Primary
Concomitant
Urine Potassium Increased Hospitalization 11/9/2009 81 Male 203 lb 6/16/2010 United States
Primary
Concomitant
Pancreatitis Hospitalization Female 6/24/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/15/2010 71 Female 6/29/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 76 Male 156 lb 7/1/2010 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 6/24/2010 73 Female 170 lb 7/14/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting 11/5/2007 59 Female 115 lb 7/17/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/15/2010 71 Female 8/6/2010 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Other Serious 5/14/2007 58 Female 8/19/2010 Lawyer United States
Primary
Concomitant
Pulmonary Mass Other Serious 1/1/2009 66 Female 162 lb 9/2/2010 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/1/2009 77 Female 160 lb 9/3/2010 Physician
Primary
Concomitant
Tooth Disorder Hospitalization 1/1/2007 57 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization 8/1/2010 Female 9/8/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 9/13/2010 Pharmacist United States
Primary
Concomitant
Pancreatitis Hospitalization Female 9/16/2010 Physician United States
Primary
Concomitant
Poor Quality Sleep Other Serious 8/1/2007 57 Female 145 lb 9/22/2010 Physician United States
Primary
Concomitant
Tibia Fracture Other Serious 8/1/2010 48 Female 9/27/2010 Consumer United States
Primary
Concomitant
Tooth Disorder Hospitalization 1/1/2007 57 Female 9/30/2010 Other Health Professional United States
Primary
Concomitant
Tibia Fracture Other Serious 8/1/2010 48 Female 10/8/2010 Consumer United States
Primary
Concomitant
Tooth Infection Other Serious 1/1/2007 57 Female 10/14/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 10/20/2010 Pharmacist United States
Primary
Concomitant
Renal Cyst Other Serious 8/2/2010 72 Female 10/26/2010 Physician United States
Primary
Concomitant
Hypotension Hospitalization 8/23/2010 50 Female 11/5/2010 Physician Switzerland
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 11/9/2010 Pharmacist United States
Primary
Concomitant
Rash Papular Other Serious 6/1/2010 11/11/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/31/2004 57 Female 181 lb 11/15/2010 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 10/19/2010 46 Female 11/25/2010 Physician United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 3/1/2010 65 Male 118 lb 11/29/2010 Physician United States
Primary
Concomitant
Pain In Extremity 11/18/2010 68 Female 148 lb 12/9/2010 Consumer United States
Primary
Concomitant
Injection Site Warmth 9/10/2009 12/13/2010 Physician United States
Primary
Concomitant
Toothache 10/30/2009 12/14/2010 Consumer United States
Primary
Concomitant

Drug Data